FI109336B - Järjestelmä ja menetelmä biologisten nesteiden käsittelemiseksi - Google Patents
Järjestelmä ja menetelmä biologisten nesteiden käsittelemiseksi Download PDFInfo
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- FI109336B FI109336B FI932031A FI932031A FI109336B FI 109336 B FI109336 B FI 109336B FI 932031 A FI932031 A FI 932031A FI 932031 A FI932031 A FI 932031A FI 109336 B FI109336 B FI 109336B
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Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
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- Pharmacology & Pharmacy (AREA)
- Pathology (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60965490 | 1990-11-06 | ||
| US07/609,654 US5100564A (en) | 1990-11-06 | 1990-11-06 | Blood collection and processing system |
| PCT/US1991/008316 WO1992007656A2 (en) | 1990-11-06 | 1991-11-06 | System and method for processing biological fluids |
| US9108316 | 1991-11-06 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI932031A0 FI932031A0 (fi) | 1993-05-05 |
| FI932031A FI932031A (fi) | 1993-05-05 |
| FI109336B true FI109336B (fi) | 2002-07-15 |
Family
ID=24441729
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI932031A FI109336B (fi) | 1990-11-06 | 1993-05-05 | Järjestelmä ja menetelmä biologisten nesteiden käsittelemiseksi |
| FI20020342A FI116366B (fi) | 1990-11-06 | 2002-02-20 | Menetelmä biologisen juoksevan väliaineen käsittelemiseksi |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20020342A FI116366B (fi) | 1990-11-06 | 2002-02-20 | Menetelmä biologisen juoksevan väliaineen käsittelemiseksi |
Country Status (19)
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| EP (3) | EP1038541A3 (es) |
| JP (1) | JP2570906B2 (es) |
| KR (1) | KR100193172B1 (es) |
| CN (2) | CN1028964C (es) |
| AT (1) | AT404674B (es) |
| AU (2) | AU651646B2 (es) |
| CA (1) | CA2095623C (es) |
| DE (2) | DE4192629T1 (es) |
| DK (1) | DK175916B1 (es) |
| ES (1) | ES2153827T3 (es) |
| FI (2) | FI109336B (es) |
| GB (3) | GB2277464B (es) |
| MX (1) | MX9101962A (es) |
| NL (1) | NL194639C (es) |
| NZ (1) | NZ240489A (es) |
| SE (2) | SE514255C2 (es) |
| WO (1) | WO1992007656A2 (es) |
| ZA (1) | ZA918788B (es) |
Families Citing this family (176)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5344561A (en) * | 1989-05-09 | 1994-09-06 | Pall Corporation | Device for depletion of the leucocyte content of blood and blood components |
| US5258126A (en) * | 1989-09-12 | 1993-11-02 | Pall Corporation | Method for obtaining platelets |
| US5316674A (en) * | 1989-09-12 | 1994-05-31 | Pall Corporation | Device for processing blood for human transfusion |
| US5152905A (en) * | 1989-09-12 | 1992-10-06 | Pall Corporation | Method for processing blood for human transfusion |
| US5360545A (en) * | 1989-09-12 | 1994-11-01 | Pall Corporation | Filter for obtaining platelets |
| US5266219A (en) * | 1989-12-28 | 1993-11-30 | Pall Corporation | Device and method for separating plasma from blood |
| US5863436A (en) * | 1990-05-24 | 1999-01-26 | Pall Corporation | Venting system |
| US5126054A (en) * | 1990-05-24 | 1992-06-30 | Pall Corporation | Venting means |
| US5302299A (en) * | 1990-05-24 | 1994-04-12 | Pall Corporation | Biological semi-fluid processing assembly |
| US5362406A (en) * | 1990-07-27 | 1994-11-08 | Pall Corporation | Leucocyte depleting filter device and method of use |
| US5217627A (en) * | 1990-11-06 | 1993-06-08 | Pall Corporation | System and method for processing biological fluid |
| US5935092A (en) | 1990-12-20 | 1999-08-10 | Baxter International Inc. | Systems and methods for removing free and entrained contaminants in plasma |
| US5498336A (en) * | 1991-02-22 | 1996-03-12 | Terumo Kabushiki Kaisha | Leukocyte-removing filter and leukocyte-removing apparatus furnished therewith |
| US5672481A (en) * | 1991-10-23 | 1997-09-30 | Cellpro, Incorporated | Apparatus and method for particle separation in a closed field |
| CA2074671A1 (en) * | 1991-11-04 | 1993-05-05 | Thomas Bormann | Device and method for separating plasma from a biological fluid |
| CA2072378C (en) * | 1991-11-21 | 2000-12-26 | Vlado Ivan Matkovich | System for processing separate containers of biological fluid |
| US5804079A (en) | 1991-12-23 | 1998-09-08 | Baxter International Inc. | Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes |
| US5549834A (en) | 1991-12-23 | 1996-08-27 | Baxter International Inc. | Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes |
| AU4107396A (en) | 1992-03-02 | 1996-06-06 | Cerus Corporation | Synthetic media for blood components |
| GR930100237A (el) * | 1992-06-10 | 1994-02-28 | Pall Corp | Σύστημα δια την επεξεργασίαν υλικού ζώνης μεταπτώσεως. |
| CA2083075A1 (en) * | 1992-06-10 | 1993-12-11 | Vlado I. Matkovich | System for treating transition zone material |
| WO1994001193A1 (en) * | 1992-07-13 | 1994-01-20 | Pall Corporation | Automated system and method for processing biological fluid |
| JPH07509153A (ja) | 1992-07-13 | 1995-10-12 | ポール・コーポレーション | 生物学的流体を処理するための自動化されたシステムおよび方法 |
| GB9218581D0 (en) * | 1992-09-02 | 1992-10-14 | Pall Corp | Removal of unwanted fluids from processed blood products |
| DE69324754T2 (de) * | 1992-10-07 | 2000-01-13 | Asahi Medical Co. Ltd., Tokio/Tokyo | Filter und System zur Trennung der Leukozyten |
| WO1994009836A2 (en) * | 1992-11-03 | 1994-05-11 | Chronomed, Inc. | Methods and procedures for preparing red blood fractions |
| US5316681A (en) * | 1992-11-06 | 1994-05-31 | Baxter International Inc. | Method of filtering body fluid using a rinse chamber bag |
| JP3246620B2 (ja) * | 1993-02-22 | 2002-01-15 | 旭メディカル株式会社 | 白血球除去フィルター支持体 |
| US5547591A (en) * | 1993-06-01 | 1996-08-20 | Asahi Medical Co., Ltd. | Method for separating a blood material into blood components by centrifugation, and centrifugal apparatus |
| GB9311988D0 (en) * | 1993-06-10 | 1993-07-28 | Pall Corp | Device and method for separating plasma from a blood product |
| EP0662857B1 (en) * | 1993-07-26 | 1999-04-07 | Baxter International Inc. | Systems and methods for reducing leukocytes in cellular products |
| FR2712825B1 (fr) * | 1993-11-23 | 1996-02-23 | Jouan | Procédé de traitement par centrifugation d'un liquide conditionné dans des poches à parois souples, reliées à au moins un filtre. |
| US5545339A (en) * | 1994-02-25 | 1996-08-13 | Pall Corporation | Method for processing biological fluid and treating separated component |
| US5591350A (en) * | 1994-04-15 | 1997-01-07 | Pall Corporation | Iodine disinfection method using a gaseous iodine treated porous medium |
| US5547108A (en) * | 1994-08-02 | 1996-08-20 | Pall Corporation | Expressor |
| US6306454B1 (en) * | 1994-10-17 | 2001-10-23 | Baxter International Inc. | Method for producing improved medical devices and devices so produced |
| US5972217A (en) * | 1994-10-17 | 1999-10-26 | Baxter International Inc. | Blood cell separation devices having a membrane with particular coating |
| US6746482B2 (en) | 1994-10-17 | 2004-06-08 | Baxter International Inc. | Method for producing medical devices and devices so produced |
| US6045701A (en) * | 1994-10-17 | 2000-04-04 | Baxter International Inc. | Method of filtering a fluid suspension with a membrane having a particular coating |
| US5647985A (en) * | 1994-10-17 | 1997-07-15 | Baxter International Inc. | Whole blood leukodepletion and platelet filter |
| US5660731A (en) * | 1994-11-08 | 1997-08-26 | Pall Corporation | Filter for separating photoactive agent |
| US7169547B2 (en) | 1994-12-05 | 2007-01-30 | New York Blood Center, Inc. | High concentration white blood cells as a therapeutic product |
| US5585007A (en) * | 1994-12-07 | 1996-12-17 | Plasmaseal Corporation | Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant |
| US5728306A (en) * | 1994-12-23 | 1998-03-17 | Baxter International Inc. | Leukodepletion filter and method for filtering leukocytes from freshly drawn blood |
| US5630946A (en) * | 1995-02-15 | 1997-05-20 | Pall Corporation | Method for processing a biological fluid including leukocyte removal in an extracorporeal circuit |
| EP0824380B1 (en) * | 1995-04-18 | 2002-01-09 | Gambro, Inc., | Particle separation method |
| US6053856A (en) * | 1995-04-18 | 2000-04-25 | Cobe Laboratories | Tubing set apparatus and method for separation of fluid components |
| US5951877A (en) * | 1995-04-18 | 1999-09-14 | Cobe Laboratories, Inc. | Particle filter method |
| US5721024A (en) * | 1995-06-07 | 1998-02-24 | Pall Corporation | Material for flexible medical products |
| US6544727B1 (en) | 1995-06-07 | 2003-04-08 | Cerus Corporation | Methods and devices for the removal of psoralens from blood products |
| US5759413A (en) * | 1995-06-07 | 1998-06-02 | Baxter International Inc. | Systems and method for estimating platelet counts using a spleen mobilization function |
| US6140040A (en) * | 1995-10-06 | 2000-10-31 | Advanced Minerals Corporation | Method of mechanically separating microparticles suspended in fluids using particulate media |
| US5865785A (en) * | 1996-02-23 | 1999-02-02 | Baxter International Inc. | Systems and methods for on line finishing of cellular blood products like platelets harvested for therapeutic purposes |
| US20020115585A1 (en) * | 1996-06-07 | 2002-08-22 | Hei Derek J. | Method and devices for the removal of psoralens from blood products |
| US6190855B1 (en) * | 1996-10-28 | 2001-02-20 | Baxter International Inc. | Systems and methods for removing viral agents from blood |
| US6168718B1 (en) | 1996-11-08 | 2001-01-02 | Pall Corporation | Method for purifying blood plasma and apparatus suitable therefor |
| WO1998028057A1 (en) * | 1996-12-24 | 1998-07-02 | Pall Corporation | Biological fluid processing |
| US20010009756A1 (en) | 1998-01-06 | 2001-07-26 | Derek Hei | Flow devices for the reduction of compounds from biological compositions and methods of use |
| US20010018179A1 (en) | 1998-01-06 | 2001-08-30 | Derek J. Hei | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use |
| US5954971A (en) * | 1997-01-07 | 1999-09-21 | Haemonetics Corporation | Pumped-filter blood-processing apparatus and methods |
| DE19712298C2 (de) | 1997-03-24 | 1999-05-20 | Fresenius Ag | Vorrichtung und Verfahren zum Trennen von Blut in Blutkomponenten |
| US7611831B2 (en) * | 1998-01-06 | 2009-11-03 | Cerus Corporation | Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix |
| US6051146A (en) * | 1998-01-20 | 2000-04-18 | Cobe Laboratories, Inc. | Methods for separation of particles |
| US6497823B1 (en) * | 1998-01-23 | 2002-12-24 | Pall Corporation | Method for processing a biological fluid |
| US6669905B1 (en) * | 1998-05-21 | 2003-12-30 | Baxter International Inc. | Systems and methods for collecting plasma that is free or virtually free of cellular blood species |
| FR2781681B1 (fr) * | 1998-07-31 | 2000-11-24 | Maco Pharma Sa | Ensemble de poches en circuit clos, destine a recueillir, separer et purifier differents constituants du sang a partir d'un prelevement de sang total |
| US6153113A (en) | 1999-02-22 | 2000-11-28 | Cobe Laboratories, Inc. | Method for using ligands in particle separation |
| US6945411B1 (en) | 1999-03-16 | 2005-09-20 | Pall Corporation | Biological fluid filter and system |
| US6334842B1 (en) | 1999-03-16 | 2002-01-01 | Gambro, Inc. | Centrifugal separation apparatus and method for separating fluid components |
| GB9909630D0 (en) | 1999-04-28 | 1999-06-23 | Zeneca Ltd | Reactor |
| EP1057534A1 (en) | 1999-06-03 | 2000-12-06 | Haemonetics Corporation | Centrifugation bowl with filter core |
| US6629919B2 (en) | 1999-06-03 | 2003-10-07 | Haemonetics Corporation | Core for blood processing apparatus |
| CA2373689A1 (en) * | 1999-07-29 | 2001-02-08 | Thomas W. Coneys | Sampling tube holder for blood sampling system |
| US6524231B1 (en) * | 1999-09-03 | 2003-02-25 | Baxter International Inc. | Blood separation chamber with constricted interior channel and recessed passage |
| US6875191B2 (en) * | 1999-09-03 | 2005-04-05 | Baxter International Inc. | Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter |
| JP2001071353A (ja) * | 1999-09-06 | 2001-03-21 | Tokuyama Sekisui Ind Corp | 血液回路用フィルタハウジングの射出成形方法 |
| US7651474B2 (en) | 1999-10-01 | 2010-01-26 | Caridianbct, Inc. | Method and apparatus for leukoreduction of red blood cells |
| US7686779B1 (en) | 1999-10-01 | 2010-03-30 | Caridian BCT, Inc | Extracorporeal blood processing methods and apparatus |
| US6354986B1 (en) | 2000-02-16 | 2002-03-12 | Gambro, Inc. | Reverse-flow chamber purging during centrifugal separation |
| US6723238B2 (en) * | 2000-09-20 | 2004-04-20 | Kendro Laboratory Products, L.P. | Blood centrifuge cup having a replaceable compartment for filter support |
| ATE530212T1 (de) * | 2001-04-26 | 2011-11-15 | Asahi Kasei Medical Co Ltd | Blutfiltrationsmethode |
| FR2827176B1 (fr) * | 2001-07-12 | 2003-12-19 | Biolog | Procede de fiabilisation de la tracabilite des prelevements sanguins lors des operations d'extraction notamment du plasma et des globules rouges |
| US7264608B2 (en) * | 2001-12-05 | 2007-09-04 | Fenwal, Inc. | Manual processing systems and methods for providing blood components conditioned for pathogen inactivation |
| EP2208502B1 (en) * | 2001-12-10 | 2019-05-08 | Terumo BCT, Inc. | Disposable assembly for an apheresis system |
| US20030173274A1 (en) * | 2002-02-01 | 2003-09-18 | Frank Corbin | Blood component separation device, system, and method including filtration |
| AU2003223645A1 (en) * | 2002-04-16 | 2003-11-03 | Gambro, Inc. | Blood component processing system, apparatus and method |
| US7374678B2 (en) * | 2002-05-24 | 2008-05-20 | Biomet Biologics, Inc. | Apparatus and method for separating and concentrating fluids containing multiple components |
| US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
| US20030205538A1 (en) | 2002-05-03 | 2003-11-06 | Randel Dorian | Methods and apparatus for isolating platelets from blood |
| US7992725B2 (en) | 2002-05-03 | 2011-08-09 | Biomet Biologics, Llc | Buoy suspension fractionation system |
| US7845499B2 (en) | 2002-05-24 | 2010-12-07 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| AU2003249642A1 (en) * | 2002-05-24 | 2003-12-12 | Biomet Manufacturing Corp. | Apparatus and method for separating and concentrating fluids containing multiple components |
| US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
| ITTO20020736A1 (it) * | 2002-08-21 | 2004-02-22 | Fresenius Hemocare Italia Srl | Filtro per leucociti e suo impiego per l'impoverimento di prodotti del sangue da leucociti. |
| ITTO20020820A1 (it) * | 2002-09-20 | 2004-03-21 | Fresenius Hemocare Italia S R L | Dispositivo e procedimento per separare il sangue in componenti del sangue impoveriti di leucociti. |
| US7297272B2 (en) * | 2002-10-24 | 2007-11-20 | Fenwal, Inc. | Separation apparatus and method |
| US20060054557A1 (en) * | 2002-12-12 | 2006-03-16 | Takahiro Hori | Virus-removing bag and virus-removing method using the same |
| EP1635638A1 (en) | 2003-06-20 | 2006-03-22 | Pall Corporation | Processing of platelet-containing biological fluids |
| US20050124073A1 (en) | 2003-12-09 | 2005-06-09 | Entire Interest | Fat collection and preparation system and method |
| US20050137517A1 (en) * | 2003-12-19 | 2005-06-23 | Baxter International Inc. | Processing systems and methods for providing leukocyte-reduced blood components conditioned for pathogen inactivation |
| US20050208501A1 (en) | 2004-03-16 | 2005-09-22 | Ambion, Inc. | Process and reagents for extraction of RNA from fractionated blood leukocytes |
| WO2006009650A1 (en) * | 2004-06-22 | 2006-01-26 | Gambro, Inc. | Bag assembly for the separation of a composite liquid and method for manufacturing it |
| US7866485B2 (en) | 2005-02-07 | 2011-01-11 | Hanuman, Llc | Apparatus and method for preparing platelet rich plasma and concentrates thereof |
| WO2006086201A2 (en) * | 2005-02-07 | 2006-08-17 | Hanuman Llc | Platelet rich plasma concentrate apparatus and method |
| EP2666494B1 (en) * | 2005-02-07 | 2018-01-17 | Hanuman LLC | Platelet rich plasma concentrate apparatus and method |
| CA2620230A1 (en) * | 2005-10-05 | 2007-04-12 | Gambro Bct, Inc. | Method and apparatus for leukoreduction of red blood cells |
| DE202005015644U1 (de) * | 2005-10-06 | 2007-02-15 | Andreas Hettich Gmbh & Co. Kg | Zentrifugenbecher mit Halterung für Blutbeutel |
| US8979770B2 (en) * | 2006-02-24 | 2015-03-17 | Merck Sharp & Dohme Corp. | Extraction and diagnostic fluid devices, systems and methods of use |
| US8567609B2 (en) | 2006-05-25 | 2013-10-29 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US8430813B2 (en) * | 2006-05-26 | 2013-04-30 | Depuy Spine, Inc. | Illuminated surgical access system including a surgical access device and integrated light emitter |
| US20080147240A1 (en) * | 2006-12-19 | 2008-06-19 | Gambro Bct Inc. | Apparatus for separating a composite liquid with process control on a centrifuge rotor |
| US20080156728A1 (en) * | 2006-12-29 | 2008-07-03 | Bryan Blickhan | Biological fluid filtration systems and methods |
| EP2570129A3 (en) * | 2007-03-07 | 2013-04-17 | JMS Co., Ltd. | Serum preparation apparatus |
| EP2134386B1 (en) * | 2007-04-06 | 2018-12-26 | Fenwal, Inc. | Biological fluid filtration systems and methods |
| US8328024B2 (en) | 2007-04-12 | 2012-12-11 | Hanuman, Llc | Buoy suspension fractionation system |
| JP5479319B2 (ja) | 2007-04-12 | 2014-04-23 | バイオメット・バイオロジックス・リミテッド・ライアビリティ・カンパニー | ブイ式懸濁液分画システム |
| CA2789592C (en) * | 2007-08-31 | 2015-05-12 | The Regents Of The University Of Michigan | Selective cytopheresis devices and related methods thereof |
| WO2009096855A1 (en) * | 2008-01-28 | 2009-08-06 | Milux Holding Sa | Blood clot removal device, system, and method |
| US8075468B2 (en) * | 2008-02-27 | 2011-12-13 | Fenwal, Inc. | Systems and methods for mid-processing calculation of blood composition |
| US8685258B2 (en) * | 2008-02-27 | 2014-04-01 | Fenwal, Inc. | Systems and methods for conveying multiple blood components to a recipient |
| EP2259774B1 (en) | 2008-02-27 | 2012-12-12 | Biomet Biologics, LLC | Methods and compositions for delivering interleukin-1 receptor antagonist |
| US8337711B2 (en) * | 2008-02-29 | 2012-12-25 | Biomet Biologics, Llc | System and process for separating a material |
| US8628489B2 (en) | 2008-04-14 | 2014-01-14 | Haemonetics Corporation | Three-line apheresis system and method |
| US8454548B2 (en) | 2008-04-14 | 2013-06-04 | Haemonetics Corporation | System and method for plasma reduced platelet collection |
| US8702637B2 (en) | 2008-04-14 | 2014-04-22 | Haemonetics Corporation | System and method for optimized apheresis draw and return |
| JP5229665B2 (ja) * | 2008-05-13 | 2013-07-03 | 学校法人立命館 | 血漿又は血清分離方法、及び血漿又は血清分離装置 |
| US8012077B2 (en) * | 2008-05-23 | 2011-09-06 | Biomet Biologics, Llc | Blood separating device |
| FR2934489B1 (fr) * | 2008-07-31 | 2011-11-11 | Imv Technologies | Sachet de conditionnement d'une substance biologique comportant des ouvertures de suspension a un dispositif de support, et bande formee de tels sachets. |
| US8187475B2 (en) | 2009-03-06 | 2012-05-29 | Biomet Biologics, Llc | Method and apparatus for producing autologous thrombin |
| US8834402B2 (en) | 2009-03-12 | 2014-09-16 | Haemonetics Corporation | System and method for the re-anticoagulation of platelet rich plasma |
| US8313954B2 (en) | 2009-04-03 | 2012-11-20 | Biomet Biologics, Llc | All-in-one means of separating blood components |
| US9011800B2 (en) * | 2009-07-16 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for separating biological materials |
| US8875893B2 (en) * | 2010-02-05 | 2014-11-04 | Fenwal, Inc. | Medical containers for use in blood collection and processing and medical systems, methods and apparatus for use in blood collection and processing |
| US8591391B2 (en) | 2010-04-12 | 2013-11-26 | Biomet Biologics, Llc | Method and apparatus for separating a material |
| JP2014500735A (ja) | 2010-10-15 | 2014-01-16 | サイトフェリックス インコーポレイテッド | サイトフェレーシスカートリッジおよびその使用 |
| US8808978B2 (en) | 2010-11-05 | 2014-08-19 | Haemonetics Corporation | System and method for automated platelet wash |
| JP5785713B2 (ja) * | 2010-12-28 | 2015-09-30 | ファミリーセルバンク株式会社 | 白血球分画回収装置 |
| US9302042B2 (en) | 2010-12-30 | 2016-04-05 | Haemonetics Corporation | System and method for collecting platelets and anticipating plasma return |
| US11386993B2 (en) | 2011-05-18 | 2022-07-12 | Fenwal, Inc. | Plasma collection with remote programming |
| JP2015504318A (ja) | 2011-10-14 | 2015-02-12 | サイトフェリックス インコーポレイテッド | 心筋機能を向上させるためのカートリッジおよび方法 |
| US9421317B2 (en) * | 2012-06-08 | 2016-08-23 | Pall Corporation | Cell harvesting device and system |
| US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| EP4029586A1 (en) | 2012-12-03 | 2022-07-20 | EMD Millipore Corporation | Methods and devices used for redundant sterile filtration |
| WO2014127122A1 (en) | 2013-02-18 | 2014-08-21 | Terumo Bct, Inc. | System for blood separation with a separation chamber having an internal gravity valve |
| US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
| US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
| US20140271589A1 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
| US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
| US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
| US9943639B2 (en) * | 2013-10-28 | 2018-04-17 | Boston Scientific Scimed, Inc. | Fluid management system and methods |
| EP3081241A4 (en) * | 2013-12-13 | 2016-12-21 | Asahi Kasei Medical Co Ltd | FILTER MATERIAL FOR LEUKOCYTE REMOVAL AND PROCESS FOR LEUKOCYTE REMOVAL |
| US10159778B2 (en) | 2014-03-24 | 2018-12-25 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
| US9782707B2 (en) | 2014-03-24 | 2017-10-10 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
| US9796166B2 (en) | 2014-03-24 | 2017-10-24 | Fenwal, Inc. | Flexible biological fluid filters |
| US9968738B2 (en) | 2014-03-24 | 2018-05-15 | Fenwal, Inc. | Biological fluid filters with molded frame and methods for making such filters |
| US10376627B2 (en) | 2014-03-24 | 2019-08-13 | Fenwal, Inc. | Flexible biological fluid filters |
| CA2951398C (en) * | 2014-06-24 | 2021-06-08 | Parker-Hannifin Corporation | Multiple identification point automated parameter assurance method |
| US10512888B2 (en) | 2014-06-24 | 2019-12-24 | Parker-Hannifin Corporation | Multiple identification point automated parameter assurance method |
| US9713810B2 (en) | 2015-03-30 | 2017-07-25 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
| US10675394B2 (en) * | 2015-05-07 | 2020-06-09 | Aenitis Technologies | Multiple fluid bag system |
| WO2016177832A1 (en) * | 2015-05-07 | 2016-11-10 | Aenitis Technologies | Closed disposable multiple sterile blood bag system for fractionating blood with the corresponding method |
| US9757721B2 (en) | 2015-05-11 | 2017-09-12 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
| CN105641988B (zh) * | 2015-12-02 | 2018-01-30 | 重庆浪尖渝力科技有限公司 | 生物样品混悬液自动分离设备的挂板组件 |
| FR3055557B1 (fr) | 2016-09-08 | 2018-10-12 | Maco Pharma Sa | Unite de filtration comprenant un bord peripherique courbe |
| FR3055556B1 (fr) | 2016-09-08 | 2018-10-12 | Maco Pharma | Unite de filtration comprenant des portions en dome |
| FR3047184A1 (fr) | 2016-10-03 | 2017-08-04 | Biolog | Dispositif de stockage d'elements |
| US10792416B2 (en) | 2017-05-30 | 2020-10-06 | Haemonetics Corporation | System and method for collecting plasma |
| US10758652B2 (en) | 2017-05-30 | 2020-09-01 | Haemonetics Corporation | System and method for collecting plasma |
| US11065376B2 (en) | 2018-03-26 | 2021-07-20 | Haemonetics Corporation | Plasmapheresis centrifuge bowl |
| PL3621674T3 (pl) | 2018-05-21 | 2022-01-31 | Fenwal, Inc. | Systemy do optymalizacji pobieranych objętości osocza |
| US12033750B2 (en) | 2018-05-21 | 2024-07-09 | Fenwal, Inc. | Plasma collection |
| US11412967B2 (en) | 2018-05-21 | 2022-08-16 | Fenwal, Inc. | Systems and methods for plasma collection |
| US11148083B2 (en) | 2019-12-27 | 2021-10-19 | Pall Corporation | Method and system for recovering fluid |
| US11498023B2 (en) | 2019-12-27 | 2022-11-15 | Pall Corporation | Method and system for recovering fluid |
| FR3132209A1 (fr) | 2022-02-03 | 2023-08-04 | Cellquest | Bioréacteur pour la production d’un médicament biologique et support pour un tel bioréacteur |
| CN114504012B (zh) * | 2022-02-23 | 2023-06-27 | 李�真 | 一种畜禽屠宰的机体主动脉放血集血方法 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US492362A (en) | 1893-02-21 | Alois opiioven | ||
| US3800947A (en) * | 1971-07-16 | 1974-04-02 | P Smith | Reagent tube and centrifugally operated solid-liquid separating device |
| US4111199A (en) * | 1977-03-31 | 1978-09-05 | Isaac Djerassi | Method of collecting transfusable granulocytes by gravity leukopheresis |
| GB2018151B (en) * | 1978-03-06 | 1982-12-08 | Asahi Chemical Ind | Seperation of leukocytes from leukocyte-containing suspension by filtration |
| EP0026417B1 (de) * | 1979-09-22 | 1983-12-14 | Firma Andreas Hettich | Zentrifuge mit Blutbeutelsystem zur Trennung von Blutkomponenten |
| JPS603367B2 (ja) * | 1979-10-09 | 1985-01-28 | 旭化成株式会社 | 白血球分離法および白血球分離材 |
| US4322298A (en) * | 1981-06-01 | 1982-03-30 | Advanced Blood Component Technology, Inc. | Centrifugal cell separator, and method of use thereof |
| US4416778A (en) * | 1981-10-20 | 1983-11-22 | Neocyte, Inc. | Means for preparing neocyte enriched blood |
| US4543084A (en) * | 1982-02-09 | 1985-09-24 | Bailey Mary L | Blood bag support for centrifugation |
| US4919823A (en) * | 1982-06-04 | 1990-04-24 | Miles Inc. | Blood bag system with integral filtering means |
| US4767541A (en) * | 1982-06-04 | 1988-08-30 | Miles Laboratories, Inc. | Method of removing platelets and white cells from a red cell concentrate |
| US4596657A (en) * | 1982-06-04 | 1986-06-24 | Miles Laboratories, Inc. | Blood bag system with integral filtering means |
| US4680025A (en) * | 1982-08-24 | 1987-07-14 | Baxter Travenol Laboratories, Inc. | Blood component collection systems and methods |
| DE3410286C2 (de) * | 1984-03-21 | 1986-01-23 | Fresenius AG, 6380 Bad Homburg | Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens |
| US4753739A (en) * | 1986-01-27 | 1988-06-28 | Engineering & Research Associates | Blood bag support system |
| US4936998A (en) * | 1986-03-28 | 1990-06-26 | Asahi Medical Co., Ltd. | Filter medium for selectively removing leucocytes |
| US4915848A (en) * | 1986-04-21 | 1990-04-10 | Miles Laboratories, Inc. | Red blood cell filtering system |
| US4810378A (en) * | 1986-04-21 | 1989-03-07 | Miles Laboratories, Inc. | Red blood cell filtering system |
| US4855063A (en) * | 1986-04-21 | 1989-08-08 | Miles Laboratories, Inc. | Red blood cell filtering system |
| US4714457A (en) * | 1986-09-15 | 1987-12-22 | Robert Alterbaum | Method and apparatus for use in preparation of fibrinogen from a patient's blood |
| US4898573A (en) * | 1986-10-29 | 1990-02-06 | Asahi Medical Co., Ltd. | Blood components collector unit |
| US4923620A (en) * | 1987-10-20 | 1990-05-08 | Pall Corporation | Device for depletion of the leukocyte content of blood and blood components |
| US4925572A (en) * | 1987-10-20 | 1990-05-15 | Pall Corporation | Device and method for depletion of the leukocyte content of blood and blood components |
| US4909949A (en) * | 1987-10-26 | 1990-03-20 | Engineering & Research Associates | Bridge for suspending a blood collection bag |
| US4880548A (en) * | 1988-02-17 | 1989-11-14 | Pall Corporation | Device and method for separating leucocytes from platelet concentrate |
| EP0349188B1 (en) * | 1988-06-23 | 1992-09-02 | ASAHI MEDICAL Co., Ltd. | Method for separating blood into blood components, and blood components separator unit |
| US4892668A (en) * | 1988-10-05 | 1990-01-09 | Engineering & Research Associates, Inc. | Blood collection bag support |
| NL8802888A (nl) * | 1988-11-23 | 1990-06-18 | Akzo Nv | Filter en werkwijze voor het vervaardigen van een leucocytenarme trombocytensuspensie. |
| US4943287A (en) * | 1989-07-17 | 1990-07-24 | Miles Inc. | Red blood cell storage system |
| ATE193454T1 (de) * | 1989-09-12 | 2000-06-15 | Pall Corp | Verfahren und vorrichtung zur behandlung von menschlichem blut für die transfusion |
| US4997577A (en) * | 1989-12-20 | 1991-03-05 | Baxter International Inc. | Systems and methods for removing undesired matter from blood cells |
| US5089146A (en) * | 1990-02-12 | 1992-02-18 | Miles Inc. | Pre-storage filtration of platelets |
| US5092996A (en) * | 1991-02-19 | 1992-03-03 | Miles Inc. | Blood filtering system |
-
1990
- 1990-11-06 US US07/609,654 patent/US5100564A/en not_active Expired - Lifetime
-
1991
- 1991-11-05 ZA ZA918788A patent/ZA918788B/xx unknown
- 1991-11-06 MX MX9101962A patent/MX9101962A/es not_active IP Right Cessation
- 1991-11-06 GB GB9411033A patent/GB2277464B/en not_active Expired - Lifetime
- 1991-11-06 EP EP00202302A patent/EP1038541A3/en not_active Withdrawn
- 1991-11-06 JP JP4501061A patent/JP2570906B2/ja not_active Expired - Lifetime
- 1991-11-06 CA CA002095623A patent/CA2095623C/en not_active Expired - Lifetime
- 1991-11-06 EP EP92900488A patent/EP0556303B1/en not_active Expired - Lifetime
- 1991-11-06 DE DE4192629T patent/DE4192629T1/de active Pending
- 1991-11-06 AU AU90861/91A patent/AU651646B2/en not_active Expired
- 1991-11-06 CN CN91111546A patent/CN1028964C/zh not_active Expired - Fee Related
- 1991-11-06 EP EP03015217A patent/EP1348455A1/en not_active Withdrawn
- 1991-11-06 NL NL9120023A patent/NL194639C/nl not_active IP Right Cessation
- 1991-11-06 GB GB9308933A patent/GB2264884B/en not_active Expired - Lifetime
- 1991-11-06 ES ES92900488T patent/ES2153827T3/es not_active Expired - Lifetime
- 1991-11-06 AT AT0902991A patent/AT404674B/de not_active IP Right Cessation
- 1991-11-06 NZ NZ240489A patent/NZ240489A/xx not_active IP Right Cessation
- 1991-11-06 DE DE4143690A patent/DE4143690B4/de not_active Expired - Lifetime
- 1991-11-06 WO PCT/US1991/008316 patent/WO1992007656A2/en active IP Right Grant
-
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- 1993-04-27 SE SE9301418A patent/SE514255C2/sv not_active IP Right Cessation
- 1993-05-04 DK DK199300505A patent/DK175916B1/da not_active IP Right Cessation
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- 1993-05-06 KR KR1019930701356A patent/KR100193172B1/ko not_active IP Right Cessation
-
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- 1994-05-12 GB GB9409533A patent/GB9409533D0/en active Pending
- 1994-08-25 CN CN94109364A patent/CN1103317A/zh active Pending
- 1994-10-19 AU AU75934/94A patent/AU667282B2/en not_active Expired
-
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- 1999-12-16 SE SE9904615A patent/SE514256C2/sv not_active IP Right Cessation
-
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- 2002-02-20 FI FI20020342A patent/FI116366B/fi not_active IP Right Cessation
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