ES8706637A1 - Un procedimiento para preparar derivados de piridina - Google Patents

Un procedimiento para preparar derivados de piridina

Info

Publication number
ES8706637A1
ES8706637A1 ES554311A ES554311A ES8706637A1 ES 8706637 A1 ES8706637 A1 ES 8706637A1 ES 554311 A ES554311 A ES 554311A ES 554311 A ES554311 A ES 554311A ES 8706637 A1 ES8706637 A1 ES 8706637A1
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
compositions containing
processes
preparation
pyridine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554311A
Other languages
English (en)
Other versions
ES554311A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES8706637A1 publication Critical patent/ES8706637A1/es
Publication of ES554311A0 publication Critical patent/ES554311A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

METODO DE PREPARAR DERIVADOS DE PIRIDINA. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), PARA OBTENER DERIVADOS DE PIRIDINA DE FORMULA (I) DONDE R ES H O ALQUILO DE C 1 A 4; Y ES OXIGENO O AZUFRE, Y SI Y ES UN ATOMO DE AZUFRE, Z ES FENILO OPCIONALMENTE SUSTITUIDO CON UNO O MAS HALOGENO(S) Y/O GRUPO(S) ALQUILO QUE TIENE(N) DE C 1 A 4; B ES UN GRUPO -CH2-CH2-N(R ELEVADO A 1, R ELEVADO A 2), DONDE R ELEVADO A 1 Y R ELEVADO A 2 SON H, ALQUILO DE C 1 A 4 O ALQUILFENILO DE C 1 A 4 EN EL RESTO ALQUILO; A ES HIDROGENO; Y D ES HIDROXILO, HALOGENO Y OTROS. TIENEN APLICACIONES FARMACEUTICAS POR SUS PROPIEDADES ANALGESICAS. *FORMULA*
ES554311A 1984-10-05 1986-04-24 Un procedimiento para preparar derivados de piridina Expired ES8706637A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU843777A HU194830B (en) 1984-10-05 1984-10-05 Process for the production of derivatives of piridine

Publications (2)

Publication Number Publication Date
ES8706637A1 true ES8706637A1 (es) 1987-07-01
ES554311A0 ES554311A0 (es) 1987-07-01

Family

ID=10965443

Family Applications (3)

Application Number Title Priority Date Filing Date
ES547603A Expired ES8705391A1 (es) 1984-10-05 1985-10-04 Un procedimiento para preparar derivados de piridina
ES554311A Expired ES8706637A1 (es) 1984-10-05 1986-04-24 Un procedimiento para preparar derivados de piridina
ES554310A Expired ES8706636A1 (es) 1984-10-05 1986-04-24 Un procedimiento para preparar derivados de piridina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES547603A Expired ES8705391A1 (es) 1984-10-05 1985-10-04 Un procedimiento para preparar derivados de piridina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES554310A Expired ES8706636A1 (es) 1984-10-05 1986-04-24 Un procedimiento para preparar derivados de piridina

Country Status (22)

Country Link
US (1) US4624959A (es)
EP (1) EP0177054B1 (es)
JP (1) JPS6191173A (es)
KR (1) KR860003225A (es)
CN (1) CN85107279A (es)
AT (1) ATE40687T1 (es)
AU (1) AU580096B2 (es)
DD (1) DD238230A5 (es)
DE (1) DE3568164D1 (es)
DK (1) DK455185A (es)
ES (3) ES8705391A1 (es)
FI (1) FI853868L (es)
GR (1) GR852408B (es)
HU (1) HU194830B (es)
IL (1) IL76578A (es)
IN (1) IN162569B (es)
NO (1) NO853937L (es)
PH (1) PH21375A (es)
PL (1) PL147097B1 (es)
PT (1) PT81257B (es)
YU (1) YU158285A (es)
ZA (1) ZA857677B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59201461A (ja) * 1983-04-28 1984-11-15 Toshiba Corp 読み出し専用半導体記憶装置およびその製造方法
HU192875B (en) * 1984-10-05 1987-07-28 Richter Gedeon Vegyeszet Process for preparing 2-pyridinethiol derivatives
US5028716A (en) * 1989-01-30 1991-07-02 Taisho Pharmaceutical Co., Ltd. 3,5-diamino-1,2,4-triazole derivatives
CA2286862A1 (en) * 1997-04-11 1998-10-22 David Mendel Combinatorial libraries of peptidomimetic aminothioether acids
AR029289A1 (es) 2000-07-05 2003-06-18 Ishihara Sangyo Kaisha Derivado de benzoilpiridina o su sal, fungicida que lo contiene como un ingrediente activo, su proceso de produccion e intermediario para producirlo

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT238200B (de) * 1962-03-27 1965-01-25 Degussa Verfahren zur Herstellung von neuen Pyridinderivaten
US4000285A (en) * 1975-04-03 1976-12-28 Smithkline Corporation 2,3-bis-(3-acyl-2-thioureido)-pyridines
US4260620A (en) * 1979-10-26 1981-04-07 Ciba-Geigy Corporation 2-Pyridinecarboxylic acids
JPS5798262A (en) * 1980-12-10 1982-06-18 Yoshitomi Pharmaceut Ind Ltd Pyridine derivative
US4563895A (en) * 1984-08-20 1986-01-14 Aluminum Company Of America Apparatus and method for ultrasonic detection of inclusions in molten metals

Also Published As

Publication number Publication date
PL147097B1 (en) 1989-04-29
HU194830B (en) 1988-03-28
GR852408B (es) 1986-02-04
AU4833085A (en) 1986-04-10
PH21375A (en) 1987-10-15
ES8706636A1 (es) 1987-07-01
KR860003225A (ko) 1986-05-21
PT81257B (en) 1987-03-23
FI853868A0 (fi) 1985-10-04
NO853937L (no) 1986-04-07
IL76578A0 (en) 1986-02-28
ATE40687T1 (de) 1989-02-15
US4624959A (en) 1986-11-25
AU580096B2 (en) 1988-12-22
DE3568164D1 (en) 1989-03-16
DD238230A5 (de) 1986-08-13
ES547603A0 (es) 1987-05-01
ZA857677B (en) 1986-06-25
DK455185D0 (da) 1985-10-04
ES554311A0 (es) 1987-07-01
EP0177054B1 (de) 1989-02-08
FI853868L (fi) 1986-04-06
ES8705391A1 (es) 1987-05-01
PT81257A (en) 1985-11-01
ES554310A0 (es) 1987-07-01
DK455185A (da) 1986-04-06
EP0177054A1 (de) 1986-04-09
HUT38908A (en) 1986-07-28
YU158285A (en) 1988-04-30
IL76578A (en) 1989-03-31
JPS6191173A (ja) 1986-05-09
PL255642A1 (en) 1987-10-05
IN162569B (es) 1988-06-11
CN85107279A (zh) 1986-09-17

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