FR2777278B1 - Nouveau procede de preparation de la 3-hydroxymethyl quinuclidine, intermediaire de synthese de la mequitazine - Google Patents

Nouveau procede de preparation de la 3-hydroxymethyl quinuclidine, intermediaire de synthese de la mequitazine

Info

Publication number
FR2777278B1
FR2777278B1 FR9804451A FR9804451A FR2777278B1 FR 2777278 B1 FR2777278 B1 FR 2777278B1 FR 9804451 A FR9804451 A FR 9804451A FR 9804451 A FR9804451 A FR 9804451A FR 2777278 B1 FR2777278 B1 FR 2777278B1
Authority
FR
France
Prior art keywords
mequitazine
synthesis
preparation
new process
hydroxymethyl quinuclidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9804451A
Other languages
English (en)
Other versions
FR2777278A1 (fr
Inventor
Yves Guminski
Thierry Imbert
Patrick Lesimple
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to FR9804451A priority Critical patent/FR2777278B1/fr
Priority to ES009900709A priority patent/ES2162550B1/es
Priority to ARP990101658A priority patent/AR014977A1/es
Publication of FR2777278A1 publication Critical patent/FR2777278A1/fr
Application granted granted Critical
Publication of FR2777278B1 publication Critical patent/FR2777278B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR9804451A 1998-04-09 1998-04-09 Nouveau procede de preparation de la 3-hydroxymethyl quinuclidine, intermediaire de synthese de la mequitazine Expired - Fee Related FR2777278B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR9804451A FR2777278B1 (fr) 1998-04-09 1998-04-09 Nouveau procede de preparation de la 3-hydroxymethyl quinuclidine, intermediaire de synthese de la mequitazine
ES009900709A ES2162550B1 (es) 1998-04-09 1999-04-08 Procedimiento de preparacion de 3-hidroximetilquinuclidina.
ARP990101658A AR014977A1 (es) 1998-04-09 1999-04-09 Procedimiento de preparacion de la 3-hidroximetilquinuclidina, un compuesto intermediario de sintesis para dicho procedimiento y procedimiento de preparacion de mequitazina

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9804451A FR2777278B1 (fr) 1998-04-09 1998-04-09 Nouveau procede de preparation de la 3-hydroxymethyl quinuclidine, intermediaire de synthese de la mequitazine

Publications (2)

Publication Number Publication Date
FR2777278A1 FR2777278A1 (fr) 1999-10-15
FR2777278B1 true FR2777278B1 (fr) 2000-06-30

Family

ID=9525062

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9804451A Expired - Fee Related FR2777278B1 (fr) 1998-04-09 1998-04-09 Nouveau procede de preparation de la 3-hydroxymethyl quinuclidine, intermediaire de synthese de la mequitazine

Country Status (3)

Country Link
AR (1) AR014977A1 (fr)
ES (1) ES2162550B1 (fr)
FR (1) FR2777278B1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2911606B1 (fr) 2007-01-18 2009-04-17 Pierre Fabre Medicament Sa Nouveau derive de la quinuclidine utile dans la preparation de la mequitazine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2522660A1 (fr) * 1982-03-05 1983-09-09 Pharmuka Lab Isomere levogyre de la mequitazine, son procede de preparation et medicaments le contenant
FR2531955A1 (fr) * 1982-08-17 1984-02-24 Pharmuka Lab Nouveau procede de preparation de derives de la quinuclidine substitues en position 3
DE3827117A1 (de) * 1988-08-10 1990-02-15 Ruetgerswerke Ag Verfahren zur herstellung von chinuclidin-3-methanol
US5137895A (en) * 1991-04-29 1992-08-11 A. H. Robins Company, Incorporated 3-[N-aroyl(or thioaroyl)aminomethyl]-3-quinuclidinols

Also Published As

Publication number Publication date
FR2777278A1 (fr) 1999-10-15
ES2162550A1 (es) 2001-12-16
ES2162550B1 (es) 2003-04-01
AR014977A1 (es) 2001-04-11

Similar Documents

Publication Publication Date Title
EE04915B1 (et) Kinuklidiinderivaadid, nende valmistamismeetod, vahehendid, farmatseutiline kompositsioon ja nende kasutamine
FI20010154A (fi) Menetelmä citalopramin valmistamiseksi
FR2788780B1 (fr) Procede de preparation de vesicules membranaires
FR2866335B1 (fr) Nouveau procede de synthese de l'agomelatine
FR2780728B1 (fr) Sel de paroxetine nouveau, procede pour sa preparation et compositions pharmaceutiques le contenant
MA22539A1 (fr) Procede de preparation de derives de quinuclidine
FR2813077B1 (fr) Procede de preparation du citalopram
FR2645533B1 (fr) Procede de synthese de sulfonylimidures
NO20015017L (no) Fremgangsmate for fremstilling av citalopram
NO20010319D0 (no) Fremgangsmåte for fremstilling av Citalopram
MA25223A1 (fr) Procede pour la preparation de 4-carboxy-amino-2-substitue-1,2,3,4 tetrahydroquinoleine
EE200100328A (et) Antihistamiinsed spiroühendid, vaheühendid ja farmatseutiline kompositsioon ning nende valmistamismeetodid
FR2785609B1 (fr) Procede de preparation de la methionine
FR2741346B1 (fr) Nouveau procede de preparation de derives phenylimidazolidine
ID28601A (id) Proses penyiapan senyawa-senyawa 1,4-dihidropiridin
FR2812632B1 (fr) Procede pour la synthese de composes fluoroorganiques
DZ3489A1 (fr) Procede de preparation de mesylates de derives de piperazine
MA23663A1 (fr) Procede de preparation de formulations pharmaceutiques
FR2777278B1 (fr) Nouveau procede de preparation de la 3-hydroxymethyl quinuclidine, intermediaire de synthese de la mequitazine
FR2776302B1 (fr) Nouveau procede de preparation de la fexofenadine
FR2796641B1 (fr) Nouveau procede de preparation de composes benzoperhydroisoindole
FR2806085B1 (fr) Procede de preparation du citalopram
EE03873B1 (et) Meetod alküüloksüfuranooni amiinderivaatide valmistamiseks, sel meetodil saadud ühendid ja nende kasutamine
FR2805535B1 (fr) Nouveau procede de preparation de l'isoindoline
FR2763942B1 (fr) Nouveau procede de preparation de n-acylaminoacides

Legal Events

Date Code Title Description
ST Notification of lapse