ES8507527A1 - Procedimiento para producir derivados de tiatriazina - Google Patents

Procedimiento para producir derivados de tiatriazina

Info

Publication number
ES8507527A1
ES8507527A1 ES532486A ES532486A ES8507527A1 ES 8507527 A1 ES8507527 A1 ES 8507527A1 ES 532486 A ES532486 A ES 532486A ES 532486 A ES532486 A ES 532486A ES 8507527 A1 ES8507527 A1 ES 8507527A1
Authority
ES
Spain
Prior art keywords
thiatriazine
thiatriazine derivatives
derivatives
new
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532486A
Other languages
English (en)
Other versions
ES532486A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis UK Holdings Ltd
Original Assignee
Hoechst UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst UK Ltd filed Critical Hoechst UK Ltd
Publication of ES8507527A1 publication Critical patent/ES8507527A1/es
Publication of ES532486A0 publication Critical patent/ES532486A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
    • C07C335/42—Sulfonylthioureas; Sulfonylisothioureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE TIATRIAZINA Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE A, X, R3 Y R4 PUEDEN SER VARIOS RADICALES; M VALE 2 O 3; N, 0 O 1; Y P, 1 O 2.CONSISTE EN LA REACCION DE UNA 1,2,4,6-TIATRIAZINA DE FORMULA (II); CON UN AMINOTIOL DE FORMULA HXA-(CH2)M-NH2, EN LAS QUE L1 PUEDE SER VARIOS RADICALES, RA3 ES LO MISMO QUE R3 A EXCEPCION DE HIDROGENO, XA ES OXIGENO O AZUFRE, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I); SEGUIDA DEL TRATAMIENTO DEL PRODUCTO FORMADO CON UN COMPUESTO DE FORMULA A-(CH2)N1-L3, EN LA QUE A ES EL MISMO QUE EN LA FORMULA (I), N1 VALE 1 Y L3 ES UN GRUPO ELIMINABLE.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTAGONISTA H-2 DE LA HISTAMINA.
ES532486A 1982-09-28 1984-05-14 Procedimiento para producir derivados de tiatriazina Granted ES532486A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8227614 1982-09-28

Publications (2)

Publication Number Publication Date
ES8507527A1 true ES8507527A1 (es) 1985-09-01
ES532486A0 ES532486A0 (es) 1985-09-01

Family

ID=10533205

Family Applications (3)

Application Number Title Priority Date Filing Date
ES525943A Expired ES8504753A1 (es) 1982-09-28 1983-09-26 Procedimiento para producir derivados de tiatriazina
ES532485A Expired ES8600262A1 (es) 1982-09-28 1984-05-14 Procedimiento para producir derivados de tiatriazina
ES532486A Granted ES532486A0 (es) 1982-09-28 1984-05-14 Procedimiento para producir derivados de tiatriazina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES525943A Expired ES8504753A1 (es) 1982-09-28 1983-09-26 Procedimiento para producir derivados de tiatriazina
ES532485A Expired ES8600262A1 (es) 1982-09-28 1984-05-14 Procedimiento para producir derivados de tiatriazina

Country Status (15)

Country Link
EP (1) EP0104611A3 (es)
JP (1) JPS5978174A (es)
KR (1) KR840006226A (es)
AU (1) AU1962583A (es)
DK (1) DK442183A (es)
ES (3) ES8504753A1 (es)
FI (1) FI833445A (es)
GB (1) GB2129426B (es)
HU (1) HU192964B (es)
IL (1) IL69820A0 (es)
MA (1) MA19907A1 (es)
NO (1) NO833478L (es)
NZ (1) NZ205732A (es)
PT (1) PT77402B (es)
ZA (1) ZA837186B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4497810A (en) * 1983-10-14 1985-02-05 Merck & Co., Inc. Thiatriazine dioxides as gastric anti-secretory agents
EP0156286A3 (en) * 1984-03-27 1986-08-20 Hoechst Uk Limited Thiatrizine derivatives
US4595683A (en) * 1984-04-27 1986-06-17 William H. Rorer, Inc. 3- and 5-[bicyclic ether or bicyclic alkylene thioether]alkylene amino thiatriazines, and their pharmaceutical uses
US4704388A (en) * 1984-10-23 1987-11-03 Rorer Pharmaceutical Corporation 3- And 5-(bicyclic ether or bicyclic alkylene thioether)alkylene amino thiatriazines, and their pharmaceutical uses
US4742055A (en) * 1984-04-27 1988-05-03 Rorer Pharmaceutical Corporation 3- and 5-amino thiatriazines, and their pharmaceutical uses
GB8419460D0 (en) * 1984-07-31 1984-09-05 Hoechst Uk Ltd 4-substituted-1 2 4 6-thiatriazine derivatives
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them

Also Published As

Publication number Publication date
AU1962583A (en) 1984-04-05
DK442183D0 (da) 1983-09-27
ES525943A0 (es) 1985-04-16
ES8504753A1 (es) 1985-04-16
GB2129426A (en) 1984-05-16
EP0104611A3 (en) 1985-06-12
DK442183A (da) 1984-03-29
MA19907A1 (fr) 1984-04-01
FI833445A (fi) 1984-03-29
GB2129426B (en) 1987-05-28
KR840006226A (ko) 1984-11-22
PT77402B (en) 1986-04-18
EP0104611A2 (en) 1984-04-04
NO833478L (no) 1984-03-29
PT77402A (en) 1983-10-01
JPS5978174A (ja) 1984-05-04
ZA837186B (en) 1984-05-30
ES532486A0 (es) 1985-09-01
ES532485A0 (es) 1985-10-01
IL69820A0 (en) 1983-12-30
GB8325762D0 (en) 1983-10-26
HU192964B (en) 1987-08-28
FI833445A0 (fi) 1983-09-26
ES8600262A1 (es) 1985-10-01
NZ205732A (en) 1986-10-08

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