ES8705860A1 - Procedimiento de preparacion de derivados de 3-hidroxi-3-fenilpiperidina - Google Patents

Procedimiento de preparacion de derivados de 3-hidroxi-3-fenilpiperidina

Info

Publication number
ES8705860A1
ES8705860A1 ES551777A ES551777A ES8705860A1 ES 8705860 A1 ES8705860 A1 ES 8705860A1 ES 551777 A ES551777 A ES 551777A ES 551777 A ES551777 A ES 551777A ES 8705860 A1 ES8705860 A1 ES 8705860A1
Authority
ES
Spain
Prior art keywords
hydroxy
phenylpiperidine
ethyl
preparation
therapeutical use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551777A
Other languages
English (en)
Other versions
ES551777A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8501410A external-priority patent/FR2576898B1/fr
Priority claimed from FR8510550A external-priority patent/FR2584714B1/fr
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Publication of ES551777A0 publication Critical patent/ES551777A0/es
Publication of ES8705860A1 publication Critical patent/ES8705860A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

METODO DE PREPARAR DERIVADOS DE 3-HIDROXI-3-FENIL-PIPERIDINA. CONSISTE EN HACER REACCIONAR UN HALOGENURO DE FENILMAGNESIO DE FORMULA C6H5MGX CON UNA 3-PIPERIDINA DE FORMULA (IV), DURANTE 0,25 H A TEMPERATURA ENTRE 0 Y 25JC, BAJO ATMOSFERA DE NITROGENO, EN UN SOLVENTE INERTE TAL COMO DIETILETER, PARA OBTENER DERIVADOS DE 3-HIDROXI-3-FENILPIPERIDINA Y SUS SALES DE ADICION DE FORMULAS (I), (II) O (III), DONDE R ES UN GRUPO ALQUILO DE C 2 A 4. TIENEN APLICACION PARA PREPARAR COMPOSICIONES FARMACEUTICAS.
ES551777A 1985-02-01 1986-01-30 Procedimiento de preparacion de derivados de 3-hidroxi-3-fenilpiperidina Expired ES8705860A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8501410A FR2576898B1 (fr) 1985-02-01 1985-02-01 Derives de 3-phenyl-tetrahydropyridine, procede de preparation et utilisation en therapeutique
FR8510550A FR2584714B1 (fr) 1985-07-10 1985-07-10 Derives de 3-hydroxy-3-phenylpiperidine, procede de preparation et utilisation en therapeutique

Publications (2)

Publication Number Publication Date
ES551777A0 ES551777A0 (es) 1987-05-16
ES8705860A1 true ES8705860A1 (es) 1987-05-16

Family

ID=26224357

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551777A Expired ES8705860A1 (es) 1985-02-01 1986-01-30 Procedimiento de preparacion de derivados de 3-hidroxi-3-fenilpiperidina

Country Status (10)

Country Link
US (1) US4680302A (es)
EP (1) EP0192522B1 (es)
JP (1) JPH0649684B2 (es)
CA (1) CA1263659A (es)
DE (1) DE3660628D1 (es)
DK (1) DK49986A (es)
ES (1) ES8705860A1 (es)
GR (1) GR860323B (es)
IE (1) IE58931B1 (es)
PT (1) PT81950B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703354B1 (fr) * 1993-03-31 1995-06-30 Lafon Labor Derives de 1, 2, 5, 6-tetrahydropyridine, leur procede de preparation et leurs applications en therapeutique.
FR2721514B1 (fr) * 1994-06-23 1996-09-06 Lafon Labor Compositions thérapeutiques comprenant des 3-phényl-3-hydroxypipéridines.
US7240408B2 (en) * 2004-01-14 2007-07-10 Icon Textile Laser Systems, Inc. Selectivity altering a fiber height in a pile fabric and apparatus

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA672114A (en) * 1963-10-15 H. Beckett Arnold Analgesic compositions
US2589943A (en) * 1941-10-01 1952-03-18 Ferrosan As 4-aryl-4-acyl-oxy-piperidines
GB576962A (en) * 1944-05-05 1946-04-29 Geoffrey Malcolm Badger New piperidine derivatives
GB1049564A (en) * 1964-02-12 1966-11-30 Allen & Hanburys Ltd Piperidine derivatives
FR1455825A (fr) * 1965-02-18 1966-05-20 Degussa Procédé de préparation de phényl-tétrahydropyridines substituées
US4263438A (en) * 1977-09-13 1981-04-21 Pfizer Inc. 3-[2,4-(Disubstituted)-phenyl]azacycloalkanones as analgesics
FR2496099A1 (fr) * 1980-12-15 1982-06-18 Roussel Uclaf Nouveaux derives de l'hydroxyphenyl tetrahydropyridine, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant

Also Published As

Publication number Publication date
CA1263659A (fr) 1989-12-05
DK49986D0 (da) 1986-01-31
ES551777A0 (es) 1987-05-16
DE3660628D1 (en) 1988-10-06
IE860245L (en) 1986-08-01
EP0192522A1 (fr) 1986-08-27
PT81950A (fr) 1986-02-01
GR860323B (en) 1986-06-04
US4680302A (en) 1987-07-14
IE58931B1 (en) 1993-12-01
JPS61183266A (ja) 1986-08-15
DK49986A (da) 1986-08-02
JPH0649684B2 (ja) 1994-06-29
PT81950B (pt) 1987-12-30
EP0192522B1 (fr) 1988-08-31

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