ES8703840A1 - Un procedimiento para preparar un derivado de piridinilmeti-cetona - Google Patents

Un procedimiento para preparar un derivado de piridinilmeti-cetona

Info

Publication number
ES8703840A1
ES8703840A1 ES550525A ES550525A ES8703840A1 ES 8703840 A1 ES8703840 A1 ES 8703840A1 ES 550525 A ES550525 A ES 550525A ES 550525 A ES550525 A ES 550525A ES 8703840 A1 ES8703840 A1 ES 8703840A1
Authority
ES
Spain
Prior art keywords
benzoyl
lower alkanoyl
dihydropyridines
methylidene
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550525A
Other languages
English (en)
Other versions
ES550525A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Torcan Chemical Ltd
Original Assignee
Torcan Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torcan Chemical Ltd filed Critical Torcan Chemical Ltd
Publication of ES8703840A1 publication Critical patent/ES8703840A1/es
Publication of ES550525A0 publication Critical patent/ES550525A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE PIRIDINILMETIL-CETONA, DE FORMULA (I). COMPRENDE LA REACCION DE UN COMPUESTO DE FORMULA (II), O UNA DE SUS SALES DE ADICION DE ACIDO, CON AGUA O CON UN ALCANOL INFERIOR PARA OBTENER EL COMPUESTO DE FORMULA (I), EN LAS QUE R Y R1 REPRESENTAN ALQUILO C1-5, ARILO O ARALQUILO. LA REACCION SE LLEVA A CABO A LA TEMPERATURA DE REFLUJO DE LA MEZCLA. ESTOS COMPUESTOS TIENEN APLICACIONES COMO INTERMEDIOS EN LA SINTESIS DE COMPUESTOS CON ACTIVIDAD CARDIOTONICA.
ES550525A 1985-06-11 1985-12-30 Un procedimiento para preparar un derivado de piridinilmeti-cetona Expired ES8703840A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/743,499 US4681944A (en) 1985-06-11 1985-06-11 Process for preparing certain 1-lower alkanoyl or benzoyl-4-(lower alkanoyl or benzoyl-methylidene)-1,4-dihydropyridines or acid addition salts thereof

Publications (2)

Publication Number Publication Date
ES8703840A1 true ES8703840A1 (es) 1987-03-01
ES550525A0 ES550525A0 (es) 1987-03-01

Family

ID=24989011

Family Applications (1)

Application Number Title Priority Date Filing Date
ES550525A Expired ES8703840A1 (es) 1985-06-11 1985-12-30 Un procedimiento para preparar un derivado de piridinilmeti-cetona

Country Status (2)

Country Link
US (1) US4681944A (es)
ES (1) ES8703840A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5493024A (en) * 1991-04-11 1996-02-20 Dowelanco 3,4,N-trisubstituted-4,5-dihydro-1H-pyrazole-1-carboxamides and their use as insectioides
US6118002A (en) * 1999-03-02 2000-09-12 Wyckoff Chemical Company, Inc. Purification of 1,2-dihydro-6-alkyl-2-oxo-5-(pyridinyl)-nicotinonitriles
CN103848779A (zh) * 2013-11-01 2014-06-11 济南大学 一种1-( 4-吡啶基) 丙酮的制备方法
CN106631999B (zh) * 2016-11-30 2019-12-03 湖州恒远生物化学技术有限公司 一种1-(4-吡啶基)-2-丙酮的制备方法
CN113493410B (zh) * 2020-03-20 2024-05-14 鲁南制药集团股份有限公司 一种米力农的制备工艺
CN113493412B (zh) * 2020-03-20 2024-06-14 鲁南制药集团股份有限公司 一种制备米力农的新工艺
CN113493405A (zh) * 2020-03-20 2021-10-12 鲁南制药集团股份有限公司 一种4-(二甲胺基)-3-(吡啶-4-基)丁-3-烯-2-酮的制备方法
CN113493406B (zh) * 2020-03-20 2024-06-14 鲁南制药集团股份有限公司 一种米力农中间体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347363A (en) * 1981-09-17 1982-08-31 Sterling Drug Inc. Process for preparing 1,2-dihydro-6-methyl-2-oxo-5-(pyridinyl)nicotinonitriles
US4417054A (en) * 1982-05-24 1983-11-22 Sterling Drug Inc. 2-(Lower-alkoxy)-1-(pyridinyl)ethenyl lower-alkyl ketones
US4469871A (en) * 1982-05-24 1984-09-04 Sterling Drug Inc. Process for preparing 2-(lower-alkoxy)-1-(pyridinyl) ethenyl lower-alkyl ketones
US4413127A (en) * 1982-05-24 1983-11-01 Sterling Drug Inc. Preparation of 1,2-dihydro-6-(lower alkyl)-2-oxo-5-(pyridinyl)nicotinonitriles

Also Published As

Publication number Publication date
US4681944A (en) 1987-07-21
ES550525A0 (es) 1987-03-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603