CH658247A5 - Analogues de la prostaglandine substitues au 7-oxabicycloheptane. - Google Patents

Analogues de la prostaglandine substitues au 7-oxabicycloheptane. Download PDF

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Publication number
CH658247A5
CH658247A5 CH1244/84A CH124484A CH658247A5 CH 658247 A5 CH658247 A5 CH 658247A5 CH 1244/84 A CH1244/84 A CH 1244/84A CH 124484 A CH124484 A CH 124484A CH 658247 A5 CH658247 A5 CH 658247A5
Authority
CH
Switzerland
Prior art keywords
acid
hept
heptenoic
oxabicyclo
procedure
Prior art date
Application number
CH1244/84A
Other languages
English (en)
French (fr)
Inventor
Steven Edward Hall
Martin Frederick Haslanger
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/474,913 external-priority patent/US4474803A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of CH658247A5 publication Critical patent/CH658247A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CH1244/84A 1983-03-14 1984-03-13 Analogues de la prostaglandine substitues au 7-oxabicycloheptane. CH658247A5 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/474,913 US4474803A (en) 1983-03-14 1983-03-14 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction
US52332083A 1983-08-15 1983-08-15

Publications (1)

Publication Number Publication Date
CH658247A5 true CH658247A5 (fr) 1986-10-31

Family

ID=27044617

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1244/84A CH658247A5 (fr) 1983-03-14 1984-03-13 Analogues de la prostaglandine substitues au 7-oxabicycloheptane.

Country Status (24)

Country Link
KR (1) KR840009085A (enrdf_load_stackoverflow)
AT (1) AT383600B (enrdf_load_stackoverflow)
AU (1) AU567919B2 (enrdf_load_stackoverflow)
CA (1) CA1256887A (enrdf_load_stackoverflow)
CH (1) CH658247A5 (enrdf_load_stackoverflow)
DD (1) DD216932A5 (enrdf_load_stackoverflow)
DE (1) DE3409124A1 (enrdf_load_stackoverflow)
DK (1) DK155584A (enrdf_load_stackoverflow)
ES (1) ES530548A0 (enrdf_load_stackoverflow)
FI (1) FI841008L (enrdf_load_stackoverflow)
FR (1) FR2542743B1 (enrdf_load_stackoverflow)
GB (1) GB2136428B (enrdf_load_stackoverflow)
GR (1) GR79881B (enrdf_load_stackoverflow)
HU (1) HU190530B (enrdf_load_stackoverflow)
IE (1) IE57027B1 (enrdf_load_stackoverflow)
IL (1) IL71184A0 (enrdf_load_stackoverflow)
IT (1) IT1173442B (enrdf_load_stackoverflow)
LU (1) LU85249A1 (enrdf_load_stackoverflow)
NL (1) NL8400797A (enrdf_load_stackoverflow)
NO (1) NO840960L (enrdf_load_stackoverflow)
NZ (1) NZ207361A (enrdf_load_stackoverflow)
PL (1) PL246663A1 (enrdf_load_stackoverflow)
PT (1) PT78242B (enrdf_load_stackoverflow)
SE (1) SE8401398L (enrdf_load_stackoverflow)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513103A (en) * 1983-10-21 1985-04-23 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4560698A (en) * 1984-06-04 1985-12-24 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment in thrombolytic disease
US4661506A (en) * 1984-11-30 1987-04-28 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted ox prostaglandin analogs
US4588743A (en) * 1985-01-22 1986-05-13 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4607049A (en) * 1985-04-22 1986-08-19 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease
US4608386A (en) * 1985-04-26 1986-08-26 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases
US4611006A (en) * 1985-06-28 1986-09-09 E. R. Squibb & Sons, Inc. 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease
US4654356A (en) * 1985-08-01 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs
US4673685A (en) * 1986-07-23 1987-06-16 E. R. Squibb & Sons, Inc. Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
ZA829068B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
JPS58502148A (ja) * 1981-12-23 1983-12-15 ナシヨナル　リサ−チ　デイベロツプメント　コ−ポレイシヨン プロスタグランジン
US4549030A (en) * 1982-12-13 1985-10-22 The Upjohn Company Organic compounds and process
US4526900A (en) * 1984-01-26 1985-07-02 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
US4542157A (en) * 1984-04-27 1985-09-17 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease

Also Published As

Publication number Publication date
FR2542743A1 (fr) 1984-09-21
FI841008A7 (fi) 1984-09-15
GB2136428B (en) 1986-09-10
FI841008L (fi) 1984-09-15
GB8406100D0 (en) 1984-04-11
PT78242A (en) 1984-04-01
IE57027B1 (en) 1992-03-25
GR79881B (enrdf_load_stackoverflow) 1984-10-31
IT8420049A0 (it) 1984-03-14
NL8400797A (nl) 1984-10-01
SE8401398D0 (sv) 1984-03-13
HUT34179A (en) 1985-02-28
DK155584A (da) 1984-09-15
AU567919B2 (en) 1987-12-10
SE8401398L (sv) 1984-09-15
IL71184A0 (en) 1984-06-29
ES8506270A1 (es) 1985-07-01
HU190530B (en) 1986-09-29
GB2136428A (en) 1984-09-19
DE3409124A1 (de) 1984-09-27
ES530548A0 (es) 1985-07-01
KR840009085A (ko) 1984-12-24
IE840525L (en) 1984-09-14
FR2542743B1 (fr) 1987-10-30
AU2523584A (en) 1984-09-20
FI841008A0 (fi) 1984-03-13
PL246663A1 (en) 1985-03-26
NO840960L (no) 1984-09-17
DD216932A5 (de) 1985-01-02
IT1173442B (it) 1987-06-24
CA1256887A (en) 1989-07-04
NZ207361A (en) 1986-12-05
LU85249A1 (fr) 1984-11-14
ATA83484A (de) 1986-12-15
PT78242B (en) 1986-05-27
AT383600B (de) 1987-07-27
DK155584D0 (da) 1984-03-13

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