ES8503001A1 - Un procedimiento para la preparacion de agentes antibacterianos unidos de dicarboxilato de 1,1-alcanodiol - Google Patents

Un procedimiento para la preparacion de agentes antibacterianos unidos de dicarboxilato de 1,1-alcanodiol

Info

Publication number
ES8503001A1
ES8503001A1 ES524894A ES524894A ES8503001A1 ES 8503001 A1 ES8503001 A1 ES 8503001A1 ES 524894 A ES524894 A ES 524894A ES 524894 A ES524894 A ES 524894A ES 8503001 A1 ES8503001 A1 ES 8503001A1
Authority
ES
Spain
Prior art keywords
alkanediol
antibacterial agents
residue
certain
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524894A
Other languages
English (en)
Other versions
ES524894A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES8503001A1 publication Critical patent/ES8503001A1/es
Publication of ES524894A0 publication Critical patent/ES524894A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
    • C07D499/32—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE AGENTES ANTIBACTERIANOS UNIDOS DE DICARBOXILATO DE 1,1-ALCANODIOL.CONSISTE EN HACER REACCIONAR COMPUESTOS DE FORMULA (II) PARA OBTENER AGENTES ANTIBACTERIANOS UNIDOS DE DICARBOXILATO DE 1,1-ALCANODIOL DE FORMULA (I); DONDE A ES ALQUENILO C 1 A 12, ALQUILIDENO C 1 A 12, CICLOALQUILENO C 3 A 7, FENILENO Y OTROS; R ES O O ALQUILO C 1 A 3; N ES 0 O 1; R Y R SON DIFERENTES Y R ES P O B. LA REACCION SE LLEVA A CABO EN PRESENCIA DE UN DISOLVENTE ORGANICO POLAR COMO N,N-DIMETILFORMAMIDA, ACETATO DE ETILO, DICLOROMETANO O CETONA Y A UNA TEMPERATURA ENTRE 25 Y 50JC Y DURANTE 10 MINUTOS A 24 HORAS.TIENE APLICACIONES FARMACEUTICAS POR SU PROPIA NATURALEZA DE AGENTE ANTIBACTERIANO.
ES524894A 1981-12-22 1983-08-11 Un procedimiento para la preparacion de agentes antibacterianos unidos de dicarboxilato de 1,1-alcanodiol Granted ES524894A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33402281A 1981-12-22 1981-12-22
US06/429,915 US4457924A (en) 1981-12-22 1982-09-30 1,1-Alkanediol dicarboxylate linked antibacterial agents

Publications (2)

Publication Number Publication Date
ES8503001A1 true ES8503001A1 (es) 1985-02-01
ES524894A0 ES524894A0 (es) 1985-02-01

Family

ID=26989011

Family Applications (3)

Application Number Title Priority Date Filing Date
ES518425A Expired ES8402310A1 (es) 1981-12-22 1982-12-21 Un procedimiento para la preparacion de agentes antibacterianos unidos de dicarboxilato de 1,1-alcanodiol.
ES524895A Granted ES524895A0 (es) 1981-12-22 1983-08-11 Un procedimiento para la preparacion de agentes antibacterianos unidos de dicarboxilato de 1,1-alcanodiol
ES524894A Granted ES524894A0 (es) 1981-12-22 1983-08-11 Un procedimiento para la preparacion de agentes antibacterianos unidos de dicarboxilato de 1,1-alcanodiol

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES518425A Expired ES8402310A1 (es) 1981-12-22 1982-12-21 Un procedimiento para la preparacion de agentes antibacterianos unidos de dicarboxilato de 1,1-alcanodiol.
ES524895A Granted ES524895A0 (es) 1981-12-22 1983-08-11 Un procedimiento para la preparacion de agentes antibacterianos unidos de dicarboxilato de 1,1-alcanodiol

Country Status (25)

Country Link
US (1) US4457924A (es)
EP (1) EP0083484B1 (es)
JP (1) JPH02270881A (es)
KR (1) KR860001370B1 (es)
AU (1) AU537214B2 (es)
BG (4) BG50161A3 (es)
CA (1) CA1213582A (es)
DD (1) DD207379A5 (es)
DE (1) DE3269267D1 (es)
DK (3) DK565482A (es)
ES (3) ES8402310A1 (es)
FI (1) FI80039C (es)
GR (1) GR77066B (es)
GT (1) GT198200058A (es)
HU (1) HU187737B (es)
IE (1) IE54333B1 (es)
IL (1) IL67530A (es)
NO (1) NO824305L (es)
NZ (1) NZ202670A (es)
PH (1) PH18311A (es)
PL (3) PL141306B1 (es)
PT (1) PT76012B (es)
RO (2) RO87709A (es)
SU (1) SU1405704A3 (es)
YU (2) YU43111B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675186A (en) 1985-04-18 1987-06-23 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
LU87821A1 (fr) * 1990-10-12 1992-05-25 Cird Galderma Composes bi-aromatiques,et leur utilisation en medecine humaine et veterinaire et en cosmetique
ATE115114T1 (de) * 1991-03-11 1994-12-15 Schweizerhall Saeurefab Verfahren zur herstellung von chlorierten carbonsäureestern.
DK0508943T3 (da) * 1991-03-11 1995-01-30 Schweizerhall Saeurefab Fremgangsmåde til fremstilling af halogenerede carboxylsyreestere
AU2003301426A1 (en) * 2002-10-18 2004-05-04 Meiji Seika Kaisha, Ltd. Malonic acid monoesters and process for producing the same
EP2508504B1 (en) * 2009-12-01 2016-04-13 Sumitomo Chemical Co., Ltd Process for preparation of cycloalkanedicarboxylic acid monoesters
US7973194B1 (en) 2010-03-18 2011-07-05 Eastman Chemical Company High solvating cyclohexane dicarboxylate diesters plasticizers
CN115385934A (zh) * 2022-10-26 2022-11-25 北京纳百生物科技有限公司 一种舒巴坦半抗原及其合成方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2985648A (en) * 1958-10-06 1961-05-23 Doyle Frank Peter Alpha-aminobenzylpenicillins
DE1249280B (de) * 1962-11-02 1967-09-07 Beecham GrouD Limited, Brentford Middlesex (Großbritannien) Verfahren zur Herstellung von Hydroxybenzyl y amino-pemciUmen
US3520876A (en) * 1967-11-01 1970-07-21 American Home Prod Process for the preparation of 6-(alpha-aminoacylamino)penicillanic acids
ES436565A1 (es) * 1974-06-05 1977-04-01 Bristol Myers Co Un procedimiento para la preparacion de acidos acetamidope- nicilanicos.
FR2290443A1 (fr) * 1974-11-06 1976-06-04 Aries Robert Nouveaux esters bispenicillaniques
FR2309570A1 (fr) * 1975-04-29 1976-11-26 Aries Robert Derives polymeriques des penicillines et cephalosporines
GB1569421A (en) * 1976-06-11 1980-06-18 Beecham Group Ltd Penicillin compositions
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
IE49881B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4309347A (en) * 1979-05-16 1982-01-05 Pfizer Inc. Penicillanoyloxymethyl penicillanate 1,1,1',1'-tetraoxide

Also Published As

Publication number Publication date
ES8530002A1 (es) 1985-02-01
ES518425A0 (es) 1984-02-01
PL141306B1 (en) 1987-07-31
FI824409L (fi) 1983-06-23
NZ202670A (en) 1985-12-13
GT198200058A (es) 1984-06-09
RO87709B (ro) 1985-10-01
ES8402310A1 (es) 1984-02-01
RO84911A (ro) 1984-08-17
SU1405704A3 (ru) 1988-06-23
NO824305L (no) 1983-06-23
DK69192D0 (da) 1992-05-26
DE3269267D1 (en) 1986-03-27
RO87709A (ro) 1985-10-31
US4457924A (en) 1984-07-03
EP0083484A1 (en) 1983-07-13
YU43992B (en) 1990-02-28
PL248637A1 (en) 1985-02-27
BG48694A3 (en) 1991-04-15
DK69192A (da) 1992-05-26
BG50162A3 (en) 1992-05-15
RO84911B (ro) 1984-09-30
IE54333B1 (en) 1989-08-30
CA1213582A (en) 1986-11-04
AU537214B2 (en) 1984-06-14
BG50161A3 (en) 1992-05-15
PL145927B1 (en) 1988-11-30
PT76012B (en) 1985-12-13
YU43111B (en) 1989-02-28
DK69092A (da) 1992-05-26
EP0083484B1 (en) 1986-02-19
BG50160A3 (en) 1992-05-15
PT76012A (en) 1983-01-01
YU284482A (en) 1985-03-20
FI824409A0 (fi) 1982-12-21
IE823034L (en) 1983-06-22
GR77066B (es) 1984-04-05
ES524894A0 (es) 1985-02-01
YU183084A (en) 1986-10-31
DK69092D0 (da) 1992-05-26
DK565482A (da) 1983-06-23
ES524895A0 (es) 1985-02-01
PL140291B1 (en) 1987-04-30
FI80039C (fi) 1990-04-10
AU9172182A (en) 1983-06-30
DD207379A5 (de) 1984-02-29
HU187737B (en) 1986-02-28
IL67530A0 (en) 1983-05-15
PH18311A (en) 1985-05-29
FI80039B (fi) 1989-12-29
IL67530A (en) 1986-02-28
KR860001370B1 (ko) 1986-09-17
KR840002840A (ko) 1984-07-21
JPH02270881A (ja) 1990-11-05
PL239651A1 (en) 1985-01-16

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