ES8307006A1 - Procedimiento de preparar nuevos derivados de aprovincaminol. - Google Patents
Procedimiento de preparar nuevos derivados de aprovincaminol.Info
- Publication number
- ES8307006A1 ES8307006A1 ES509419A ES509419A ES8307006A1 ES 8307006 A1 ES8307006 A1 ES 8307006A1 ES 509419 A ES509419 A ES 509419A ES 509419 A ES509419 A ES 509419A ES 8307006 A1 ES8307006 A1 ES 8307006A1
- Authority
- ES
- Spain
- Prior art keywords
- aprovincaminol
- procedure
- hydrogen
- pharmaceutically acceptable
- addition salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 4
- SJSOFNCYXJUNBT-UHFFFAOYSA-N 3,4,5-trimethoxybenzoic acid Chemical compound COC1=CC(C(O)=O)=CC(OC)=C1OC SJSOFNCYXJUNBT-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000002828 nitro derivatives Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- IWPZKOJSYQZABD-UHFFFAOYSA-N 3,4,5-trimethoxybenzoic acid Natural products COC1=CC(OC)=CC(C(O)=O)=C1 IWPZKOJSYQZABD-UHFFFAOYSA-N 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000802 nitrating effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU81323A HU183325B (en) | 1981-02-11 | 1981-02-11 | Process for preparing new apovincaminol-3',4',5'-trimethoxy-benzoates substituted with a nitro group |
| HU81322A HU183324B (en) | 1981-02-11 | 1981-02-11 | Process for preparing new apovincaminol-3',4',5'-trimethoxy-benzoate and acid addition salts thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES509419A0 ES509419A0 (es) | 1983-07-01 |
| ES8307006A1 true ES8307006A1 (es) | 1983-07-01 |
Family
ID=26317194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509419A Expired ES8307006A1 (es) | 1981-02-11 | 1982-02-08 | Procedimiento de preparar nuevos derivados de aprovincaminol. |
Country Status (19)
| Country | Link |
|---|---|
| AR (1) | AR227574A1 (en, 2012) |
| AT (1) | AT386203B (en, 2012) |
| AU (1) | AU544455B2 (en, 2012) |
| CA (1) | CA1202028A (en, 2012) |
| CH (1) | CH651038A5 (en, 2012) |
| DD (1) | DD202570A5 (en, 2012) |
| DE (1) | DE3204509A1 (en, 2012) |
| DK (1) | DK151023C (en, 2012) |
| ES (1) | ES8307006A1 (en, 2012) |
| FI (1) | FI70215C (en, 2012) |
| FR (1) | FR2499571B1 (en, 2012) |
| GB (1) | GB2094787B (en, 2012) |
| GR (1) | GR75857B (en, 2012) |
| IL (1) | IL64808A (en, 2012) |
| IT (1) | IT1157301B (en, 2012) |
| NL (1) | NL8200490A (en, 2012) |
| NO (1) | NO820394L (en, 2012) |
| SE (1) | SE449863B (en, 2012) |
| SU (1) | SU1093249A3 (en, 2012) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU192013B (en) * | 1984-04-25 | 1987-04-28 | Richter Gedeon Vegyeszet | Process for production of new aporincavinol esther derivatives |
| HU193772B (en) * | 1985-06-12 | 1987-11-30 | Richter Gedeon Vegyeszet | Process for producing new nitro-bis-indole derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2035784A1 (en) * | 1969-03-27 | 1970-12-24 | Olivier Louisette | Vincamine derivs with therapeutic propert- - ies |
| HU170888B (hu) * | 1975-06-10 | 1977-09-28 | Richter Gedeon Vegyeszet | Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh eburnameninov |
| HU171662B (hu) * | 1975-07-18 | 1978-02-28 | Richter Gedeon Vegyeszet | Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov |
| HU177370B (en) * | 1977-07-27 | 1981-09-28 | Richter Gedeon Vegyeszet | Process for producing new bracket-cross-bracket-vincaminol-esters |
-
1982
- 1982-01-18 SE SE8200248A patent/SE449863B/sv not_active IP Right Cessation
- 1982-01-19 IL IL64808A patent/IL64808A/xx unknown
- 1982-01-25 CA CA000394857A patent/CA1202028A/en not_active Expired
- 1982-01-26 AT AT0026082A patent/AT386203B/de not_active IP Right Cessation
- 1982-01-29 CH CH565/82A patent/CH651038A5/de not_active IP Right Cessation
- 1982-02-03 FI FI820339A patent/FI70215C/fi not_active IP Right Cessation
- 1982-02-08 ES ES509419A patent/ES8307006A1/es not_active Expired
- 1982-02-08 GR GR67242A patent/GR75857B/el unknown
- 1982-02-09 FR FR8202044A patent/FR2499571B1/fr not_active Expired
- 1982-02-09 NL NL8200490A patent/NL8200490A/nl not_active Application Discontinuation
- 1982-02-10 AU AU80338/82A patent/AU544455B2/en not_active Ceased
- 1982-02-10 DD DD82237319A patent/DD202570A5/de not_active IP Right Cessation
- 1982-02-10 SU SU823390301A patent/SU1093249A3/ru active
- 1982-02-10 IT IT19587/82A patent/IT1157301B/it active
- 1982-02-10 DE DE19823204509 patent/DE3204509A1/de active Granted
- 1982-02-10 DK DK057782A patent/DK151023C/da not_active IP Right Cessation
- 1982-02-10 NO NO820394A patent/NO820394L/no unknown
- 1982-02-11 AR AR288399A patent/AR227574A1/es active
- 1982-02-11 GB GB8204018A patent/GB2094787B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2094787B (en) | 1984-10-24 |
| ES509419A0 (es) | 1983-07-01 |
| IT1157301B (it) | 1987-02-11 |
| SE8200248L (sv) | 1982-08-12 |
| NO820394L (no) | 1982-08-12 |
| GB2094787A (en) | 1982-09-22 |
| DK151023B (da) | 1987-10-12 |
| DE3204509C2 (en, 2012) | 1990-10-04 |
| CH651038A5 (de) | 1985-08-30 |
| DK151023C (da) | 1988-06-27 |
| DK57782A (da) | 1982-08-12 |
| GR75857B (en, 2012) | 1984-08-02 |
| AU544455B2 (en) | 1985-05-30 |
| IL64808A0 (en) | 1982-03-31 |
| SU1093249A3 (ru) | 1984-05-15 |
| ATA26082A (de) | 1987-12-15 |
| AU8033882A (en) | 1982-08-19 |
| IL64808A (en) | 1984-12-31 |
| FR2499571B1 (fr) | 1986-03-28 |
| FI70215B (fi) | 1986-02-28 |
| NL8200490A (nl) | 1982-09-01 |
| FR2499571A1 (fr) | 1982-08-13 |
| FI70215C (fi) | 1986-09-15 |
| IT8219587A0 (it) | 1982-02-10 |
| AT386203B (de) | 1988-07-25 |
| CA1202028A (en) | 1986-03-18 |
| DE3204509A1 (de) | 1982-08-26 |
| SE449863B (sv) | 1987-05-25 |
| FI820339L (fi) | 1982-08-12 |
| AR227574A1 (es) | 1982-11-15 |
| DD202570A5 (de) | 1983-09-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |
Effective date: 19960506 |