ES8404354A1 - Un procedimiento para la preparacion de un nuevo compuesto biciclico. - Google Patents

Un procedimiento para la preparacion de un nuevo compuesto biciclico.

Info

Publication number
ES8404354A1
ES8404354A1 ES520567A ES520567A ES8404354A1 ES 8404354 A1 ES8404354 A1 ES 8404354A1 ES 520567 A ES520567 A ES 520567A ES 520567 A ES520567 A ES 520567A ES 8404354 A1 ES8404354 A1 ES 8404354A1
Authority
ES
Spain
Prior art keywords
group
substituent
optionally
phenyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES520567A
Other languages
English (en)
Other versions
ES520567A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES520567A0 publication Critical patent/ES520567A0/es
Publication of ES8404354A1 publication Critical patent/ES8404354A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UN COMPUESTO BICICLICO, DE FORMULA GENERAL (I), EN LA QUE R Y R REPRESENTAN CADA UNO DE ELLOS UN GRUPO ALCOHILO DE 1 A 6 ATOMOS DE CARBONO; Y R ES UN GRUPO HIDROXI ESTERIFICADO DE FORMULA: -OCO-R, QUE REPRESENTA UN GRUPO FENIL-ACETOXI O UN GRUPO CANIMOILOXI CON UN SUSTITUYENTE HALOGENO O UNO O MAS SUSTITUYENTES ALCOXI, Y SUS SALES DE ACIDO FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R Y R TIENEN LOS SIGNIFICADOS INDICADOS, CON UN ACIDO CARBOXILICO DEFORMULA: R - COOH, EN DONDE EL GRUPO -O-CO-R TIENE EL SIGNIFICADO MENCIONADO, O CON UN DERIVADO REACTIVO DEL MISMO, Y EN PRESENCIA DE UN AGENTE DE FIJACION DE ACIDO O DE UN METAL ALCALINO O DE UNA SUSTANCIA QUE CATALICE LA TRANSESTERIFICACION.
ES520567A 1981-07-20 1983-03-14 Un procedimiento para la preparacion de un nuevo compuesto biciclico. Expired ES8404354A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU812112A HU184960B (en) 1981-07-20 1981-07-20 Process for preparing new derivatives of 3,7-diazabicyclo/3.3.1/ nonane

Publications (2)

Publication Number Publication Date
ES520567A0 ES520567A0 (es) 1984-05-01
ES8404354A1 true ES8404354A1 (es) 1984-05-01

Family

ID=10957812

Family Applications (2)

Application Number Title Priority Date Filing Date
ES514126A Granted ES514126A0 (es) 1981-07-20 1982-07-19 "un procedimiento para la preparacion de un nuevo compuesto biciclico".
ES520567A Expired ES8404354A1 (es) 1981-07-20 1983-03-14 Un procedimiento para la preparacion de un nuevo compuesto biciclico.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES514126A Granted ES514126A0 (es) 1981-07-20 1982-07-19 "un procedimiento para la preparacion de un nuevo compuesto biciclico".

Country Status (31)

Country Link
US (1) US4451473A (es)
JP (1) JPS5849383A (es)
AR (1) AR230447A1 (es)
AT (1) AT379809B (es)
AU (1) AU552770B2 (es)
BE (1) BE893891A (es)
CA (1) CA1254208A (es)
CH (1) CH653032A5 (es)
CS (1) CS235302B2 (es)
DD (1) DD202575A5 (es)
DE (1) DE3226921C2 (es)
DK (1) DK160875C (es)
ES (2) ES514126A0 (es)
FI (1) FI71320C (es)
FR (1) FR2510575B1 (es)
GB (1) GB2102801B (es)
GR (1) GR76874B (es)
HU (1) HU184960B (es)
IL (1) IL66277A (es)
IN (1) IN155994B (es)
IT (1) IT1190920B (es)
MX (1) MX159288A (es)
NL (1) NL8202908A (es)
NO (1) NO157421C (es)
PH (1) PH18502A (es)
PL (2) PL135878B1 (es)
PT (1) PT75265B (es)
SE (1) SE450704B (es)
SU (2) SU1222197A3 (es)
YU (1) YU45867B (es)
ZA (1) ZA824809B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5036153A (en) * 1989-05-11 1991-07-30 Braish Tamim F Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates
GB9726630D0 (en) 1997-12-18 1998-02-18 Glaxo Group Ltd Kv2.1 Antagonists
AU1996301A (en) * 1999-12-14 2001-06-25 Neurosearch A/S Novel heteroaryl-diazabicycloalkanes
PL1731518T3 (pl) 2004-03-31 2014-11-28 Nippon Soda Co Cykliczny związek aminowy oraz środek zwalczający szkodniki
JP4871289B2 (ja) * 2005-10-06 2012-02-08 日本曹達株式会社 環状アミン化合物および有害生物防除剤
UA86328C2 (uk) * 2005-10-06 2009-04-10 Ниппон Сода Ко., Лтд. Циклічні амінові сполуки, засіб для боротьби зі шкідниками
PL2152670T3 (pl) * 2007-04-27 2014-05-30 Idorsia Pharmaceuticals Ltd Mostkowane sześcioczłonowe związki pierścieniowe

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078272A (en) * 1963-02-19 N-aza-bicyclo-alkylene-imino
DE2428792A1 (de) * 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
DE2726571A1 (de) * 1977-06-13 1978-12-21 Basf Ag Neue bispidinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten

Also Published As

Publication number Publication date
PL244329A1 (en) 1984-05-07
SE8204393L (sv) 1983-01-21
AU8617682A (en) 1983-01-27
DK160875C (da) 1991-10-14
AU552770B2 (en) 1986-06-19
AT379809B (de) 1986-03-10
JPS5849383A (ja) 1983-03-23
AR230447A1 (es) 1984-04-30
NO822485L (no) 1983-01-21
FR2510575A1 (fr) 1983-02-04
DK319982A (da) 1983-01-21
FI71320B (fi) 1986-09-09
DD202575A5 (de) 1983-09-21
GB2102801A (en) 1983-02-09
IL66277A0 (en) 1982-11-30
IT1190920B (it) 1988-02-24
YU45867B (sh) 1992-09-07
PT75265B (en) 1984-07-02
SU1272990A3 (ru) 1986-11-23
ES8401972A1 (es) 1984-01-01
MX159288A (es) 1989-05-12
IN155994B (es) 1985-04-20
FI71320C (fi) 1986-12-19
NO157421B (no) 1987-12-07
SE8204393D0 (sv) 1982-07-19
DE3226921C2 (de) 1994-03-10
IL66277A (en) 1985-08-30
PH18502A (en) 1985-08-02
FR2510575B1 (fr) 1986-02-07
US4451473A (en) 1984-05-29
JPH0352465B2 (es) 1991-08-12
DE3226921A1 (de) 1983-02-10
IT8222448A1 (it) 1984-01-19
DK160875B (da) 1991-04-29
HU184960B (en) 1984-11-28
IT8222448A0 (it) 1982-07-19
PL135814B1 (en) 1985-12-31
YU157182A (en) 1986-10-31
PT75265A (en) 1982-08-01
FI822526A0 (fi) 1982-07-15
GB2102801B (en) 1985-03-27
FI822526L (fi) 1983-01-21
ES520567A0 (es) 1984-05-01
NL8202908A (nl) 1983-02-16
PL237566A1 (en) 1984-03-12
CA1254208A (en) 1989-05-16
ES514126A0 (es) 1984-01-01
SU1222197A3 (ru) 1986-03-30
GR76874B (es) 1984-09-04
ATA272382A (de) 1985-07-15
CS235302B2 (en) 1985-05-15
CH653032A5 (de) 1985-12-13
PL135878B1 (en) 1985-12-31
ZA824809B (en) 1983-04-27
BE893891A (fr) 1983-01-20
NO157421C (no) 1988-03-16
SE450704B (sv) 1987-07-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201