ES8609309A1 - Un nuevo procedimiento para la preparacion de nuevos derivados. de carbazolona. - Google Patents

Un nuevo procedimiento para la preparacion de nuevos derivados. de carbazolona.

Info

Publication number
ES8609309A1
ES8609309A1 ES539852A ES539852A ES8609309A1 ES 8609309 A1 ES8609309 A1 ES 8609309A1 ES 539852 A ES539852 A ES 539852A ES 539852 A ES539852 A ES 539852A ES 8609309 A1 ES8609309 A1 ES 8609309A1
Authority
ES
Spain
Prior art keywords
phenyl
hydrogen
imidazolylmethyl
carbazol
tetrahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES539852A
Other languages
English (en)
Spanish (es)
Other versions
ES539852A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848401888A external-priority patent/GB8401888D0/en
Priority claimed from GB848425959A external-priority patent/GB8425959D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES539852A0 publication Critical patent/ES539852A0/es
Publication of ES8609309A1 publication Critical patent/ES8609309A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES539852A 1984-01-25 1985-01-25 Un nuevo procedimiento para la preparacion de nuevos derivados. de carbazolona. Expired ES8609309A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848401888A GB8401888D0 (en) 1984-01-25 1984-01-25 Heterocyclic compounds
GB848425959A GB8425959D0 (en) 1984-10-15 1984-10-15 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
ES539852A0 ES539852A0 (es) 1986-07-16
ES8609309A1 true ES8609309A1 (es) 1986-07-16

Family

ID=26287221

Family Applications (3)

Application Number Title Priority Date Filing Date
ES539852A Expired ES8609309A1 (es) 1984-01-25 1985-01-25 Un nuevo procedimiento para la preparacion de nuevos derivados. de carbazolona.
ES548430A Expired ES8708224A1 (es) 1984-01-25 1985-10-31 Un procedimiento para la preparacion de nuevos derivados de carbazolona
ES556101A Expired ES8801247A1 (es) 1984-01-25 1986-06-16 Un procedimiento para la preparacion de nuevos derivados de carbazolona

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES548430A Expired ES8708224A1 (es) 1984-01-25 1985-10-31 Un procedimiento para la preparacion de nuevos derivados de carbazolona
ES556101A Expired ES8801247A1 (es) 1984-01-25 1986-06-16 Un procedimiento para la preparacion de nuevos derivados de carbazolona

Country Status (29)

Country Link
KR (1) KR920003064B1 (cs)
AT (1) AT392276B (cs)
AU (1) AU579132B2 (cs)
BE (1) BE901576A (cs)
CA (1) CA1252793A (cs)
CH (1) CH664152A5 (cs)
CY (1) CY1479A (cs)
CZ (1) CZ404391A3 (cs)
DE (2) DE19375046I2 (cs)
DK (1) DK169521B1 (cs)
ES (3) ES8609309A1 (cs)
FI (1) FI84349C (cs)
FR (1) FR2561244B1 (cs)
GB (1) GB2153821B (cs)
GR (1) GR850219B (cs)
HK (1) HK33189A (cs)
HU (1) HU193592B (cs)
IE (1) IE57809B1 (cs)
IL (1) IL74165A (cs)
IT (1) IT1182150B (cs)
LU (2) LU88268I2 (cs)
NL (2) NL190373C (cs)
NO (2) NO164025C (cs)
NZ (1) NZ210940A (cs)
PH (1) PH22672A (cs)
PT (1) PT79890B (cs)
SE (1) SE460359B (cs)
SG (1) SG7089G (cs)
SK (1) SK404391A3 (cs)

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DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
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JPH01258673A (ja) * 1987-10-22 1989-10-16 Glaxo Group Ltd ケトン誘導体
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JPH0256485A (ja) * 1988-04-27 1990-02-26 Glaxo Group Ltd ラクタム誘導体
GB8812636D0 (en) * 1988-05-27 1988-06-29 Glaxo Group Ltd Chemical compounds
US5173493A (en) * 1988-09-27 1992-12-22 Fujisawa Pharmaceutical Company, Ltd. Pyridoindole derivatives and processes for preparation thereof
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
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FR2639944B1 (fr) * 1988-12-06 1991-01-18 Adir Nouveaux derives de l'indole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2004911A1 (en) * 1988-12-22 1990-06-22 Mitsuaki Ohta 4,5,6,7-tetrahydrobenzimidazole derivatives
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
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GB8914804D0 (en) * 1989-06-28 1989-08-16 Glaxo Group Ltd Process
US5276050A (en) * 1989-08-01 1994-01-04 Glaxo Group Limited Medicaments
GB8917557D0 (en) * 1989-08-01 1989-09-13 Glaxo Group Ltd Medicaments
US5126343A (en) * 1989-09-11 1992-06-30 G. D. Searle & Co. N-azabicyclo [3.3.0]octane amides of aromatic acids
GB2236751B (en) 1989-10-14 1993-04-28 Wyeth John & Brother Ltd Heterocyclic compounds
GB8928837D0 (en) * 1989-12-21 1990-02-28 Beecham Group Plc Pharmaceuticals
US5187166A (en) * 1990-07-31 1993-02-16 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives and their use as antiemetics
WO1993000074A1 (en) * 1991-06-26 1993-01-07 Sepracor, Inc. Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron
JPH05310732A (ja) * 1992-03-12 1993-11-22 Mitsubishi Kasei Corp シンノリン−3−カルボン酸誘導体
ES2043535B1 (es) * 1992-03-13 1994-08-01 Vita Invest Sa Procedimiento para la obtencion de la 1,2,3,9-tetrahidro-9-metil-3-(2-metil-1h-imidazol-1-il)metil*-4h-carbazol-4-ona.
HU212934B (en) 1992-10-14 1996-12-30 Richter Gedeon Vegyeszet Process for producing novel alkoxalylated carbazolone derivatives
CA2106642C (en) * 1992-10-14 2005-08-16 Peter Bod Carbazolone derivatives and process for preparing the same
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GB9310756D0 (en) * 1993-05-25 1993-07-14 Glaxo Lab Sa Compositions
GB2327348A (en) * 1994-06-28 1999-01-27 Kenneth Francis Prendergast Pharmaceutical use of ondansetron
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EP1499623B1 (en) 2002-04-29 2007-06-13 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-¬(2-methyl-1h-imidazol-1-yl)methyl|-4h-carbazol-4-one
FI6164U1 (fi) * 2003-01-09 2004-03-15 Synthon Bv Ondansetronmuotoja
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US3740404A (en) * 1969-05-09 1973-06-19 American Cyanamid Co Piperidinomethylenedihydrocarbazolones
EP0191562B1 (en) * 1985-01-23 1991-07-10 Glaxo Group Limited Tetrahydrocarbazolone derivatives

Also Published As

Publication number Publication date
IE57809B1 (en) 1993-04-21
FR2561244A1 (fr) 1985-09-20
AT392276B (de) 1991-02-25
PT79890A (en) 1985-02-01
IL74165A (en) 1988-11-15
LU85743A1 (fr) 1986-08-04
CH664152A5 (fr) 1988-02-15
GB2153821B (en) 1988-01-20
CY1479A (en) 1989-07-21
DE3502508C2 (cs) 1990-05-03
NO850300L (no) 1985-07-26
KR850005439A (ko) 1985-08-26
SE8500368D0 (sv) 1985-01-25
GR850219B (cs) 1985-05-23
HU193592B (en) 1987-11-30
DK169521B1 (da) 1994-11-21
PH22672A (en) 1988-11-14
FI84349B (fi) 1991-08-15
SE8500368L (sv) 1985-07-26
DE3502508A1 (de) 1985-08-14
ES556101A0 (es) 1987-12-16
IT1182150B (it) 1987-09-30
BE901576A (fr) 1985-07-25
AU579132B2 (en) 1988-11-17
IE850187L (en) 1985-07-25
PT79890B (en) 1987-02-03
ES539852A0 (es) 1986-07-16
FI850323A0 (fi) 1985-01-25
ES8708224A1 (es) 1987-10-01
KR920003064B1 (ko) 1992-04-13
NL8500202A (nl) 1985-08-16
GB8501889D0 (en) 1985-02-27
SG7089G (en) 1989-06-09
LU88268I2 (cs) 1994-02-03
CA1252793A (en) 1989-04-18
ATA20485A (de) 1990-08-15
NZ210940A (en) 1989-08-29
HK33189A (en) 1989-04-28
NO1994022I1 (no) 1994-11-09
IT8547600A0 (it) 1985-01-25
NL940009I1 (nl) 1994-07-18
FI84349C (fi) 1991-11-25
GB2153821A (en) 1985-08-29
NO164025B (no) 1990-05-14
DK35785A (da) 1985-07-26
HUT37784A (en) 1986-02-28
DK35785D0 (da) 1985-01-25
SE460359B (sv) 1989-10-02
SK277923B6 (en) 1995-08-09
NL190373B (nl) 1993-09-01
FR2561244B1 (fr) 1988-03-04
ES8801247A1 (es) 1987-12-16
AU3809785A (en) 1985-08-01
NL190373C (nl) 1994-02-01
NO164025C (no) 1990-08-22
NL940009I2 (nl) 1999-05-03
CZ404391A3 (en) 1993-04-14
SK404391A3 (en) 1995-08-09
FI850323L (fi) 1985-07-26
DE19375046I2 (de) 2002-10-10
ES548430A0 (es) 1987-10-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060425