CO5060523A1 - Una membrana o matriz para controlar la velocidad de penetracion de farmacos - Google Patents

Una membrana o matriz para controlar la velocidad de penetracion de farmacos

Info

Publication number
CO5060523A1
CO5060523A1 CO99035747A CO99035747A CO5060523A1 CO 5060523 A1 CO5060523 A1 CO 5060523A1 CO 99035747 A CO99035747 A CO 99035747A CO 99035747 A CO99035747 A CO 99035747A CO 5060523 A1 CO5060523 A1 CO 5060523A1
Authority
CO
Colombia
Prior art keywords
membrane
matrix
control
pharmacos
penetration speed
Prior art date
Application number
CO99035747A
Other languages
English (en)
Inventor
Harri Jukarainen
Tommi Markkula
Aka-Sorvari Juha
Matti Lehtinen
Ruohonen Jarkko
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of CO5060523A1 publication Critical patent/CO5060523A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/10—Block- or graft-copolymers containing polysiloxane sequences
    • C08L83/12—Block- or graft-copolymers containing polysiloxane sequences containing polyether sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Silicon Polymers (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Wrappers (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La presente invención se relaciona con una membrana o matrizpara controlar la velocidad de penetración opermeación de un fármaco, comprendiendo dicha membrana o matriz una composición elastomérica basada en siloxanos, que comprende por lo menos un elastómero caracterizada por que la composición elastomérica comprende grupos de poli (óxido de alquileno), y porque los grupos de poli (óxido de alquileno), están presentes en el elastómero o polímero como injertos rematados por alcoxi de unidades de polisiloxanos, o como bloques, estando dichos injertos o bloques enlazados a las unidades de polisiloxanos por enlaces de silicio con carbono, o como una mezcla de estas formas.
CO99035747A 1998-06-30 1999-06-08 Una membrana o matriz para controlar la velocidad de penetracion de farmacos CO5060523A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI981506A FI107339B (fi) 1998-06-30 1998-06-30 Lääkeaineiden läpäisynopeutta säätävä kalvo tai matriisi

Publications (1)

Publication Number Publication Date
CO5060523A1 true CO5060523A1 (es) 2001-07-30

Family

ID=8552104

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99035747A CO5060523A1 (es) 1998-06-30 1999-06-08 Una membrana o matriz para controlar la velocidad de penetracion de farmacos

Country Status (29)

Country Link
EP (1) EP1124902B1 (es)
JP (1) JP2002519467A (es)
KR (1) KR100599868B1 (es)
CN (2) CN1176999C (es)
AR (1) AR018952A1 (es)
AT (1) ATE290049T1 (es)
AU (1) AU752895B2 (es)
BG (1) BG65148B1 (es)
BR (1) BR9911140B1 (es)
CA (1) CA2336149C (es)
CO (1) CO5060523A1 (es)
CZ (1) CZ299613B6 (es)
DE (1) DE69923992T2 (es)
EE (1) EE04685B1 (es)
ES (1) ES2237120T3 (es)
FI (1) FI107339B (es)
HK (1) HK1038939A1 (es)
HU (1) HU229159B1 (es)
NO (1) NO327955B1 (es)
NZ (1) NZ508275A (es)
PE (1) PE20000935A1 (es)
PL (1) PL193485B1 (es)
PT (1) PT1124902E (es)
RU (1) RU2201794C2 (es)
SK (1) SK285325B6 (es)
TW (1) TWI237571B (es)
UA (1) UA71566C2 (es)
WO (1) WO2000000550A1 (es)
ZA (1) ZA200006986B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
WO2002032433A1 (en) * 2000-10-20 2002-04-25 Leiras Oy Drug delivery system
EP1438942A1 (en) 2003-01-17 2004-07-21 Schering Oy An otorhinological drug delivery device
ES2300048T3 (es) * 2004-08-25 2008-06-01 UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION Pelicula polimerica.
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
KR101484509B1 (ko) 2007-03-12 2015-01-21 베이어 오와이 토코페롤을 사용하는 방법
EP2140860A1 (en) 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
FI20080524A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
US11992431B2 (en) 2008-09-17 2024-05-28 Bayer Oy Inserter
FI20080523A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
CN102159162B (zh) 2008-09-17 2013-04-24 拜耳公司 插入器
FI122579B (fi) 2010-10-29 2012-03-30 Bayer Oy Insertteri
CN102068914B (zh) * 2010-12-13 2012-10-10 大连欧科膜技术工程有限公司 一种气体分离复合膜的制备方法
CN102008909B (zh) * 2010-12-13 2012-10-10 大连欧科膜技术工程有限公司 一种气体分离复合膜的制备方法
CA2871001A1 (en) 2012-04-23 2013-10-31 Bayer Pharma Aktiengesellschaft Application of 18-methyl-15ss,16ss-methylene-19-nor-20-spirox-4-en-3-one systems in the treatment of menorrhagia, as well as intrauterine systems containing 18-methyl-15ss,16ss-methylene-19-nor-20-spirox-4-en-3-one for treating uterine bleeding disorders
TW201350122A (zh) 2012-04-23 2013-12-16 Bayer Pharma AG １８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內用途，包含１８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內系統，及其於避孕及婦科治療之用途
TN2016000134A1 (en) * 2013-10-18 2017-10-06 Bayer Oy Intrauterine delivery system.
EP3294300A1 (en) 2015-05-13 2018-03-21 Bayer Oy A long acting drug delivery device and its use in contraception
WO2018202574A1 (en) 2017-05-04 2018-11-08 Bayer Oy Intravaginal drug delivery system, method for manufacturing such system and its use in gynecological therapies and contraception
ES2834450T3 (es) 2018-03-05 2021-06-17 Evonik Operations Gmbh Copolímeros en bloques de poliéter-siloxano reticulados, así como su empleo para la producción de espumas de poliuretano

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5889108A (en) * 1997-06-02 1999-03-30 Dow Corning Corporation Thickening solvents with elastomeric silicone polyethers

Also Published As

Publication number Publication date
HU229159B1 (hu) 2013-09-30
EP1124902A1 (en) 2001-08-22
DE69923992D1 (de) 2005-04-07
CN1308653A (zh) 2001-08-15
BR9911140A (pt) 2001-03-06
CN1488678A (zh) 2004-04-14
PE20000935A1 (es) 2000-09-18
DE69923992T2 (de) 2006-04-13
CA2336149A1 (en) 2000-01-06
AU4783999A (en) 2000-01-17
HUP0102600A2 (hu) 2001-11-28
TWI237571B (en) 2005-08-11
NO20006581L (no) 2000-12-29
WO2000000550A1 (en) 2000-01-06
JP2002519467A (ja) 2002-07-02
UA71566C2 (uk) 2004-12-15
KR20010053346A (ko) 2001-06-25
ES2237120T3 (es) 2005-07-16
CN1269909C (zh) 2006-08-16
KR100599868B1 (ko) 2006-07-12
FI981506A (fi) 1999-12-31
BR9911140B1 (pt) 2009-08-11
HUP0102600A3 (en) 2004-04-28
CZ299613B6 (cs) 2008-09-17
NO327955B1 (no) 2009-10-26
FI107339B (fi) 2001-07-13
AR018952A1 (es) 2001-12-12
AU752895B2 (en) 2002-10-03
ZA200006986B (en) 2001-05-23
SK285325B6 (sk) 2006-11-03
PL193485B1 (pl) 2007-02-28
NO20006581D0 (no) 2000-12-21
EE04685B1 (et) 2006-08-15
CA2336149C (en) 2007-01-02
BG65148B1 (bg) 2007-04-30
RU2201794C2 (ru) 2003-04-10
CN1176999C (zh) 2004-11-24
HK1038939A1 (en) 2002-04-04
ATE290049T1 (de) 2005-03-15
SK18942000A3 (sk) 2001-07-10
PL345103A1 (en) 2001-12-03
FI981506A0 (fi) 1998-06-30
NZ508275A (en) 2002-09-27
CZ20004749A3 (cs) 2001-10-17
BG105081A (en) 2001-09-28
EP1124902B1 (en) 2005-03-02
PT1124902E (pt) 2005-07-29
EE200000788A (et) 2002-04-15

Similar Documents

Publication Publication Date Title
CO5060523A1 (es) Una membrana o matriz para controlar la velocidad de penetracion de farmacos
AR026647A1 (es) Dispositivo para el suministro de farmacos que tienen propiedades antiprogestinicas
PE20030316A1 (es) Sistema de suministro de dos o mas agentes terapeuticamente activos
BRPI0411071A (pt) sistemas de reticulação para polìmeros de hidroxila
AR025815A1 (es) MÉTODO PARA CONTROLAR LA PERMEACIoN DE UN FÁRMACO DURANTE UN PERíODO PROLONGADO MEDIANTE EL USO DE UN ELASToMERO BASADO EN SILOXANO.
ES2577431T3 (es) Composición de caucho de silicona termo-endurecible para laminados de caucho
AR037196A1 (es) Telas compuestas que tienen regiones polimericas elasticas discretas
BRPI0516698A (pt) composição de resina epóxi curável, processo para preparar uma resina epóxi curável, compósito e laminado
ATE452939T1 (de) Elastomerblend
BR0114416A (pt) Composições elastoméricas halogenadas que apresentam viscosidade acentuada
BRPI0516702A (pt) composição de verniz de resina epóxi para laminados curável, processo para preparar uma composição de verniz para laminados de resina epóxi curável, processo para preparar um laminado, laminado e pré-impregnado
ATE554141T1 (de) Herstellung von silikon-kautschuk-elastomeren
DE602004005266D1 (de) Topische Zusammensetzung enthaltend ein Organopolysiloxan-Elastomer, sowie eine wässrige Dispersion eines Silikon-Block-Copolymers
ES2170831T3 (es) Sistema polimero multicapa que comprende al menos una capa de termoplastico ingenieril y al menos una capa de composicion suave al tecto, y composiciones correspondientes.
ATE456393T1 (de) Haarfärbemittel enthaltend organosilikon- copolymere mit aminogruppen und polyoxyalkylengruppen sowie deren verwendung
ES2096988T3 (es) Organopolisiloxanos que contienen grupos hidrofilos.
DE50008862D1 (de) Verwendung von Polyorganosiloxan zur Verminderung des Cold Stress Whitenings
BR0003891A (pt) Composição de borracha contendo polìmero de polialquileno terminado em hidroxila e pneu com banda de rodagem da mesma
DE602004016776D1 (de) Härtbare silikonzusammensetzung und ihre verwendung als klebstoff
IT1251150B (it) Composizione termoplastica tenacizzata a base di polifenilenetere e poliammide
ES2186255T3 (es) Metodo de modeado de un reten de anillo torico en componentes usando moldes de enclavamiento y aparato para ello.
FI952776A (fi) Verkkoutuva tai verkkoutunut, tarttumaton ja painokelvoton silikonikoostumus
ES2094786T3 (es) Procedimiento para la separacion de componentes en un liquido organico y membrana semipermeable compuesta para el mismo.
ATE165381T1 (de) Kondensations- und additionspolymere mit n,n'- verbrückten bis-tetramethylpiperidinyloxy- gruppierungen
KR970021207A (ko) 수팽윤성 폴리머 및 수팽윤성 조성물