FI107020B - Menetelmä transdermaalisen terapeuttisen laastarin valmistamiseksi - Google Patents

Menetelmä transdermaalisen terapeuttisen laastarin valmistamiseksi Download PDF

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Publication number
FI107020B
FI107020B FI934189A FI934189A FI107020B FI 107020 B FI107020 B FI 107020B FI 934189 A FI934189 A FI 934189A FI 934189 A FI934189 A FI 934189A FI 107020 B FI107020 B FI 107020B
Authority
FI
Finland
Prior art keywords
layer
sensitive adhesive
pressure
drug
drug reservoir
Prior art date
Application number
FI934189A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI934189A0 (fi
FI934189A (fi
Inventor
Thomas Hille
Lothar Deurer
Dieter Anhaeuser
Peter Steinborn
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of FI934189A0 publication Critical patent/FI934189A0/fi
Publication of FI934189A publication Critical patent/FI934189A/fi
Application granted granted Critical
Publication of FI107020B publication Critical patent/FI107020B/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F2013/0296—Apparatus or processes for manufacturing adhesive dressings or bandages for making transdermal patches (chemical processes excluded)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1052—Methods of surface bonding and/or assembly therefor with cutting, punching, tearing or severing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1052—Methods of surface bonding and/or assembly therefor with cutting, punching, tearing or severing
    • Y10T156/108—Flash, trim or excess removal
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1052—Methods of surface bonding and/or assembly therefor with cutting, punching, tearing or severing
    • Y10T156/1084—Methods of surface bonding and/or assembly therefor with cutting, punching, tearing or severing of continuous or running length bonded web
    • Y10T156/1085—One web only
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1089—Methods of surface bonding and/or assembly therefor of discrete laminae to single face of additional lamina
    • Y10T156/1092—All laminae planar and face to face
    • Y10T156/1093—All laminae planar and face to face with covering of discrete laminae with additional lamina
    • Y10T156/1095—Opposed laminae are running length webs
FI934189A 1991-03-27 1993-09-24 Menetelmä transdermaalisen terapeuttisen laastarin valmistamiseksi FI107020B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4110027A DE4110027C2 (de) 1991-03-27 1991-03-27 Verfahren zur Konfektionierung transdermaler therapeutischer Pflaster
DE4110027 1991-03-27
EP9200513 1992-03-09
PCT/EP1992/000513 WO1992017237A1 (de) 1991-03-27 1992-03-09 Transdermales therapeutisches pflaster

Publications (3)

Publication Number Publication Date
FI934189A0 FI934189A0 (fi) 1993-09-24
FI934189A FI934189A (fi) 1993-09-24
FI107020B true FI107020B (fi) 2001-05-31

Family

ID=6428306

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934189A FI107020B (fi) 1991-03-27 1993-09-24 Menetelmä transdermaalisen terapeuttisen laastarin valmistamiseksi

Country Status (26)

Country Link
US (1) US6315854B1 (da)
EP (1) EP0577622B1 (da)
JP (1) JPH0665349B2 (da)
KR (1) KR970006100B1 (da)
AT (1) ATE146365T1 (da)
AU (1) AU657314B2 (da)
CA (1) CA2106374C (da)
CZ (1) CZ281267B6 (da)
DE (2) DE4110027C2 (da)
DK (1) DK0577622T3 (da)
ES (1) ES2098500T3 (da)
FI (1) FI107020B (da)
GR (1) GR3022863T3 (da)
HR (1) HRP930668B1 (da)
HU (1) HU210845B (da)
IE (1) IE78823B1 (da)
IL (1) IL101189A (da)
MY (1) MY106656A (da)
NO (1) NO306849B1 (da)
NZ (1) NZ242127A (da)
PH (1) PH31285A (da)
SI (1) SI9210277B (da)
SK (1) SK278995B6 (da)
WO (1) WO1992017237A1 (da)
YU (1) YU48183B (da)
ZA (1) ZA922190B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4229230C2 (de) * 1992-09-02 1997-01-16 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Pentetrazol als Wirkstoff
DE19547691C1 (de) * 1995-12-20 1997-04-24 Lohmann Therapie Syst Lts Verfahren zur Herstellung transdermaler therapeutischer Pflaster (TTS)
DE19702314C2 (de) * 1997-01-23 2000-12-21 Lohmann Therapie Syst Lts Ablösbare Schutzfolie für wirkstoffhaltige, insbesondere selbstklebende Pflastersysteme
DE19736315A1 (de) * 1997-08-21 1999-02-25 Lohmann Therapie Syst Lts Wirkstoffhaltige Dochtsysteme
DE19738855C2 (de) 1997-09-05 2001-01-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit haftklebender Reservoirschicht und unidirektional elastischer Rückschicht
DE19749525C1 (de) 1997-11-08 1999-06-10 Lohmann Therapie Syst Lts Laserstrahl-Schneideverfahren zum Schneiden von Laminat zur Applikation auf die Haut und Fixiervorrichtung
GB2336310B (en) * 1998-04-14 2003-09-10 Stowic Resources Ltd Method of manufacturing transdermal patches
DE19923427A1 (de) 1999-05-21 2000-11-23 Lohmann Therapie Syst Lts Vorrichtung und Verfahren zur Steigerung der transdermalen Permeation von Arzneistoffen
DE19925338A1 (de) * 1999-06-02 2000-12-07 Lohmann Therapie Syst Lts Substratabschnitte mit erhöhter Lagerstabilität während ihrer Lagerung in Beutelverpackung, sowie Verfahren zu ihrer Herstellung
DE60141596D1 (de) * 2000-10-23 2010-04-29 Euro Celtique Sa Transdermales system zur verabreichung von loratadin und dessen verwendung
GB2414397B (en) * 2004-05-26 2009-03-11 Johnson And Johnson Medical Ltd Self-irrigating wound dressing
CN101232875B (zh) * 2005-06-10 2014-06-25 3M创新有限公司 处理粘合层叠片片段的方法
DE102007006244B4 (de) * 2007-02-08 2012-03-15 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System zur Verabreichung wasserlöslicher Wirkstoffe
ATE485797T1 (de) * 2007-08-21 2010-11-15 Lohmann Therapie Syst Lts Verfahren zum mehrspurigen konfektionieren transdermaler therapeutischer pflaster
DE102010000661A1 (de) * 2010-01-04 2011-07-07 Acino Ag, 83714 Verfahren und Vorrichtung zur Herstellung einer überlappenden Schutzfolie für ein transdermales therapeutisches System
DE102010064358A1 (de) 2010-12-29 2012-07-05 Acino Ag Transdermales Applikationssystem mit überstehender Backingfolie
EP2682113B1 (de) * 2012-07-02 2018-10-31 Luye Pharma AG Verschließen wirkstoffhaltiger Laminate
EP2818159A1 (de) * 2013-06-25 2014-12-31 LTS LOHMANN Therapie-Systeme AG Vorrichtung mit transdermalem therapeutischem System, Positionier- und Penetrationshilfe
EP2921184A1 (de) * 2014-03-19 2015-09-23 LTS LOHMANN Therapie-Systeme AG Überpflaster mit verbesserter Verträglichkeit und einer langen Haftungsdauer und Verfahren zu seiner Herstellung
EP3233492B1 (en) 2014-12-18 2021-11-10 Kindeva Drug Delivery L.P. Methods of handling adhesive laminate patches
CN112402095B (zh) * 2020-11-17 2022-05-31 新领医药技术(深圳)有限公司 一种硫酸镁冷敷贴及其制备工艺

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US2862846A (en) * 1953-11-23 1958-12-02 Johnson & Johnson Method of making plastic strip adhesive bandages
US2703083A (en) * 1955-01-04 1955-03-01 William J Gross Adhesive bandage
US3245855A (en) * 1962-01-18 1966-04-12 Carl B Stenvall Method for making adhesive bandage
CA1192825A (en) * 1980-11-10 1985-09-03 Minnesota Mining And Manufacturing Company Device and method for applying conformable, thin adhesive-coated films
US4725272A (en) 1981-06-29 1988-02-16 Alza Corporation Novel bandage for administering beneficial drug
DE3204582A1 (de) * 1982-02-10 1983-08-25 Hassia Verpackung Gmbh, 6479 Ranstadt Verfahren zur kontinuierlichen herstellung von pflasterpackungen fuer die transdermale verabreichung von medikamenten
US4556441A (en) * 1983-01-24 1985-12-03 Faasse Jr Adrian L Pharmaceutical packaging method
US4704119A (en) * 1983-02-03 1987-11-03 Alza Corporation Method comprising transdermal and buccal treatment of angina
DE3315272C2 (de) * 1983-04-27 1986-03-27 Lohmann Gmbh & Co Kg, 5450 Neuwied Pharmazeutisches Produkt und Verfahren zu seiner Herstellung
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
DE3586707T2 (de) * 1984-10-05 1993-02-11 Hercon Lab System zur transdermalen applikation eines arzneimittels.
US4638043A (en) * 1984-11-13 1987-01-20 Thermedics, Inc. Drug release system
US4614076A (en) * 1985-05-23 1986-09-30 Becton, Dickinson And Company Flexible packaging apparatus and method
DE3770836D1 (de) * 1986-02-14 1991-07-25 Ciba Geigy Ag Dermale und transdermale therapeutische systeme mit musterfoermig aufgetragener klebschicht, sowie verfahren zur dessen herstellung.
DE3634016A1 (de) * 1986-04-17 1987-10-29 Lohmann Gmbh & Co Kg Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung
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DE3714140A1 (de) * 1987-04-28 1988-11-10 Lohmann Therapie Syst Lts Wirkstoffhaltiges pflaster zur kontrollierten verabreichung von wirkstoffen an die haut, seine verwendung sowie verfahren zur gesteuerten verabreichung von wirkstoffen an die haut
DE3743946A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur abgabe von nitroglycerin an die haut, verfahren zu ihrer herstellung sowie ihre verwendung
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US4867821A (en) * 1988-07-11 1989-09-19 Morgan Burton D Process for fabricating self-adhesive bandages
DE3908432A1 (de) * 1989-03-14 1990-09-27 Lohmann Therapie Syst Lts Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung
DE3910543A1 (de) * 1989-04-01 1990-10-11 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung
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US5112618A (en) * 1989-11-01 1992-05-12 Ndm Acquisition Corp. Hydrogel wound dressing product
US5268179A (en) * 1992-02-14 1993-12-07 Ciba-Geigy Corporation Ultrasonically sealed transdermal drug delivery systems

Also Published As

Publication number Publication date
IE920963A1 (en) 1992-10-07
HU9302700D0 (en) 1993-12-28
FI934189A0 (fi) 1993-09-24
JPH0665349B2 (ja) 1994-08-24
KR970006100B1 (ko) 1997-04-23
ES2098500T3 (es) 1997-05-01
ZA922190B (en) 1992-12-30
MY106656A (en) 1995-07-31
EP0577622A1 (de) 1994-01-12
GR3022863T3 (da) 1997-06-30
CA2106374C (en) 1997-03-18
HRP930668A2 (en) 1994-10-31
HRP930668B1 (en) 2001-02-28
YU27792A (sh) 1995-01-31
SI9210277A (en) 1994-06-30
CA2106374A1 (en) 1992-09-28
CZ281267B6 (cs) 1996-07-17
NO933414L (no) 1993-09-24
EP0577622B1 (de) 1996-12-18
WO1992017237A1 (de) 1992-10-15
NO933414D0 (no) 1993-09-24
SK101193A3 (en) 1994-04-06
CZ193293A3 (en) 1994-03-16
AU1353592A (en) 1992-11-02
HUT65961A (en) 1994-08-29
JPH06501185A (ja) 1994-02-10
SK278995B6 (sk) 1998-05-06
PH31285A (en) 1998-07-06
SI9210277B (sl) 2000-10-31
YU48183B (sh) 1997-07-31
DE4110027A1 (de) 1992-10-01
DK0577622T3 (da) 1997-06-16
FI934189A (fi) 1993-09-24
HU210845B (en) 1995-08-28
AU657314B2 (en) 1995-03-09
IL101189A (en) 1995-05-26
NZ242127A (en) 1994-04-27
NO306849B1 (no) 2000-01-03
US6315854B1 (en) 2001-11-13
ATE146365T1 (de) 1997-01-15
IE78823B1 (en) 1998-02-25
DE4110027C2 (de) 1996-08-29
DE59207727D1 (de) 1997-01-30

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Legal Events

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MA Patent expired