IL111345A - Pharmaceutical emulsion comprising short acting calcium antagonist dihydropyridines - Google Patents

Pharmaceutical emulsion comprising short acting calcium antagonist dihydropyridines

Info

Publication number
IL111345A
IL111345A IL11134594A IL11134594A IL111345A IL 111345 A IL111345 A IL 111345A IL 11134594 A IL11134594 A IL 11134594A IL 11134594 A IL11134594 A IL 11134594A IL 111345 A IL111345 A IL 111345A
Authority
IL
Israel
Prior art keywords
dihydropyridines
short acting
pct
pharmaceutical emulsion
calcium antagonist
Prior art date
Application number
IL11134594A
Other languages
English (en)
Other versions
IL111345A0 (en
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of IL111345A0 publication Critical patent/IL111345A0/xx
Publication of IL111345A publication Critical patent/IL111345A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL11134594A 1993-11-12 1994-10-20 Pharmaceutical emulsion comprising short acting calcium antagonist dihydropyridines IL111345A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9303744A SE9303744D0 (sv) 1993-11-12 1993-11-12 Pharmaceutical emulsion

Publications (2)

Publication Number Publication Date
IL111345A0 IL111345A0 (en) 1994-12-29
IL111345A true IL111345A (en) 2000-08-31

Family

ID=20391731

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11134594A IL111345A (en) 1993-11-12 1994-10-20 Pharmaceutical emulsion comprising short acting calcium antagonist dihydropyridines

Country Status (31)

Country Link
US (1) US5739152A (es)
EP (1) EP0727997B1 (es)
JP (1) JP3759951B2 (es)
KR (1) KR100345627B1 (es)
CN (1) CN1072934C (es)
AT (1) ATE213158T1 (es)
AU (1) AU678650B2 (es)
CA (1) CA2176360C (es)
CZ (1) CZ290772B6 (es)
DE (1) DE69429871T2 (es)
DK (1) DK0727997T3 (es)
EE (1) EE03223B1 (es)
EG (1) EG20764A (es)
ES (1) ES2172572T3 (es)
FI (1) FI116999B (es)
HK (1) HK1013261A1 (es)
HU (1) HU223142B1 (es)
IL (1) IL111345A (es)
IS (1) IS2036B (es)
MY (1) MY121201A (es)
NO (1) NO314877B1 (es)
NZ (1) NZ276197A (es)
PL (1) PL181462B1 (es)
PT (1) PT727997E (es)
RU (1) RU2144358C1 (es)
SA (1) SA94150314B1 (es)
SE (1) SE9303744D0 (es)
SK (1) SK283271B6 (es)
UA (1) UA40633C2 (es)
WO (1) WO1995013066A1 (es)
ZA (1) ZA948180B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
CN1245955C (zh) * 1998-05-29 2006-03-22 斯凯伊药品加拿大公司 热保护微粒组合物及其最终蒸汽灭菌的方法
SE9804002D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New manufacturing process
DE10036871A1 (de) 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
US7387790B2 (en) 2001-06-15 2008-06-17 Cornerstone Pharmaceuticals Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells
PT1615646E (pt) 2003-04-08 2015-02-12 Progenics Pharm Inc Formulações farmacêuticas com metilnaltrexona
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) * 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
ES2570374T3 (es) * 2007-03-29 2016-05-18 Progenics Pharm Inc Antagonistas del receptor opioide periférico y usos de los mismos
PT2139890E (pt) * 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
MX351611B (es) 2007-03-29 2017-10-20 Wyeth Llc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
WO2009099411A1 (en) 2008-02-06 2009-08-13 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
WO2010014234A1 (en) * 2008-08-01 2010-02-04 The Medicines Company Pharmaceutical compositions and methods for stabilizing the same
SI2320740T1 (sl) * 2008-08-01 2014-08-29 The Medicines Company Farmacevtski sestavki clevidipina in postopki za izdelavo nizke koncentracije neäśistoäś le-teh
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
US9034389B2 (en) 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
JP6081058B2 (ja) * 2009-03-19 2017-02-15 第一三共株式会社 包装により安定保存された固形製剤
CN101780036B (zh) * 2010-03-30 2011-11-16 武汉武药科技有限公司 丁酸氯维地平脂微球注射液及其制备方法
US8658676B2 (en) 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
EA022849B1 (ru) 2010-10-12 2016-03-31 Дзе Медсинз Компани Эмульсионные композиции клевидипина, содержащие противомикробные агенты
CN102531998A (zh) * 2010-12-09 2012-07-04 天津药物研究院 α型多晶型丁酸氯维地平结晶、其制备方法、用途和药物组合物
CN102525918A (zh) * 2010-12-30 2012-07-04 天津药物研究院 一种丁酸氯维地平的脂肪乳注射液及其制备工艺
US20120213855A1 (en) * 2011-02-17 2012-08-23 Cima Labs Inc. Dosage forms for weakly ionizable compounds
BR112013025368A8 (pt) * 2011-04-01 2018-06-12 The Medicines Co Medicamento, método para preparar um medicamento útil para reduzir danos por derrame em um sujeito com derrame, método para preparar um medicamento útil para reduzir a pressão sanguínea e reduzir danos por derrame em um sujeito com derrame
CN104105472A (zh) 2011-12-20 2014-10-15 维奥姆生物科学有限公司 用于治疗真菌感染的局部油组合物
AU2013334081B2 (en) 2012-10-26 2017-05-18 Chiesi Farmaceutici S.P.A. Methods for controlling blood pressure and reducing dyspnea in heart failure
CN103110580B (zh) * 2013-02-20 2014-09-17 北京德立福瑞医药科技有限公司 丁酸氯维地平注射剂
EP2983714A2 (en) * 2013-04-12 2016-02-17 Vyome Biosciences Pvt. Ltd. Composition and formulation of antimicrobial agents, processes thereof and methods for treating microbial infections
RU2759673C2 (ru) 2014-05-19 2021-11-16 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Наночастицы клевидипина и их фармацевтические композиции

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315805A1 (de) * 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4217842A1 (de) * 1992-05-29 1993-12-02 Dietl Hans Calciumantagonisten enthaltende pharmazeutische Zubereitung zur intravenösen und intrakoronaren Applikation sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
AU1037195A (en) 1995-05-29
FI961999A0 (fi) 1996-05-10
CZ133896A3 (en) 1996-09-11
WO1995013066A1 (en) 1995-05-18
DE69429871T2 (de) 2002-08-22
PL181462B1 (pl) 2001-07-31
FI961999A (fi) 1996-05-10
EP0727997B1 (en) 2002-02-13
CA2176360A1 (en) 1995-05-18
IL111345A0 (en) 1994-12-29
SK59796A3 (en) 1996-12-04
PL314263A1 (en) 1996-09-02
CA2176360C (en) 2005-08-23
NO961898L (no) 1996-06-25
UA40633C2 (uk) 2001-08-15
SK283271B6 (sk) 2003-04-01
CZ290772B6 (cs) 2002-10-16
ES2172572T3 (es) 2002-10-01
HU223142B1 (hu) 2004-03-29
IS2036B (is) 2005-08-15
DE69429871D1 (de) 2002-03-21
NO961898D0 (no) 1996-05-10
EP0727997A1 (en) 1996-08-28
NZ276197A (en) 1997-04-24
JPH09505045A (ja) 1997-05-20
IS4224A (is) 1995-05-13
CN1136774A (zh) 1996-11-27
PT727997E (pt) 2002-07-31
HK1013261A1 (en) 1999-08-20
DK0727997T3 (da) 2002-04-22
CN1072934C (zh) 2001-10-17
FI116999B (fi) 2006-05-15
HU9601268D0 (en) 1996-07-29
EE03223B1 (et) 1999-10-15
ZA948180B (en) 1995-05-12
SA94150314B1 (ar) 2005-06-14
SE9303744D0 (sv) 1993-11-12
ATE213158T1 (de) 2002-02-15
EG20764A (en) 2000-01-31
US5739152A (en) 1998-04-14
HUT74474A (en) 1996-12-30
MY121201A (en) 2006-01-28
JP3759951B2 (ja) 2006-03-29
RU2144358C1 (ru) 2000-01-20
NO314877B1 (no) 2003-06-10
KR100345627B1 (ko) 2003-03-15
AU678650B2 (en) 1997-06-05

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