ES8407021A1 - Un procedimiento para la preparacion de derivados de acido 5-oxo-2-pirrolidinpropanoico. - Google Patents

Un procedimiento para la preparacion de derivados de acido 5-oxo-2-pirrolidinpropanoico.

Info

Publication number
ES8407021A1
ES8407021A1 ES522620A ES522620A ES8407021A1 ES 8407021 A1 ES8407021 A1 ES 8407021A1 ES 522620 A ES522620 A ES 522620A ES 522620 A ES522620 A ES 522620A ES 8407021 A1 ES8407021 A1 ES 8407021A1
Authority
ES
Spain
Prior art keywords
oxo
production
acid derivatives
pyrrolidinepropanoic acid
amnesia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES522620A
Other languages
English (en)
Other versions
ES522620A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES522620A0 publication Critical patent/ES522620A0/es
Publication of ES8407021A1 publication Critical patent/ES8407021A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL ACIDO 5-OXO-2-PIRROLIDINOPROPANOICO, DE FORMULA ESTRUCTURAL (I).CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON AL MENOS UNA CANTIDAD MOLAR APROXIMADAMENTE IGUAL DE UN ALCOHOL DE FORMULA: ROH O DE UNA AMINA DE FORMULA: H2NR1R2. SI SE DESEA SE PUEDE CONVERTIR EL ESTER O LA AMIDA RESULTANTE EN UNA SAL DE UN CATION DE METAL O DE AMINA FARMACEUTICAMENTE ACEPTABLE.DE APLICACION EN TERAPEUTICA COMO ACTIVADORES DEL CONOCIMIENTO.
ES522620A 1982-05-24 1983-05-23 Un procedimiento para la preparacion de derivados de acido 5-oxo-2-pirrolidinpropanoico. Expired ES8407021A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38166282A 1982-05-24 1982-05-24
US06/476,524 US4559358A (en) 1982-05-24 1983-03-24 5-Oxo-2-pyrrolidinepropanoic acid and derivatives for reversing electroshock amnesia

Publications (2)

Publication Number Publication Date
ES522620A0 ES522620A0 (es) 1984-09-01
ES8407021A1 true ES8407021A1 (es) 1984-09-01

Family

ID=27009474

Family Applications (1)

Application Number Title Priority Date Filing Date
ES522620A Expired ES8407021A1 (es) 1982-05-24 1983-05-23 Un procedimiento para la preparacion de derivados de acido 5-oxo-2-pirrolidinpropanoico.

Country Status (16)

Country Link
US (1) US4559358A (es)
EP (1) EP0095278B1 (es)
KR (1) KR870000742B1 (es)
AU (1) AU563605B2 (es)
CA (1) CA1240329A (es)
DE (1) DE3378577D1 (es)
DK (1) DK228583A (es)
ES (1) ES8407021A1 (es)
FI (1) FI79097C (es)
GR (1) GR79263B (es)
HU (1) HU189688B (es)
IL (1) IL68520A (es)
NO (1) NO159588C (es)
NZ (1) NZ204320A (es)
PH (1) PH18562A (es)
PT (1) PT76746B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677114A (en) * 1985-11-22 1987-06-30 Warner-Lambert Company Pyrrolidone-2 derivatives and pharmaceutical compositions thereof
DE3718563A1 (de) * 1987-06-03 1988-12-15 Basf Ag Verfahren zur herstellung von substituierten lactamen
AT391692B (de) * 1989-04-24 1990-11-12 Fleischhacker Wilhelm Dr Enantiomerenreine, in position 1 alkylierte 5-oxo-2-pyrrolidinpropansaeuren und deren ester, deren herstellung und verwendung
CA2069912A1 (en) * 1989-10-25 1991-04-26 A. Richard Chamberlin Method of inhibiting the transport of l-glutamate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2496163A (en) * 1948-03-30 1950-01-31 Du Pont Synthesis of a 2-substituted-5-oxopyrrolidine
US2948714A (en) * 1954-02-19 1960-08-09 Roussel Uclaf New n-benzyl peptides and a process of making same
US4372966A (en) * 1980-09-15 1983-02-08 Warner-Lambert Company Use of dihydro-1H-pyrrolizine-3,5(2H,6H)-dione as a cognition activator

Also Published As

Publication number Publication date
ES522620A0 (es) 1984-09-01
CA1240329A (en) 1988-08-09
GR79263B (es) 1984-10-22
FI831794L (fi) 1983-11-25
FI79097C (fi) 1989-11-10
NO159588B (no) 1988-10-10
NO831794L (no) 1983-11-25
AU563605B2 (en) 1987-07-16
US4559358A (en) 1985-12-17
NO159588C (no) 1989-01-18
KR840004721A (ko) 1984-10-24
PT76746A (en) 1983-06-01
FI79097B (fi) 1989-07-31
AU1481583A (en) 1983-12-01
DK228583A (da) 1983-11-25
HU189688B (en) 1986-07-28
EP0095278A3 (en) 1985-05-02
DK228583D0 (da) 1983-05-20
EP0095278A2 (en) 1983-11-30
IL68520A (en) 1986-09-30
PH18562A (en) 1985-08-09
IL68520A0 (en) 1983-07-31
DE3378577D1 (en) 1989-01-05
FI831794A0 (fi) 1983-05-20
NZ204320A (en) 1986-06-11
KR870000742B1 (ko) 1987-04-13
EP0095278B1 (en) 1988-11-30
PT76746B (en) 1985-12-27

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