SK283271B6 - Farmaceutický prípravok vo forme emulzie na intravenózne podanie na krátkodobé zníženie krvného tlaku a spôsob jeho výroby - Google Patents
Farmaceutický prípravok vo forme emulzie na intravenózne podanie na krátkodobé zníženie krvného tlaku a spôsob jeho výroby Download PDFInfo
- Publication number
- SK283271B6 SK283271B6 SK597-96A SK59796A SK283271B6 SK 283271 B6 SK283271 B6 SK 283271B6 SK 59796 A SK59796 A SK 59796A SK 283271 B6 SK283271 B6 SK 283271B6
- Authority
- SK
- Slovakia
- Prior art keywords
- dihydropyridine
- methyl
- dimethyl
- dichlorophenyl
- dicarboxylate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9303744A SE9303744D0 (sv) | 1993-11-12 | 1993-11-12 | Pharmaceutical emulsion |
| PCT/SE1994/001032 WO1995013066A1 (en) | 1993-11-12 | 1994-11-03 | Pharmaceutical emulsion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK59796A3 SK59796A3 (en) | 1996-12-04 |
| SK283271B6 true SK283271B6 (sk) | 2003-04-01 |
Family
ID=20391731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK597-96A SK283271B6 (sk) | 1993-11-12 | 1994-11-03 | Farmaceutický prípravok vo forme emulzie na intravenózne podanie na krátkodobé zníženie krvného tlaku a spôsob jeho výroby |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US5739152A (es) |
| EP (1) | EP0727997B1 (es) |
| JP (1) | JP3759951B2 (es) |
| KR (1) | KR100345627B1 (es) |
| CN (1) | CN1072934C (es) |
| AT (1) | ATE213158T1 (es) |
| AU (1) | AU678650B2 (es) |
| CA (1) | CA2176360C (es) |
| CZ (1) | CZ290772B6 (es) |
| DE (1) | DE69429871T2 (es) |
| DK (1) | DK0727997T3 (es) |
| EE (1) | EE03223B1 (es) |
| EG (1) | EG20764A (es) |
| ES (1) | ES2172572T3 (es) |
| FI (1) | FI116999B (es) |
| HK (1) | HK1013261A1 (es) |
| HU (1) | HU223142B1 (es) |
| IL (1) | IL111345A (es) |
| IS (1) | IS2036B (es) |
| MY (1) | MY121201A (es) |
| NO (1) | NO314877B1 (es) |
| NZ (1) | NZ276197A (es) |
| PL (1) | PL181462B1 (es) |
| PT (1) | PT727997E (es) |
| RU (1) | RU2144358C1 (es) |
| SA (1) | SA94150314B1 (es) |
| SE (1) | SE9303744D0 (es) |
| SK (1) | SK283271B6 (es) |
| UA (1) | UA40633C2 (es) |
| WO (1) | WO1995013066A1 (es) |
| ZA (1) | ZA948180B (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030158220A1 (en) * | 1997-11-03 | 2003-08-21 | Foss Joseph F. | Use of methylnaltrexone and related compounds to treat chronic opioid use side effects |
| ATE259220T1 (de) * | 1998-05-29 | 2004-02-15 | Skyepharma Canada Inc | Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben |
| SE9804002D0 (sv) * | 1998-11-23 | 1998-11-23 | Astra Ab | New manufacturing process |
| DE10036871A1 (de) | 2000-07-28 | 2002-02-14 | Pharmasol Gmbh | Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe |
| KR100915741B1 (ko) | 2001-06-15 | 2009-09-04 | 코너스톤 파마슈티칼스 | 표적 조직 및 세포를 치료하기에 유용한 나노입자를함유하는 약제학적 및 진단학적 조성물 |
| CN104383542B (zh) | 2003-04-08 | 2017-09-26 | 普罗热尼奇制药公司 | 包含甲基纳曲酮的药物配方 |
| AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| AR057325A1 (es) * | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| TW200817048A (en) * | 2006-09-08 | 2008-04-16 | Wyeth Corp | Dry powder compound formulations and uses thereof |
| SI2139890T1 (sl) * | 2007-03-29 | 2014-12-31 | Wyeth Llc | Antagonisti perifernih opioidnih receptorjev in njih uporaba |
| PA8774201A1 (es) | 2007-03-29 | 2009-06-23 | Progenics Pharm Inc | Antagonista del receptor |
| MX351611B (es) | 2007-03-29 | 2017-10-20 | Wyeth Llc | Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas. |
| EP2730578A1 (en) | 2008-02-06 | 2014-05-14 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnal trexone |
| HUE047692T2 (hu) * | 2008-08-01 | 2020-05-28 | Chiesi Farm Spa | Gyógyászati készítmények és eljárások stabilizálásukra |
| PL2320740T3 (pl) * | 2008-08-01 | 2014-09-30 | The Medicines Co | Kompozycje farmaceutyczne klewidypiny oraz sposoby ich wytwarzania z niskim stężeniem zanieczyszczeń |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| US9034389B2 (en) * | 2009-03-11 | 2015-05-19 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
| US8993625B2 (en) | 2009-03-11 | 2015-03-31 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle |
| WO2010107081A1 (ja) * | 2009-03-19 | 2010-09-23 | 第一三共株式会社 | 包装により安定保存された固形製剤 |
| CN101780036B (zh) * | 2010-03-30 | 2011-11-16 | 武汉武药科技有限公司 | 丁酸氯维地平脂微球注射液及其制备方法 |
| US8658676B2 (en) * | 2010-10-12 | 2014-02-25 | The Medicines Company | Clevidipine emulsion formulations containing antimicrobial agents |
| HUE026295T2 (en) | 2010-10-12 | 2016-06-28 | The Medicines Co | Clevidipine emulsion formulations containing antimicrobial agents |
| CN102531998A (zh) * | 2010-12-09 | 2012-07-04 | 天津药物研究院 | α型多晶型丁酸氯维地平结晶、其制备方法、用途和药物组合物 |
| CN102525918A (zh) * | 2010-12-30 | 2012-07-04 | 天津药物研究院 | 一种丁酸氯维地平的脂肪乳注射液及其制备工艺 |
| US20120213855A1 (en) * | 2011-02-17 | 2012-08-23 | Cima Labs Inc. | Dosage forms for weakly ionizable compounds |
| CN103781479A (zh) | 2011-04-01 | 2014-05-07 | 医药公司 | 用于减轻中风损害的短效二氢吡啶（氯维地平） |
| KR102009698B1 (ko) | 2011-12-20 | 2019-08-13 | 바이옴 테라퓨틱스 리미티드 | 진균 감염의 치료를 위한 국소 오일 조성물 |
| EA030354B1 (ru) | 2012-10-26 | 2018-07-31 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Способ уменьшения диспноэ у пациента с острой сердечной недостаточностью |
| CN103110580B (zh) * | 2013-02-20 | 2014-09-17 | 北京德立福瑞医药科技有限公司 | 丁酸氯维地平注射剂 |
| EP2983714A2 (en) * | 2013-04-12 | 2016-02-17 | Vyome Biosciences Pvt. Ltd. | Composition and formulation of antimicrobial agents, processes thereof and methods for treating microbial infections |
| MX2016015208A (es) | 2014-05-19 | 2017-03-23 | The Medicines Co | Nanoparticulas de clevidipina y composiciones farmaceuticas que las contienen. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3315805A1 (de) * | 1983-04-30 | 1984-11-08 | Bayer Ag, 5090 Leverkusen | Wirkstoffzubereitungen |
| DE3339236A1 (de) * | 1983-10-28 | 1985-05-09 | Bayer Ag | Arzneimittelzubereitung |
| DE3515335C2 (de) * | 1985-04-27 | 1995-01-26 | Bayer Ag | Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung |
| DE4217842A1 (de) * | 1992-05-29 | 1993-12-02 | Dietl Hans | Calciumantagonisten enthaltende pharmazeutische Zubereitung zur intravenösen und intrakoronaren Applikation sowie Verfahren zu ihrer Herstellung |
-
1993
- 1993-11-12 SE SE9303744A patent/SE9303744D0/xx unknown
-
1994
- 1994-10-18 ZA ZA948180A patent/ZA948180B/xx unknown
- 1994-10-20 IL IL11134594A patent/IL111345A/xx not_active IP Right Cessation
- 1994-10-21 IS IS4224A patent/IS2036B/is unknown
- 1994-11-03 NZ NZ276197A patent/NZ276197A/en not_active IP Right Cessation
- 1994-11-03 DK DK95900965T patent/DK0727997T3/da active
- 1994-11-03 PT PT95900965T patent/PT727997E/pt unknown
- 1994-11-03 JP JP51375695A patent/JP3759951B2/ja not_active Expired - Lifetime
- 1994-11-03 AU AU10371/95A patent/AU678650B2/en not_active Expired
- 1994-11-03 PL PL94314263A patent/PL181462B1/pl unknown
- 1994-11-03 WO PCT/SE1994/001032 patent/WO1995013066A1/en active IP Right Grant
- 1994-11-03 CN CN94194111A patent/CN1072934C/zh not_active Expired - Lifetime
- 1994-11-03 EE EE9600052A patent/EE03223B1/xx unknown
- 1994-11-03 AT AT95900965T patent/ATE213158T1/de active
- 1994-11-03 HU HU9601268A patent/HU223142B1/hu active IP Right Grant
- 1994-11-03 DE DE69429871T patent/DE69429871T2/de not_active Expired - Lifetime
- 1994-11-03 ES ES95900965T patent/ES2172572T3/es not_active Expired - Lifetime
- 1994-11-03 SK SK597-96A patent/SK283271B6/sk not_active IP Right Cessation
- 1994-11-03 EP EP95900965A patent/EP0727997B1/en not_active Expired - Lifetime
- 1994-11-03 KR KR1019960702485A patent/KR100345627B1/ko not_active IP Right Cessation
- 1994-11-03 CA CA002176360A patent/CA2176360C/en not_active Expired - Lifetime
- 1994-11-03 US US08/364,953 patent/US5739152A/en not_active Expired - Lifetime
- 1994-11-03 UA UA96051803A patent/UA40633C2/uk unknown
- 1994-11-03 CZ CZ19961338A patent/CZ290772B6/cs not_active IP Right Cessation
- 1994-11-03 RU RU96112112A patent/RU2144358C1/ru active
- 1994-11-09 EG EG71094A patent/EG20764A/xx active
- 1994-11-14 MY MYPI94003029A patent/MY121201A/en unknown
- 1994-11-23 SA SA94150314A patent/SA94150314B1/ar unknown
-
1996
- 1996-05-10 FI FI961999A patent/FI116999B/fi not_active IP Right Cessation
- 1996-05-10 NO NO19961898A patent/NO314877B1/no not_active IP Right Cessation
-
1998
- 1998-12-22 HK HK98114639A patent/HK1013261A1/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4A | Patent expired |
Expiry date: 20141103 |