AR036310A1 - Un sistema de suministro - Google Patents

Un sistema de suministro

Info

Publication number
AR036310A1
AR036310A1 ARP020103244A ARP020103244A AR036310A1 AR 036310 A1 AR036310 A1 AR 036310A1 AR P020103244 A ARP020103244 A AR P020103244A AR P020103244 A ARP020103244 A AR P020103244A AR 036310 A1 AR036310 A1 AR 036310A1
Authority
AR
Argentina
Prior art keywords
elastomer composition
core
membrane
poly
different
Prior art date
Application number
ARP020103244A
Other languages
English (en)
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of AR036310A1 publication Critical patent/AR036310A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Un sistema de suministro que comprende un núcleo y una membrana que encapsula dicho núcleo, en donde dicho núcleo y dicha membrana consisten esencialmente de una composición de elastómero igual o diferente, en donde dicho núcleo comprende al menos dos agentes terapéuticamente activos, cada uno de los cuales tiene una velocidad de liberación. La membrana puede consistir en al menos dos capas, cuyo grosor puede ser diferente y comprende además un espacio que separa al menos en dos las partes del núcleo. Dicha membrana de separación consiste esencialmente de una composición de elastómero, siendo la membrana de separación permeable o impermeable a al menos uno de los agentes terapéuticamente activos. La composición de elastómero se selecciona del grupo que consiste en: una composición de elastómero que comprende poli(dimetilsiloxano); una composición de elastómero que comprende un elastómero con base de siloxano que comprende grupos 3,3,3-trifluoropropilo unidos a los átomos de Si de las unidades siloxano; una composición de elastómero que comprende grupos poli(óxido de alquileno), en donde dichos grupos poli(óxido de alquileno) están presentes como injertos terminados con alcoxi o bloques unidos a las unidades de polisiloxano mediante enlaces de silicio-carbono, o como una mezcla de estas formas; y una combinación de al menos dos de los mismos. Las velocidades de liberación de los al menos dos agentes terapéuticos activos son idénticas o diferentes. El sistema de suministro puede ser un implante, un sistema intrauterino, un sistema intracervical o un sistema intravaginal, y el agente terapéuticamente activo puede ser una hormona.
ARP020103244A 2001-08-31 2002-08-29 Un sistema de suministro AR036310A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31597201P 2001-08-31 2001-08-31

Publications (1)

Publication Number Publication Date
AR036310A1 true AR036310A1 (es) 2004-08-25

Family

ID=23226904

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020103244A AR036310A1 (es) 2001-08-31 2002-08-29 Un sistema de suministro

Country Status (14)

Country Link
US (1) US20040247674A1 (es)
EP (1) EP1427390A1 (es)
JP (1) JP2005503389A (es)
KR (1) KR20040036928A (es)
CN (1) CN1289064C (es)
AR (1) AR036310A1 (es)
AU (1) AU2002313517B2 (es)
CA (1) CA2457979A1 (es)
HU (1) HUP0401438A3 (es)
NO (1) NO20041315L (es)
PE (1) PE20030316A1 (es)
PL (1) PL367961A1 (es)
RU (1) RU2302883C2 (es)
WO (1) WO2003017971A1 (es)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005138B2 (en) * 2001-12-21 2006-02-28 Duramed Pharmaceuticals, Inc. Method of systematically delivering SSRIs
US20040181943A1 (en) * 2003-03-18 2004-09-23 Michael Kwiecien Shaving systems
TWI336627B (en) * 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
EP1653931A2 (en) * 2003-07-17 2006-05-10 Banner Pharmacaps, Inc. Controlled release preparations
EP1508343B1 (en) * 2003-08-21 2015-11-04 AddBIO AB Bisphosponate coated implant device and method therefor
JP2008503592A (ja) * 2004-06-22 2008-02-07 グレイストーン メディカル グループ、インコーポレイテッド 徐放性組成物を用いた創傷の治療方法
SI1629844T1 (sl) 2004-07-13 2007-12-31 Bayer Schering Pharma Oy Sistem podaljšanega oddajanja s kontrolirano začetno dozo
US7494665B1 (en) 2004-07-30 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymers containing siloxane monomers
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
US7910126B2 (en) * 2006-03-20 2011-03-22 Teva Women's Health, Inc. Flexible, compressed intravaginal rings, methods of making and using the same, and apparatus for making the same
US8828981B2 (en) 2007-02-06 2014-09-09 George Creasy Progesterone for the treatment or prevention of spontaneous preterm birth
AR066166A1 (es) * 2007-09-21 2009-07-29 Organon Nv Sistema de suministro de droga
EP2057972A1 (en) * 2007-11-07 2009-05-13 N.V. Organon Intrauterine deposit
EP2062568A1 (en) * 2007-11-22 2009-05-27 Bayer Schering Pharma Oy Vaginal delivery system
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
PT2062569E (pt) * 2007-11-22 2011-07-25 Bayer Oy Sistema de administração vaginal
US9314524B2 (en) * 2007-12-31 2016-04-19 Calla Therapeutics Llc Topical formulations of Flucytosine
DE102008006416A1 (de) * 2008-01-28 2009-07-30 Mayer, Thomas, Dr. med. Clindamycin zur Verwendung bei der Behandlung oder Vorbeugung der bakteriellen Vaginosis
EP2359807B1 (en) * 2008-02-04 2017-07-26 Ferring B.V. Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof
EP2140860A1 (en) * 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
FI20080524A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
FI20080523A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
US11992431B2 (en) 2008-09-17 2024-05-28 Bayer Oy Inserter
MX2011002670A (es) 2008-09-17 2011-04-12 Bayer Oy Un insertador.
HUE040045T2 (hu) * 2009-01-29 2019-02-28 Fondazione Irccs Istituto Naz Dei Tumori Méhnyakon belüli eszköz gyógyszerek felszabadítására a méhnyakrák lokoregionális kezelésében
FI20095550A0 (fi) * 2009-05-19 2009-05-19 Bayer Schering Pharma Oy Vaginaalinen antojärjestelmä
FI122579B (fi) 2010-10-29 2012-03-30 Bayer Oy Insertteri
CN102525722A (zh) * 2010-12-30 2012-07-04 辽宁爱母医疗科技有限公司 具有记忆效应的智能型复方孕二烯酮阴道环制剂及其应用
EP2476409A1 (en) * 2011-01-14 2012-07-18 Université Catholique De Louvain Implant comprising a core and a tube encasing the core
WO2012138542A1 (en) * 2011-04-07 2012-10-11 Arstat, Inc. Treatment of menstrual pain and excessive menstrual blood loss by intravaginal administration of a low dose of antifibrinolytic or hemostatic agent in combination with non- steroidal anti-inflammatory drug
US10028858B2 (en) 2011-07-11 2018-07-24 Medicines360 Intrauterine systems, IUD insertion devices, and related methods and kits therefor
DE102012024126A1 (de) 2011-12-20 2013-06-20 Merck Patent Gmbh Flüssigkristallines Medium
AR089765A1 (es) 2012-01-23 2014-09-17 Bayer Oy Un sistema para el suministro de un farmaco
US10154856B2 (en) 2013-02-06 2018-12-18 Mark SILLENDER Therapeutic substance transfer catheter and method
AU2014214538B2 (en) 2013-02-06 2018-11-15 Mark SILLENDER Embryo transfer catheter and method
SE539540C2 (sv) * 2013-09-12 2017-10-10 Qpharma Ab Ett läkemedelsavgivningssystem för en eller flera aktiva beståndsdelar
US9963556B2 (en) * 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
US20160262923A1 (en) * 2013-10-18 2016-09-15 Bayer Oy Intrauterine delivery system
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10772842B2 (en) * 2015-01-09 2020-09-15 Patheon Softgels Inc. Abuse-deterrent opioids
CN106456377A (zh) * 2014-05-30 2017-02-22 纺织品技术股份有限公司 药物递送系统以及相关使用方法
HUE046267T2 (hu) 2015-01-21 2020-02-28 Bayer Oy Nem szteroid gyulladáscsökkentõ (NSAID) és progesztogén vegyületet tartalmazó gyógyszerbeviteli rendszer és elõállítási eljárások
CN108135910B (zh) 2015-05-13 2022-12-02 拜耳股份有限公司 长效药物递送装置及其在避孕中的用途
CN105056376A (zh) * 2015-08-21 2015-11-18 崔尚品 一种治疗宫颈炎和宫颈hpv感染的医疗器械
WO2019094625A1 (en) * 2017-11-09 2019-05-16 Nexien Biopharma, Inc. Methods and compositions for parenteral administration of cannabidiol in the treatment of convulsive disorders
CN110917478B (zh) * 2019-12-10 2020-11-24 河南省肿瘤医院 一种宫颈hpv感染用药物缓释器
US11173291B2 (en) * 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11338119B2 (en) * 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11344526B2 (en) * 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
WO2022029780A1 (en) * 2020-08-06 2022-02-10 Bless Medical Ltd. Intrauterine device for controlled drug release
US20230047191A1 (en) * 2021-08-05 2023-02-16 Celanese Eva Performance Polymers Llc Implantable Medical Device for the Delivery of Bisphosphonate

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996934A (en) * 1971-08-09 1976-12-14 Alza Corporation Medical bandage
US4155991A (en) * 1974-10-18 1979-05-22 Schering Aktiengesellschaft Vaginal ring
DE3040978A1 (de) * 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
US4601893A (en) * 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
US4596576A (en) * 1984-10-12 1986-06-24 Akzo N.V. Release system for two or more active substances
US4666441A (en) * 1985-12-17 1987-05-19 Ciba-Geigy Corporation Multicompartmentalized transdermal patches
US5538736A (en) * 1987-04-28 1996-07-23 Lts Lohmann Therapie-Systeme Gmbh Active substance-containing plaster for the controlled administration of active substances to the skin
DE19975054I2 (de) * 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
US5064422A (en) * 1990-10-18 1991-11-12 Bertek, Inc. Twin patch applicator
US5443461A (en) * 1993-08-31 1995-08-22 Alza Corporation Segmented device for simultaneous delivery of multiple beneficial agents
US5660848A (en) * 1994-11-02 1997-08-26 The Population Council, Center For Biomedical Research Subdermally implantable device
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
CA2291659A1 (fr) * 1997-06-04 1998-12-10 Debio Recherche Pharmaceutique S.A. Implants pour la liberation controlee de principes pharmaceutiquement actifs et procede pour leur fabrication
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US6117442A (en) * 1998-11-12 2000-09-12 Leiras Oy Drug delivery device, especially for the delivery of androgens
US6063395A (en) * 1998-11-12 2000-05-16 Leiras Oy Drug delivery device especially for the delivery of progestins and estrogens
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
US6436428B1 (en) * 2000-03-21 2002-08-20 Enhance Pharmaceuticals, Inc. Device and method for treating urinary incontinence in females

Also Published As

Publication number Publication date
HUP0401438A2 (hu) 2004-11-29
PL367961A1 (en) 2005-03-07
PE20030316A1 (es) 2003-04-03
RU2302883C2 (ru) 2007-07-20
CN1549703A (zh) 2004-11-24
NO20041315L (no) 2004-03-30
AU2002313517B2 (en) 2007-09-06
HUP0401438A3 (en) 2008-04-28
RU2004109575A (ru) 2005-08-20
KR20040036928A (ko) 2004-05-03
CA2457979A1 (en) 2003-03-06
EP1427390A1 (en) 2004-06-16
US20040247674A1 (en) 2004-12-09
WO2003017971A1 (en) 2003-03-06
CN1289064C (zh) 2006-12-13
JP2005503389A (ja) 2005-02-03

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