FI107339B - Lääkeaineiden läpäisynopeutta säätävä kalvo tai matriisi - Google Patents

Lääkeaineiden läpäisynopeutta säätävä kalvo tai matriisi Download PDF

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Publication number
FI107339B
FI107339B FI981506A FI981506A FI107339B FI 107339 B FI107339 B FI 107339B FI 981506 A FI981506 A FI 981506A FI 981506 A FI981506 A FI 981506A FI 107339 B FI107339 B FI 107339B
Authority
FI
Finland
Prior art keywords
groups
elastomer
lower alkyl
film
polyalkylene oxide
Prior art date
Application number
FI981506A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI981506A0 (fi
FI981506A (fi
Inventor
Jarkko Ruohonen
Matti Lehtinen
Harri Jukarainen
Tommi Markkula
Juha Ala-Sorvari
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of FI981506A0 publication Critical patent/FI981506A0/fi
Priority to FI981506A priority Critical patent/FI107339B/fi
Priority to TW088109291A priority patent/TWI237571B/zh
Priority to CO99035747A priority patent/CO5060523A1/es
Priority to DK99931285T priority patent/DK1124902T3/da
Priority to AU47839/99A priority patent/AU752895B2/en
Priority to PL99345103A priority patent/PL193485B1/pl
Priority to EP99931285A priority patent/EP1124902B1/fr
Priority to NZ508275A priority patent/NZ508275A/xx
Priority to SK1894-2000A priority patent/SK285325B6/sk
Priority to CA002336149A priority patent/CA2336149C/fr
Priority to BRPI9911140-3A priority patent/BR9911140B1/pt
Priority to ES99931285T priority patent/ES2237120T3/es
Priority to DE69923992T priority patent/DE69923992T2/de
Priority to PCT/FI1999/000511 priority patent/WO2000000550A1/fr
Priority to CNB998081388A priority patent/CN1176999C/zh
Priority to CZ20004749A priority patent/CZ299613B6/cs
Priority to JP2000557307A priority patent/JP2002519467A/ja
Priority to HU0102600A priority patent/HU229159B1/hu
Priority to EEP200000788A priority patent/EE04685B1/xx
Priority to RU2001102606/04A priority patent/RU2201794C2/ru
Priority to PT99931285T priority patent/PT1124902E/pt
Priority to AT99931285T priority patent/ATE290049T1/de
Priority to CNB031429661A priority patent/CN1269909C/zh
Priority to KR1020007015121A priority patent/KR100599868B1/ko
Priority to PE1999000584A priority patent/PE20000935A1/es
Priority to ARP990103082A priority patent/AR018952A1/es
Priority to UA2001010652A priority patent/UA71566C2/uk
Publication of FI981506A publication Critical patent/FI981506A/fi
Priority to ZA200006986A priority patent/ZA200006986B/en
Priority to NO20006581A priority patent/NO327955B1/no
Priority to BG105081A priority patent/BG65148B1/bg
Application granted granted Critical
Publication of FI107339B publication Critical patent/FI107339B/fi
Priority to HK02100469A priority patent/HK1038939A1/xx
Priority to US10/298,197 priority patent/US6887948B2/en
Priority to US10/298,195 priority patent/US6794464B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/10—Block- or graft-copolymers containing polysiloxane sequences
    • C08L83/12—Block- or graft-copolymers containing polysiloxane sequences containing polyether sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Polymers & Plastics (AREA)
  • Silicon Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Wrappers (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Materials For Medical Uses (AREA)
FI981506A 1998-06-30 1998-06-30 Lääkeaineiden läpäisynopeutta säätävä kalvo tai matriisi FI107339B (fi)

Priority Applications (33)

Application Number Priority Date Filing Date Title
FI981506A FI107339B (fi) 1998-06-30 1998-06-30 Lääkeaineiden läpäisynopeutta säätävä kalvo tai matriisi
TW088109291A TWI237571B (en) 1998-06-30 1999-06-04 A membrane or matrix for controlling the permeation rate of drugs
CO99035747A CO5060523A1 (es) 1998-06-30 1999-06-08 Una membrana o matriz para controlar la velocidad de penetracion de farmacos
JP2000557307A JP2002519467A (ja) 1998-06-30 1999-06-11 薬物の透過速度を調節する膜又はマトリックス
PT99931285T PT1124902E (pt) 1998-06-30 1999-06-11 Membrana ou matriz para controlo da velocidade de permeacao de farmacos
PL99345103A PL193485B1 (pl) 1998-06-30 1999-06-11 Błona lub matryca do kontrolowania prędkości przenikania leku
EP99931285A EP1124902B1 (fr) 1998-06-30 1999-06-11 Membrane ou matrice permettant de reguler la vitesse de permeation des medicaments
NZ508275A NZ508275A (en) 1998-06-30 1999-06-11 A membrane or matrix containing siloxane based elastomer for controlling the permeation rate of drugs
SK1894-2000A SK285325B6 (sk) 1998-06-30 1999-06-11 Membrána alebo matrica na riadenie rýchlosti permeácie liekov, ktorá obsahuje elastomérnu kompozíciu na báze siloxánu, obsahujúca aspoň jeden elastomér a prípadne nezosieťovaný polymér a spôsob prípravy elastoméru
CA002336149A CA2336149C (fr) 1998-06-30 1999-06-11 Membrane ou matrice permettant de reguler la vitesse de permeation des medicaments
BRPI9911140-3A BR9911140B1 (pt) 1998-06-30 1999-06-11 membrana ou matriz para controlar a velocidade de permeação de fármacos e método para preparação de um elastÈmero.
ES99931285T ES2237120T3 (es) 1998-06-30 1999-06-11 Membrana o matriz para el control de la velocidad de permeacion de farmacos.
DE69923992T DE69923992T2 (de) 1998-06-30 1999-06-11 Membran oder Matrix zur Steuerung der Permeationsrate eines Wirkstoffs
PCT/FI1999/000511 WO2000000550A1 (fr) 1998-06-30 1999-06-11 Membrane ou matrice permettant de reguler la vitesse de permeation des medicaments
CNB998081388A CN1176999C (zh) 1998-06-30 1999-06-11 一种控制药物渗透速率的膜或基体
CZ20004749A CZ299613B6 (cs) 1998-06-30 1999-06-11 Membrána nebo matrice pro rízení rychlosti permeace léku obsahující kompozici na bázi elastomeru siloxanu a zpusob prípravy elastomeru
DK99931285T DK1124902T3 (da) 1998-06-30 1999-06-11 Membran eller matrix til kontrol af permeationsgraden for medikamenter
HU0102600A HU229159B1 (hu) 1998-06-30 1999-06-11 Gyógyszerek permeációs sebességét szabályozó membrán vagy mátrix
EEP200000788A EE04685B1 (et) 1998-06-30 1999-06-11 Ravimi l„bimiskiirust kontrolliv membraan v?i maatriks
RU2001102606/04A RU2201794C2 (ru) 1998-06-30 1999-06-11 Мембрана или матрица для регулирования скорости проникновения лекарственных средств
AU47839/99A AU752895B2 (en) 1998-06-30 1999-06-11 A membrane or matrix for controlling the permeation rate of drugs
AT99931285T ATE290049T1 (de) 1998-06-30 1999-06-11 Membran oder matrix zur steuerung der freisetzungsgeschwindigkeit von arzneistoffen
CNB031429661A CN1269909C (zh) 1998-06-30 1999-06-11 制备基于硅氧烷的弹性体的方法
KR1020007015121A KR100599868B1 (ko) 1998-06-30 1999-06-11 약물의 투과속도 조절을 위한 막 또는 매트릭스
PE1999000584A PE20000935A1 (es) 1998-06-30 1999-06-25 Una membrana o matriz para controlar la velocidad de penetracion de farmacos
ARP990103082A AR018952A1 (es) 1998-06-30 1999-06-25 Una membrana o matriz para controlar la velocidad de penetracion de farmacos
UA2001010652A UA71566C2 (uk) 1998-06-30 1999-11-06 Мембрана для регулювання швидкості проникнення лікарських засобів
ZA200006986A ZA200006986B (en) 1998-06-30 2000-11-28 A membrane or matrix for controlling the permeation rate of drugs.
NO20006581A NO327955B1 (no) 1998-06-30 2000-12-21 Membran eller matriks for a regulere permeeringshastigheten for medikamenter
BG105081A BG65148B1 (bg) 1998-06-30 2000-12-21 Мембрана или матрица за контрол на степента на проникване на лекарствени средства
HK02100469A HK1038939A1 (en) 1998-06-30 2002-01-21 A membrane or matrix for controlling the permeation rate of drugs.
US10/298,197 US6887948B2 (en) 1998-06-30 2002-11-18 Method for preparing a siloxane-based elastomer composition
US10/298,195 US6794464B2 (en) 1998-06-30 2002-11-18 Membrane or matrix for controlling the permeation rate of drugs

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI981506 1998-06-30
FI981506A FI107339B (fi) 1998-06-30 1998-06-30 Lääkeaineiden läpäisynopeutta säätävä kalvo tai matriisi

Publications (3)

Publication Number Publication Date
FI981506A0 FI981506A0 (fi) 1998-06-30
FI981506A FI981506A (fi) 1999-12-31
FI107339B true FI107339B (fi) 2001-07-13

Family

ID=8552104

Family Applications (1)

Application Number Title Priority Date Filing Date
FI981506A FI107339B (fi) 1998-06-30 1998-06-30 Lääkeaineiden läpäisynopeutta säätävä kalvo tai matriisi

Country Status (29)

Country Link
EP (1) EP1124902B1 (fr)
JP (1) JP2002519467A (fr)
KR (1) KR100599868B1 (fr)
CN (2) CN1176999C (fr)
AR (1) AR018952A1 (fr)
AT (1) ATE290049T1 (fr)
AU (1) AU752895B2 (fr)
BG (1) BG65148B1 (fr)
BR (1) BR9911140B1 (fr)
CA (1) CA2336149C (fr)
CO (1) CO5060523A1 (fr)
CZ (1) CZ299613B6 (fr)
DE (1) DE69923992T2 (fr)
EE (1) EE04685B1 (fr)
ES (1) ES2237120T3 (fr)
FI (1) FI107339B (fr)
HK (1) HK1038939A1 (fr)
HU (1) HU229159B1 (fr)
NO (1) NO327955B1 (fr)
NZ (1) NZ508275A (fr)
PE (1) PE20000935A1 (fr)
PL (1) PL193485B1 (fr)
PT (1) PT1124902E (fr)
RU (1) RU2201794C2 (fr)
SK (1) SK285325B6 (fr)
TW (1) TWI237571B (fr)
UA (1) UA71566C2 (fr)
WO (1) WO2000000550A1 (fr)
ZA (1) ZA200006986B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008110666A1 (fr) 2007-03-12 2008-09-18 Bayer Schering Pharma Oy Utilisation du tocophérol

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
AU2002210580A1 (en) * 2000-10-20 2002-04-29 Leiras Oy Drug delivery system
EP1438942A1 (fr) 2003-01-17 2004-07-21 Schering Oy Dispositif d'administration de médicament otologique et rhinologique
CN101006124B (zh) * 2004-08-25 2010-11-24 联合碳化化学及塑料技术有限责任公司 聚合薄膜
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
EP2140860A1 (fr) 2008-07-03 2010-01-06 Bayer Schering Pharma Oy Procédé de contraception amélioré
FI20080523A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
FI20080524A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
US11992431B2 (en) 2008-09-17 2024-05-28 Bayer Oy Inserter
CA2736020C (fr) 2008-09-17 2016-12-06 Bayer Oy Dispositif d'introduction
FI122579B (fi) 2010-10-29 2012-03-30 Bayer Oy Insertteri
CN102008909B (zh) * 2010-12-13 2012-10-10 大连欧科膜技术工程有限公司 一种气体分离复合膜的制备方法
CN102068914B (zh) * 2010-12-13 2012-10-10 大连欧科膜技术工程有限公司 一种气体分离复合膜的制备方法
KR20150005548A (ko) 2012-04-23 2015-01-14 바이엘 파마 악티엔게젤샤프트 월경과다증의 치료에서의 18-메틸-15β,16β-메틸렌-19-노르-20-스피록스-4-엔-3-온 시스템의 용도, 및 자궁 출혈 장애의 치료를 위한 18-메틸-15β,16β-메틸렌-19-노르-20-스피록스-4-엔-3-온을 함유하는 자궁내 시스템
TW201350122A (zh) 2012-04-23 2013-12-16 Bayer Pharma AG １８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內用途，包含１８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內系統，及其於避孕及婦科治療之用途
PE20160534A1 (es) * 2013-10-18 2016-06-15 Bayer Oy Sistema de administracion intrauterina
WO2016180764A1 (fr) 2015-05-13 2016-11-17 Bayer Oy Dispositif d'administration de médicament à action prolongée et son utilisation dans la contraception
WO2018202574A1 (fr) 2017-05-04 2018-11-08 Bayer Oy Système d'administration de médicament intravaginal, procédé de fabrication d'un tel système et son utilisation dans des thérapies gynécologiques et en contraception
EP3536735B1 (fr) * 2018-03-05 2020-10-14 Evonik Operations GmbH Copolymères bloc de polyéther-siloxane réticulés ainsi que leur utilisation pour la fabrication de mousses en polyuréthane

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889108A (en) * 1997-06-02 1999-03-30 Dow Corning Corporation Thickening solvents with elastomeric silicone polyethers

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008110666A1 (fr) 2007-03-12 2008-09-18 Bayer Schering Pharma Oy Utilisation du tocophérol

Also Published As

Publication number Publication date
NO327955B1 (no) 2009-10-26
TWI237571B (en) 2005-08-11
BG105081A (en) 2001-09-28
CN1308653A (zh) 2001-08-15
ES2237120T3 (es) 2005-07-16
PT1124902E (pt) 2005-07-29
KR20010053346A (ko) 2001-06-25
ZA200006986B (en) 2001-05-23
NO20006581L (no) 2000-12-29
CA2336149C (fr) 2007-01-02
AU752895B2 (en) 2002-10-03
CA2336149A1 (fr) 2000-01-06
CZ299613B6 (cs) 2008-09-17
UA71566C2 (uk) 2004-12-15
NO20006581D0 (no) 2000-12-21
NZ508275A (en) 2002-09-27
HU229159B1 (hu) 2013-09-30
PL345103A1 (en) 2001-12-03
CO5060523A1 (es) 2001-07-30
ATE290049T1 (de) 2005-03-15
HUP0102600A3 (en) 2004-04-28
DE69923992T2 (de) 2006-04-13
CN1176999C (zh) 2004-11-24
EP1124902A1 (fr) 2001-08-22
CZ20004749A3 (cs) 2001-10-17
WO2000000550A1 (fr) 2000-01-06
RU2201794C2 (ru) 2003-04-10
AU4783999A (en) 2000-01-17
EP1124902B1 (fr) 2005-03-02
HUP0102600A2 (hu) 2001-11-28
BG65148B1 (bg) 2007-04-30
CN1488678A (zh) 2004-04-14
CN1269909C (zh) 2006-08-16
JP2002519467A (ja) 2002-07-02
AR018952A1 (es) 2001-12-12
EE200000788A (et) 2002-04-15
BR9911140B1 (pt) 2009-08-11
DE69923992D1 (de) 2005-04-07
FI981506A0 (fi) 1998-06-30
BR9911140A (pt) 2001-03-06
HK1038939A1 (en) 2002-04-04
PE20000935A1 (es) 2000-09-18
PL193485B1 (pl) 2007-02-28
KR100599868B1 (ko) 2006-07-12
SK18942000A3 (sk) 2001-07-10
EE04685B1 (et) 2006-08-15
FI981506A (fi) 1999-12-31
SK285325B6 (sk) 2006-11-03

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Owner name: BAYER SCHERING PHARMA OY

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