AT383600B - Verfahren zur herstellung von neuen durch 7-oxabicycloheptan substituierten prostaglandin-analogen - Google Patents

Verfahren zur herstellung von neuen durch 7-oxabicycloheptan substituierten prostaglandin-analogen

Info

Publication number
AT383600B
AT383600B AT0083484A AT83484A AT383600B AT 383600 B AT383600 B AT 383600B AT 0083484 A AT0083484 A AT 0083484A AT 83484 A AT83484 A AT 83484A AT 383600 B AT383600 B AT 383600B
Authority
AT
Austria
Prior art keywords
oxabicycloheptane
producing new
prostaglandin analogs
analogs substituted
new prostaglandin
Prior art date
Application number
AT0083484A
Other languages
German (de)
English (en)
Other versions
ATA83484A (de
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/474,913 external-priority patent/US4474803A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of ATA83484A publication Critical patent/ATA83484A/de
Application granted granted Critical
Publication of AT383600B publication Critical patent/AT383600B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT0083484A 1983-03-14 1984-03-13 Verfahren zur herstellung von neuen durch 7-oxabicycloheptan substituierten prostaglandin-analogen AT383600B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/474,913 US4474803A (en) 1983-03-14 1983-03-14 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction
US52332083A 1983-08-15 1983-08-15

Publications (2)

Publication Number Publication Date
ATA83484A ATA83484A (de) 1986-12-15
AT383600B true AT383600B (de) 1987-07-27

Family

ID=27044617

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0083484A AT383600B (de) 1983-03-14 1984-03-13 Verfahren zur herstellung von neuen durch 7-oxabicycloheptan substituierten prostaglandin-analogen

Country Status (24)

Country Link
KR (1) KR840009085A (enrdf_load_stackoverflow)
AT (1) AT383600B (enrdf_load_stackoverflow)
AU (1) AU567919B2 (enrdf_load_stackoverflow)
CA (1) CA1256887A (enrdf_load_stackoverflow)
CH (1) CH658247A5 (enrdf_load_stackoverflow)
DD (1) DD216932A5 (enrdf_load_stackoverflow)
DE (1) DE3409124A1 (enrdf_load_stackoverflow)
DK (1) DK155584A (enrdf_load_stackoverflow)
ES (1) ES530548A0 (enrdf_load_stackoverflow)
FI (1) FI841008L (enrdf_load_stackoverflow)
FR (1) FR2542743B1 (enrdf_load_stackoverflow)
GB (1) GB2136428B (enrdf_load_stackoverflow)
GR (1) GR79881B (enrdf_load_stackoverflow)
HU (1) HU190530B (enrdf_load_stackoverflow)
IE (1) IE57027B1 (enrdf_load_stackoverflow)
IL (1) IL71184A0 (enrdf_load_stackoverflow)
IT (1) IT1173442B (enrdf_load_stackoverflow)
LU (1) LU85249A1 (enrdf_load_stackoverflow)
NL (1) NL8400797A (enrdf_load_stackoverflow)
NO (1) NO840960L (enrdf_load_stackoverflow)
NZ (1) NZ207361A (enrdf_load_stackoverflow)
PL (1) PL246663A1 (enrdf_load_stackoverflow)
PT (1) PT78242B (enrdf_load_stackoverflow)
SE (1) SE8401398L (enrdf_load_stackoverflow)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513103A (en) * 1983-10-21 1985-04-23 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4560698A (en) * 1984-06-04 1985-12-24 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment in thrombolytic disease
US4661506A (en) * 1984-11-30 1987-04-28 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted ox prostaglandin analogs
US4588743A (en) * 1985-01-22 1986-05-13 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4607049A (en) * 1985-04-22 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease
US4608386A (en) * 1985-04-26 1986-08-26 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases
US4611006A (en) * 1985-06-28 1986-09-09 E. R. Squibb & Sons, Inc. 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease
US4654356A (en) * 1985-08-01 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs
US4673685A (en) * 1986-07-23 1987-06-16 E. R. Squibb & Sons, Inc. Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0113561A2 (en) * 1982-12-13 1984-07-18 The Upjohn Company Prostaglandin intermediates, their synthesis and their conversion to prostaglandins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
ZA829068B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
JPS58502148A (ja) * 1981-12-23 1983-12-15 ナシヨナル　リサ−チ　デイベロツプメント　コ−ポレイシヨン プロスタグランジン
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0113561A2 (en) * 1982-12-13 1984-07-18 The Upjohn Company Prostaglandin intermediates, their synthesis and their conversion to prostaglandins

Also Published As

Publication number Publication date
FR2542743A1 (fr) 1984-09-21
FI841008A7 (fi) 1984-09-15
GB2136428B (en) 1986-09-10
FI841008L (fi) 1984-09-15
GB8406100D0 (en) 1984-04-11
PT78242A (en) 1984-04-01
IE57027B1 (en) 1992-03-25
GR79881B (enrdf_load_stackoverflow) 1984-10-31
CH658247A5 (fr) 1986-10-31
IT8420049A0 (it) 1984-03-14
NL8400797A (nl) 1984-10-01
SE8401398D0 (sv) 1984-03-13
HUT34179A (en) 1985-02-28
DK155584A (da) 1984-09-15
AU567919B2 (en) 1987-12-10
SE8401398L (sv) 1984-09-15
IL71184A0 (en) 1984-06-29
ES8506270A1 (es) 1985-07-01
HU190530B (en) 1986-09-29
GB2136428A (en) 1984-09-19
DE3409124A1 (de) 1984-09-27
ES530548A0 (es) 1985-07-01
KR840009085A (ko) 1984-12-24
IE840525L (en) 1984-09-14
FR2542743B1 (fr) 1987-10-30
AU2523584A (en) 1984-09-20
FI841008A0 (fi) 1984-03-13
PL246663A1 (en) 1985-03-26
NO840960L (no) 1984-09-17
DD216932A5 (de) 1985-01-02
IT1173442B (it) 1987-06-24
CA1256887A (en) 1989-07-04
NZ207361A (en) 1986-12-05
LU85249A1 (fr) 1984-11-14
ATA83484A (de) 1986-12-15
PT78242B (en) 1986-05-27
DK155584D0 (da) 1984-03-13

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee