BG50161A3 - Method for preparing of alcandiol dicarboxilates - Google Patents
Method for preparing of alcandiol dicarboxilatesInfo
- Publication number
- BG50161A3 BG50161A3 BG089818A BG8981882A BG50161A3 BG 50161 A3 BG50161 A3 BG 50161A3 BG 089818 A BG089818 A BG 089818A BG 8981882 A BG8981882 A BG 8981882A BG 50161 A3 BG50161 A3 BG 50161A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- formula
- group
- hydrogen
- bromine
- salt
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- -1 (cn3)2c Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004956 cyclohexylene group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
- 239000003495 polar organic solvent Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
- C07D499/32—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33402281A | 1981-12-22 | 1981-12-22 | |
| US06/429,915 US4457924A (en) | 1981-12-22 | 1982-09-30 | 1,1-Alkanediol dicarboxylate linked antibacterial agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG50161A3 true BG50161A3 (en) | 1992-05-15 |
Family
ID=26989011
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG089818A BG50161A3 (en) | 1981-12-22 | 1982-12-01 | Method for preparing of alcandiol dicarboxilates |
| BG089817A BG50160A3 (en) | 1981-12-22 | 1982-12-01 | Method for preparing of alcandiol dicarboxilates |
| BG089819A BG50162A3 (en) | 1981-12-22 | 1982-12-01 | Method for preparing of alcandiol dicarboxilates |
| BG058979A BG48694A3 (en) | 1981-12-22 | 1982-12-21 | Method for preparing alkandiol- dicarboxilates |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG089817A BG50160A3 (en) | 1981-12-22 | 1982-12-01 | Method for preparing of alcandiol dicarboxilates |
| BG089819A BG50162A3 (en) | 1981-12-22 | 1982-12-01 | Method for preparing of alcandiol dicarboxilates |
| BG058979A BG48694A3 (en) | 1981-12-22 | 1982-12-21 | Method for preparing alkandiol- dicarboxilates |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4457924A (es) |
| EP (1) | EP0083484B1 (es) |
| JP (1) | JPH02270881A (es) |
| KR (1) | KR860001370B1 (es) |
| AU (1) | AU537214B2 (es) |
| BG (4) | BG50161A3 (es) |
| CA (1) | CA1213582A (es) |
| DD (1) | DD207379A5 (es) |
| DE (1) | DE3269267D1 (es) |
| DK (3) | DK565482A (es) |
| ES (3) | ES8402310A1 (es) |
| FI (1) | FI80039C (es) |
| GR (1) | GR77066B (es) |
| GT (1) | GT198200058A (es) |
| HU (1) | HU187737B (es) |
| IE (1) | IE54333B1 (es) |
| IL (1) | IL67530A (es) |
| NO (1) | NO824305L (es) |
| NZ (1) | NZ202670A (es) |
| PH (1) | PH18311A (es) |
| PL (3) | PL141306B1 (es) |
| PT (1) | PT76012B (es) |
| RO (2) | RO87709A (es) |
| SU (1) | SU1405704A3 (es) |
| YU (2) | YU43111B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675186A (en) | 1985-04-18 | 1987-06-23 | Pfizer Inc. | 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives |
| LU87821A1 (fr) * | 1990-10-12 | 1992-05-25 | Cird Galderma | Composes bi-aromatiques,et leur utilisation en medecine humaine et veterinaire et en cosmetique |
| ATE115114T1 (de) * | 1991-03-11 | 1994-12-15 | Schweizerhall Saeurefab | Verfahren zur herstellung von chlorierten carbonsäureestern. |
| DK0508943T3 (da) * | 1991-03-11 | 1995-01-30 | Schweizerhall Saeurefab | Fremgangsmåde til fremstilling af halogenerede carboxylsyreestere |
| AU2003301426A1 (en) * | 2002-10-18 | 2004-05-04 | Meiji Seika Kaisha, Ltd. | Malonic acid monoesters and process for producing the same |
| EP2508504B1 (en) * | 2009-12-01 | 2016-04-13 | Sumitomo Chemical Co., Ltd | Process for preparation of cycloalkanedicarboxylic acid monoesters |
| US7973194B1 (en) | 2010-03-18 | 2011-07-05 | Eastman Chemical Company | High solvating cyclohexane dicarboxylate diesters plasticizers |
| CN115385934A (zh) * | 2022-10-26 | 2022-11-25 | 北京纳百生物科技有限公司 | 一种舒巴坦半抗原及其合成方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2985648A (en) * | 1958-10-06 | 1961-05-23 | Doyle Frank Peter | Alpha-aminobenzylpenicillins |
| DE1249280B (de) * | 1962-11-02 | 1967-09-07 | Beecham GrouD Limited, Brentford Middlesex (Großbritannien) | Verfahren zur Herstellung von Hydroxybenzyl y amino-pemciUmen |
| US3520876A (en) * | 1967-11-01 | 1970-07-21 | American Home Prod | Process for the preparation of 6-(alpha-aminoacylamino)penicillanic acids |
| ES436565A1 (es) * | 1974-06-05 | 1977-04-01 | Bristol Myers Co | Un procedimiento para la preparacion de acidos acetamidope- nicilanicos. |
| FR2290443A1 (fr) * | 1974-11-06 | 1976-06-04 | Aries Robert | Nouveaux esters bispenicillaniques |
| FR2309570A1 (fr) * | 1975-04-29 | 1976-11-26 | Aries Robert | Derives polymeriques des penicillines et cephalosporines |
| GB1569421A (en) * | 1976-06-11 | 1980-06-18 | Beecham Group Ltd | Penicillin compositions |
| US4234579A (en) * | 1977-06-07 | 1980-11-18 | Pfizer Inc. | Penicillanic acid 1,1-dioxides as β-lactamase inhibitors |
| IE49881B1 (en) * | 1979-02-13 | 1986-01-08 | Leo Pharm Prod Ltd | B-lactam intermediates |
| US4244951A (en) * | 1979-05-16 | 1981-01-13 | Pfizer Inc. | Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide |
| US4309347A (en) * | 1979-05-16 | 1982-01-05 | Pfizer Inc. | Penicillanoyloxymethyl penicillanate 1,1,1',1'-tetraoxide |
-
1982
- 1982-09-30 US US06/429,915 patent/US4457924A/en not_active Expired - Lifetime
- 1982-12-01 BG BG089818A patent/BG50161A3/xx unknown
- 1982-12-01 BG BG089817A patent/BG50160A3/xx unknown
- 1982-12-01 NZ NZ202670A patent/NZ202670A/en unknown
- 1982-12-01 BG BG089819A patent/BG50162A3/xx unknown
- 1982-12-14 EP EP82306683A patent/EP0083484B1/en not_active Expired
- 1982-12-14 DE DE8282306683T patent/DE3269267D1/de not_active Expired
- 1982-12-17 GT GT198200058A patent/GT198200058A/es unknown
- 1982-12-20 RO RO82113244A patent/RO87709A/ro unknown
- 1982-12-20 RO RO109396A patent/RO84911B/ro unknown
- 1982-12-21 ES ES518425A patent/ES8402310A1/es not_active Expired
- 1982-12-21 IL IL67530A patent/IL67530A/xx unknown
- 1982-12-21 DD DD82246325A patent/DD207379A5/de not_active IP Right Cessation
- 1982-12-21 AU AU91721/82A patent/AU537214B2/en not_active Ceased
- 1982-12-21 CA CA000418192A patent/CA1213582A/en not_active Expired
- 1982-12-21 PL PL1982239651A patent/PL141306B1/pl unknown
- 1982-12-21 GR GR70128A patent/GR77066B/el unknown
- 1982-12-21 HU HU824105A patent/HU187737B/hu not_active IP Right Cessation
- 1982-12-21 IE IE3034/82A patent/IE54333B1/en not_active IP Right Cessation
- 1982-12-21 NO NO824305A patent/NO824305L/no unknown
- 1982-12-21 BG BG058979A patent/BG48694A3/xx unknown
- 1982-12-21 SU SU823529507A patent/SU1405704A3/ru active
- 1982-12-21 PT PT76012A patent/PT76012B/pt unknown
- 1982-12-21 KR KR8205730A patent/KR860001370B1/ko active
- 1982-12-21 PH PH28306A patent/PH18311A/en unknown
- 1982-12-21 PL PL1982248637A patent/PL140291B1/pl unknown
- 1982-12-21 PL PL1982256903A patent/PL145927B1/pl unknown
- 1982-12-21 YU YU2844/82A patent/YU43111B/xx unknown
- 1982-12-21 FI FI824409A patent/FI80039C/fi not_active IP Right Cessation
- 1982-12-21 DK DK565482A patent/DK565482A/da unknown
-
1983
- 1983-08-11 ES ES524895A patent/ES524895A0/es active Granted
- 1983-08-11 ES ES524894A patent/ES524894A0/es active Granted
-
1984
- 1984-10-25 YU YU1830/84A patent/YU43992B/xx unknown
-
1990
- 1990-02-14 JP JP2033601A patent/JPH02270881A/ja active Pending
-
1992
- 1992-05-26 DK DK069192A patent/DK69192A/da not_active Application Discontinuation
- 1992-05-26 DK DK92690A patent/DK69092D0/da unknown
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