FR2806085B1 - Procede de preparation du citalopram - Google Patents

Procede de preparation du citalopram

Info

Publication number
FR2806085B1
FR2806085B1 FR0103245A FR0103245A FR2806085B1 FR 2806085 B1 FR2806085 B1 FR 2806085B1 FR 0103245 A FR0103245 A FR 0103245A FR 0103245 A FR0103245 A FR 0103245A FR 2806085 B1 FR2806085 B1 FR 2806085B1
Authority
FR
France
Prior art keywords
citalopram
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0103245A
Other languages
English (en)
Other versions
FR2806085A1 (fr
Inventor
Hans Petersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of FR2806085A1 publication Critical patent/FR2806085A1/fr
Application granted granted Critical
Publication of FR2806085B1 publication Critical patent/FR2806085B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
FR0103245A 2000-03-13 2001-03-09 Procede de preparation du citalopram Expired - Fee Related FR2806085B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200000404 2000-03-13

Publications (2)

Publication Number Publication Date
FR2806085A1 FR2806085A1 (fr) 2001-09-14
FR2806085B1 true FR2806085B1 (fr) 2005-02-25

Family

ID=8159323

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0103245A Expired - Fee Related FR2806085B1 (fr) 2000-03-13 2001-03-09 Procede de preparation du citalopram

Country Status (31)

Country Link
US (1) US6717000B2 (fr)
EP (1) EP1265880B1 (fr)
JP (1) JP2003527384A (fr)
KR (1) KR20020080471A (fr)
CN (1) CN1423644A (fr)
AR (1) AR029893A1 (fr)
AT (1) ATE282031T1 (fr)
AU (1) AU3920301A (fr)
BE (1) BE1011598A6 (fr)
BG (1) BG107048A (fr)
BR (1) BR0109267A (fr)
CA (1) CA2402386A1 (fr)
CZ (1) CZ20023383A3 (fr)
DE (1) DE60107061D1 (fr)
EA (1) EA200200971A1 (fr)
FR (1) FR2806085B1 (fr)
HR (1) HRP20020741A2 (fr)
HU (1) HUP0300180A2 (fr)
IE (1) IES20010206A2 (fr)
IL (1) IL151489A0 (fr)
IS (1) IS6528A (fr)
IT (1) ITMI20010487A1 (fr)
MX (1) MXPA02008872A (fr)
NL (1) NL1017500C1 (fr)
NO (1) NO20024214L (fr)
NZ (1) NZ521202A (fr)
PL (1) PL360108A1 (fr)
SK (1) SK14592002A3 (fr)
TR (1) TR200202167T2 (fr)
WO (1) WO2001068628A1 (fr)
ZA (1) ZA200206898B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227473B1 (en) 1999-04-14 2011-07-28 Lundbeck & Co As H Method for preparation of citalopram
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
EA200200969A1 (ru) 2000-03-13 2003-02-27 Х.Лундбекк А/С Способ получения циталопрама
TR200202195T2 (tr) 2000-03-13 2002-12-23 H. Lundbeck A/S 5-Yer değiştirmiş 1-(4-florofenil)-1,3- dihidroizobenzofuran'ın adım adım alkillenmesi
ES2214400T3 (es) 2000-03-14 2004-09-16 H. Lundbeck A/S Metodo para la preparacion de citalopram.
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
WO2004085416A1 (fr) * 2003-03-24 2004-10-07 Hetero Drugs Limited Formes cristallines d'oxalate de (s)-citaloprame
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (fr) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
JP3526581B2 (ja) 1997-07-08 2004-05-17 ハー・ルンドベック・アクティーゼルスカブ シタロプラムの製造方法
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CA2291072C (fr) 1997-11-11 2002-08-20 H. Lundbeck A/S Procede de preparation de citaloprame
DK1123284T3 (da) 1998-10-20 2003-04-28 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
SI1140886T1 (en) 1998-12-23 2003-08-31 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
HU227473B1 (en) 1999-04-14 2011-07-28 Lundbeck & Co As H Method for preparation of citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
SK287139B6 (sk) 1999-10-25 2010-01-07 H. Lundbeck A/S Spôsob prípravy citalopramu
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AU778751B2 (en) 1999-12-28 2004-12-16 H. Lundbeck A/S Method for the preparation of citalopram
EP1246813B1 (fr) 1999-12-30 2003-11-05 H. Lundbeck A/S Procede de preparation de citaloprame
EA005134B1 (ru) 2000-01-14 2004-12-30 Х.Лундбекк А/С Способ получения 5-цианофталида
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
TR200202195T2 (tr) 2000-03-13 2002-12-23 H. Lundbeck A/S 5-Yer değiştirmiş 1-(4-florofenil)-1,3- dihidroizobenzofuran'ın adım adım alkillenmesi
EA200200969A1 (ru) 2000-03-13 2003-02-27 Х.Лундбекк А/С Способ получения циталопрама
GB2357762B (en) 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
ES2214400T3 (es) 2000-03-14 2004-09-16 H. Lundbeck A/S Metodo para la preparacion de citalopram.
JP2003527388A (ja) 2000-03-16 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット ５−シアノ−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフランの製造方法
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
WO2002004435A1 (fr) 2000-07-06 2002-01-17 H. Lundbeck A/S Procede de preparation de citaloprame
CA2354877C (fr) 2000-08-18 2006-05-02 H. Lundbeck A/S Methode de preparation de citalopram
SI1181713T1 (en) 2000-12-22 2005-02-28 H. Lundbeck A/S Method for the preparation of pure citalopram
CA2359810C (fr) 2000-12-28 2002-11-05 H. Lundbeck A/S Procede de preparation de citalopram pur

Also Published As

Publication number Publication date
AU3920301A (en) 2001-09-24
PL360108A1 (en) 2004-09-06
MXPA02008872A (es) 2003-02-10
US20030069304A1 (en) 2003-04-10
KR20020080471A (ko) 2002-10-23
SK14592002A3 (sk) 2003-03-04
TR200202167T2 (tr) 2002-12-23
CA2402386A1 (fr) 2001-09-20
EA200200971A1 (ru) 2003-02-27
ITMI20010487A1 (it) 2002-09-08
DE60107061D1 (de) 2004-12-16
CZ20023383A3 (cs) 2003-01-15
HUP0300180A2 (en) 2003-05-28
EP1265880A1 (fr) 2002-12-18
BG107048A (en) 2003-05-30
BR0109267A (pt) 2002-12-17
NO20024214D0 (no) 2002-09-04
NZ521202A (en) 2004-11-26
ZA200206898B (en) 2004-04-20
CN1423644A (zh) 2003-06-11
IES20010206A2 (en) 2002-03-06
EP1265880B1 (fr) 2004-11-10
BE1011598A6 (fr) 2001-07-03
NL1017500C1 (nl) 2001-04-26
IL151489A0 (en) 2003-04-10
HRP20020741A2 (en) 2003-12-31
WO2001068628A1 (fr) 2001-09-20
FR2806085A1 (fr) 2001-09-14
ATE282031T1 (de) 2004-11-15
JP2003527384A (ja) 2003-09-16
US6717000B2 (en) 2004-04-06
NO20024214L (no) 2002-10-31
IS6528A (is) 2002-08-27
AR029893A1 (es) 2003-07-23

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20051130