BR0109267A - Método para preparação de citalopram; composto e sua composição farmacêutica - Google Patents

Método para preparação de citalopram; composto e sua composição farmacêutica

Info

Publication number
BR0109267A
BR0109267A BR0109267-7A BR0109267A BR0109267A BR 0109267 A BR0109267 A BR 0109267A BR 0109267 A BR0109267 A BR 0109267A BR 0109267 A BR0109267 A BR 0109267A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
citalopram
group
preparing citalopram
Prior art date
Application number
BR0109267-7A
Other languages
English (en)
Inventor
Hans Petersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of BR0109267A publication Critical patent/BR0109267A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"MéTODO PARA PREPARAçãO DE CITALOPRAM; COMPOSTO E SUA COMPOSIçãO FARMACêUTICA". A presente invenção refere-se a um método para a preparação de citalopram compreendendo a redução do composto da fórmula (III), onde X é um grupo ciano ou um grupo o qual pode ser convertido para um grupo ciano, e se X não é um grupo ciano segue-se pela conversão do X para um grupo ciano.
BR0109267-7A 2000-03-13 2001-03-07 Método para preparação de citalopram; composto e sua composição farmacêutica BR0109267A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000404 2000-03-13
PCT/DK2001/000149 WO2001068628A1 (en) 2000-03-13 2001-03-07 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
BR0109267A true BR0109267A (pt) 2002-12-17

Family

ID=8159323

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0109267-7A BR0109267A (pt) 2000-03-13 2001-03-07 Método para preparação de citalopram; composto e sua composição farmacêutica

Country Status (31)

Country Link
US (1) US6717000B2 (pt)
EP (1) EP1265880B1 (pt)
JP (1) JP2003527384A (pt)
KR (1) KR20020080471A (pt)
CN (1) CN1423644A (pt)
AR (1) AR029893A1 (pt)
AT (1) ATE282031T1 (pt)
AU (1) AU3920301A (pt)
BE (1) BE1011598A6 (pt)
BG (1) BG107048A (pt)
BR (1) BR0109267A (pt)
CA (1) CA2402386A1 (pt)
CZ (1) CZ20023383A3 (pt)
DE (1) DE60107061D1 (pt)
EA (1) EA200200971A1 (pt)
FR (1) FR2806085B1 (pt)
HR (1) HRP20020741A2 (pt)
HU (1) HUP0300180A2 (pt)
IE (1) IES20010206A2 (pt)
IL (1) IL151489A0 (pt)
IS (1) IS6528A (pt)
IT (1) ITMI20010487A1 (pt)
MX (1) MXPA02008872A (pt)
NL (1) NL1017500C1 (pt)
NO (1) NO20024214L (pt)
NZ (1) NZ521202A (pt)
PL (1) PL360108A1 (pt)
SK (1) SK14592002A3 (pt)
TR (1) TR200202167T2 (pt)
WO (1) WO2001068628A1 (pt)
ZA (1) ZA200206898B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1142926C (zh) * 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NZ521201A (en) 2000-03-13 2004-02-27 H Method for the preparation of citalopram
EP1265881A1 (en) 2000-03-13 2002-12-18 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (pt) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
DE1015416T1 (de) 1997-07-08 2000-10-05 Lundbeck A S Kobenhavn Valby H Verfahren zur herstellung von citalopram
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
JP3813820B2 (ja) 1997-11-11 2006-08-23 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
EA003057B1 (ru) 1998-12-23 2002-12-26 Х.Лундбекк А/С Способ получения 5-цианофталида
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
CN1142926C (zh) 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
EP1228056B1 (en) 1999-10-25 2004-09-22 H. Lundbeck A/S Method for the preparation of citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
PT1246812E (pt) 1999-12-28 2004-08-31 Lundbeck & Co As H Metodo para a preparacao de citalopram
EP1246813B1 (en) 1999-12-30 2003-11-05 H. Lundbeck A/S Method for the preparation of citalopram
ATE252570T1 (de) 2000-01-14 2003-11-15 Lundbeck & Co As H Verfahren zur herstellung von 5-cyanophthalid
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
NZ521201A (en) 2000-03-13 2004-02-27 H Method for the preparation of citalopram
EP1265881A1 (en) 2000-03-13 2002-12-18 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
GB2357762B (en) 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
EA200200982A1 (ru) 2000-03-16 2003-02-27 Х.Лундбекк А/С Способ получения 5-циано-1-(4-фторфенил)-1,3-дигидроизобензофуранов
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CZ2002832A3 (cs) 2000-07-06 2002-05-15 H. Lundbeck A/S Způsob výroby citalopramu
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
CA2360303C (en) 2000-12-22 2003-08-12 Marco Villa Process for the preparation of pure citalopram
PT1181272E (pt) 2000-12-28 2003-01-31 Lundbeck & Co As H Processo para a preparacao de citalopram puro

Also Published As

Publication number Publication date
CA2402386A1 (en) 2001-09-20
HRP20020741A2 (en) 2003-12-31
DE60107061D1 (de) 2004-12-16
NO20024214D0 (no) 2002-09-04
AU3920301A (en) 2001-09-24
CZ20023383A3 (cs) 2003-01-15
FR2806085B1 (fr) 2005-02-25
SK14592002A3 (sk) 2003-03-04
PL360108A1 (en) 2004-09-06
ITMI20010487A1 (it) 2002-09-08
CN1423644A (zh) 2003-06-11
IS6528A (is) 2002-08-27
JP2003527384A (ja) 2003-09-16
US20030069304A1 (en) 2003-04-10
AR029893A1 (es) 2003-07-23
EA200200971A1 (ru) 2003-02-27
US6717000B2 (en) 2004-04-06
TR200202167T2 (tr) 2002-12-23
ATE282031T1 (de) 2004-11-15
IES20010206A2 (en) 2002-03-06
NZ521202A (en) 2004-11-26
KR20020080471A (ko) 2002-10-23
ZA200206898B (en) 2004-04-20
IL151489A0 (en) 2003-04-10
BG107048A (en) 2003-05-30
FR2806085A1 (fr) 2001-09-14
EP1265880A1 (en) 2002-12-18
WO2001068628A1 (en) 2001-09-20
MXPA02008872A (es) 2003-02-10
HUP0300180A2 (en) 2003-05-28
NL1017500C1 (nl) 2001-04-26
NO20024214L (no) 2002-10-31
BE1011598A6 (fr) 2001-07-03
EP1265880B1 (en) 2004-11-10

Similar Documents

Publication Publication Date Title
BR9714925A (pt) Método para preparação de citalopran, composto e composição farmacêutica antidepressiva
BR9714924A (pt) Método para preparação de citalopram, composto, e sua composição farmacêutica
BR0108947A (pt) Método para preparação e citalopram; intermediário e sua composição farmacêutica
CA2431068A1 (en) Crystalline forms of atorvastatin
BR0212185A (pt) Compostos e métodos para a preparação de compostos
WO1998019513A3 (en) Method for the preparation of citalopram
BR0012434A (pt) Composto, processo para a preparação do mesmo, uso de um composto, composição farmacêutica.
BR0113162A (pt) Ariloxialquilaminas nao-imidazóis
GR20010100398A (el) Μεθοδος παρασκευης της σιταλοπραμης.
BR0109267A (pt) Método para preparação de citalopram; composto e sua composição farmacêutica
BR0212353A (pt) Composto, composição farmacêutica, e, uso de um composto
EA200000431A3 (ru) Новые замещенные димерные соединения, способ их получения и фармацевтические композиции, содержащие их
BR0109022A (pt) Método de preparação de citalopram e sua composição farmacêutica
HUP0300856A2 (hu) Eljárás szubsztituált fenil-acetonitrilek elżállítására
BR0110996A (pt) Método para preparação de citalopram; composto; intermediário e, sua composição farmacêutica
EA200200728A1 (ru) Способ получения циталопрама
BR0109268A (pt) Método de preparação de citalopram, composto e citaplopram
BR0109176A (pt) Método para preparação de citalopram e composto da fórmula
BR9912870A (pt) Processo para sìntese de derivados de (1h) - benzo (c)quinolizina-3-onas
TR200400293T4 (tr) 9-dihidro-13-asetilbasatin III'e ait suda çözünebilir 9-dihidro-paklitaksel türevlerinin sentezi.
DK0683165T3 (da) Fremgangsmåde til fremstilling af N-alkyl-N-pyridinyl-1H-indol-1-aminer
PT1282617E (pt) Derivados de hidantoína com afinidade para os receptores da somatostatina
BR0114258A (pt) Esteróides de 17alfa-fluoroalquila, processo para sua produção e composições farmacêuticas que contêm estes compostos
ID27440A (id) Proses untuk menyiapkan penengah-penengah
BR0012599A (pt) Método para preparação de debromohimenialdisina e análogos desta

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008.