DK3166960T3 - Lav-substituerede polymyxiner og sammensætninger deraf - Google Patents

Lav-substituerede polymyxiner og sammensætninger deraf Download PDF

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Publication number
DK3166960T3
DK3166960T3 DK15735887.0T DK15735887T DK3166960T3 DK 3166960 T3 DK3166960 T3 DK 3166960T3 DK 15735887 T DK15735887 T DK 15735887T DK 3166960 T3 DK3166960 T3 DK 3166960T3
Authority
DK
Denmark
Prior art keywords
polymyxines
substituted
compositions
low
substituted polymyxines
Prior art date
Application number
DK15735887.0T
Other languages
English (en)
Inventor
Vidar Bjørnstad
Sølvi Gunnes
Torben Koch
Claes Melander
Original Assignee
Xellia Pharmaceuticals Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xellia Pharmaceuticals Aps filed Critical Xellia Pharmaceuticals Aps
Application granted granted Critical
Publication of DK3166960T3 publication Critical patent/DK3166960T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62Polymyxins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DK15735887.0T 2014-07-09 2015-06-29 Lav-substituerede polymyxiner og sammensætninger deraf DK3166960T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462022399P 2014-07-09 2014-07-09
PCT/EP2015/064764 WO2016005223A1 (en) 2014-07-09 2015-06-29 Low substituted polymyxins and compositions thereof

Publications (1)

Publication Number Publication Date
DK3166960T3 true DK3166960T3 (da) 2019-10-14

Family

ID=53539668

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15735887.0T DK3166960T3 (da) 2014-07-09 2015-06-29 Lav-substituerede polymyxiner og sammensætninger deraf

Country Status (16)

Country Link
US (1) US10711040B2 (da)
EP (1) EP3166960B1 (da)
JP (1) JP2017523953A (da)
KR (1) KR20170032348A (da)
CN (1) CN106661090A (da)
AU (1) AU2015286956A1 (da)
BR (1) BR112017000228A2 (da)
CA (1) CA2949328C (da)
DK (1) DK3166960T3 (da)
EA (1) EA201692569A1 (da)
ES (1) ES2749053T3 (da)
HU (1) HUE046814T2 (da)
IL (1) IL249695A0 (da)
PT (1) PT3166960T (da)
SI (1) SI3166960T1 (da)
WO (1) WO2016005223A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA027067B1 (ru) 2013-01-11 2017-06-30 Кселлия Фармасьютикалз Апс Полимиксины, композиции, способы получения и способы применения
RS60874B1 (sr) 2014-10-03 2020-11-30 Xellia Pharmaceuticals Aps Kompozicije
KR102494511B1 (ko) 2014-10-03 2023-01-31 셀리아 파마슈티칼즈 에이피에스 흡입 장치
CN110845579B (zh) * 2019-08-08 2022-04-19 上海市食品药品检验研究院 一种多黏菌素e组分及其光化学产物和液相色谱-质谱分析方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1062895A (en) 1962-12-13 1967-03-22 Wellcome Found Sulphomethyl derivatives of polymxin
FR1586834A (da) 1968-02-12 1970-03-06
DE1906699A1 (de) 1968-02-12 1970-02-05 Pfizer Neue Polymyxinderivate und Verfahren zu deren Herstellung
AU611030B2 (en) 1988-04-07 1991-05-30 Edward Shanbrom Non-thrombogenic intravascular time release catheter
WO1998020836A2 (en) 1996-11-15 1998-05-22 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
US5767068A (en) * 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
CA2447600C (en) 2001-05-18 2015-10-20 Chiron Corporation Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics
US20040022740A1 (en) 2001-07-10 2004-02-05 Baker William R. Macrolide formulations for inhalation and methods of treatment of endobronchial infections
DE60217060T2 (de) 2002-03-01 2007-06-21 Chiesi Farmaceutici S.P.A. Pharmazeutische Zusammensetzungen, die Lungensurfactants und ein Polymyxin umfassen und verbesserte Oberflächenspannung-senkende Eigenschaften haben
WO2008025560A1 (en) 2006-09-01 2008-03-06 Pari Pharma Gmbh Methods for taste masking of nebulised compositions for nasal and pulmonary inhalation therapy
US20080066739A1 (en) 2006-09-20 2008-03-20 Lemahieu Edward Methods and systems of delivering medication via inhalation
PL2470555T3 (pl) 2009-10-30 2015-05-29 Xellia Pharmaceuticals Aps Sposób oczyszczania kolistyny i oczyszczone składniki kolistyny
WO2012168820A1 (en) 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
EA027067B1 (ru) * 2013-01-11 2017-06-30 Кселлия Фармасьютикалз Апс Полимиксины, композиции, способы получения и способы применения
TW201522364A (zh) 2013-06-07 2015-06-16 Xellia Pharmaceuticals Aps 黏菌素甲磺酸鈉(cms)之定性方法
RS60874B1 (sr) 2014-10-03 2020-11-30 Xellia Pharmaceuticals Aps Kompozicije

Also Published As

Publication number Publication date
KR20170032348A (ko) 2017-03-22
IL249695A0 (en) 2017-02-28
AU2015286956A1 (en) 2016-12-08
CA2949328C (en) 2023-01-31
PT3166960T (pt) 2019-10-25
SI3166960T1 (sl) 2019-12-31
CN106661090A (zh) 2017-05-10
JP2017523953A (ja) 2017-08-24
US20170218024A1 (en) 2017-08-03
BR112017000228A2 (pt) 2017-10-31
EP3166960B1 (en) 2019-08-07
CA2949328A1 (en) 2016-01-14
US10711040B2 (en) 2020-07-14
EA201692569A1 (ru) 2017-05-31
EP3166960A1 (en) 2017-05-17
ES2749053T3 (es) 2020-03-18
WO2016005223A1 (en) 2016-01-14
HUE046814T2 (hu) 2020-03-30

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