FI106306B - Förfarande för framställning av anti-GP-39-antikropp - Google Patents
Förfarande för framställning av anti-GP-39-antikropp Download PDFInfo
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- FI106306B FI106306B FI960978A FI960978A FI106306B FI 106306 B FI106306 B FI 106306B FI 960978 A FI960978 A FI 960978A FI 960978 A FI960978 A FI 960978A FI 106306 B FI106306 B FI 106306B
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/04—Immunostimulants
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
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- A—HUMAN NECESSITIES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11625593A | 1993-09-02 | 1993-09-02 | |
| US11625593 | 1993-09-02 | ||
| US08/232,929 US5869049A (en) | 1993-09-02 | 1994-04-25 | Methods of inducing T cell unresponsiveness to bone marrow with gp39 antagonists |
| US23292994 | 1994-04-25 | ||
| PCT/US1994/009871 WO1995006666A1 (en) | 1993-09-02 | 1994-09-02 | Anti-gp39 antibodies and uses therefor |
| US9409871 | 1994-09-02 |
Publications (3)
| Publication Number | Publication Date |
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| FI960978A0 FI960978A0 (sv) | 1996-03-01 |
| FI960978A FI960978A (sv) | 1996-04-29 |
| FI106306B true FI106306B (sv) | 2001-01-15 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| FI960978A FI106306B (sv) | 1993-09-02 | 1996-03-01 | Förfarande för framställning av anti-GP-39-antikropp |
| FI960980A FI105528B (sv) | 1993-09-02 | 1996-03-01 | Metoder för inducering av antigenspecifik T-celltolerans |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI960980A FI105528B (sv) | 1993-09-02 | 1996-03-01 | Metoder för inducering av antigenspecifik T-celltolerans |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US5747037A (sv) |
| EP (2) | EP0721346B1 (sv) |
| JP (3) | JP2991499B2 (sv) |
| CN (2) | CN1127351C (sv) |
| AT (2) | ATE167062T1 (sv) |
| AU (2) | AU696235B2 (sv) |
| DE (2) | DE69411025T2 (sv) |
| DK (2) | DK0721469T3 (sv) |
| ES (2) | ES2143553T3 (sv) |
| FI (2) | FI106306B (sv) |
| GR (2) | GR3027658T3 (sv) |
| HU (2) | HU220296B (sv) |
| IL (1) | IL110855A (sv) |
| NO (2) | NO321098B1 (sv) |
| NZ (3) | NZ273207A (sv) |
| PT (1) | PT721469E (sv) |
| WO (2) | WO1995006481A1 (sv) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5962406A (en) * | 1991-10-25 | 1999-10-05 | Immunex Corporation | Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same |
| US7070777B1 (en) | 1991-11-15 | 2006-07-04 | The Trustees Of Columbia University In The City Of New York | Method for inhibiting inflammation with an antibody that binds the 5C8 protein |
| US5474771A (en) * | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
| DK0721469T3 (da) * | 1993-09-02 | 2000-05-01 | Dartmouth College | Anti-gp39-antistoffer og anvendelse deraf |
| US5683693A (en) * | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
| US5876950A (en) * | 1995-01-26 | 1999-03-02 | Bristol-Myers Squibb Company | Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy |
| JPH08239324A (ja) * | 1995-03-03 | 1996-09-17 | Fusanori Hamashima | 免疫抑制剤 |
| US7153508B2 (en) | 1995-06-07 | 2006-12-26 | Biogen Idec Inc. | Treatment of B cell lymphoma using anti-CD80 antibodies that do not inhibit the binding of CD80 to CTLA-4 |
| US6113898A (en) | 1995-06-07 | 2000-09-05 | Idec Pharmaceuticals Corporation | Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies |
| US5833987A (en) * | 1995-06-07 | 1998-11-10 | Trustees Of Dartmouth College | Treatment of T cell mediated autoimmune disorders |
| US7175847B1 (en) | 1995-06-07 | 2007-02-13 | Biogen Idec Inc. | Treating intestinal inflammation with anti-CD80 antibodies that do not inhibit CD80 binding to CTLA-4 |
| US6001358A (en) * | 1995-11-07 | 1999-12-14 | Idec Pharmaceuticals Corporation | Humanized antibodies to human gp39, compositions containing thereof |
| US6440418B1 (en) * | 1995-11-07 | 2002-08-27 | Idec Pharmaceuticals Corporation | Methods of treating autoimmune diseases with gp39-specific antibodies |
| US6340459B1 (en) | 1995-12-01 | 2002-01-22 | The Trustees Of Columbia University In The City Of New York | Therapeutic applications for the anti-T-BAM (CD40-L) monoclonal antibody 5C8 in the treatment of reperfusion injury in non-transplant recipients |
| DK0892643T4 (da) * | 1996-03-20 | 2009-12-14 | Bristol Myers Squibb Co | Fremgangsmåder til inhibering af et immunrespons ved blokering af GP39/CD40- og CTLA4/CD28/B7-banerne og præparater til anvendelse derved |
| DE19634159C1 (de) * | 1996-08-23 | 1997-09-25 | Gsf Forschungszentrum Umwelt | Induktion einer Tumorimmunität durch Injektion von Hybridzellen |
| AU4352997A (en) * | 1996-08-30 | 1998-03-19 | Genzyme Corporation | Inhibition of primary and/or secondary immune response to repeat adenoviral vector administration using cd40l specific antibodies |
| DE69837322T2 (de) * | 1997-01-10 | 2007-11-22 | Biogen Idec Ma Inc., Cambridge | Verfahren zur therapeutischen verabreichung von anti-cd40l-mitteln |
| US6428782B1 (en) * | 1997-05-23 | 2002-08-06 | Hadasit Medical Research Services And Development Ltd. | Non-myeloablative tolerogenic treatment |
| US7553487B2 (en) * | 1998-12-14 | 2009-06-30 | Genetics Institute, Llc | Method and compositions for treating asthma |
| PT1141286E (pt) | 1998-12-14 | 2007-01-31 | Genetics Inst Llc | Cadeia de receptores de citocina |
| AU2845400A (en) * | 1998-12-24 | 2000-07-31 | Phairson Medical Inc. | Treatment and prevention of immune rejection reactions |
| WO2000072882A1 (fr) * | 1999-06-01 | 2000-12-07 | Eisai Co., Ltd. | Agents prophylactiques du purpura thrombocytopenique idiopathique |
| WO2001000679A2 (en) * | 1999-06-29 | 2001-01-04 | University Of Massachusetts | Methods for inducing t cell non-responsiveness to a tissue or organ graft |
| US20020028178A1 (en) * | 2000-07-12 | 2002-03-07 | Nabil Hanna | Treatment of B cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications |
| EP1262194A4 (en) * | 2000-03-06 | 2003-05-07 | Eisai Co Ltd | HEALING AND PREVENTIVE AGENTS FOR THE ANTIPHOSPHOLIPID-ANTIBODY SYNDROME |
| WO2001079555A2 (en) | 2000-04-14 | 2001-10-25 | Millennium Pharmaceuticals, Inc. | Roles of jak/stat family members in tolerance induction |
| CN101130078A (zh) * | 2000-04-25 | 2008-02-27 | 拜奥根Idec公司 | 瑞图希单抗的鞘内施用,用于中枢神经系统淋巴瘤的治疗 |
| CA2408691A1 (en) | 2000-05-12 | 2001-11-22 | Beth Israel Deaconess Medical Center, Inc. | Compositions and methods for achieving immune suppression |
| US20030012781A1 (en) * | 2000-06-06 | 2003-01-16 | Anderson Darrell | Non-agonistic antibodies to human gp39, compositions containing, and therapeutic use thereof |
| US20040022787A1 (en) | 2000-07-03 | 2004-02-05 | Robert Cohen | Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID |
| MY137552A (en) | 2000-07-03 | 2009-02-27 | Bristol Myers Squibb Co | Methods for treating rheumatic diseases using a soluble ctla4 molecule |
| WO2002040050A1 (en) * | 2000-11-14 | 2002-05-23 | The University Of Louisville Research Foundation, Inc. | Non-lethal methods for conditioning a recipient for bone marrow transplantation |
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- 1994-09-02 EP EP94926677A patent/EP0721346B1/en not_active Revoked
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- 1994-09-02 HU HU9700522A patent/HU218610B/hu not_active IP Right Cessation
- 1994-09-02 DK DK94926677T patent/DK0721346T3/da active
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