FI109336B - System och förfarande för behandling av biologiska vätskor - Google Patents

System och förfarande för behandling av biologiska vätskor Download PDF

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Publication number
FI109336B
FI109336B FI932031A FI932031A FI109336B FI 109336 B FI109336 B FI 109336B FI 932031 A FI932031 A FI 932031A FI 932031 A FI932031 A FI 932031A FI 109336 B FI109336 B FI 109336B
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porous
biological fluid
blood
medium
porous medium
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FI932031A
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Finnish (fi)
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FI932031A0 (fi
FI932031A (fi
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David B Pall
Vlado I Matkovich
Thomas Bormann
Thomas C Gsell
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Pall Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A61M1/0227—Multiple bag systems for separating or storing blood components with filters and means for securing the filter against damage, e.g. during centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0231—Multiple bag systems for separating or storing blood components with gas separating means, e.g. air outlet through microporous membrane or gas bag
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/029—Separating blood components present in distinct layers in a container, not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633—Blood component filters, e.g. leukocyte filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3643—Priming, rinsing before or after use
    • A61M1/3644—Mode of operation
    • A61M1/3646—Expelling the residual body fluid after use, e.g. back to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3643—Priming, rinsing before or after use
    • A61M1/3644—Mode of operation
    • A61M1/3652—Mode of operation using gas, e.g. air
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/147—Microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/16—Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/087—Single membrane modules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0415—Plasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0427—Platelets; Thrombocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0429—Red blood cells; Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0439—White blood cells; Leucocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/12—Flow characteristics the flow being spirally in a plane, e.g. against a plane side of a membrane filter element
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/04—Specific process operations in the feed stream; Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B2005/0435—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with adapters for centrifuge tubes or bags

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Claims (30)

1. Behandlingssystem (10) för ett biologiskt flui-5 dum, kännetecknat av, att systemet omfattar: en första behällare (11) ; en andra behällare (41) som star i strömnings-förbindelse med den första behällaren, en tredje behällare (18) som stär i strömnings-10 förbindelse med den första behällaren, ett första poröst medium som anordnats mellan den första behällaren (11) och den andra behällaren (41) , varvid det första porösa mediet omfattar ätminstone ett av följande: ett leukocytutarmande medium (13), ett 15 spärrmedium (12) mot röda blodkroppar, och ett kombinerat leukocytutarmande och röda blodkroppar utestängande medium (12); och ett andra poröst medium (17) som anordnats mellan den första behällaren (11) och den tredje behällaren 20 (18), varvid det andra porösa mediet (17) omfattar ett lukocytutarmande medium.
2. System enligt patentkrav 1, känneteck-n a t av, att det första porösa mediet (12, 13) och det ’ : andra porösa mediet (17) omfattar syntetiska polymer- i , **: 25 fibrer. 1 · ·_;
3. System enligt patentkrav 1 eller 2, känne tecknat av, att det första porösa mediet (12, 13) och det andra porösa mediet (17) omfattar polybutylen-tereftaiatfibrer. . , 30
4. System enligt patentkrav 1 eller 2, kanne- * » » t e c k n a t av, att det första porösa mediet (12, 13) och det andra porösa mediet (17) omfattar fibrer, vilka modifierats genom att de utsatts för en monomer som omfattar en polymeriserbar grupp och en hydroxylhaltig 35 grupp. i i i 109336 74
5. System enligt patentkrav 4, känneteck-n a t av, att fibrerna i det första porösa mediet (12, 13. modifierats med en blandning av monomerer, vilken om-fattar hydroxietylmetakrylat och metakrylsyra.
6. System enligt patentkrav 5, känneteck- n a t av, att viktförhällandet metakrylsyra till hyd- roxietylmetakrylatmonomer ligger mellan 0,01:1 och 0,5:1.
7. System enligt patentkrav 1, känneteck- n a t av, att det första porösa mediet (12) tilläter 10 blodplattor att passera genom sig men blockerar röda blodkroppar.
8. System enligt patentkrav 1, känneteck- n a t av, att det första porösa mediet (12, 13) omfattar ett fibermedium och att fiberytarean hos det första 15 porösa mediet är 0,3 - 2,0 m2.
9. System enligt patentkrav 8, känneteck-n a t av, att fiberytarean hos det första porösa mediet (12, 13) är 0,35 - 0,6 m2.
10. System enligt patentkrav 1, kanne- 20 tecknat av, att strömningsarean hos det första porösa mediet (12, 13) är 2,5 - 10 cm2.
11. System enligt patentkrav 1, k ä n n e - tecknat av, att det första porösa mediet (12, 13) '·'· omfattar ett fibermedium och att fiberytarean hos det 25 första porösa mediet är 0,04 - 0,3 m2.
,·, ; 12. System enligt patentkrav 1, k ä n n e - « · tecknat av, att det första porösa mediet (12, 13) ,omfattar ett fibermedium och att fiberytarean hos det I * · *’ ' första porösa mediet är 0,08 - 1,0 m2.
13. System enligt patentkrav 1, k ä n n e - » · tecknat av, att det första porösa mediet (12, 13) » : * har en hälrumsvolym av 71 - 83 %.
14. System enligt patentkrav 1, k ä n n e - * · tecknat av, att det första porösa mediet (12, 13) » · 35 har en hälrumsvolym av 50 - 89 %. * i > t 75 109336
15. System enligt patentkrav 1, känne- t e c k n a t av, att det första porösa mediet (12, 13) har en zeta-potential frän -3 tili -30 millivolt vid ett pH av 7,3.
16. System enligt patentkrav 1, känne- t e c k n a t av, att det första porösa mediet (12, 13) har ett CWST som överstiger 70 dyn/cm.
17. System enligt patentkrav 1, känne- t e c k n a t av, att det andra porösa mediet (17) har 10 en hälrumsvolym av 60 - 90 %.
18. System enligt patentkrav 1, känne- t e c k n a t av, att strömningsarean hos det andra porösa mediet (17) är 30 - 60 cm2.
19. System enligt patentkrav 1, känne- 15 tecknat av, att det andra porösa mediet (17) har ett CWST som överstiger 53 dyn/cm.
20. System enligt patentkrav 1, som ytterligare omfattar ätminstone ett gasinlopp (51, 53) anordnat uppströms i förhällande tili det första och/eller andra 20 porösa mediet och/eller ätminstone ett gasutlopp (52, 54) :·*: anordnat nedströms i förhällande tili det första och/eller andra mediet.
“·. 21. System enligt nägot av patentkraven 1 - 20, kännetecknat av, att det biologiska fluidumet / 25 omf attar en blodprodukt.
*./ 22. System enligt nägot av patent kraven 1 - 21, ‘ ’ kännetecknat av, att det systemet är ett ste- rilt, slutet system (10). • ♦
23. System enligt nägot av patentkraven 1 - 22, 30 kännetecknat av, att systemet (10) är lämp- ligt för behandling inom ca. 8 timmar efter mottagandet • I .···’, av det biologiska fluidumet.
24. Förfarande för behandling av ett biologiskt fluidum, kännetecknat av, att det omfattar: 35 separering av det biologiska fluidumet i ett supernatantskikt (31) och ett sedimentskikt (32); j ledande av supernatantskiktet (31) av det biolo- 76 109336 giska fluidumet genom ett första poröst medium, varvid det första porösa mediet omfattar ätminstone av följande: ett leukocytutarmande medium (13), ett spärrmedium (12) mot röda blodkroppar, och ett kombinerat leukocytutarman-5 de och röda blodkroppar utestängande medium (12); och ledande av sedimentskiktet (32) frän det biologis-ka fluidumet genom ett andra poröst medium (17), varvid det andra porösa mediet omfattar ett leukocytutarmande medium. 10
25. Förfarande enligt patentkrav 24, kanne- t e c k n a t av, att det ytterligare omfattar pressande av supernatantskiktet (31) tili det första porösa mediet och pressande av sedimentskiktet (32) tili ett andra poröst medium i sekvens. 15
26. Förfarande enligt patentkrav 24, kanne- t e c k n a t av, att ledandet av supernatantskiktet (31) av det biologiska fluidumet genom ett första poröst medium omfattar ledande av supernatantskiktet genom ett spärrmedium (12) mot röda blodkroppar eller genom ett 20 kombinerat leukocytutarmande och röda blodkroppar hejdan-:·; de medium (12) tills mediet blockerats. V.
27. Förfarande enligt patentkrav 24, k ä n n e - '*·. t e c k n a t av, att det ytterligare omfattar införande . : av gas genom ett gasinlopp (51, 53) och/eller utdrivande ' 25 av gas genom ett gasutlopp (52, 54).
28. Förfarande enlig nägot av patentkraven 24 - 27, kännetecknat av, att det biologiska fluidumet omfattar en blodprodukt. , i
29. Förfarande enligt nägot av patentkraven 24 - 30 28, kännetecknat av, att det ytterligare om- fattar behandling av ett biologiskt fluidum i ett ste- 1 » ,···_ rilt, slutet system (10) .
30. Förfarande enligt nägot av patentkraven 24 -29, kännetecknat av, att det omfattar behand-:ti>: 35 ling av det biologiska fluidumet inom ca. 8 timmar.
FI932031A 1990-11-06 1993-05-05 System och förfarande för behandling av biologiska vätskor FI109336B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60965490 1990-11-06
US07/609,654 US5100564A (en) 1990-11-06 1990-11-06 Blood collection and processing system
US9108316 1991-11-06
PCT/US1991/008316 WO1992007656A2 (en) 1990-11-06 1991-11-06 System and method for processing biological fluids

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FI932031A0 FI932031A0 (fi) 1993-05-05
FI932031A FI932031A (fi) 1993-05-05
FI109336B true FI109336B (sv) 2002-07-15

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FI932031A FI109336B (sv) 1990-11-06 1993-05-05 System och förfarande för behandling av biologiska vätskor
FI20020342A FI116366B (sv) 1990-11-06 2002-02-20 Förfarande för att hantera en biologisk fluid

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US (1) US5100564A (sv)
EP (3) EP1038541A3 (sv)
JP (1) JP2570906B2 (sv)
KR (1) KR100193172B1 (sv)
CN (2) CN1028964C (sv)
AT (1) AT404674B (sv)
AU (2) AU651646B2 (sv)
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Families Citing this family (175)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344561A (en) * 1989-05-09 1994-09-06 Pall Corporation Device for depletion of the leucocyte content of blood and blood components
US5360545A (en) * 1989-09-12 1994-11-01 Pall Corporation Filter for obtaining platelets
US5316674A (en) * 1989-09-12 1994-05-31 Pall Corporation Device for processing blood for human transfusion
US5152905A (en) * 1989-09-12 1992-10-06 Pall Corporation Method for processing blood for human transfusion
US5258126A (en) * 1989-09-12 1993-11-02 Pall Corporation Method for obtaining platelets
US5266219A (en) * 1989-12-28 1993-11-30 Pall Corporation Device and method for separating plasma from blood
US5126054A (en) * 1990-05-24 1992-06-30 Pall Corporation Venting means
US5302299A (en) * 1990-05-24 1994-04-12 Pall Corporation Biological semi-fluid processing assembly
US5863436A (en) * 1990-05-24 1999-01-26 Pall Corporation Venting system
US5362406A (en) * 1990-07-27 1994-11-08 Pall Corporation Leucocyte depleting filter device and method of use
US5217627A (en) * 1990-11-06 1993-06-08 Pall Corporation System and method for processing biological fluid
US5935092A (en) * 1990-12-20 1999-08-10 Baxter International Inc. Systems and methods for removing free and entrained contaminants in plasma
US5498336A (en) * 1991-02-22 1996-03-12 Terumo Kabushiki Kaisha Leukocyte-removing filter and leukocyte-removing apparatus furnished therewith
US5672481A (en) * 1991-10-23 1997-09-30 Cellpro, Incorporated Apparatus and method for particle separation in a closed field
CA2074671A1 (en) * 1991-11-04 1993-05-05 Thomas Bormann Device and method for separating plasma from a biological fluid
CA2072378C (en) * 1991-11-21 2000-12-26 Vlado Ivan Matkovich System for processing separate containers of biological fluid
US5690835A (en) 1991-12-23 1997-11-25 Baxter International Inc. Systems and methods for on line collection of cellular blood components that assure donor comfort
US5549834A (en) 1991-12-23 1996-08-27 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
AU4107396A (en) * 1992-03-02 1996-06-06 Cerus Corporation Synthetic media for blood components
CA2137797C (en) * 1992-06-10 2003-01-07 Vlado I. Matkovich System for treating transition zone material
CA2083075A1 (en) * 1992-06-10 1993-12-11 Vlado I. Matkovich System for treating transition zone material
PL307164A1 (en) * 1992-07-13 1995-05-02 Pall Corp Automatic system for and method of processing biological fluids
WO1994001193A1 (en) * 1992-07-13 1994-01-20 Pall Corporation Automated system and method for processing biological fluid
GB9218581D0 (en) * 1992-09-02 1992-10-14 Pall Corp Removal of unwanted fluids from processed blood products
DE69324754T2 (de) * 1992-10-07 2000-01-13 Asahi Medical Co Filter und System zur Trennung der Leukozyten
EP0668786A1 (en) * 1992-11-03 1995-08-30 Chronomed, Inc. Methods and procedures for preparing red blood fractions
US5316681A (en) * 1992-11-06 1994-05-31 Baxter International Inc. Method of filtering body fluid using a rinse chamber bag
JP3246620B2 (ja) * 1993-02-22 2002-01-15 旭メディカル株式会社 白血球除去フィルター支持体
US5547591A (en) * 1993-06-01 1996-08-20 Asahi Medical Co., Ltd. Method for separating a blood material into blood components by centrifugation, and centrifugal apparatus
GB9311988D0 (en) * 1993-06-10 1993-07-28 Pall Corp Device and method for separating plasma from a blood product
CA2143830C (en) * 1993-07-26 2003-11-25 Richard I. Brown Systems and methods for reducing leukocytes in cellular products
FR2712825B1 (fr) * 1993-11-23 1996-02-23 Jouan Procédé de traitement par centrifugation d'un liquide conditionné dans des poches à parois souples, reliées à au moins un filtre.
US5545339A (en) * 1994-02-25 1996-08-13 Pall Corporation Method for processing biological fluid and treating separated component
US5591350A (en) * 1994-04-15 1997-01-07 Pall Corporation Iodine disinfection method using a gaseous iodine treated porous medium
US5547108A (en) * 1994-08-02 1996-08-20 Pall Corporation Expressor
US6045701A (en) * 1994-10-17 2000-04-04 Baxter International Inc. Method of filtering a fluid suspension with a membrane having a particular coating
US5972217A (en) * 1994-10-17 1999-10-26 Baxter International Inc. Blood cell separation devices having a membrane with particular coating
US5647985A (en) * 1994-10-17 1997-07-15 Baxter International Inc. Whole blood leukodepletion and platelet filter
US6746482B2 (en) 1994-10-17 2004-06-08 Baxter International Inc. Method for producing medical devices and devices so produced
US6306454B1 (en) * 1994-10-17 2001-10-23 Baxter International Inc. Method for producing improved medical devices and devices so produced
US5660731A (en) * 1994-11-08 1997-08-26 Pall Corporation Filter for separating photoactive agent
US7169547B2 (en) 1994-12-05 2007-01-30 New York Blood Center, Inc. High concentration white blood cells as a therapeutic product
US5585007A (en) * 1994-12-07 1996-12-17 Plasmaseal Corporation Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant
US5728306A (en) * 1994-12-23 1998-03-17 Baxter International Inc. Leukodepletion filter and method for filtering leukocytes from freshly drawn blood
US5630946A (en) * 1995-02-15 1997-05-20 Pall Corporation Method for processing a biological fluid including leukocyte removal in an extracorporeal circuit
US5939319A (en) * 1995-04-18 1999-08-17 Cobe Laboratories, Inc. Particle separation method and apparatus
US5913768A (en) * 1995-04-18 1999-06-22 Cobe Laboratories, Inc. Particle filter apparatus
US6053856A (en) * 1995-04-18 2000-04-25 Cobe Laboratories Tubing set apparatus and method for separation of fluid components
US5721024A (en) * 1995-06-07 1998-02-24 Pall Corporation Material for flexible medical products
US6544727B1 (en) 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
US5759413A (en) * 1995-06-07 1998-06-02 Baxter International Inc. Systems and method for estimating platelet counts using a spleen mobilization function
US6140040A (en) * 1995-10-06 2000-10-31 Advanced Minerals Corporation Method of mechanically separating microparticles suspended in fluids using particulate media
US5865785A (en) * 1996-02-23 1999-02-02 Baxter International Inc. Systems and methods for on line finishing of cellular blood products like platelets harvested for therapeutic purposes
US20020115585A1 (en) * 1996-06-07 2002-08-22 Hei Derek J. Method and devices for the removal of psoralens from blood products
US6190855B1 (en) * 1996-10-28 2001-02-20 Baxter International Inc. Systems and methods for removing viral agents from blood
US6168718B1 (en) 1996-11-08 2001-01-02 Pall Corporation Method for purifying blood plasma and apparatus suitable therefor
AU736156B2 (en) * 1996-12-24 2001-07-26 Pall Corporation Biological fluid processing
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US5954971A (en) * 1997-01-07 1999-09-21 Haemonetics Corporation Pumped-filter blood-processing apparatus and methods
DE19712298C2 (de) * 1997-03-24 1999-05-20 Fresenius Ag Vorrichtung und Verfahren zum Trennen von Blut in Blutkomponenten
US7611831B2 (en) * 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US6051146A (en) * 1998-01-20 2000-04-18 Cobe Laboratories, Inc. Methods for separation of particles
US6497823B1 (en) * 1998-01-23 2002-12-24 Pall Corporation Method for processing a biological fluid
US6669905B1 (en) * 1998-05-21 2003-12-30 Baxter International Inc. Systems and methods for collecting plasma that is free or virtually free of cellular blood species
FR2781681B1 (fr) * 1998-07-31 2000-11-24 Maco Pharma Sa Ensemble de poches en circuit clos, destine a recueillir, separer et purifier differents constituants du sang a partir d'un prelevement de sang total
US6153113A (en) * 1999-02-22 2000-11-28 Cobe Laboratories, Inc. Method for using ligands in particle separation
US6334842B1 (en) 1999-03-16 2002-01-01 Gambro, Inc. Centrifugal separation apparatus and method for separating fluid components
US6945411B1 (en) * 1999-03-16 2005-09-20 Pall Corporation Biological fluid filter and system
GB9909630D0 (en) 1999-04-28 1999-06-23 Zeneca Ltd Reactor
US6629919B2 (en) 1999-06-03 2003-10-07 Haemonetics Corporation Core for blood processing apparatus
EP1057534A1 (en) 1999-06-03 2000-12-06 Haemonetics Corporation Centrifugation bowl with filter core
AU6498600A (en) * 1999-07-29 2001-02-19 Baxter International Inc. Sampling tube holder for blood sampling system
US6524231B1 (en) * 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
US6875191B2 (en) * 1999-09-03 2005-04-05 Baxter International Inc. Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter
JP2001071353A (ja) * 1999-09-06 2001-03-21 Tokuyama Sekisui Ind Corp 血液回路用フィルタハウジングの射出成形方法
US7651474B2 (en) 1999-10-01 2010-01-26 Caridianbct, Inc. Method and apparatus for leukoreduction of red blood cells
US7686779B1 (en) 1999-10-01 2010-03-30 Caridian BCT, Inc Extracorporeal blood processing methods and apparatus
US6354986B1 (en) 2000-02-16 2002-03-12 Gambro, Inc. Reverse-flow chamber purging during centrifugal separation
EP1331977B1 (en) * 2000-09-20 2009-07-01 Thermo Fisher Scientific (Asheville) LLC Blood centrifuge cup having a replaceable compartment for filter support
ATE530212T1 (de) * 2001-04-26 2011-11-15 Asahi Kasei Medical Co Ltd Blutfiltrationsmethode
FR2827176B1 (fr) * 2001-07-12 2003-12-19 Biolog Procede de fiabilisation de la tracabilite des prelevements sanguins lors des operations d'extraction notamment du plasma et des globules rouges
US7264608B2 (en) * 2001-12-05 2007-09-04 Fenwal, Inc. Manual processing systems and methods for providing blood components conditioned for pathogen inactivation
EP1455860B1 (en) * 2001-12-10 2011-08-31 CaridianBCT, Inc. Method for the leukoreduction of red blood cells
US20030173274A1 (en) * 2002-02-01 2003-09-18 Frank Corbin Blood component separation device, system, and method including filtration
CA2642653A1 (en) * 2002-04-16 2003-10-30 Gambro Bct, Inc. Blood component processing system, apparatus and method
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US7374678B2 (en) * 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20060278588A1 (en) 2002-05-24 2006-12-14 Woodell-May Jennifer E Apparatus and method for separating and concentrating fluids containing multiple components
AU2003249642A1 (en) * 2002-05-24 2003-12-12 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
ITTO20020736A1 (it) * 2002-08-21 2004-02-22 Fresenius Hemocare Italia Srl Filtro per leucociti e suo impiego per l'impoverimento di prodotti del sangue da leucociti.
ITTO20020820A1 (it) * 2002-09-20 2004-03-21 Fresenius Hemocare Italia S R L Dispositivo e procedimento per separare il sangue in componenti del sangue impoveriti di leucociti.
US7297272B2 (en) * 2002-10-24 2007-11-20 Fenwal, Inc. Separation apparatus and method
WO2004052270A1 (ja) * 2002-12-12 2004-06-24 Asahi Kasei Kabushiki Kaisha ウイルス除去バッグ及びそれを用いたウイルス除去方法
US20070031812A1 (en) 2003-06-20 2007-02-08 Pall Corporation Processing of platelet-containing biological fluids
US20050124073A1 (en) 2003-12-09 2005-06-09 Entire Interest Fat collection and preparation system and method
US20050137517A1 (en) * 2003-12-19 2005-06-23 Baxter International Inc. Processing systems and methods for providing leukocyte-reduced blood components conditioned for pathogen inactivation
US20050208501A1 (en) 2004-03-16 2005-09-22 Ambion, Inc. Process and reagents for extraction of RNA from fractionated blood leukocytes
US20070209708A1 (en) * 2004-06-22 2007-09-13 Gambro, Inc. Bag Assembly for the Separation of a Composite Liquid and Method for Manufacturing it
WO2006086201A2 (en) 2005-02-07 2006-08-17 Hanuman Llc Platelet rich plasma concentrate apparatus and method
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
ES2426941T3 (es) * 2005-02-07 2013-10-25 Hanuman Llc Aparato y procedimiento de concentrados de plasma rico en plaquetas
WO2007041716A1 (en) * 2005-10-05 2007-04-12 Gambro Bct, Inc. Method and apparatus for leukoreduction of red blood cells
DE202005015644U1 (de) * 2005-10-06 2007-02-15 Andreas Hettich Gmbh & Co. Kg Zentrifugenbecher mit Halterung für Blutbeutel
WO2007100986A2 (en) * 2006-02-24 2007-09-07 Rosetta Inpharmatics Llc Extraction and diagnostic fluid devices, systems and methods of use
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8430813B2 (en) * 2006-05-26 2013-04-30 Depuy Spine, Inc. Illuminated surgical access system including a surgical access device and integrated light emitter
US20080147240A1 (en) * 2006-12-19 2008-06-19 Gambro Bct Inc. Apparatus for separating a composite liquid with process control on a centrifuge rotor
US20080156728A1 (en) * 2006-12-29 2008-07-03 Bryan Blickhan Biological fluid filtration systems and methods
US8603821B2 (en) * 2007-03-07 2013-12-10 Jms Co., Ltd. Method for preparing serum and serum preparation apparatus
EP2134386B1 (en) * 2007-04-06 2018-12-26 Fenwal, Inc. Biological fluid filtration systems and methods
EP2146794B1 (en) 2007-04-12 2016-10-19 Biomet Biologics, LLC Buoy suspension fractionation system
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
CN101842111A (zh) 2007-08-31 2010-09-22 密执安州立大学董事会 选择性细胞隔离装置及其相关方法
CA2749771C (en) * 2008-01-28 2018-05-01 Milux Holding S.A. A drainage device comprising an active filter
EP2567692B1 (en) 2008-02-27 2016-04-06 Biomet Biologics, LLC Use of a device for obtaining interleukin-1 receptor antagonist rich solutions
US8075468B2 (en) * 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
US8685258B2 (en) * 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
EP2254991B1 (en) * 2008-02-29 2018-08-22 Biomet Manufacturing, LLC A system and process for separating a material
US8702637B2 (en) 2008-04-14 2014-04-22 Haemonetics Corporation System and method for optimized apheresis draw and return
US8454548B2 (en) 2008-04-14 2013-06-04 Haemonetics Corporation System and method for plasma reduced platelet collection
US8628489B2 (en) * 2008-04-14 2014-01-14 Haemonetics Corporation Three-line apheresis system and method
JP5229665B2 (ja) * 2008-05-13 2013-07-03 学校法人立命館 血漿又は血清分離方法、及び血漿又は血清分離装置
US8012077B2 (en) * 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
FR2934489B1 (fr) * 2008-07-31 2011-11-11 Imv Technologies Sachet de conditionnement d'une substance biologique comportant des ouvertures de suspension a un dispositif de support, et bande formee de tels sachets.
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8834402B2 (en) 2009-03-12 2014-09-16 Haemonetics Corporation System and method for the re-anticoagulation of platelet rich plasma
US8313954B2 (en) * 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US9011800B2 (en) * 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US8875893B2 (en) * 2010-02-05 2014-11-04 Fenwal, Inc. Medical containers for use in blood collection and processing and medical systems, methods and apparatus for use in blood collection and processing
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
WO2012051595A1 (en) 2010-10-15 2012-04-19 Cytopherx, Inc. Cytopheresic cartridge and use thereof
US8808978B2 (en) 2010-11-05 2014-08-19 Haemonetics Corporation System and method for automated platelet wash
JP5785713B2 (ja) * 2010-12-28 2015-09-30 ファミリーセルバンク株式会社 白血球分画回収装置
US9302042B2 (en) 2010-12-30 2016-04-05 Haemonetics Corporation System and method for collecting platelets and anticipating plasma return
US11386993B2 (en) 2011-05-18 2022-07-12 Fenwal, Inc. Plasma collection with remote programming
CA2860831A1 (en) 2012-01-09 2013-07-18 H. David Humes Cartridge and method for increasing myocardial function
US9421317B2 (en) * 2012-06-08 2016-08-23 Pall Corporation Cell harvesting device and system
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
CN112076628A (zh) 2012-12-03 2020-12-15 Emd密理博公司 用于冗余无菌过滤的方法和装置
WO2014127122A1 (en) 2013-02-18 2014-08-21 Terumo Bct, Inc. System for blood separation with a separation chamber having an internal gravity valve
US10143725B2 (en) 2013-03-15 2018-12-04 Biomet Biologics, Llc Treatment of pain using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US20140271589A1 (en) 2013-03-15 2014-09-18 Biomet Biologics, Llc Treatment of collagen defects using protein solutions
US10208095B2 (en) 2013-03-15 2019-02-19 Biomet Manufacturing, Llc Methods for making cytokine compositions from tissues using non-centrifugal methods
US9943639B2 (en) * 2013-10-28 2018-04-17 Boston Scientific Scimed, Inc. Fluid management system and methods
US11213776B2 (en) * 2013-12-13 2022-01-04 Asahi Kasei Medical Co., Ltd. Leukocyte removal filter material and leukocyte removal method
US9968738B2 (en) 2014-03-24 2018-05-15 Fenwal, Inc. Biological fluid filters with molded frame and methods for making such filters
US10159778B2 (en) 2014-03-24 2018-12-25 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
US9782707B2 (en) 2014-03-24 2017-10-10 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
US10376627B2 (en) 2014-03-24 2019-08-13 Fenwal, Inc. Flexible biological fluid filters
US9796166B2 (en) 2014-03-24 2017-10-24 Fenwal, Inc. Flexible biological fluid filters
CA2951398C (en) * 2014-06-24 2021-06-08 Parker-Hannifin Corporation Multiple identification point automated parameter assurance method
US10512888B2 (en) 2014-06-24 2019-12-24 Parker-Hannifin Corporation Multiple identification point automated parameter assurance method
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
CN107708761B (zh) * 2015-05-07 2022-04-29 艾尼蒂斯科技公司 使用相应方法分离血液的封闭式一次性无菌多血袋系统
US10675394B2 (en) * 2015-05-07 2020-06-09 Aenitis Technologies Multiple fluid bag system
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
CN105641988B (zh) * 2015-12-02 2018-01-30 重庆浪尖渝力科技有限公司 生物样品混悬液自动分离设备的挂板组件
FR3055557B1 (fr) 2016-09-08 2018-10-12 Maco Pharma Sa Unite de filtration comprenant un bord peripherique courbe
FR3055556B1 (fr) 2016-09-08 2018-10-12 Maco Pharma Unite de filtration comprenant des portions en dome
FR3047184A1 (fr) 2016-10-03 2017-08-04 Biolog Dispositif de stockage d'elements
US10758652B2 (en) 2017-05-30 2020-09-01 Haemonetics Corporation System and method for collecting plasma
US10792416B2 (en) 2017-05-30 2020-10-06 Haemonetics Corporation System and method for collecting plasma
US11065376B2 (en) 2018-03-26 2021-07-20 Haemonetics Corporation Plasmapheresis centrifuge bowl
KR102345761B1 (ko) 2018-05-21 2022-01-03 펜월, 인크. 혈장 수집 체적의 최적화를 위한 시스템
US11412967B2 (en) 2018-05-21 2022-08-16 Fenwal, Inc. Systems and methods for plasma collection
US11148083B2 (en) * 2019-12-27 2021-10-19 Pall Corporation Method and system for recovering fluid
US11498023B2 (en) 2019-12-27 2022-11-15 Pall Corporation Method and system for recovering fluid
FR3132209A1 (fr) 2022-02-03 2023-08-04 Cellquest Bioréacteur pour la production d’un médicament biologique et support pour un tel bioréacteur
CN114504012B (zh) * 2022-02-23 2023-06-27 李�真 一种畜禽屠宰的机体主动脉放血集血方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US492362A (en) 1893-02-21 Alois opiioven
US3800947A (en) * 1971-07-16 1974-04-02 P Smith Reagent tube and centrifugally operated solid-liquid separating device
US4111199A (en) * 1977-03-31 1978-09-05 Isaac Djerassi Method of collecting transfusable granulocytes by gravity leukopheresis
GB2018151B (en) * 1978-03-06 1982-12-08 Asahi Chemical Ind Seperation of leukocytes from leukocyte-containing suspension by filtration
DE3065899D1 (en) * 1979-09-22 1984-01-19 Hettich Andreas Fa Centrifuge with system of bloodbag for the separation of blood components
JPS603367B2 (ja) * 1979-10-09 1985-01-28 旭化成株式会社 白血球分離法および白血球分離材
US4322298A (en) * 1981-06-01 1982-03-30 Advanced Blood Component Technology, Inc. Centrifugal cell separator, and method of use thereof
US4416778A (en) * 1981-10-20 1983-11-22 Neocyte, Inc. Means for preparing neocyte enriched blood
US4543084A (en) * 1982-02-09 1985-09-24 Bailey Mary L Blood bag support for centrifugation
US4596657A (en) * 1982-06-04 1986-06-24 Miles Laboratories, Inc. Blood bag system with integral filtering means
US4767541A (en) * 1982-06-04 1988-08-30 Miles Laboratories, Inc. Method of removing platelets and white cells from a red cell concentrate
US4919823A (en) * 1982-06-04 1990-04-24 Miles Inc. Blood bag system with integral filtering means
US4680025A (en) * 1982-08-24 1987-07-14 Baxter Travenol Laboratories, Inc. Blood component collection systems and methods
DE3410286C2 (de) * 1984-03-21 1986-01-23 Fresenius AG, 6380 Bad Homburg Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens
US4753739A (en) * 1986-01-27 1988-06-28 Engineering & Research Associates Blood bag support system
JPH0651060B1 (sv) * 1986-03-28 1994-07-06 Asahi Medical Co
US4855063A (en) * 1986-04-21 1989-08-08 Miles Laboratories, Inc. Red blood cell filtering system
US4915848A (en) * 1986-04-21 1990-04-10 Miles Laboratories, Inc. Red blood cell filtering system
US4810378A (en) * 1986-04-21 1989-03-07 Miles Laboratories, Inc. Red blood cell filtering system
US4714457A (en) * 1986-09-15 1987-12-22 Robert Alterbaum Method and apparatus for use in preparation of fibrinogen from a patient's blood
US4898573A (en) * 1986-10-29 1990-02-06 Asahi Medical Co., Ltd. Blood components collector unit
US4925572A (en) * 1987-10-20 1990-05-15 Pall Corporation Device and method for depletion of the leukocyte content of blood and blood components
US4923620A (en) * 1987-10-20 1990-05-08 Pall Corporation Device for depletion of the leukocyte content of blood and blood components
US4909949A (en) * 1987-10-26 1990-03-20 Engineering & Research Associates Bridge for suspending a blood collection bag
US4880548A (en) * 1988-02-17 1989-11-14 Pall Corporation Device and method for separating leucocytes from platelet concentrate
DE68902698C5 (de) * 1988-06-23 2005-07-14 Asahi Medical Co. Ltd. Verfahren zur Trennung von Blut in Blutkomponenten und Einheit zur Trennung von Blutkomponenten.
US4892668A (en) * 1988-10-05 1990-01-09 Engineering & Research Associates, Inc. Blood collection bag support
NL8802888A (nl) * 1988-11-23 1990-06-18 Akzo Nv Filter en werkwijze voor het vervaardigen van een leucocytenarme trombocytensuspensie.
US4943287A (en) * 1989-07-17 1990-07-24 Miles Inc. Red blood cell storage system
DE69032500T2 (de) * 1989-09-12 1998-11-26 Pall Corp Verfahren und vorrichtung zur behandlung von blut für die menschliche transfusion
US4997577A (en) * 1989-12-20 1991-03-05 Baxter International Inc. Systems and methods for removing undesired matter from blood cells
US5089146A (en) * 1990-02-12 1992-02-18 Miles Inc. Pre-storage filtration of platelets
US5092996A (en) * 1991-02-19 1992-03-03 Miles Inc. Blood filtering system

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GB9308933D0 (en) 1993-07-14
NL194639C (nl) 2002-10-04
NL194639B (nl) 2002-06-03
AU7593494A (en) 1995-04-06
NZ240489A (en) 1993-05-26
SE514255C2 (sv) 2001-01-29
AU667282B2 (en) 1996-03-14
EP1348455A1 (en) 2003-10-01
ZA918788B (en) 1992-08-26
SE9301418D0 (sv) 1993-04-27
DK50593D0 (da) 1993-05-04
JP2570906B2 (ja) 1997-01-16
AU651646B2 (en) 1994-07-28
GB2277464B (en) 1995-02-15
SE9904615D0 (sv) 1999-12-16
KR100193172B1 (ko) 1999-06-15
ES2153827T3 (es) 2001-03-16
GB9409533D0 (en) 1994-06-29
AT404674B (de) 1999-01-25
CA2095623A1 (en) 1992-05-07
GB2264884B (en) 1995-02-15
DE4143690B4 (de) 2008-01-10
DE4192629T1 (de) 1993-11-18
JPH06500942A (ja) 1994-01-27
EP1038541A2 (en) 2000-09-27
CA2095623C (en) 1998-09-15
FI932031A0 (fi) 1993-05-05
FI116366B (sv) 2005-11-15
DK50593A (da) 1993-05-04
WO1992007656A3 (en) 1993-01-21
CN1103317A (zh) 1995-06-07
GB2264884A (en) 1993-09-15
SE9301418L (sv) 1993-04-27
FI932031A (fi) 1993-05-05
EP0556303B1 (en) 2001-02-07
FI20020342A (sv) 2002-02-20
CN1028964C (zh) 1995-06-21
EP1038541A3 (en) 2000-11-15
MX9101962A (es) 1993-08-01
GB2277464A (en) 1994-11-02
EP0556303A1 (en) 1993-08-25
WO1992007656A2 (en) 1992-05-14
ATA902991A (de) 1998-06-15
SE9904615L (sv) 1999-12-16
SE514256C2 (sv) 2001-01-29
US5100564A (en) 1992-03-31
CN1062299A (zh) 1992-07-01
AU9086191A (en) 1992-05-26
DK175916B1 (da) 2005-06-27
NL9120023A (nl) 1993-09-01
GB9411033D0 (en) 1994-07-27

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