FI101622B1 - Menetelmä terapeuttisesti aktiivisten N-(4-piperidyyli)(dihydrobentsofuraani)karboksamidi- tai N-(4-piperidyyli)(dihydro-2H-bentsopyraani)karboksamidijohdannaisten valmistamiseksi ja välituote - Google Patents
Menetelmä terapeuttisesti aktiivisten N-(4-piperidyyli)(dihydrobentsofuraani)karboksamidi- tai N-(4-piperidyyli)(dihydro-2H-bentsopyraani)karboksamidijohdannaisten valmistamiseksi ja välituoteInfo
- Publication number
- FI101622B1 FI101622B1 FI911096A FI911096A FI101622B1 FI 101622 B1 FI101622 B1 FI 101622B1 FI 911096 A FI911096 A FI 911096A FI 911096 A FI911096 A FI 911096A FI 101622 B1 FI101622 B1 FI 101622B1
- Authority
- FI
- Finland
- Prior art keywords
- aryl
- alkyl
- piperidyl
- alk
- cycloalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909005014A GB9005014D0 (en) | 1990-03-06 | 1990-03-06 | N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives |
GB9005014 | 1990-03-06 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI911096A0 FI911096A0 (fi) | 1991-03-05 |
FI911096A FI911096A (fi) | 1991-09-07 |
FI101622B FI101622B (fi) | 1998-07-31 |
FI101622B1 true FI101622B1 (fi) | 1998-07-31 |
Family
ID=10672103
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI911096A FI101622B1 (fi) | 1990-03-06 | 1991-03-05 | Menetelmä terapeuttisesti aktiivisten N-(4-piperidyyli)(dihydrobentsofuraani)karboksamidi- tai N-(4-piperidyyli)(dihydro-2H-bentsopyraani)karboksamidijohdannaisten valmistamiseksi ja välituote |
Country Status (39)
Country | Link |
---|---|
US (2) | US5185335A (fi) |
EP (1) | EP0445862B1 (fi) |
JP (1) | JP2601566B2 (fi) |
KR (1) | KR0177521B1 (fi) |
CN (1) | CN1038936C (fi) |
AT (1) | ATE191912T1 (fi) |
AU (1) | AU636012B2 (fi) |
BG (1) | BG60381B1 (fi) |
CA (1) | CA2037575C (fi) |
CY (1) | CY2235B1 (fi) |
CZ (1) | CZ286617B6 (fi) |
DE (1) | DE69132119T2 (fi) |
DK (1) | DK0445862T3 (fi) |
ES (1) | ES2147175T3 (fi) |
FI (1) | FI101622B1 (fi) |
GB (1) | GB9005014D0 (fi) |
GR (1) | GR3033461T3 (fi) |
HK (1) | HK1010727A1 (fi) |
HR (1) | HRP930483B1 (fi) |
HU (2) | HU221627B1 (fi) |
IE (1) | IE910710A1 (fi) |
IL (1) | IL97018A (fi) |
LT (1) | LT3708B (fi) |
LV (1) | LV10085B (fi) |
MA (1) | MA22076A1 (fi) |
MY (1) | MY108831A (fi) |
NO (1) | NO177424C (fi) |
NZ (1) | NZ237189A (fi) |
PL (6) | PL168356B1 (fi) |
PT (1) | PT96937B (fi) |
RU (1) | RU2070884C1 (fi) |
SG (1) | SG47482A1 (fi) |
SI (1) | SI9110396B (fi) |
SK (2) | SK282407B6 (fi) |
TN (1) | TNSN91010A1 (fi) |
UA (1) | UA25969A1 (fi) |
YU (1) | YU48854B (fi) |
ZA (1) | ZA911611B (fi) |
ZW (1) | ZW2391A1 (fi) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2674849B1 (fr) * | 1991-04-02 | 1994-12-23 | Logeais Labor Jacques | Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique. |
CA2118812C (en) * | 1991-09-12 | 2006-01-17 | Francis David King | 5-ht4 receptor antagonists |
EP0625149A1 (en) * | 1992-02-06 | 1994-11-23 | Smithkline Beecham Plc | Benzopyran, benzothiopyran and benzofuran derivatives as 5-ht4 antagonists |
US5595872A (en) * | 1992-03-06 | 1997-01-21 | Bristol-Myers Squibb Company | Nucleic acids encoding microsomal trigyceride transfer protein |
GB9219163D0 (en) * | 1992-09-10 | 1992-10-28 | Smithkline Beecham Plc | Pharmaceuticals |
MX9306311A (es) * | 1992-10-13 | 1994-04-29 | Smithkline Beecham Plc | Compuestos antagonistas del receptor de 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que los contienen |
AU5150393A (en) * | 1992-10-13 | 1994-05-09 | Smithkline Beecham Plc | Heterocyclic -esters or -amides used as 5-ht4 receptor antagonists |
TW294595B (fi) * | 1992-11-20 | 1997-01-01 | Janssen Pharmaceutica Nv | |
GB9301660D0 (en) * | 1993-01-28 | 1993-03-17 | Smithkline Beecham Plc | Pharmaceuticals |
US5739135A (en) * | 1993-09-03 | 1998-04-14 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
US5864039A (en) * | 1994-03-30 | 1999-01-26 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compounds and use thereof as medicaments |
JPH0820586A (ja) * | 1994-07-05 | 1996-01-23 | Sanwa Kagaku Kenkyusho Co Ltd | 1−アザビシクロ[3.3.0]オクタン誘導体、その塩及び製法並びに用途 |
GB9418326D0 (en) * | 1994-09-12 | 1994-11-02 | Lilly Industries Ltd | Pharmaceutical compounds |
JPH0873463A (ja) | 1994-07-05 | 1996-03-19 | Sanwa Kagaku Kenkyusho Co Ltd | ベンゾピランカルボキサミド誘導体、その塩及び製法並びに用途 |
AU702846B2 (en) * | 1994-09-27 | 1999-03-04 | Janssen Pharmaceutica N.V. | Phenyl-oxo-alkyl-(4-piperidinyl)benzoate derivatives |
WO1996010027A1 (en) * | 1994-09-27 | 1996-04-04 | Janssen Pharmaceutica N.V. | N-substituted piperidinyl bicyclic benzoate derivatives |
TW490465B (en) * | 1994-11-24 | 2002-06-11 | Janssen Pharmaceutica Nv | Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof |
US6096763A (en) * | 1995-02-23 | 2000-08-01 | Merck & Co., Inc. | α1a adrenergic receptor antagonists |
TW360653B (en) * | 1995-03-01 | 1999-06-11 | Janssen Pharmaceutica Nv | A oxadiazole compound having colon motility stimulating properties, its preparation process and its pharmaceutical composition |
GB9507882D0 (en) * | 1995-04-18 | 1995-05-31 | Pharmacia Spa | Substituted dihydrobenzofuran derivatives as 5-ht4 agonists |
GB2308362A (en) * | 1995-12-19 | 1997-06-25 | Lilly Industries Ltd | Pharmaceutical indole derivatives |
TW402591B (en) | 1997-07-11 | 2000-08-21 | Janssen Pharmaceutica Nv | Monocyclic benzamides of 3- or 4-substituted 4-(aminomethyl)-piperidine derivatives |
US6294555B1 (en) | 1998-04-28 | 2001-09-25 | Dainippon Pharmaceutical Co., Ltd. | 1-[(1-Substituted-4-piperidinyl)methyl]-4-piperidine derivative, process for producing the same, medicinal compositions containing the same and intermediates of these compounds |
SK17212000A3 (sk) * | 1998-05-14 | 2001-05-10 | Egis Gy�Gyszergy�R Rt. | Benzofuránové deriváty, farmaceutické kompozície ich obsahujúce a spôsob prípravy aktívnej zložky |
EP1112270B1 (en) | 1998-09-10 | 2007-03-21 | F. Hoffmann-La Roche Ag | Dihydrobenzodioxine carboxamide and ketone derivatives as 5-ht4 receptor antagonists |
NZ511117A (en) * | 1998-11-23 | 2002-11-26 | Janssen Pharmaceutica Nv | Use of prucalopride for the manufacture of a medicament for the treatment of dyspepsia |
TW592709B (en) * | 1999-04-29 | 2004-06-21 | Janssen Pharmaceutica Nv | Prucalopride oral solution |
SE9902987D0 (sv) | 1999-08-24 | 1999-08-24 | Astra Pharma Prod | Novel compounds |
CN1288730A (zh) * | 1999-09-07 | 2001-03-28 | 麦克内尔-Ppc股份有限公司 | 轻泻组合物 |
GB0011838D0 (en) * | 2000-05-17 | 2000-07-05 | Astrazeneca Ab | Chemical compounds |
GB0104050D0 (en) | 2001-02-19 | 2001-04-04 | Astrazeneca Ab | Chemical compounds |
GB0107228D0 (en) | 2001-03-22 | 2001-05-16 | Astrazeneca Ab | Chemical compounds |
SE0103818D0 (sv) | 2001-11-15 | 2001-11-15 | Astrazeneca Ab | Chemical compounds |
RU2301806C2 (ru) * | 2002-01-16 | 2007-06-27 | Янссен Фармацевтика Н.В. | Прукалоприд-n-оксид |
TW200409637A (en) * | 2002-06-26 | 2004-06-16 | Glaxo Group Ltd | Compounds |
SE0301369D0 (sv) | 2003-05-09 | 2003-05-09 | Astrazeneca Ab | Chemical compounds |
DE10349113A1 (de) * | 2003-10-17 | 2005-05-12 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Aminocrotonylverbindungen |
GB0525661D0 (en) * | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Novel compounds |
SI3091011T1 (en) * | 2006-04-07 | 2018-06-29 | Vertex Pharmaceuticals Incorporated | Modulators of ATP conveyor belt conveyors |
CN102477002B (zh) * | 2010-11-26 | 2015-04-15 | 苏州凯达生物医药技术有限公司 | 3-氨基-2,2-双甲基丙酰胺的制备方法 |
JP5980236B2 (ja) | 2011-02-25 | 2016-08-31 | ユーハン・コーポレイションYUHAN Corporation | ジアミノピリミジン誘導体及びその製造方法 |
GB201103397D0 (fi) | 2011-02-28 | 2011-04-13 | Shire Movetis N V | |
KR101256908B1 (ko) * | 2011-04-28 | 2013-04-23 | (주)에이치비메디컬스 | 주름제거용 충전체 |
CN102295594B (zh) * | 2011-07-12 | 2016-01-20 | 上海医药工业研究院 | 4-n-取代-1-(3-甲氧基丙基)-4-哌啶胺类化合物及制备和应用 |
CA2845039A1 (en) | 2011-08-18 | 2013-02-21 | Shire Ag | Combinations of a 5-ht4 receptor agonist and a pde4 inhibitor for use in therapy |
KR101657616B1 (ko) | 2013-05-24 | 2016-09-19 | 주식회사유한양행 | 피리미딘 고리를 포함하는 바이사이클릭 유도체 및 그의 제조방법 |
EP3413891B1 (en) * | 2016-02-11 | 2024-01-03 | Symed Labs Limited | Processes for the preparation of highly pure prucalopride succinate |
CN110963999B (zh) * | 2019-11-27 | 2021-05-11 | 广东东阳光药业有限公司 | 2,3-二氢苯并呋喃酰胺衍生物及其用途 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4186135A (en) * | 1976-08-04 | 1980-01-29 | Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France | Substituted 2,3-alkylene bis (oxy) benzamides and derivatives and method of preparation |
FR2396757A2 (fr) * | 1977-07-08 | 1979-02-02 | Ile De France | Nouveaux 2,3-alkylene bis (oxy) benzamides substitues, leurs derives et leurs procedes de preparation |
FR2493848B2 (fr) * | 1980-11-07 | 1986-05-16 | Delalande Sa | Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique |
EP0069481A1 (en) * | 1981-06-17 | 1983-01-12 | Beecham Group Plc | Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them |
EP0068700A1 (en) * | 1981-06-29 | 1983-01-05 | Beecham Group Plc | Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them |
US4962115A (en) * | 1981-10-01 | 1990-10-09 | Janssen Pharmaceutica N.V. | Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
CA1183847A (en) | 1981-10-01 | 1985-03-12 | Georges Van Daele | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
NZ203861A (en) * | 1982-04-14 | 1986-07-11 | Beecham Group Plc | Bicyclic heterocyclic compounds and pharmaceutical compositions containing such |
US4525356A (en) * | 1982-11-02 | 1985-06-25 | Hokuriku Pharmaceutical Co., Ltd. | N-substituted flavone-8-carboxamides |
EP0135545A1 (en) * | 1983-02-19 | 1985-04-03 | Beecham Group Plc | Azabicycloalkyl benzamide and anilide derivatives |
JPS59186969A (ja) * | 1983-04-08 | 1984-10-23 | Yoshitomi Pharmaceut Ind Ltd | ベンゾフラン−およびベンゾピランカルボキサミド誘導体 |
CA1297877C (en) * | 1983-12-22 | 1992-03-24 | Daniel Lednicer | Benzofurancarboxamides useful as antiemetic or antipsychotic agents |
US4888353A (en) * | 1986-02-28 | 1989-12-19 | Erbamont, Inc. | Carboxamides useful as antiemetic or antipsychotic agents |
US4808624A (en) * | 1984-06-28 | 1989-02-28 | Bristol-Myers Company | Pharmacologically active substituted benzamides |
GB8519707D0 (en) * | 1985-08-06 | 1985-09-11 | Fordonal Sa | Chemical compounds |
GB8527052D0 (en) * | 1985-11-02 | 1985-12-04 | Beecham Group Plc | Compounds |
FR2593504B1 (fr) | 1986-01-30 | 1988-12-09 | Ile De France | Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques |
US4772459A (en) * | 1986-09-09 | 1988-09-20 | Erbamont, Inc. | Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein |
US4906643A (en) * | 1987-07-17 | 1990-03-06 | Janssen Pharmaceutica N.V. | Substituted N-(3-hydroxy-4-piperidinyl)benzamides as gastrointestinal agents |
US5130312A (en) * | 1987-07-17 | 1992-07-14 | Janssen Pharmaceutica N.V. | Substituted N-(3-hydroxy-4-piperidinyl)benzamides |
NZ225152A (en) | 1987-07-17 | 1990-04-26 | Janssen Pharmaceutica Nv | Heterocyclically substituted piperidinyl benzamides as pharmaceuticals |
GB8718346D0 (en) * | 1987-08-03 | 1987-09-09 | Fordonal Sa | Substituted benzamides |
ZA886585B (en) * | 1987-09-08 | 1990-05-30 | Lilly Co Eli | Specific 5-ht,antagonists |
US5041454A (en) * | 1987-09-25 | 1991-08-20 | Janssen Pharmaceutica N.V. | Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides |
US4975439A (en) * | 1987-09-25 | 1990-12-04 | Janssen Pharmaceutical N.V. | Novel substituted N-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides |
CA1317940C (en) | 1987-09-25 | 1993-05-18 | Georges H. P. Van Daele | Substituted n-(1-alkyl-3-hydroxy-4-piperidinyl)benzamides |
US4863921A (en) * | 1988-04-27 | 1989-09-05 | Rorer Pharmaceutical Corporation | Dibenzofurancarboxamides and their pharmaceutical compositions and methods |
US5374637A (en) * | 1989-03-22 | 1994-12-20 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran or dihydrobenzodioxin)carboxamide derivatives |
-
1990
- 1990-03-06 GB GB909005014A patent/GB9005014D0/en active Pending
-
1991
- 1991-02-04 US US07/650,328 patent/US5185335A/en not_active Expired - Lifetime
- 1991-02-21 NZ NZ237189A patent/NZ237189A/xx unknown
- 1991-02-22 DK DK91200382T patent/DK0445862T3/da active
- 1991-02-22 ES ES91200382T patent/ES2147175T3/es not_active Expired - Lifetime
- 1991-02-22 CZ CS1991460A patent/CZ286617B6/cs not_active IP Right Cessation
- 1991-02-22 DE DE69132119T patent/DE69132119T2/de not_active Expired - Lifetime
- 1991-02-22 SG SG1996002170A patent/SG47482A1/en unknown
- 1991-02-22 AT AT91200382T patent/ATE191912T1/de not_active IP Right Cessation
- 1991-02-22 EP EP91200382A patent/EP0445862B1/en not_active Expired - Lifetime
- 1991-02-22 SK SK1623-98A patent/SK282407B6/sk not_active IP Right Cessation
- 1991-02-22 SK SK460-91A patent/SK282406B6/sk not_active IP Right Cessation
- 1991-02-28 JP JP3058048A patent/JP2601566B2/ja not_active Expired - Lifetime
- 1991-03-02 KR KR1019910003440A patent/KR0177521B1/ko not_active IP Right Cessation
- 1991-03-04 IE IE071091A patent/IE910710A1/en not_active IP Right Cessation
- 1991-03-04 MY MYPI91000336A patent/MY108831A/en unknown
- 1991-03-04 AU AU72079/91A patent/AU636012B2/en not_active Expired
- 1991-03-05 CA CA002037575A patent/CA2037575C/en not_active Expired - Lifetime
- 1991-03-05 BG BG93979A patent/BG60381B1/bg unknown
- 1991-03-05 RU SU914894778A patent/RU2070884C1/ru active
- 1991-03-05 ZA ZA911611A patent/ZA911611B/xx unknown
- 1991-03-05 UA UA4894778A patent/UA25969A1/uk unknown
- 1991-03-05 NO NO910863A patent/NO177424C/no not_active IP Right Cessation
- 1991-03-05 PT PT96937A patent/PT96937B/pt not_active IP Right Cessation
- 1991-03-05 ZW ZW23/91A patent/ZW2391A1/xx unknown
- 1991-03-05 HU HU9100706A patent/HU221627B1/hu unknown
- 1991-03-05 FI FI911096A patent/FI101622B1/fi active
- 1991-03-06 SI SI9110396A patent/SI9110396B/sl unknown
- 1991-03-06 PL PL91308055A patent/PL168356B1/pl unknown
- 1991-03-06 PL PL91289323A patent/PL168811B1/pl unknown
- 1991-03-06 MA MA22349A patent/MA22076A1/fr unknown
- 1991-03-06 PL PL91308053A patent/PL168686B1/pl unknown
- 1991-03-06 CN CN91101360A patent/CN1038936C/zh not_active Expired - Lifetime
- 1991-03-06 YU YU39691A patent/YU48854B/sh unknown
- 1991-03-06 TN TNTNSN91010A patent/TNSN91010A1/fr unknown
- 1991-03-06 PL PL91309550A patent/PL169238B1/pl unknown
- 1991-03-06 PL PL91308054A patent/PL168693B1/pl unknown
- 1991-03-06 PL PL91308052A patent/PL168384B1/pl unknown
- 1991-10-24 IL IL9701891A patent/IL97018A/en not_active IP Right Cessation
-
1992
- 1992-11-17 US US07/977,314 patent/US5262418A/en not_active Expired - Lifetime
- 1992-11-27 LV LVP-92-232A patent/LV10085B/en unknown
-
1993
- 1993-03-23 HR HR930483A patent/HRP930483B1/xx not_active IP Right Cessation
- 1993-08-10 LT LTIP846A patent/LT3708B/lt not_active IP Right Cessation
-
1995
- 1995-06-16 HU HU95P/P00241P patent/HU211350A9/hu unknown
-
1998
- 1998-10-27 HK HK98111558A patent/HK1010727A1/xx not_active IP Right Cessation
-
2000
- 2000-05-19 GR GR20000401151T patent/GR3033461T3/el not_active IP Right Cessation
- 2000-06-16 CY CY0000025A patent/CY2235B1/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI101622B1 (fi) | Menetelmä terapeuttisesti aktiivisten N-(4-piperidyyli)(dihydrobentsofuraani)karboksamidi- tai N-(4-piperidyyli)(dihydro-2H-bentsopyraani)karboksamidijohdannaisten valmistamiseksi ja välituote | |
MY117557A (en) | 1-(1,2-disubstituted piperidinyl)-4- substituted piperidine derivatives | |
MY121852A (en) | 4-(aminoethyl)-piperidine benzamides for treating gastrointestinal disorders | |
NZ508910A (en) | Di-substituted piperazine or piperidine derivatives useful as muscarinic antagonists | |
MY117680A (en) | 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)- piperidine derivatives | |
NZ333513A (en) | 1,4-di-substituted piperidines and medicaments useful as muscarinic antagonists | |
NO166180C (no) | Analogifremgangsmaate for fremstilling av ace-inhiberende forbindelser. | |
BG104717A (en) | Water soluble azoles as broad-spectrum antifungals | |
AR006754A1 (es) | Derivados de quinoxalina utiles en terapia | |
MX9701165A (es) | Triazolinonas sustituidas como agentes para la proteccion de plantas. | |
MY101878A (en) | 1,3,4-thiadiazole |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Transfer of assignment of patent |
Owner name: MOVETIS N.V. Free format text: MOVETIS N.V. |