PE20030316A1 - Sistema de suministro de dos o mas agentes terapeuticamente activos - Google Patents

Sistema de suministro de dos o mas agentes terapeuticamente activos

Info

Publication number
PE20030316A1
PE20030316A1 PE2002000827A PE2002000827A PE20030316A1 PE 20030316 A1 PE20030316 A1 PE 20030316A1 PE 2002000827 A PE2002000827 A PE 2002000827A PE 2002000827 A PE2002000827 A PE 2002000827A PE 20030316 A1 PE20030316 A1 PE 20030316A1
Authority
PE
Peru
Prior art keywords
active agents
therapeutically active
delivery system
poly
same
Prior art date
Application number
PE2002000827A
Other languages
English (en)
Inventor
Juha Ala-Sorvari
Timo Haapakumpu
Antti Keinanen
Manja Ahola
Marko Aaltonen
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of PE20030316A1 publication Critical patent/PE20030316A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

QUE COMPRENDE: 1)UN NUCLEO QUE COMPRENDE AL MENOS DOS AGENTES TERAPEUTICAMENTE ACTIVOS, CADA UNO DE LOS CUALES TIENE UNA VELOCIDAD DE LIBERACION; 2)UNA MEMBRANA QUE ENCAPSULA A (1) QUE TIENE AL MENOS DOS CAPAS DE GROSOR DIFERENTE. CONSISTIENDO AMB0S (1) Y (2) DE UNA COMPOSICION DE ELASTOMERO IGUAL O DIFERENTE, SELECCIONADA DE: a)POLI(DIMETILSILOXANO); b)UN ELASTOMERO CON BASE DE SILOXANO QUE COMPRENDE GRUPOS 3,3,3-TRIFLUOROPROPILO UNIDOS A LOS ATOMOS DE Si DE LAS UNIDADES DE SILOXANO; c)GRUPOS POLI(OXIDO DE ALQUILENO) PRESENTES COMO INJERTOS TERMINADOS CON ALCOXI O BLOQUES UNIDOS A LAS UNIDADES DE POLISILOXANO MEDIANTE ENLACES DE SILICIO-CARBONO, O COMO UNA MEZCLA DE ESTAS FORMAS; Y d)UNA COMBINACION DE AL MENOS DOS DE LOS MISMOS. TIENE APLICACION COMO IMPLANTE, SISTEMA INTRAUTERINO, SISTEMA INTRACERVICAL, ENTRE OTROS
PE2002000827A 2001-08-31 2002-08-28 Sistema de suministro de dos o mas agentes terapeuticamente activos PE20030316A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31597201P 2001-08-31 2001-08-31

Publications (1)

Publication Number Publication Date
PE20030316A1 true PE20030316A1 (es) 2003-04-03

Family

ID=23226904

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002000827A PE20030316A1 (es) 2001-08-31 2002-08-28 Sistema de suministro de dos o mas agentes terapeuticamente activos

Country Status (14)

Country Link
US (1) US20040247674A1 (es)
EP (1) EP1427390A1 (es)
JP (1) JP2005503389A (es)
KR (1) KR20040036928A (es)
CN (1) CN1289064C (es)
AR (1) AR036310A1 (es)
AU (1) AU2002313517B2 (es)
CA (1) CA2457979A1 (es)
HU (1) HUP0401438A3 (es)
NO (1) NO20041315L (es)
PE (1) PE20030316A1 (es)
PL (1) PL367961A1 (es)
RU (1) RU2302883C2 (es)
WO (1) WO2003017971A1 (es)

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PL2279729T3 (pl) * 2003-07-17 2017-02-28 Banner Life Sciences Llc Preparaty o kontrolowanym uwalnianiu
ES2561463T3 (es) * 2003-08-21 2016-02-26 Addbio Ab Dispositivo de implante recubierto con bisfosfonato y método para el mismo
CA2571314A1 (en) * 2004-06-22 2006-01-05 Greystone Medical Group, Inc. Methods for treatment of wounds using time release compositions
ES2293193T5 (es) 2004-07-13 2012-06-13 Bayer Schering Pharma Oy Sistema de suministro retardado con descarga inicial controlada
US7494665B1 (en) 2004-07-30 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymers containing siloxane monomers
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
EP2001350A4 (en) * 2006-03-20 2013-04-17 Teva Womens Health Inc FLEXIBLE COMPRESSED INTRAVAGINAL RINGS, METHOD FOR THEIR PRODUCTION AND USE AND DEVICE FOR THEIR PRODUCTION
US8828981B2 (en) 2007-02-06 2014-09-09 George Creasy Progesterone for the treatment or prevention of spontaneous preterm birth
US8741329B2 (en) 2007-09-21 2014-06-03 Merck Sharp & Dohme B.V. Drug delivery system
EP2057972A1 (en) * 2007-11-07 2009-05-13 N.V. Organon Intrauterine deposit
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
DK2062569T3 (da) * 2007-11-22 2011-08-29 Bayer Oy Vaginalt afgivelsessystem
EP2062568A1 (en) * 2007-11-22 2009-05-27 Bayer Schering Pharma Oy Vaginal delivery system
US9314524B2 (en) * 2007-12-31 2016-04-19 Calla Therapeutics Llc Topical formulations of Flucytosine
DE102008006416A1 (de) * 2008-01-28 2009-07-30 Mayer, Thomas, Dr. med. Clindamycin zur Verwendung bei der Behandlung oder Vorbeugung der bakteriellen Vaginosis
SI2359807T1 (sl) * 2008-02-04 2017-10-30 Ferring B.V. Monolitni intravaginalni obroč, ki vsebuje progesteron ter postopki za njegovo izdelavo in uporabo
EP2140860A1 (en) * 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
FI20080524A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
CA2736020C (en) 2008-09-17 2016-12-06 Bayer Oy An inserter
FI20080523A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
US11992431B2 (en) 2008-09-17 2024-05-28 Bayer Oy Inserter
LT2381932T (lt) * 2009-01-29 2018-11-12 Fondazione Irccs Istituto Nazionale Dei Tumori Intracervikalinė priemonė vaistams leisti vietiniu bei zoniniu mastu, gydant gimdos kaklelio piktybinį naviką
FI20095550A0 (fi) * 2009-05-19 2009-05-19 Bayer Schering Pharma Oy Vaginaalinen antojärjestelmä
FI122579B (fi) 2010-10-29 2012-03-30 Bayer Oy Insertteri
CN102525722A (zh) * 2010-12-30 2012-07-04 辽宁爱母医疗科技有限公司 具有记忆效应的智能型复方孕二烯酮阴道环制剂及其应用
EP2476409A1 (en) * 2011-01-14 2012-07-18 Université Catholique De Louvain Implant comprising a core and a tube encasing the core
DE202012012761U1 (de) * 2011-04-07 2013-10-29 Arstat, Inc. Mit Arzneimittel versehene intravaginale Vorrichtung und pharmazeutische Zusammensetzung zur Behandlung von Menstruationsschmerzen und übermäßigem Menstruationsblutverlust
US10028858B2 (en) 2011-07-11 2018-07-24 Medicines360 Intrauterine systems, IUD insertion devices, and related methods and kits therefor
EP2607451B8 (de) 2011-12-20 2019-03-27 Merck Patent GmbH Flüssigkristallines Medium
AR089765A1 (es) 2012-01-23 2014-09-17 Bayer Oy Un sistema para el suministro de un farmaco
EP2953558B1 (en) 2013-02-06 2019-08-28 Sillender, Mark Embryo transfer catheter
EP2953678B1 (en) * 2013-02-06 2020-03-25 Sillender, Mark Therapeutic substance transfer catheter
SE539540C2 (sv) * 2013-09-12 2017-10-10 Qpharma Ab Ett läkemedelsavgivningssystem för en eller flera aktiva beståndsdelar
US9963556B2 (en) * 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
PE20160534A1 (es) * 2013-10-18 2016-06-15 Bayer Oy Sistema de administracion intrauterina
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
EP3079659B1 (en) 2013-12-11 2020-10-28 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10772842B2 (en) * 2015-01-09 2020-09-15 Patheon Softgels Inc. Abuse-deterrent opioids
WO2015184407A1 (en) * 2014-05-30 2015-12-03 Textile-Based Delivery, Inc. Drug delivery systems and related methods of use
RS59148B1 (sr) 2015-01-21 2019-09-30 Bayer Oy Sistem za isporuku leka koji sadrži nesteroidno antiinflamatorno (nsail) i progestogeno jedinjenje i metode za njegovu proizvodnju
WO2016180764A1 (en) 2015-05-13 2016-11-17 Bayer Oy A long acting drug delivery device and its use in contraception
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US11173291B2 (en) * 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11344526B2 (en) * 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11338119B2 (en) * 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
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Also Published As

Publication number Publication date
CN1549703A (zh) 2004-11-24
NO20041315L (no) 2004-03-30
KR20040036928A (ko) 2004-05-03
PL367961A1 (en) 2005-03-07
AR036310A1 (es) 2004-08-25
RU2302883C2 (ru) 2007-07-20
US20040247674A1 (en) 2004-12-09
AU2002313517B2 (en) 2007-09-06
JP2005503389A (ja) 2005-02-03
EP1427390A1 (en) 2004-06-16
RU2004109575A (ru) 2005-08-20
HUP0401438A2 (hu) 2004-11-29
CN1289064C (zh) 2006-12-13
WO2003017971A1 (en) 2003-03-06
HUP0401438A3 (en) 2008-04-28
CA2457979A1 (en) 2003-03-06

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