ES8405007A1 - Procedimiento de preparacion de derivados de la quinuclidina - Google Patents
Procedimiento de preparacion de derivados de la quinuclidinaInfo
- Publication number
- ES8405007A1 ES8405007A1 ES524978A ES524978A ES8405007A1 ES 8405007 A1 ES8405007 A1 ES 8405007A1 ES 524978 A ES524978 A ES 524978A ES 524978 A ES524978 A ES 524978A ES 8405007 A1 ES8405007 A1 ES 8405007A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- reacted
- formula
- derivatives substituted
- quinuclidine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- SBYHFKPVCBCYGV-UHFFFAOYSA-N quinuclidine Chemical group C1CC2CCN1CC2 SBYHFKPVCBCYGV-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000011065 in-situ storage Methods 0.000 abstract 2
- LWKDQGSBGMZMNO-UHFFFAOYSA-N 3-methylidene-1-azabicyclo[2.2.2]octane Chemical compound C1CC2C(=C)CN1CC2 LWKDQGSBGMZMNO-UHFFFAOYSA-N 0.000 abstract 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical compound [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012834 electrophilic reactant Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 1
- 150000003624 transition metals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8214215A FR2531955A1 (fr) | 1982-08-17 | 1982-08-17 | Nouveau procede de preparation de derives de la quinuclidine substitues en position 3 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES524978A0 ES524978A0 (es) | 1984-05-16 |
| ES8405007A1 true ES8405007A1 (es) | 1984-05-16 |
Family
ID=9276912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES524978A Expired ES8405007A1 (es) | 1982-08-17 | 1983-08-16 | Procedimiento de preparacion de derivados de la quinuclidina |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4546185A (enExample) |
| EP (1) | EP0102283B1 (enExample) |
| JP (1) | JPS5953484A (enExample) |
| AT (1) | AT389512B (enExample) |
| AU (1) | AU557602B2 (enExample) |
| BR (1) | BR8304411A (enExample) |
| CA (1) | CA1199639A (enExample) |
| DE (1) | DE3368062D1 (enExample) |
| DK (1) | DK161834C (enExample) |
| ES (1) | ES8405007A1 (enExample) |
| FI (1) | FI73212C (enExample) |
| FR (1) | FR2531955A1 (enExample) |
| GR (1) | GR79193B (enExample) |
| HU (1) | HU189731B (enExample) |
| IE (1) | IE55846B1 (enExample) |
| IL (1) | IL69125A0 (enExample) |
| MA (1) | MA19879A1 (enExample) |
| MX (1) | MX159102A (enExample) |
| NO (1) | NO161318C (enExample) |
| PT (1) | PT77197B (enExample) |
| ZA (1) | ZA836022B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3827117A1 (de) * | 1988-08-10 | 1990-02-15 | Ruetgerswerke Ag | Verfahren zur herstellung von chinuclidin-3-methanol |
| US5278170A (en) * | 1989-04-13 | 1994-01-11 | Beecham Group P.L.C. | Azabicylo oxime compounds |
| ES2219636T3 (es) * | 1989-04-13 | 2004-12-01 | Beecham Group P.L.C. | Nuevos compuestos. |
| FI922124A7 (fi) * | 1989-11-17 | 1992-05-11 | Pfizer | Atsabisykloamideja ja estereitä 5-HT3-reseptorin antagonisteina |
| US5446050A (en) * | 1989-11-17 | 1995-08-29 | Pfizer Inc. | Azabicyclo amides and esters as 5-HT3 receptor antagonists |
| WO1994013289A1 (en) * | 1992-12-10 | 1994-06-23 | Tsentr Po Khimii Lekarstvennykh Sredstv | Pharmaceutical compound with anti-ulcer properties |
| EP0747407B1 (en) * | 1995-06-05 | 1999-01-13 | Air Products And Chemicals, Inc. | Hydroxymethyl quinuclidine catalyst compositions for making polyurethane foams |
| US5710191A (en) * | 1995-06-05 | 1998-01-20 | Air Products And Chemicals, Inc. | Hydroxymethyl quinuclidine catalyst compositions for making polyurethane foams |
| FR2777278B1 (fr) * | 1998-04-09 | 2000-06-30 | Pf Medicament | Nouveau procede de preparation de la 3-hydroxymethyl quinuclidine, intermediaire de synthese de la mequitazine |
| CN113929679B (zh) * | 2020-07-14 | 2023-08-11 | 北京博诺安科科技有限公司 | 一种3-氯甲基-1-氮杂双环[2.2.2]辛烷盐酸盐及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1250534A (enExample) * | 1969-03-03 | 1971-10-20 | ||
| FR2052991A1 (en) * | 1969-06-20 | 1971-04-16 | Sogeras | N-(dibenzo (bf) azepines quinuclidines |
| JPS53103426A (en) * | 1977-02-18 | 1978-09-08 | Sato Masao | Method of hydroalumination of olefin |
| JPS6023117B2 (ja) * | 1980-11-10 | 1985-06-05 | 日産化学工業株式会社 | オレフインのハイドロアルミネ−シヨン法 |
-
1982
- 1982-08-17 FR FR8214215A patent/FR2531955A1/fr active Granted
-
1983
- 1983-06-30 IL IL69125A patent/IL69125A0/xx not_active IP Right Cessation
- 1983-07-12 GR GR71916A patent/GR79193B/el unknown
- 1983-08-02 EP EP83401606A patent/EP0102283B1/fr not_active Expired
- 1983-08-02 DE DE8383401606T patent/DE3368062D1/de not_active Expired
- 1983-08-09 CA CA000434200A patent/CA1199639A/fr not_active Expired
- 1983-08-11 US US06/522,288 patent/US4546185A/en not_active Expired - Fee Related
- 1983-08-11 HU HU832826A patent/HU189731B/hu not_active IP Right Cessation
- 1983-08-11 IE IE1890/83A patent/IE55846B1/en not_active IP Right Cessation
- 1983-08-12 PT PT77197A patent/PT77197B/pt not_active IP Right Cessation
- 1983-08-16 DK DK374483A patent/DK161834C/da not_active IP Right Cessation
- 1983-08-16 AT AT0293983A patent/AT389512B/de not_active IP Right Cessation
- 1983-08-16 FI FI832939A patent/FI73212C/fi not_active IP Right Cessation
- 1983-08-16 AU AU18050/83A patent/AU557602B2/en not_active Ceased
- 1983-08-16 ES ES524978A patent/ES8405007A1/es not_active Expired
- 1983-08-16 BR BR8304411A patent/BR8304411A/pt unknown
- 1983-08-16 MA MA20101A patent/MA19879A1/fr unknown
- 1983-08-16 ZA ZA836022A patent/ZA836022B/xx unknown
- 1983-08-16 NO NO832945A patent/NO161318C/no unknown
- 1983-08-16 JP JP58149530A patent/JPS5953484A/ja active Granted
- 1983-08-16 MX MX198399A patent/MX159102A/es unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20040601 |