FI115034B - Menetelmä uudelleenkiteytymättömän estradiolia sisältävän laastarin valmistamiseksi - Google Patents

Menetelmä uudelleenkiteytymättömän estradiolia sisältävän laastarin valmistamiseksi Download PDF

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Publication number
FI115034B
FI115034B FI955259A FI955259A FI115034B FI 115034 B FI115034 B FI 115034B FI 955259 A FI955259 A FI 955259A FI 955259 A FI955259 A FI 955259A FI 115034 B FI115034 B FI 115034B
Authority
FI
Finland
Prior art keywords
estradiol
weight
added
esters
process according
Prior art date
Application number
FI955259A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI955259A (fi
FI955259A0 (fi
Inventor
Michael Horstmann
Reinhold Meconi
Frank Seibertz
Rainer Lichtenberger
Original Assignee
Merck Patent Gmbh
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh, Lohmann Therapie Syst Lts filed Critical Merck Patent Gmbh
Publication of FI955259A0 publication Critical patent/FI955259A0/fi
Publication of FI955259A publication Critical patent/FI955259A/fi
Application granted granted Critical
Publication of FI115034B publication Critical patent/FI115034B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI955259A 1993-05-06 1995-11-02 Menetelmä uudelleenkiteytymättömän estradiolia sisältävän laastarin valmistamiseksi FI115034B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE4314970 1993-05-06
DE4314970 1993-05-06
DE4336557 1993-10-27
DE4336557A DE4336557C2 (de) 1993-05-06 1993-10-27 Estradiolhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung
PCT/EP1994/001279 WO1994026257A1 (de) 1993-05-06 1994-04-25 Estradiolhaltiges transdermales therapeutisches system
EP9401279 1994-04-25

Publications (3)

Publication Number Publication Date
FI955259A0 FI955259A0 (fi) 1995-11-02
FI955259A FI955259A (fi) 1995-11-30
FI115034B true FI115034B (fi) 2005-02-28

Family

ID=25925640

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955259A FI115034B (fi) 1993-05-06 1995-11-02 Menetelmä uudelleenkiteytymättömän estradiolia sisältävän laastarin valmistamiseksi

Country Status (28)

Country Link
US (2) US6143319A (no)
EP (1) EP0697860B1 (no)
JP (1) JP3885233B2 (no)
KR (1) KR100343877B1 (no)
CN (1) CN1136843C (no)
AT (1) ATE196843T1 (no)
AU (1) AU696816B2 (no)
CA (1) CA2160775C (no)
CZ (1) CZ291656B6 (no)
DE (2) DE4336557C2 (no)
DK (1) DK0697860T3 (no)
ES (1) ES2152979T3 (no)
FI (1) FI115034B (no)
GR (1) GR3035200T3 (no)
HU (1) HU221166B1 (no)
IL (1) IL109508A (no)
MX (1) MXPA94003365A (no)
MY (1) MY111515A (no)
NO (1) NO309891B1 (no)
NZ (1) NZ266140A (no)
PL (1) PL179962B1 (no)
PT (1) PT697860E (no)
RU (1) RU2140784C1 (no)
SI (1) SI0697860T1 (no)
SK (1) SK282230B6 (no)
TW (1) TW382599B (no)
UA (1) UA29476C2 (no)
WO (1) WO1994026257A1 (no)

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ES2226203T3 (es) 1998-12-23 2005-03-16 Idea Ag Formulacion mejorada para aplicacion topica no invasiva.
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Also Published As

Publication number Publication date
JP3885233B2 (ja) 2007-02-21
IL109508A (en) 1998-10-30
SI0697860T1 (en) 2001-02-28
TW382599B (en) 2000-02-21
CA2160775A1 (en) 1994-11-24
CA2160775C (en) 2006-06-06
IL109508A0 (en) 1994-08-26
AU6721394A (en) 1994-12-12
PL311590A1 (en) 1996-02-19
DK0697860T3 (da) 2001-02-05
JPH08509748A (ja) 1996-10-15
AU696816B2 (en) 1998-09-17
ES2152979T3 (es) 2001-02-16
NZ266140A (en) 1997-09-22
US6143319A (en) 2000-11-07
HUT73847A (en) 1996-09-30
HU9503168D0 (en) 1996-01-29
SK282230B6 (sk) 2001-12-03
FI955259A (fi) 1995-11-30
WO1994026257A1 (de) 1994-11-24
DE59409548D1 (de) 2000-11-16
FI955259A0 (fi) 1995-11-02
DE4336557A1 (de) 1994-11-10
NO954413L (no) 1995-11-03
US6521250B2 (en) 2003-02-18
PT697860E (pt) 2001-03-30
MY111515A (en) 2000-07-31
RU2140784C1 (ru) 1999-11-10
CN1122569A (zh) 1996-05-15
CN1136843C (zh) 2004-02-04
SK137995A3 (en) 1997-02-05
ATE196843T1 (de) 2000-10-15
EP0697860B1 (de) 2000-10-11
EP0697860A1 (de) 1996-02-28
DE4336557C2 (de) 1997-07-17
PL179962B1 (pl) 2000-11-30
GR3035200T3 (en) 2001-04-30
KR100343877B1 (ko) 2002-12-05
US20020012691A1 (en) 2002-01-31
UA29476C2 (uk) 2000-11-15
NO954413D0 (no) 1995-11-03
CZ289295A3 (en) 1996-08-14
CZ291656B6 (cs) 2003-04-16
NO309891B1 (no) 2001-04-17
HU221166B1 (en) 2002-08-28
KR960702300A (ko) 1996-04-27
MXPA94003365A (es) 2005-03-09

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