PL3145508T3 - Nanocząstki klewidypiny i ich kompozycje farmaceutyczne - Google Patents
Nanocząstki klewidypiny i ich kompozycje farmaceutyczneInfo
- Publication number
- PL3145508T3 PL3145508T3 PL15795707.7T PL15795707T PL3145508T3 PL 3145508 T3 PL3145508 T3 PL 3145508T3 PL 15795707 T PL15795707 T PL 15795707T PL 3145508 T3 PL3145508 T3 PL 3145508T3
- Authority
- PL
- Poland
- Prior art keywords
- clevidipine
- nanoparticles
- pharmaceutical compositions
- pharmaceutical
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462000119P | 2014-05-19 | 2014-05-19 | |
PCT/US2015/031470 WO2015179334A1 (en) | 2014-05-19 | 2015-05-19 | Clevidipine nanoparticles and pharmaceutical compositions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3145508T3 true PL3145508T3 (pl) | 2023-10-23 |
Family
ID=54554604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL15795707.7T PL3145508T3 (pl) | 2014-05-19 | 2015-05-19 | Nanocząstki klewidypiny i ich kompozycje farmaceutyczne |
Country Status (10)
Country | Link |
---|---|
US (2) | US11737989B2 (pl) |
EP (1) | EP3145508B1 (pl) |
KR (1) | KR102380701B1 (pl) |
CN (2) | CN106456617A (pl) |
CA (1) | CA2947486C (pl) |
ES (1) | ES2950154T3 (pl) |
MX (1) | MX2016015208A (pl) |
PL (1) | PL3145508T3 (pl) |
RU (1) | RU2759673C2 (pl) |
WO (1) | WO2015179334A1 (pl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105796494B (zh) * | 2016-04-01 | 2019-10-11 | 广东药科大学 | 一种含氨基酸的尼莫地平亚微乳注射液及其制备方法 |
CN105796490B (zh) * | 2016-04-01 | 2019-12-10 | 广东药科大学 | 一种含氨基酸的尼莫地平注射液组合物及其制备方法 |
CN107281104B (zh) * | 2017-05-27 | 2021-02-02 | 济南康和医药科技有限公司 | 一种丁酸氯维地平磷脂复合物脂质体及其制备方法 |
EP3804703A1 (de) * | 2019-10-10 | 2021-04-14 | Bayer AG | Verfahren zur herstellung eines nanopartikulären wirkstoffs |
EP3884930A1 (en) | 2020-03-23 | 2021-09-29 | Bayer AG | Nano-dry-melting |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5453523A (en) * | 1993-06-16 | 1995-09-26 | Emulsion Technology, Inc. | Process for obtaining highly purified phosphatidylcholine |
SE9303657D0 (sv) | 1993-11-05 | 1993-11-05 | Astra Ab | Short-acting dihydropyridines |
SE9303744D0 (sv) | 1993-11-12 | 1993-11-12 | Astra Ab | Pharmaceutical emulsion |
SE9804002D0 (sv) | 1998-11-23 | 1998-11-23 | Astra Ab | New manufacturing process |
AU2007247770B2 (en) * | 2006-05-04 | 2013-07-18 | Reformpharm Pty Ltd | Drug release from nanoparticle-coated capsules |
PL2320740T3 (pl) | 2008-08-01 | 2014-09-30 | The Medicines Co | Kompozycje farmaceutyczne klewidypiny oraz sposoby ich wytwarzania z niskim stężeniem zanieczyszczeń |
US8679344B2 (en) * | 2008-12-17 | 2014-03-25 | Cerion Technology, Inc. | Process for solvent shifting a nanoparticle dispersion |
DE102009008478A1 (de) | 2009-02-11 | 2010-08-19 | PHAST Gesellschaft für pharmazeutische Qualitätsstandards mbH | Vorrichtung und Verfahren zur Herstellung pharmazeutisch hochfeiner Partikel sowie zur Beschichtung solcher Partikel in Mikroreaktoren |
US8852644B2 (en) * | 2010-03-22 | 2014-10-07 | Instillo Gmbh | Method and device for producing microparticles or nanoparticles |
GB201015079D0 (en) | 2010-09-10 | 2010-10-27 | Helperby Therapeutics Ltd | Novel use |
US8658676B2 (en) | 2010-10-12 | 2014-02-25 | The Medicines Company | Clevidipine emulsion formulations containing antimicrobial agents |
HUE026295T2 (en) * | 2010-10-12 | 2016-06-28 | The Medicines Co | Clevidipine emulsion formulations containing antimicrobial agents |
US8691275B2 (en) | 2011-01-28 | 2014-04-08 | Zx Pharma, Llc | Controlled-release melatonin compositions and related methods |
EP2526926A1 (de) | 2011-05-25 | 2012-11-28 | Justus-Liebig-Universität Gießen | Biokompatible Nanopolymerpartikel mit Wirkstoffen für die pulmonale Applikation |
AU2012303683B2 (en) * | 2011-08-26 | 2016-09-08 | Wockhardt Limited | Methods for treating cardiovascular disorders |
US20150246137A1 (en) * | 2012-09-27 | 2015-09-03 | The University Of North Carolina At Chapel Hill | Lipid coated nanoparticles containing agents having low aqueous and lipid solubilities and methods thereof |
EA030354B1 (ru) | 2012-10-26 | 2018-07-31 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Способ уменьшения диспноэ у пациента с острой сердечной недостаточностью |
CN103479577A (zh) * | 2013-09-30 | 2014-01-01 | 山东大学 | 含有丁酸氯维地平的脂质纳米混悬剂及其冻干制剂 |
-
2015
- 2015-05-19 MX MX2016015208A patent/MX2016015208A/es unknown
- 2015-05-19 CN CN201580033837.9A patent/CN106456617A/zh active Pending
- 2015-05-19 RU RU2016149538A patent/RU2759673C2/ru not_active Application Discontinuation
- 2015-05-19 ES ES15795707T patent/ES2950154T3/es active Active
- 2015-05-19 CN CN202210357146.6A patent/CN114668740A/zh active Pending
- 2015-05-19 KR KR1020167032347A patent/KR102380701B1/ko active IP Right Grant
- 2015-05-19 PL PL15795707.7T patent/PL3145508T3/pl unknown
- 2015-05-19 US US15/312,461 patent/US11737989B2/en active Active
- 2015-05-19 CA CA2947486A patent/CA2947486C/en active Active
- 2015-05-19 WO PCT/US2015/031470 patent/WO2015179334A1/en active Application Filing
- 2015-05-19 EP EP15795707.7A patent/EP3145508B1/en active Active
-
2022
- 2022-11-29 US US18/071,110 patent/US20230145206A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3145508A4 (en) | 2018-01-24 |
KR102380701B1 (ko) | 2022-03-31 |
WO2015179334A1 (en) | 2015-11-26 |
US20170087093A1 (en) | 2017-03-30 |
EP3145508A1 (en) | 2017-03-29 |
RU2759673C2 (ru) | 2021-11-16 |
RU2016149538A (ru) | 2018-06-20 |
CN114668740A (zh) | 2022-06-28 |
KR20170032886A (ko) | 2017-03-23 |
CA2947486C (en) | 2023-09-26 |
BR112016027104A2 (pt) | 2018-07-10 |
US20230145206A1 (en) | 2023-05-11 |
US11737989B2 (en) | 2023-08-29 |
EP3145508C0 (en) | 2023-07-05 |
ES2950154T3 (es) | 2023-10-05 |
EP3145508B1 (en) | 2023-07-05 |
RU2016149538A3 (pl) | 2019-01-17 |
MX2016015208A (es) | 2017-03-23 |
CA2947486A1 (en) | 2015-11-26 |
CN106456617A (zh) | 2017-02-22 |
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