ATE118773T1 - Verfahren zur herstellung von 2-(3-pyridyl)- tetrahydrothiopyran-2-carbonsäurethioamid-1- (1r,2r)oxyden, die so erhaltenen 2-(3-pyridyl)- tetrahydrothiopyran-2-carbothioamid-1- (1r,2r)oxyde und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents
Verfahren zur herstellung von 2-(3-pyridyl)- tetrahydrothiopyran-2-carbonsäurethioamid-1- (1r,2r)oxyden, die so erhaltenen 2-(3-pyridyl)- tetrahydrothiopyran-2-carbothioamid-1- (1r,2r)oxyde und diese enthaltende pharmazeutische zusammenstellungen.Info
- Publication number
- ATE118773T1 ATE118773T1 AT90403061T AT90403061T ATE118773T1 AT E118773 T1 ATE118773 T1 AT E118773T1 AT 90403061 T AT90403061 T AT 90403061T AT 90403061 T AT90403061 T AT 90403061T AT E118773 T1 ATE118773 T1 AT E118773T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrahydrothiopyran
- pyridyl
- oxides
- carbothiopyran
- pharmaceutical compositions
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- YBQVLKIMKZFEIM-BDJLRTHQSA-N (1r,2r)-1-oxo-2-pyridin-3-ylthiane-2-carbothioamide Chemical class C=1C=CN=CC=1[C@@]1(C(=S)N)CCCC[S@]1=O YBQVLKIMKZFEIM-BDJLRTHQSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- -1 alkyl isothiocyanate Chemical class 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8914273A FR2653770B1 (fr) | 1989-10-31 | 1989-10-31 | Procede de preparation de (pyridyl-3)-2 tetrahydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r), les (pyridyl-3)-2 tetrhydrothiopyrannecarbothioamide-2-oxydes-1-(1r,2r) ainsi obtenus et les compositions pharmaceutiques qui les contiennent. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE118773T1 true ATE118773T1 (de) | 1995-03-15 |
Family
ID=9386963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90403061T ATE118773T1 (de) | 1989-10-31 | 1990-10-30 | Verfahren zur herstellung von 2-(3-pyridyl)- tetrahydrothiopyran-2-carbonsäurethioamid-1- (1r,2r)oxyden, die so erhaltenen 2-(3-pyridyl)- tetrahydrothiopyran-2-carbothioamid-1- (1r,2r)oxyde und diese enthaltende pharmazeutische zusammenstellungen. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5120852A (de) |
| EP (1) | EP0426557B1 (de) |
| JP (1) | JPH03153684A (de) |
| KR (1) | KR910007921A (de) |
| AT (1) | ATE118773T1 (de) |
| AU (1) | AU641950B2 (de) |
| CA (1) | CA2028985A1 (de) |
| DE (1) | DE69017146T2 (de) |
| DK (1) | DK0426557T3 (de) |
| ES (1) | ES2068361T3 (de) |
| FI (1) | FI905358A7 (de) |
| FR (1) | FR2653770B1 (de) |
| GR (1) | GR3015159T3 (de) |
| HU (1) | HU212501B (de) |
| IE (1) | IE66252B1 (de) |
| IL (1) | IL96160A (de) |
| MA (1) | MA21989A1 (de) |
| NO (1) | NO177707C (de) |
| NZ (1) | NZ235872A (de) |
| OA (1) | OA09324A (de) |
| PL (1) | PL164269B1 (de) |
| PT (1) | PT95758A (de) |
| RU (1) | RU1838311C (de) |
| TN (1) | TNSN90128A1 (de) |
| ZA (1) | ZA908679B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9001327D0 (en) * | 1990-01-19 | 1990-03-21 | May & Baker Ltd | New compositions of matter |
| FR2702213B1 (fr) * | 1993-03-02 | 1995-04-07 | Rhone Poulenc Rorer Sa | Procédé de préparation de N-méthyl (pyridyl-3)-2 tétrahydrothiopyrannecarbothioamide-2-oxyde-1-(1R,2R). |
| GB9314133D0 (en) * | 1993-07-08 | 1993-08-18 | Rhone Poulenc Rorer Ltd | New process |
| GB9321939D0 (en) * | 1993-10-25 | 1993-12-15 | Rhone Poulenc Rorer Ltd | New process |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3395142A (en) * | 1963-11-27 | 1968-07-30 | Rohm & Haas | Aminoethylene compositions |
| IE49570B1 (en) * | 1979-03-30 | 1985-10-30 | Rhone Poulenc Ind | 2-(pyrid-2-yl)tetrahydrothiophene derivatives |
| FR2488609A1 (fr) * | 1980-08-18 | 1982-02-19 | Rhone Poulenc Ind | Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent |
| AU543387B2 (en) * | 1981-05-27 | 1985-04-18 | Rhone-Poulenc Sante | Thioformamide derivatives |
| FR2528849B1 (fr) * | 1982-06-17 | 1985-06-21 | Rhone Poulenc Sante | Nouveaux derives de la thioformamide, leur preparation et les medicaments qui les contiennent |
| DE3367631D1 (en) * | 1983-06-16 | 1987-01-02 | Rhone Poulenc Sante | Process for the electrochemical production of sulfoxides of thioformamide derivatives useful as medicines |
-
1989
- 1989-10-31 FR FR8914273A patent/FR2653770B1/fr not_active Expired - Lifetime
-
1990
- 1990-10-26 MA MA22260A patent/MA21989A1/fr unknown
- 1990-10-29 IL IL9616090A patent/IL96160A/en not_active IP Right Cessation
- 1990-10-29 AU AU65548/90A patent/AU641950B2/en not_active Ceased
- 1990-10-29 PL PL90287557A patent/PL164269B1/pl unknown
- 1990-10-29 TN TNTNSN90128A patent/TNSN90128A1/fr unknown
- 1990-10-29 NZ NZ235872A patent/NZ235872A/en unknown
- 1990-10-30 HU HU906945A patent/HU212501B/hu not_active IP Right Cessation
- 1990-10-30 AT AT90403061T patent/ATE118773T1/de not_active IP Right Cessation
- 1990-10-30 CA CA002028985A patent/CA2028985A1/fr not_active Abandoned
- 1990-10-30 FI FI905358A patent/FI905358A7/fi not_active Application Discontinuation
- 1990-10-30 ES ES90403061T patent/ES2068361T3/es not_active Expired - Lifetime
- 1990-10-30 DK DK90403061.6T patent/DK0426557T3/da active
- 1990-10-30 DE DE69017146T patent/DE69017146T2/de not_active Expired - Fee Related
- 1990-10-30 ZA ZA908679A patent/ZA908679B/xx unknown
- 1990-10-30 EP EP90403061A patent/EP0426557B1/de not_active Expired - Lifetime
- 1990-10-30 IE IE390290A patent/IE66252B1/en not_active IP Right Cessation
- 1990-10-30 RU SU904831525A patent/RU1838311C/ru active
- 1990-10-30 NO NO904708A patent/NO177707C/no unknown
- 1990-10-30 KR KR1019900017459A patent/KR910007921A/ko not_active Ceased
- 1990-10-31 US US07/607,003 patent/US5120852A/en not_active Expired - Fee Related
- 1990-10-31 JP JP2292249A patent/JPH03153684A/ja active Pending
- 1990-10-31 PT PT95758A patent/PT95758A/pt unknown
- 1990-10-31 OA OA59883A patent/OA09324A/xx unknown
-
1995
- 1995-02-23 GR GR940402967T patent/GR3015159T3/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |