ES8506270A1 - Un procedimiento para preparar compuestos analogos de la 7-oxabicicloheptano-prostaglandina - Google Patents

Un procedimiento para preparar compuestos analogos de la 7-oxabicicloheptano-prostaglandina

Info

Publication number
ES8506270A1
ES8506270A1 ES530548A ES530548A ES8506270A1 ES 8506270 A1 ES8506270 A1 ES 8506270A1 ES 530548 A ES530548 A ES 530548A ES 530548 A ES530548 A ES 530548A ES 8506270 A1 ES8506270 A1 ES 8506270A1
Authority
ES
Spain
Prior art keywords
prostaglandin analogs
oxabicicloheptano
alkyl
formula
substituted prostaglandin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530548A
Other languages
English (en)
Spanish (es)
Other versions
ES530548A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/474,913 external-priority patent/US4474803A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of ES530548A0 publication Critical patent/ES530548A0/es
Publication of ES8506270A1 publication Critical patent/ES8506270A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES530548A 1983-03-14 1984-03-13 Un procedimiento para preparar compuestos analogos de la 7-oxabicicloheptano-prostaglandina Expired ES8506270A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/474,913 US4474803A (en) 1983-03-14 1983-03-14 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction
US52332083A 1983-08-15 1983-08-15

Publications (2)

Publication Number Publication Date
ES530548A0 ES530548A0 (es) 1985-07-01
ES8506270A1 true ES8506270A1 (es) 1985-07-01

Family

ID=27044617

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530548A Expired ES8506270A1 (es) 1983-03-14 1984-03-13 Un procedimiento para preparar compuestos analogos de la 7-oxabicicloheptano-prostaglandina

Country Status (24)

Country Link
KR (1) KR840009085A (enrdf_load_stackoverflow)
AT (1) AT383600B (enrdf_load_stackoverflow)
AU (1) AU567919B2 (enrdf_load_stackoverflow)
CA (1) CA1256887A (enrdf_load_stackoverflow)
CH (1) CH658247A5 (enrdf_load_stackoverflow)
DD (1) DD216932A5 (enrdf_load_stackoverflow)
DE (1) DE3409124A1 (enrdf_load_stackoverflow)
DK (1) DK155584A (enrdf_load_stackoverflow)
ES (1) ES8506270A1 (enrdf_load_stackoverflow)
FI (1) FI841008L (enrdf_load_stackoverflow)
FR (1) FR2542743B1 (enrdf_load_stackoverflow)
GB (1) GB2136428B (enrdf_load_stackoverflow)
GR (1) GR79881B (enrdf_load_stackoverflow)
HU (1) HU190530B (enrdf_load_stackoverflow)
IE (1) IE57027B1 (enrdf_load_stackoverflow)
IL (1) IL71184A0 (enrdf_load_stackoverflow)
IT (1) IT1173442B (enrdf_load_stackoverflow)
LU (1) LU85249A1 (enrdf_load_stackoverflow)
NL (1) NL8400797A (enrdf_load_stackoverflow)
NO (1) NO840960L (enrdf_load_stackoverflow)
NZ (1) NZ207361A (enrdf_load_stackoverflow)
PL (1) PL246663A1 (enrdf_load_stackoverflow)
PT (1) PT78242B (enrdf_load_stackoverflow)
SE (1) SE8401398L (enrdf_load_stackoverflow)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513103A (en) * 1983-10-21 1985-04-23 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4560698A (en) * 1984-06-04 1985-12-24 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment in thrombolytic disease
US4661506A (en) * 1984-11-30 1987-04-28 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted ox prostaglandin analogs
US4588743A (en) * 1985-01-22 1986-05-13 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4607049A (en) * 1985-04-22 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease
US4608386A (en) * 1985-04-26 1986-08-26 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases
US4611006A (en) * 1985-06-28 1986-09-09 E. R. Squibb & Sons, Inc. 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease
US4654356A (en) * 1985-08-01 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs
US4673685A (en) * 1986-07-23 1987-06-16 E. R. Squibb & Sons, Inc. Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
ZA829068B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
DE3280020D1 (en) * 1981-12-23 1989-12-21 Nat Res Dev Prostaglandins
US4549030A (en) * 1982-12-13 1985-10-22 The Upjohn Company Organic compounds and process
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease

Also Published As

Publication number Publication date
CH658247A5 (fr) 1986-10-31
FI841008A7 (fi) 1984-09-15
AT383600B (de) 1987-07-27
PT78242B (en) 1986-05-27
IT1173442B (it) 1987-06-24
GB8406100D0 (en) 1984-04-11
HUT34179A (en) 1985-02-28
ES530548A0 (es) 1985-07-01
PT78242A (en) 1984-04-01
SE8401398L (sv) 1984-09-15
KR840009085A (ko) 1984-12-24
DD216932A5 (de) 1985-01-02
NL8400797A (nl) 1984-10-01
IL71184A0 (en) 1984-06-29
NO840960L (no) 1984-09-17
FI841008L (fi) 1984-09-15
FI841008A0 (fi) 1984-03-13
CA1256887A (en) 1989-07-04
AU2523584A (en) 1984-09-20
DK155584D0 (da) 1984-03-13
DE3409124A1 (de) 1984-09-27
IT8420049A0 (it) 1984-03-14
HU190530B (en) 1986-09-29
GB2136428B (en) 1986-09-10
LU85249A1 (fr) 1984-11-14
NZ207361A (en) 1986-12-05
SE8401398D0 (sv) 1984-03-13
AU567919B2 (en) 1987-12-10
DK155584A (da) 1984-09-15
IE840525L (en) 1984-09-14
GB2136428A (en) 1984-09-19
FR2542743B1 (fr) 1987-10-30
PL246663A1 (en) 1985-03-26
ATA83484A (de) 1986-12-15
IE57027B1 (en) 1992-03-25
GR79881B (enrdf_load_stackoverflow) 1984-10-31
FR2542743A1 (fr) 1984-09-21

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