KR830007562A - 퀴놀린 카르복실산 유도체의 제조방법 - Google Patents

퀴놀린 카르복실산 유도체의 제조방법 Download PDF

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Publication number
KR830007562A
KR830007562A KR1019810003314A KR810003314A KR830007562A KR 830007562 A KR830007562 A KR 830007562A KR 1019810003314 A KR1019810003314 A KR 1019810003314A KR 810003314 A KR810003314 A KR 810003314A KR 830007562 A KR830007562 A KR 830007562A
Authority
KR
South Korea
Prior art keywords
carboxylic acid
acid derivative
quinoline carboxylic
substituted
preparing quinoline
Prior art date
Application number
KR1019810003314A
Other languages
English (en)
Other versions
KR870001944B1 (ko
Inventor
쓰도무 이리구라
토시애 시바
히로시 마쓰구보
Original Assignee
하기하라 히데시
쿄린 세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14850324&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR830007562(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 하기하라 히데시, 쿄린 세이야꾸 가부시끼가이샤 filed Critical 하기하라 히데시
Publication of KR830007562A publication Critical patent/KR830007562A/ko
Application granted granted Critical
Publication of KR870001944B1 publication Critical patent/KR870001944B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Abstract

내용 없음

Description

퀴놀린 카르복실산 유도체의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 하기구조식(I)의 1-치환-6-플루오로-7-클로로-4-옥소-1,4-디히드로퀴놀린-3-카르복실산에스테르유도체와 하기 구조식(II)의 피페라진 유도체를 반응시켜서 산출한 구조식(Ⅲ)의 화합물을 수화하는단계로 구성되는 구조식(IV)의 1-치환-6-플루오로-7-(1-피레라지닐 혹은 4-치환된-1-피레라지닐)-4-옥소-1,4-디히드로퀴놀린-3-카르복실산의 제조방법:
    상기 식중에서, R1은 에틸 혹는 비닐기이고, R2는 저급알킬이고,
    R3는 수소원자 혹은 저급알킬기이고, R4는임.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019810003314A 1980-09-05 1981-09-05 퀴놀린 카르복실산 유도체의 제조방법 KR870001944B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55123024A JPS5762259A (en) 1980-09-05 1980-09-05 Preparation of substituted quinolinecarboxylic acid derivative
JP80-123024 1980-09-05

Publications (2)

Publication Number Publication Date
KR830007562A true KR830007562A (ko) 1983-10-21
KR870001944B1 KR870001944B1 (ko) 1987-10-23

Family

ID=14850324

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810003314A KR870001944B1 (ko) 1980-09-05 1981-09-05 퀴놀린 카르복실산 유도체의 제조방법

Country Status (29)

Country Link
US (1) US4472579A (ko)
JP (1) JPS5762259A (ko)
KR (1) KR870001944B1 (ko)
AR (1) AR226917A1 (ko)
AT (1) AT380009B (ko)
AU (1) AU540205B2 (ko)
BE (1) BE890223A (ko)
CA (1) CA1214466A (ko)
CH (1) CH646697A5 (ko)
DE (1) DE3135125A1 (ko)
DK (1) DK154763C (ko)
ES (2) ES8301965A1 (ko)
FI (1) FI77854C (ko)
FR (1) FR2489821B1 (ko)
GB (1) GB2085875B (ko)
GR (1) GR74304B (ko)
HU (1) HU187356B (ko)
IE (1) IE51540B1 (ko)
IN (1) IN155106B (ko)
IT (1) IT1168168B (ko)
LU (1) LU83609A1 (ko)
MX (1) MX7101E (ko)
NL (1) NL193375C (ko)
NO (1) NO157699C (ko)
NZ (1) NZ198295A (ko)
PH (1) PH17837A (ko)
PT (1) PT73571B (ko)
SE (1) SE442402B (ko)
ZA (1) ZA815207B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4670444B1 (en) * 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
JPS59122470A (ja) * 1982-12-27 1984-07-14 Dai Ichi Seiyaku Co Ltd キノリン−３−カルボン酸誘導体の製造法
DE3306771A1 (de) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen Chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
DE3504643A1 (de) * 1985-02-12 1986-08-14 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-1,4-dihydro-4-oxo-7-(4-(2-oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl)-3-chinolin carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
HUT40429A (en) * 1985-04-29 1986-12-28 Chinoin Gyogyszer Es Vegyeszet Process for production of salts of derivatives of kynolin carbonic acid
DE3525108A1 (de) * 1985-06-07 1986-12-11 Bayer Ag, 5090 Leverkusen Antibakteriell wirksame chinoloncarbonsaeureester
DE3525335A1 (de) * 1985-07-16 1987-01-22 Bayer Ag Embonate von chinoloncarbonsaeuren und ihren derivaten
DE3542002A1 (de) * 1985-11-28 1987-06-04 Bayer Ag 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
CA1306750C (en) 1985-12-09 1992-08-25 Istvan Hermecz Process for the preparation of quinoline carboxylic acide
HU196218B (en) 1985-12-09 1988-10-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing quinoline carboxylic acid boric acid anhydrides
SI8712447A8 (en) 1987-12-31 1995-12-31 Krka Tovarna Zdravil Process for preparing 1-substituted 6-fluoro-4-oxo-7-(1-piperazinyl) -1,4-dihydroquinoline-3-carboxylic acid and new intermediate used in this process
SI9200377A (en) 1992-12-11 1994-06-30 Krka Process for the preparation of 1-substituted 6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxilic acid, novel intermediate used in this process and process for its preparation
US6584615B1 (en) * 1998-11-06 2003-07-01 Mission Hockey Company Asymmetrical hockey glove system with articulated locking thumb

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2504875A (en) * 1945-06-04 1950-04-18 Us Sec War Method for producing 4-hydroxyquinolines
US4017622A (en) * 1972-12-18 1977-04-12 Dainippon Pharmaceutical Co., Ltd. Piperazine derivatives
JPS5732059B2 (ko) * 1974-02-09 1982-07-08
FI311974A (ko) * 1973-10-26 1975-04-27 Dainippon Pharmaceutical Co
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
CA1175836A (en) * 1977-09-20 1984-10-09 Marcel Pesson Production of 1,4-dihydroquinoline-3-carboxylic acid derivatives
JPS5466686A (en) * 1977-09-20 1979-05-29 Dainippon Pharmaceut Co Ltd Quinoline-3-carboxylic acid derivative, its preparation, and pharmaceutical composition containig the same
JPS54141286A (en) * 1978-04-14 1979-11-02 Matsuo Kogyo Spool detachable system in spinning reel for fishing
JPS54138582A (en) * 1978-04-19 1979-10-27 Kyorin Seiyaku Kk Substituted quinolinecarboxylic acid
JPS5540656A (en) * 1978-09-19 1980-03-22 Kyorin Pharmaceut Co Ltd Substituted quinoline-carboxylic acid derivative
JPS5845426B2 (ja) * 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体

Also Published As

Publication number Publication date
AR226917A1 (es) 1982-08-31
NZ198295A (en) 1984-02-03
ES505207A0 (es) 1982-12-16
FI77854C (fi) 1989-05-10
SE442402B (sv) 1985-12-23
JPS5762259A (en) 1982-04-15
BE890223A (fr) 1982-01-04
NO157699C (no) 1988-05-04
LU83609A1 (fr) 1982-01-21
AU540205B2 (en) 1984-11-08
ES514699A0 (es) 1983-05-01
FR2489821B1 (fr) 1986-01-10
NO812686L (no) 1982-03-08
IT1168168B (it) 1987-05-20
JPH0130823B2 (ko) 1989-06-22
KR870001944B1 (ko) 1987-10-23
ATA358881A (de) 1985-08-15
DK380681A (da) 1982-03-06
PT73571B (en) 1982-11-09
US4472579A (en) 1984-09-18
DE3135125C2 (ko) 1988-10-27
CA1214466A (en) 1986-11-25
ES8305752A1 (es) 1983-05-01
DE3135125A1 (de) 1982-06-03
GB2085875B (en) 1984-06-13
FR2489821A1 (fr) 1982-03-12
PT73571A (en) 1981-09-01
ZA815207B (en) 1982-07-28
FI77854B (fi) 1989-01-31
IT8123799A0 (it) 1981-09-04
CH646697A5 (de) 1984-12-14
SE8105102L (sv) 1982-03-06
GR74304B (ko) 1984-06-22
GB2085875A (en) 1982-05-06
DK154763B (da) 1988-12-19
IN155106B (ko) 1985-01-05
FI812538L (fi) 1982-03-06
AT380009B (de) 1986-03-25
PH17837A (en) 1985-01-07
NL8103679A (nl) 1982-04-01
NO157699B (no) 1988-01-25
DK154763C (da) 1989-06-26
AU7461181A (en) 1982-03-11
NL193375C (nl) 1999-08-03
HU187356B (en) 1985-12-28
ES8301965A1 (es) 1982-12-16
IE812028L (en) 1982-03-05
IE51540B1 (en) 1987-01-07
NL193375B (nl) 1999-04-01
MX7101E (es) 1987-06-24

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