ES8301965A1 - Procedimiento para preparar derivados de acido quinolina- carboxilico - Google Patents
Procedimiento para preparar derivados de acido quinolina- carboxilicoInfo
- Publication number
- ES8301965A1 ES8301965A1 ES505207A ES505207A ES8301965A1 ES 8301965 A1 ES8301965 A1 ES 8301965A1 ES 505207 A ES505207 A ES 505207A ES 505207 A ES505207 A ES 505207A ES 8301965 A1 ES8301965 A1 ES 8301965A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- carboxylic acid
- acid derivatives
- quinoline carboxylic
- piperazinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ACIDO QUINOLINA- CARBOXILICO, DE FORMULA (I), EN LA QUE R ES ETILO O VINILO; Y R ES UN GRUPO DE FORMULA (II) EN LA QUE R ES HIDROGENO O ALQUILO INFERIOR. CONSISTE EN LA REACCION DE HIDROLISIS DE UN COMPUESTO DE FORMULA (III), EN LA QUE R ES ALQUILO INFERIOR Y R Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN MEDIO ACIDO, CON ACIDO CLORHIDRICO, CALENTADO A LA TEMPERATURA DE REFLUJO, O EN MEDIO ALCALINO, CON HIDROXIDO SODICO, CALENTADO A UNA TEMPERATURA ENTRE 50<025>C Y 100<025>C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIMICROBIALES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55123024A JPS5762259A (en) | 1980-09-05 | 1980-09-05 | Preparation of substituted quinolinecarboxylic acid derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8301965A1 true ES8301965A1 (es) | 1982-12-16 |
ES505207A0 ES505207A0 (es) | 1982-12-16 |
Family
ID=14850324
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES505207A Granted ES505207A0 (es) | 1980-09-05 | 1981-09-04 | Procedimiento para preparar derivados de acido quinolina- carboxilico |
ES514699A Expired ES8305752A1 (es) | 1980-09-05 | 1982-08-03 | Procedimiento para preparar esteres de acidos quinolina-car boxilicos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES514699A Expired ES8305752A1 (es) | 1980-09-05 | 1982-08-03 | Procedimiento para preparar esteres de acidos quinolina-car boxilicos. |
Country Status (29)
Country | Link |
---|---|
US (1) | US4472579A (es) |
JP (1) | JPS5762259A (es) |
KR (1) | KR870001944B1 (es) |
AR (1) | AR226917A1 (es) |
AT (1) | AT380009B (es) |
AU (1) | AU540205B2 (es) |
BE (1) | BE890223A (es) |
CA (1) | CA1214466A (es) |
CH (1) | CH646697A5 (es) |
DE (1) | DE3135125A1 (es) |
DK (1) | DK154763C (es) |
ES (2) | ES505207A0 (es) |
FI (1) | FI77854C (es) |
FR (1) | FR2489821B1 (es) |
GB (1) | GB2085875B (es) |
GR (1) | GR74304B (es) |
HU (1) | HU187356B (es) |
IE (1) | IE51540B1 (es) |
IN (1) | IN155106B (es) |
IT (1) | IT1168168B (es) |
LU (1) | LU83609A1 (es) |
MX (1) | MX7101E (es) |
NL (1) | NL193375C (es) |
NO (1) | NO157699C (es) |
NZ (1) | NZ198295A (es) |
PH (1) | PH17837A (es) |
PT (1) | PT73571B (es) |
SE (1) | SE442402B (es) |
ZA (1) | ZA815207B (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4670444B1 (en) * | 1980-09-03 | 1999-02-09 | Bayer Ag | and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds |
DE3142854A1 (de) * | 1981-10-29 | 1983-05-11 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
JPS59122470A (ja) * | 1982-12-27 | 1984-07-14 | Dai Ichi Seiyaku Co Ltd | キノリン−3−カルボン酸誘導体の製造法 |
DE3306771A1 (de) * | 1983-02-25 | 1984-08-30 | Bayer Ag, 5090 Leverkusen | Chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
DE3318145A1 (de) * | 1983-05-18 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
AU553415B2 (en) * | 1983-09-19 | 1986-07-17 | Abbott Japan Co., Ltd. | 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids |
DE3504643A1 (de) * | 1985-02-12 | 1986-08-14 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-1,4-dihydro-4-oxo-7-(4-(2-oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl)-3-chinolin carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
HUT40429A (en) * | 1985-04-29 | 1986-12-28 | Chinoin Gyogyszer Es Vegyeszet | Process for production of salts of derivatives of kynolin carbonic acid |
DE3525108A1 (de) * | 1985-06-07 | 1986-12-11 | Bayer Ag, 5090 Leverkusen | Antibakteriell wirksame chinoloncarbonsaeureester |
DE3525335A1 (de) * | 1985-07-16 | 1987-01-22 | Bayer Ag | Embonate von chinoloncarbonsaeuren und ihren derivaten |
DE3542002A1 (de) * | 1985-11-28 | 1987-06-04 | Bayer Ag | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
HU196218B (en) | 1985-12-09 | 1988-10-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing quinoline carboxylic acid boric acid anhydrides |
CA1306750C (en) | 1985-12-09 | 1992-08-25 | Istvan Hermecz | Process for the preparation of quinoline carboxylic acide |
SI8712447A8 (en) * | 1987-12-31 | 1995-12-31 | Krka Tovarna Zdravil | Process for preparing 1-substituted 6-fluoro-4-oxo-7-(1-piperazinyl) -1,4-dihydroquinoline-3-carboxylic acid and new intermediate used in this process |
SI9200377A (en) | 1992-12-11 | 1994-06-30 | Krka | Process for the preparation of 1-substituted 6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxilic acid, novel intermediate used in this process and process for its preparation |
US6584615B1 (en) * | 1998-11-06 | 2003-07-01 | Mission Hockey Company | Asymmetrical hockey glove system with articulated locking thumb |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2504875A (en) * | 1945-06-04 | 1950-04-18 | Us Sec War | Method for producing 4-hydroxyquinolines |
US4017622A (en) * | 1972-12-18 | 1977-04-12 | Dainippon Pharmaceutical Co., Ltd. | Piperazine derivatives |
JPS5732059B2 (es) * | 1974-02-09 | 1982-07-08 | ||
FI311974A (es) * | 1973-10-26 | 1975-04-27 | Dainippon Pharmaceutical Co | |
JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
CA1175836A (en) * | 1977-09-20 | 1984-10-09 | Marcel Pesson | Production of 1,4-dihydroquinoline-3-carboxylic acid derivatives |
JPS5466686A (en) * | 1977-09-20 | 1979-05-29 | Dainippon Pharmaceut Co Ltd | Quinoline-3-carboxylic acid derivative, its preparation, and pharmaceutical composition containig the same |
JPS54141286A (en) * | 1978-04-14 | 1979-11-02 | Matsuo Kogyo | Spool detachable system in spinning reel for fishing |
JPS54138582A (en) * | 1978-04-19 | 1979-10-27 | Kyorin Seiyaku Kk | Substituted quinolinecarboxylic acid |
JPS5540656A (en) * | 1978-09-19 | 1980-03-22 | Kyorin Pharmaceut Co Ltd | Substituted quinoline-carboxylic acid derivative |
JPS5845426B2 (ja) * | 1978-09-29 | 1983-10-08 | 杏林製薬株式会社 | 置換キノリンカルボン酸誘導体 |
-
1980
- 1980-09-05 JP JP55123024A patent/JPS5762259A/ja active Granted
-
1981
- 1981-07-22 GR GR65585A patent/GR74304B/el unknown
- 1981-07-29 ZA ZA815207A patent/ZA815207B/xx unknown
- 1981-07-29 CH CH490981A patent/CH646697A5/de not_active IP Right Cessation
- 1981-07-30 IN IN855/CAL/81A patent/IN155106B/en unknown
- 1981-08-04 NL NL8103679A patent/NL193375C/nl not_active IP Right Cessation
- 1981-08-07 NO NO812686A patent/NO157699C/no unknown
- 1981-08-17 FI FI812538A patent/FI77854C/fi not_active IP Right Cessation
- 1981-08-17 AT AT0358881A patent/AT380009B/de not_active IP Right Cessation
- 1981-08-25 AU AU74611/81A patent/AU540205B2/en not_active Expired
- 1981-08-26 PT PT73571A patent/PT73571B/pt unknown
- 1981-08-27 DK DK380681A patent/DK154763C/da not_active IP Right Cessation
- 1981-08-28 SE SE8105102A patent/SE442402B/sv not_active IP Right Cessation
- 1981-08-31 US US06/298,333 patent/US4472579A/en not_active Expired - Lifetime
- 1981-09-01 GB GB8126513A patent/GB2085875B/en not_active Expired
- 1981-09-02 AR AR286620A patent/AR226917A1/es active
- 1981-09-02 IE IE2028/81A patent/IE51540B1/en not_active IP Right Cessation
- 1981-09-02 MX MX819646A patent/MX7101E/es unknown
- 1981-09-03 HU HU812549A patent/HU187356B/hu unknown
- 1981-09-04 DE DE19813135125 patent/DE3135125A1/de active Granted
- 1981-09-04 FR FR8116886A patent/FR2489821B1/fr not_active Expired
- 1981-09-04 IT IT23799/81A patent/IT1168168B/it active Protection Beyond IP Right Term
- 1981-09-04 BE BE2/59340A patent/BE890223A/fr not_active IP Right Cessation
- 1981-09-04 CA CA000385201A patent/CA1214466A/en not_active Expired
- 1981-09-04 ES ES505207A patent/ES505207A0/es active Granted
- 1981-09-05 KR KR1019810003314A patent/KR870001944B1/ko active
- 1981-09-07 LU LU83609A patent/LU83609A1/fr unknown
- 1981-09-07 NZ NZ198295A patent/NZ198295A/en unknown
- 1981-09-07 PH PH26158A patent/PH17837A/en unknown
-
1982
- 1982-08-03 ES ES514699A patent/ES8305752A1/es not_active Expired
Also Published As
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