HUP0104380A2 - Gyógyszerhatóanyag áthatolását szabályozó membrán vagy mátrix - Google Patents

Gyógyszerhatóanyag áthatolását szabályozó membrán vagy mátrix

Info

Publication number
HUP0104380A2
HUP0104380A2 HU0104380A HUP0104380A HUP0104380A2 HU P0104380 A2 HUP0104380 A2 HU P0104380A2 HU 0104380 A HU0104380 A HU 0104380A HU P0104380 A HUP0104380 A HU P0104380A HU P0104380 A2 HUP0104380 A2 HU P0104380A2
Authority
HU
Hungary
Prior art keywords
membrane
matrix
elastomer
siloxane
trifluoropropyl
Prior art date
Application number
HU0104380A
Other languages
English (en)
Inventor
Juha Ala-Sorvari
Harri Jukarainen
Matti Lehtinen
Tommi Markkula
Jarkko Ruohonen
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of HUP0104380A2 publication Critical patent/HUP0104380A2/hu
Publication of HUP0104380A3 publication Critical patent/HUP0104380A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/2036—Silicones; Polysiloxanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Silicon Polymers (AREA)
  • Materials For Medical Uses (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)

Abstract

A találmány membránra vagy mátrixra vonatkozik, amely sziloxánalapúelasztomerből készül, és amely gyógyszerhatóanyagok áthatolásánakszabályozására alkalmas, ahol az említett elasztomerben asziloxánegységek szilíciumatomjaihoz 3,3,3-trifluor-propil-csoportokkapcsolódnak. A találmány tárgyát képezi egy 3,3,3-trifluor-propil-csoport-helyettesítőket tartalmazó sziloxánalapú elasztomerelőállítására alkalmas eljárás is, ahol az elasztomergyógyszerhatóanyag áthatolásának szabályzására használható. Azeljárásnak megfelelően vagy i) egy 3,3,3-trifluor-propil-csoporttalhelyettesített vinil funkciós csoportot tartalmazópolisziloxánkomponenst és egy szilícium-hidrid funkciós csoportottartalmazó térhálósítószert katalizátor jelenlétében térhálósítanak,vagy ii) egy 3,3,3-trifluor-propil-csoporttal helyettesítettpolisziloxánkomponenst peroxidkatalizátor jelenlétében térhálósítanak. Ó
HU0104380A 1998-11-12 1999-10-26 Membrane or matrix for controlling drug permeation HUP0104380A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/190,608 US6056976A (en) 1998-11-12 1998-11-12 Elastomer, its preparation and use
PCT/FI1999/000888 WO2000029464A1 (en) 1998-11-12 1999-10-26 Novel membrane or matrix for controlling drug permeation

Publications (2)

Publication Number Publication Date
HUP0104380A2 true HUP0104380A2 (hu) 2002-03-28
HUP0104380A3 HUP0104380A3 (en) 2003-04-28

Family

ID=22702039

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104380A HUP0104380A3 (en) 1998-11-12 1999-10-26 Membrane or matrix for controlling drug permeation

Country Status (25)

Country Link
US (1) US6056976A (hu)
EP (1) EP1151030A1 (hu)
JP (1) JP2002530447A (hu)
KR (1) KR20010075701A (hu)
CN (1) CN1127535C (hu)
AR (1) AR025815A1 (hu)
AU (1) AU756089B2 (hu)
BG (1) BG105499A (hu)
BR (1) BR9915325A (hu)
CA (1) CA2351091A1 (hu)
CZ (1) CZ291399B6 (hu)
DE (1) DE1151030T1 (hu)
EE (1) EE05528B1 (hu)
HK (1) HK1041895B (hu)
HU (1) HUP0104380A3 (hu)
ID (1) ID29223A (hu)
IL (2) IL142525A0 (hu)
NO (1) NO20012045L (hu)
NZ (1) NZ511215A (hu)
PE (1) PE20001019A1 (hu)
PL (1) PL348115A1 (hu)
RU (1) RU2231531C2 (hu)
SK (1) SK5142001A3 (hu)
WO (1) WO2000029464A1 (hu)
ZA (1) ZA200103297B (hu)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214926B1 (en) * 1999-04-01 2001-04-10 Rhodia Inc. Silicone membranes formed without the use of 1-1-1 trichloroethane
US6436428B1 (en) * 2000-03-21 2002-08-20 Enhance Pharmaceuticals, Inc. Device and method for treating urinary incontinence in females
US6299894B1 (en) 2000-05-10 2001-10-09 Leiras Oy Drug delivery device, especially for the delivery of gestodene
AU2001258442A1 (en) * 2000-05-10 2001-11-20 Leiras Oy Drug delivery device, especially for the delivery of levonorgestrel
US6550480B2 (en) * 2001-01-31 2003-04-22 Numed/Tech Llc Lumen occluders made from thermodynamic materials
EP1438942A1 (en) * 2003-01-17 2004-07-21 Schering Oy An otorhinological drug delivery device
US20050038188A1 (en) * 2003-08-14 2005-02-17 Dongchan Ahn Silicones having improved chemical resistance and curable silicone compositions having improved migration resistance
US20050038183A1 (en) * 2003-08-14 2005-02-17 Dongchan Ahn Silicones having improved surface properties and curable silicone compositions for preparing the silicones
US7045586B2 (en) * 2003-08-14 2006-05-16 Dow Corning Corporation Adhesives having improved chemical resistance and curable silicone compositions for preparing the adhesives
US7862552B2 (en) * 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
US20090168013A1 (en) * 2007-12-27 2009-07-02 Kunzler Jay F Trimethylsilyl-Capped Polysiloxane Macromonomers Containing Polar Fluorinated Side-Chains
SI2359807T1 (sl) 2008-02-04 2017-10-30 Ferring B.V. Monolitni intravaginalni obroč, ki vsebuje progesteron ter postopki za njegovo izdelavo in uporabo
EP2140860A1 (en) 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
US11992431B2 (en) 2008-09-17 2024-05-28 Bayer Oy Inserter
FI20080523A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
FI20080524A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
CA2736020C (en) 2008-09-17 2016-12-06 Bayer Oy An inserter
FI122579B (fi) 2010-10-29 2012-03-30 Bayer Oy Insertteri
US10028858B2 (en) 2011-07-11 2018-07-24 Medicines360 Intrauterine systems, IUD insertion devices, and related methods and kits therefor
TW201350122A (zh) 2012-04-23 2013-12-16 Bayer Pharma AG １８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內用途，包含１８－甲基－１５β，１６β－亞甲基－１９－降－２０－螺氧－４－烯－３－酮的子宮內系統，及其於避孕及婦科治療之用途
KR20150005548A (ko) 2012-04-23 2015-01-14 바이엘 파마 악티엔게젤샤프트 월경과다증의 치료에서의 18-메틸-15β,16β-메틸렌-19-노르-20-스피록스-4-엔-3-온 시스템의 용도, 및 자궁 출혈 장애의 치료를 위한 18-메틸-15β,16β-메틸렌-19-노르-20-스피록스-4-엔-3-온을 함유하는 자궁내 시스템
PE20160534A1 (es) * 2013-10-18 2016-06-15 Bayer Oy Sistema de administracion intrauterina
EP3040388B1 (en) 2014-12-31 2017-08-23 LG Display Co., Ltd. Touch sensitive device comprising electroactive film, display device comprising the same, and method of manufacturing the electroactive film
KR102431597B1 (ko) * 2014-12-31 2022-08-11 엘지디스플레이 주식회사 전기활성 필름을 포함하는 접촉 감응 소자, 이를 포함하는 표시 장치 및 전기활성 필름의 제조 방법
WO2016180764A1 (en) 2015-05-13 2016-11-17 Bayer Oy A long acting drug delivery device and its use in contraception
WO2018202574A1 (en) 2017-05-04 2018-11-08 Bayer Oy Intravaginal drug delivery system, method for manufacturing such system and its use in gynecological therapies and contraception
US11571328B2 (en) 2018-04-09 2023-02-07 Medicines360 IUD insertion devices
US20200261258A1 (en) 2019-02-19 2020-08-20 Medicines360 Devices, systems, methods and kits for insertion and removal of iuds

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3050492A (en) * 1962-08-21 Degrees of twist at indicated centigrade temperature
US3179619A (en) * 1965-04-20 Xow swell, high temperature organosi- loxane rubbeks containing silicon- bonded fluokjnated aliphatic radicals
US3279996A (en) * 1962-08-28 1966-10-18 Jr David M Long Polysiloxane carrier for controlled release of drugs and other agents
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3661833A (en) * 1970-07-09 1972-05-09 Dow Corning Fast curing organosiloxane resins
US3974120A (en) * 1975-05-05 1976-08-10 General Electric Company Fluorosilicone copolymers and process for the preparation thereof
CH657779A5 (de) * 1982-10-05 1986-09-30 Sandoz Ag Galenische zusammensetzungen enthaltend calcitonin.
US4525528A (en) * 1983-10-11 1985-06-25 General Electric Company Peroxide-curable fluorosilicone copolymer compositions
NZ217844A (en) * 1985-10-11 1989-10-27 Sumitomo Pharma A sustained release pharmaceutical composition containing silicone elastomer and an albumin
US5310572A (en) * 1987-02-03 1994-05-10 Dow Corning Corporation Process for forming a coated active agent-containing article
GB8704755D0 (en) * 1987-02-28 1987-04-01 Dow Corning Ltd Pharmaceutical delivery device
FR2643572A1 (fr) * 1988-12-22 1990-08-31 Rhone Poulenc Chimie Procede d'encapsulation de particules par pelliculage au moyen d'un copolymere silicone thermoplastique
JPH07216233A (ja) * 1992-09-21 1995-08-15 Toray Dow Corning Silicone Co Ltd フルオロシリコーンゴム組成物
US5492993A (en) * 1994-02-03 1996-02-20 Dow Corning Corporation Strain-crystallizing poly(methyl(3,3,3-trifluoropropyl)-siloxane) elastomers and methods for making
DE69511180T2 (de) * 1994-06-20 1999-12-23 Dow Corning Verfahren zur Steuerung der Freisetzung einer Wirksubstanz oder eines Arzneistoffs aus einer Silikongummi-Matrix

Also Published As

Publication number Publication date
HK1041895A1 (en) 2002-07-26
CZ20011570A3 (cs) 2001-09-12
NO20012045L (no) 2001-06-28
RU2231531C2 (ru) 2004-06-27
CN1127535C (zh) 2003-11-12
CA2351091A1 (en) 2000-05-25
CN1326478A (zh) 2001-12-12
JP2002530447A (ja) 2002-09-17
EE05528B1 (et) 2012-04-16
IL142525A0 (en) 2002-03-10
NO20012045D0 (no) 2001-04-26
AR025815A1 (es) 2002-12-18
NZ511215A (en) 2002-04-26
PL348115A1 (en) 2002-05-06
BR9915325A (pt) 2001-10-09
EP1151030A1 (en) 2001-11-07
ID29223A (id) 2001-08-16
HUP0104380A3 (en) 2003-04-28
WO2000029464A1 (en) 2000-05-25
BG105499A (bg) 2001-12-29
SK5142001A3 (en) 2001-11-06
PE20001019A1 (es) 2000-10-12
AU1048900A (en) 2000-06-05
EE200100257A (et) 2002-12-16
ZA200103297B (en) 2001-10-25
US6056976A (en) 2000-05-02
IL142525A (en) 2006-07-05
KR20010075701A (ko) 2001-08-09
AU756089B2 (en) 2003-01-02
CZ291399B6 (cs) 2003-02-12
DE1151030T1 (de) 2002-04-04
HK1041895B (zh) 2004-07-23

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Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished