ES482156A1 - Un procedimiento para la preparacion de nuevos derivados de-fenetanolamina. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de-fenetanolamina.Info
- Publication number
- ES482156A1 ES482156A1 ES482156A ES482156A ES482156A1 ES 482156 A1 ES482156 A1 ES 482156A1 ES 482156 A ES482156 A ES 482156A ES 482156 A ES482156 A ES 482156A ES 482156 A1 ES482156 A1 ES 482156A1
- Authority
- ES
- Spain
- Prior art keywords
- phenethanolamines
- formulations
- preparation
- methylaminocarbonyl
- aminocarbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/06—Preparation of carboxylic acid nitriles from N-formylated amino compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
Abstract
Procedimientos para la preparación de nuevos derivados de fenetanolamina, útiles para controlar el peso de los mamíferos. Se han realizado extensas investigaciones en el campo de los derivados de beta-feniletilamina, como las catecolaminas. Por ejemplo, se ha estudiado mucho la catecolamina natural, epinefrina. La epinefrina es un potente fármaco simpatomimético y un intenso estimulante cardiaco. Sin embargo, el uso de la epinefrina es limitado debido a sus efectos secundarios indeseables entre los que se encuentran temor, ansiedad, temblores, tensión nerviosa, dolores de cabeza con latidos, mayor presión sanguínea, vértigos, dificultades respiratorias y palpitaciones así como debido a su corta duración de acción.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92167078A | 1978-07-03 | 1978-07-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES482156A1 true ES482156A1 (es) | 1980-08-16 |
Family
ID=25445792
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES482155A Expired ES482155A1 (es) | 1978-07-03 | 1979-07-03 | Un procedimiento para la preparacion de derivados de feneta-nolamina. |
ES482156A Expired ES482156A1 (es) | 1978-07-03 | 1979-07-03 | Un procedimiento para la preparacion de nuevos derivados de-fenetanolamina. |
ES490215A Expired ES8104190A1 (es) | 1978-07-03 | 1980-04-01 | Un procedimiento para la preparacion de derivados de feneta-nolamina |
ES490214A Expired ES8104189A1 (es) | 1978-07-03 | 1980-04-01 | Un procedimiento para la preparacion de derivados de feneta-nolamina |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES482155A Expired ES482155A1 (es) | 1978-07-03 | 1979-07-03 | Un procedimiento para la preparacion de derivados de feneta-nolamina. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES490215A Expired ES8104190A1 (es) | 1978-07-03 | 1980-04-01 | Un procedimiento para la preparacion de derivados de feneta-nolamina |
ES490214A Expired ES8104189A1 (es) | 1978-07-03 | 1980-04-01 | Un procedimiento para la preparacion de derivados de feneta-nolamina |
Country Status (31)
Country | Link |
---|---|
EP (3) | EP0048037A1 (es) |
JP (2) | JPS559097A (es) |
KR (1) | KR880002310B1 (es) |
AR (4) | AR225744A1 (es) |
AT (2) | AT367025B (es) |
AU (2) | AU523720B2 (es) |
BE (2) | BE877393A (es) |
BG (4) | BG31646A3 (es) |
CA (2) | CA1142954A (es) |
CH (2) | CH643529A5 (es) |
CS (4) | CS208662B2 (es) |
DD (2) | DD144761A5 (es) |
DE (2) | DE2964604D1 (es) |
DK (2) | DK160936C (es) |
EG (1) | EG14238A (es) |
ES (4) | ES482155A1 (es) |
FI (2) | FI792082A (es) |
FR (3) | FR2430410B1 (es) |
GB (3) | GB2028799B (es) |
GR (2) | GR72940B (es) |
HU (2) | HU179172B (es) |
IE (2) | IE48769B1 (es) |
IL (2) | IL57671A (es) |
LU (2) | LU81457A1 (es) |
NZ (2) | NZ190861A (es) |
PH (2) | PH14522A (es) |
PL (4) | PL121297B1 (es) |
PT (2) | PT69843A (es) |
RO (4) | RO83052B (es) |
SU (4) | SU849997A3 (es) |
ZA (2) | ZA793297B (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2965655D1 (en) * | 1978-06-28 | 1983-07-21 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
EP0028105B1 (en) * | 1979-10-25 | 1983-01-19 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
EP0029320B1 (en) * | 1979-11-15 | 1985-07-10 | Beecham Group Plc | Secondary ethanol amines, their preparation and their use in pharmaceutical compositions |
DE3161165D1 (en) * | 1980-05-08 | 1983-11-17 | Beecham Group Plc | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions |
DE3264364D1 (en) * | 1981-03-06 | 1985-08-01 | Beecham Group Plc | Arylethanol amine derivatives, their preparation and use in pharmaceutical compositions |
DE3260490D1 (en) * | 1981-03-31 | 1984-09-06 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
EP0070133B1 (en) * | 1981-07-11 | 1986-05-14 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
EP0089154A3 (en) * | 1982-03-12 | 1984-08-08 | Beecham Group Plc | Ethanolamine derivatives, their preparation and use in pharmaceutical compositions |
CA1219865A (en) * | 1982-05-14 | 1987-03-31 | Leo Alig | Aziridine phenethanolamine derivatives |
CA1258454A (en) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
JPS5980640A (ja) * | 1982-09-27 | 1984-05-10 | イーライ・リリー・アンド・カンパニー | 2−ヒドロキシ−2−フエニルエチルアミン類の製造方法 |
PL144053B1 (en) * | 1983-01-31 | 1988-04-30 | Lilly Co Eli | Method of stimulating growth of domesticated animals,improving effectivness of food utilization ba domesticated animals and improving leanness of domesticated animals and fodder pre-mixture |
CA1262729A (en) * | 1983-10-19 | 1989-11-07 | Leo Alig | Phenoxypropanolamines |
US5166218A (en) * | 1983-10-19 | 1992-11-24 | Hoffmann-La Roche Inc. | Phenoxypropanolamines and pharmaceutical compositions thereof |
US4602044A (en) * | 1983-12-19 | 1986-07-22 | Eli Lilly And Company | β-phenethanolamine antiobesity agents |
EP0151513A1 (en) * | 1984-01-12 | 1985-08-14 | Eli Lilly And Company | Inotropic agent |
GB8505284D0 (en) * | 1985-03-01 | 1985-04-03 | Beecham Group Plc | Growth promoters |
PT82120B (en) * | 1985-03-01 | 1988-06-16 | Beecham Group Plc | Process for preparing veterinary formulations containing ethanolamine derivatives |
IT1204416B (it) * | 1986-06-27 | 1989-03-01 | Midy Spa | Medicamenti a base di analoghi di feniletanolammine per il trattamento di disturbi gastro-intestinali ed uterini |
JP2837408B2 (ja) * | 1987-05-30 | 1998-12-16 | 鐘紡株式会社 | アクリル系繊維の処理方法 |
US5135955A (en) * | 1988-04-25 | 1992-08-04 | Eli Lilly And Company | Propanamine derivatives |
FI892341A (fi) * | 1988-06-10 | 1989-12-11 | Hoffmann La Roche | Propanolaminderivat. |
US5191112A (en) * | 1989-10-17 | 1993-03-02 | Nissan Chemical Industries, Ltd. | Process for optical resolution of (±)-2-(3-benzoyl)-phenylpropionic acid |
US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
KR100251995B1 (ko) * | 1991-08-23 | 2000-06-01 | 젠센 제임스 유. | 칼슘 수용체 활성 분자 |
US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
US5321036A (en) * | 1993-02-10 | 1994-06-14 | Bristol-Myers Squibb Company | Thiazole and oxazole-based β3 adrenergic receptor agonists |
US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
CN1312116C (zh) | 1994-10-21 | 2007-04-25 | Nps药物有限公司 | 钙受体活性化合物 |
DE69722934T2 (de) | 1996-05-01 | 2004-05-27 | NPS Pharmaceuticals, Inc., Salt Lake City | Verbindungen , die auf anorganische ionen-rezeptoren wirken |
US7321065B2 (en) * | 2003-04-18 | 2008-01-22 | The Regents Of The University Of California | Thyronamine derivatives and analogs and methods of use thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL56308C (es) * | 1941-03-15 | |||
GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
GB1301134A (en) | 1970-07-18 | 1972-12-29 | Pfizer Ltd | SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES |
BE788850A (fr) * | 1972-09-15 | 1973-03-15 | Hoffmann La Roche | Derives d'acide benzoique |
IE39247B1 (en) * | 1973-05-07 | 1978-08-30 | Allen & Hanburys Ltd | Substituted benzamides |
US4000192A (en) * | 1973-05-07 | 1976-12-28 | Allen & Hanburys Limited | Pharmacologically active compounds |
NZ190854A (en) * | 1978-06-28 | 1984-10-19 | Beecham Group Ltd | 2-hydroxy-2-phenyl ethylamine derivatives;pharmaceutical compositions |
CA1145766A (en) * | 1978-07-03 | 1983-05-03 | Jack Mills | Optically active phenethanolamines and method for increasing cardiac contractility |
-
1979
- 1979-06-26 IL IL57671A patent/IL57671A/xx unknown
- 1979-06-26 DK DK268679A patent/DK160936C/da not_active IP Right Cessation
- 1979-06-26 IL IL57672A patent/IL57672A/xx unknown
- 1979-06-26 CA CA000330553A patent/CA1142954A/en not_active Expired
- 1979-06-26 DK DK268779A patent/DK268779A/da not_active Application Discontinuation
- 1979-06-26 CA CA000330554A patent/CA1145767A/en not_active Expired
- 1979-06-27 NZ NZ190861A patent/NZ190861A/xx unknown
- 1979-06-27 EG EG387/78A patent/EG14238A/xx active
- 1979-06-27 PH PH22702A patent/PH14522A/en unknown
- 1979-06-27 PH PH22698A patent/PH15275A/en unknown
- 1979-06-27 NZ NZ190863A patent/NZ190863A/xx unknown
- 1979-06-28 PT PT69843A patent/PT69843A/pt unknown
- 1979-06-28 AU AU48487/79A patent/AU523720B2/en not_active Expired
- 1979-06-28 PT PT69839A patent/PT69839A/pt unknown
- 1979-06-28 AU AU48489/79A patent/AU523721B2/en not_active Ceased
- 1979-06-29 HU HU79EI868A patent/HU179172B/hu not_active IP Right Cessation
- 1979-06-29 HU HU79EI867A patent/HU179171B/hu unknown
- 1979-06-29 FR FR7916993A patent/FR2430410B1/fr not_active Expired
- 1979-06-29 FR FR7916994A patent/FR2430411A1/fr active Granted
- 1979-07-02 GB GB7922952A patent/GB2028799B/en not_active Expired
- 1979-07-02 FI FI792082A patent/FI792082A/fi not_active Application Discontinuation
- 1979-07-02 CS CS794631A patent/CS208662B2/cs unknown
- 1979-07-02 BE BE1/9444A patent/BE877393A/fr not_active IP Right Cessation
- 1979-07-02 RO RO105065A patent/RO83052B/ro unknown
- 1979-07-02 LU LU81457A patent/LU81457A1/xx unknown
- 1979-07-02 CH CH616279A patent/CH643529A5/fr not_active IP Right Cessation
- 1979-07-02 BG BG7945342A patent/BG31646A3/xx unknown
- 1979-07-02 EP EP81109789A patent/EP0048037A1/en not_active Ceased
- 1979-07-02 JP JP8489179A patent/JPS559097A/ja active Pending
- 1979-07-02 GB GB7922955A patent/GB2028802B/en not_active Expired
- 1979-07-02 DE DE7979301278T patent/DE2964604D1/de not_active Expired
- 1979-07-02 FI FI792081A patent/FI792081A/fi not_active Application Discontinuation
- 1979-07-02 JP JP8489079A patent/JPS559096A/ja active Granted
- 1979-07-02 GB GB08135768A patent/GB2101582B/en not_active Expired
- 1979-07-02 LU LU81458A patent/LU81458A1/xx unknown
- 1979-07-02 EP EP79301278A patent/EP0006766B1/en not_active Expired
- 1979-07-02 CS CS794631A patent/CS208664B2/cs unknown
- 1979-07-02 BG BG7944166A patent/BG31645A3/xx unknown
- 1979-07-02 BG BG7944169A patent/BG31375A3/xx unknown
- 1979-07-02 SU SU792782302A patent/SU849997A3/ru active
- 1979-07-02 BG BG7945343A patent/BG31647A3/xx unknown
- 1979-07-02 SU SU792786202A patent/SU965350A3/ru active
- 1979-07-02 RO RO105064A patent/RO83051B/ro unknown
- 1979-07-02 CH CH616179A patent/CH642618A5/fr not_active IP Right Cessation
- 1979-07-02 CS CS794631A patent/CS208663B2/cs unknown
- 1979-07-02 GR GR59490A patent/GR72940B/el unknown
- 1979-07-02 RO RO7998013A patent/RO77732A/ro unknown
- 1979-07-02 CS CS794632A patent/CS209815B2/cs unknown
- 1979-07-02 GR GR59491A patent/GR74524B/el unknown
- 1979-07-02 BE BE1/9445A patent/BE877394A/fr not_active IP Right Cessation
- 1979-07-02 RO RO7998009A patent/RO77728A/ro unknown
- 1979-07-02 EP EP79301279A patent/EP0007204B1/en not_active Expired
- 1979-07-02 DE DE7979301279T patent/DE2964091D1/de not_active Expired
- 1979-07-03 PL PL1979216811A patent/PL121297B1/pl unknown
- 1979-07-03 AR AR277166A patent/AR225744A1/es active
- 1979-07-03 ES ES482155A patent/ES482155A1/es not_active Expired
- 1979-07-03 ES ES482156A patent/ES482156A1/es not_active Expired
- 1979-07-03 AT AT0463679A patent/AT367025B/de not_active IP Right Cessation
- 1979-07-03 DD DD79214069A patent/DD144761A5/de unknown
- 1979-07-03 PL PL1979226370A patent/PL117997B1/pl unknown
- 1979-07-03 DD DD79214070A patent/DD144762A5/de unknown
- 1979-07-03 ZA ZA793297A patent/ZA793297B/xx unknown
- 1979-07-03 PL PL1979226371A patent/PL117996B1/pl unknown
- 1979-07-03 AT AT0463579A patent/AT372937B/de not_active IP Right Cessation
- 1979-07-03 AR AR277167A patent/AR229080A1/es active
- 1979-07-03 PL PL1979216814A patent/PL117551B1/pl unknown
- 1979-07-03 ZA ZA793296A patent/ZA793296B/xx unknown
- 1979-08-08 IE IE1227/79A patent/IE48769B1/en not_active IP Right Cessation
- 1979-08-08 IE IE1228/79A patent/IE48586B1/en unknown
-
1980
- 1980-04-01 ES ES490215A patent/ES8104190A1/es not_active Expired
- 1980-04-01 ES ES490214A patent/ES8104189A1/es not_active Expired
- 1980-04-24 FR FR8009239A patent/FR2450806B1/fr not_active Expired
- 1980-08-13 SU SU802955864A patent/SU957761A3/ru active
- 1980-08-13 SU SU802957757A patent/SU1007554A3/ru active
- 1980-10-29 AR AR283050A patent/AR227165A1/es active
- 1980-10-29 AR AR283051A patent/AR231434A1/es active
-
1982
- 1982-02-12 KR KR8200619A patent/KR880002310B1/ko active
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