DK0437030T3 - Anvendelse af 4-substituerede imidazoler til nedsættelse af det intraoculære tryk - Google Patents

Anvendelse af 4-substituerede imidazoler til nedsættelse af det intraoculære tryk

Info

Publication number
DK0437030T3
DK0437030T3 DK90312327.1T DK90312327T DK0437030T3 DK 0437030 T3 DK0437030 T3 DK 0437030T3 DK 90312327 T DK90312327 T DK 90312327T DK 0437030 T3 DK0437030 T3 DK 0437030T3
Authority
DK
Denmark
Prior art keywords
intraocular pressure
substituted imidazoles
reduce intraocular
chr3
glaucoma
Prior art date
Application number
DK90312327.1T
Other languages
English (en)
Inventor
Raimo Virtanen
Risto Lammintausta
Arto Karjalainen
Ewen Macdonald
Arto Urtti
Thomas Yorio
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898925618A external-priority patent/GB8925618D0/en
Priority claimed from GB898928288A external-priority patent/GB8928288D0/en
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Application granted granted Critical
Publication of DK0437030T3 publication Critical patent/DK0437030T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
DK90312327.1T 1989-11-13 1990-11-12 Anvendelse af 4-substituerede imidazoler til nedsættelse af det intraoculære tryk DK0437030T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898925618A GB8925618D0 (en) 1989-11-13 1989-11-13 Compositions and their use in lowering intraocular pressur
GB898928288A GB8928288D0 (en) 1989-12-14 1989-12-14 Compositions and their use in lowering intraocular pressure

Publications (1)

Publication Number Publication Date
DK0437030T3 true DK0437030T3 (da) 1994-05-16

Family

ID=26296200

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90312327.1T DK0437030T3 (da) 1989-11-13 1990-11-12 Anvendelse af 4-substituerede imidazoler til nedsættelse af det intraoculære tryk

Country Status (12)

Country Link
US (1) US5304569A (da)
EP (1) EP0437030B1 (da)
JP (1) JP3005035B2 (da)
AT (1) ATE104145T1 (da)
AU (1) AU624031B2 (da)
CA (1) CA2029657C (da)
DE (1) DE69008142T2 (da)
DK (1) DK0437030T3 (da)
ES (1) ES2051479T3 (da)
HU (1) HU207443B (da)
IE (1) IE64064B1 (da)
NZ (1) NZ236034A (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2256135B (en) * 1991-05-31 1995-01-18 Orion Yhtymae Oy Transdermal administration of 4-substituted imidazoles
GB9111732D0 (en) * 1991-05-31 1991-07-24 Orion Yhtymae Oy The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs
US5629345A (en) * 1993-07-23 1997-05-13 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) * 1993-07-23 1999-10-12 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US20100203165A1 (en) 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of disorders or conditions of the eye
US8952011B2 (en) 2008-08-01 2015-02-10 Eye Therapies Llc Compositions and methods for the treatment of nasal conditions
WO2010014552A1 (en) 2008-08-01 2010-02-04 Alpha Synergy Development, Inc. Vasoconstriction compositions and methods of use
US8987270B2 (en) 2009-07-27 2015-03-24 Eye Therapies Llc Formulations of selective alpha-2 agonists and methods of use thereof
CA2782872A1 (en) * 2009-12-17 2011-06-23 Alpha Synergy Development, Inc. Compositions and methods for ophthalmic delivery of nasal decongestants
US20120202863A1 (en) * 2011-02-03 2012-08-09 Gerald Horn Compositions and methods for treatment of glaucoma
US8445526B2 (en) 2011-02-03 2013-05-21 Glaucoma & Nasal Therapies Llc Compositions and methods for treatment of glaucoma
US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
US8242158B1 (en) 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
EP2809300A1 (en) 2012-02-02 2014-12-10 Glaucoma & Nasal Therapies LLC Compositions and methods for treatment of glaucoma
US8999938B2 (en) 2013-06-21 2015-04-07 Gnt Llc Ophthalmic lipophilic drug delivery vehicle formulations
CA2924233C (en) 2013-10-07 2018-10-23 Teikoku Pharma Usa, Inc. Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions
CN110585173A (zh) 2013-10-07 2019-12-20 帝国制药美国公司 右旋美托咪啶经皮递送装置及其使用方法
WO2015054061A1 (en) 2013-10-07 2015-04-16 Teikoku Pharma Usa, Inc. Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine
US9717796B1 (en) 2016-04-20 2017-08-01 Slypharma, Llc Heat sterilizeable, premixed, ready to use dexmedetomidine solution packaged in a flexible plastic container
US11160791B2 (en) 2018-11-01 2021-11-02 Medefil, Inc. Dexmedetomidine injection premix formulation in ready to use (RTU) bags

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2069481B (en) * 1980-02-13 1983-07-27 Farmos Oy Substituted imidazole derivatives
CA1201066A (en) * 1981-11-20 1986-02-25 Alcon Laboratories, Inc. N-¬3,5-dichloro-4-(2-imidazolidinylideneamino)- phenyl|-acetamide solutions for lowering intraocular pressure
FR2549049B1 (fr) * 1983-07-13 1986-06-20 Chauvin Blache Lab Nouvelles amidines, leur procede de preparation et leur application therapeutique

Also Published As

Publication number Publication date
AU624031B2 (en) 1992-05-28
CA2029657A1 (en) 1991-05-14
AU6652390A (en) 1991-05-16
HUT56351A (en) 1991-08-28
IE64064B1 (en) 1995-07-12
EP0437030B1 (en) 1994-04-13
ATE104145T1 (de) 1994-04-15
IE904069A1 (en) 1991-05-22
EP0437030A3 (en) 1991-10-30
US5304569A (en) 1994-04-19
HU207443B (en) 1993-04-28
CA2029657C (en) 2002-06-18
DE69008142D1 (de) 1994-05-19
JPH03170423A (ja) 1991-07-24
DE69008142T2 (de) 1994-07-21
JP3005035B2 (ja) 2000-01-31
HU907099D0 (en) 1991-05-28
EP0437030A2 (en) 1991-07-17
ES2051479T3 (es) 1994-06-16
NZ236034A (en) 1993-03-26

Similar Documents

Publication Publication Date Title
DK0437030T3 (da) Anvendelse af 4-substituerede imidazoler til nedsættelse af det intraoculære tryk
DK9185D0 (da) Dihydropyridazinonderivater og fremgangsmaade til fremstilling deraf
AU538424B2 (en) Piperazino phenylindane
EP0354777A3 (en) 3-(4-piperidine)-5-(2-sulfonylaminoethyl) indole derivatives
FI920023A0 (fi) Heteroarylpiperazinfoereningar som antipsykotiska aemnen.
PL309874A1 (en) Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
NO161564C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive beta-carbolin-3-oxadiazolylderivater.
FI944823A (fi) Galantamiinijohdannaisia, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeaineissa
MX9206930A (es) Nuevos compuestos
DK0420224T3 (da) Anthihepatopatisk middel
DK0556813T3 (da) Amfotere tricykliske forbindelser som antihistaminske og antiallergiske midler
DK0489379T3 (da) 5-Amino-5,6,7,8-tetrahydroquinoliner og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendels
IT1313583B1 (it) Derivati 2-amminotetralinici per la terapia del glaucoma.
ATE79259T1 (de) Prophylaktische und heilende zusammensetzung enthaltende eine 8-chlorbenzothiazepin-verbindung und dessen verwendung.
DK0952157T3 (da) 9a, 11b-dehydroderivater af 9-oxim-3-keto-6-0-methylerythromycin
DK105183D0 (da) Fremgangsmade til fremstilling af 1,4-diaminocyclitolderivater
DE3772850D1 (de) Thiadiazinon-derivate.