RO83052B - Procedeu pentru prepararea unor derivati de fenetanolamina - Google Patents

Procedeu pentru prepararea unor derivati de fenetanolamina

Info

Publication number
RO83052B
RO83052B RO105065A RO10506579A RO83052B RO 83052 B RO83052 B RO 83052B RO 105065 A RO105065 A RO 105065A RO 10506579 A RO10506579 A RO 10506579A RO 83052 B RO83052 B RO 83052B
Authority
RO
Romania
Prior art keywords
phenetanoleamine
derivatives
preparation
phenetanoleamine derivatives
Prior art date
Application number
RO105065A
Other languages
English (en)
Other versions
RO83052A (ro
Inventor
Jack Mills
Klaus Kurt Schmiegel
Walter Norman Shaw
Original Assignee
Eli Lilly And Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co filed Critical Eli Lilly And Co
Publication of RO83052A publication Critical patent/RO83052A/ro
Publication of RO83052B publication Critical patent/RO83052B/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/06Preparation of carboxylic acid nitriles from N-formylated amino compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/38Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/04Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
RO105065A 1978-07-03 1979-07-02 Procedeu pentru prepararea unor derivati de fenetanolamina RO83052B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92167078A 1978-07-03 1978-07-03

Publications (2)

Publication Number Publication Date
RO83052A RO83052A (ro) 1984-02-21
RO83052B true RO83052B (ro) 1984-02-28

Family

ID=25445792

Family Applications (4)

Application Number Title Priority Date Filing Date
RO7998009A RO77728A (ro) 1978-07-03 1979-07-02 Procedeu pentru prepararea unor derivati de fenetanolamina
RO7998013A RO77732A (ro) 1978-07-03 1979-07-02 Procedeu pentru prepararea unor derivati de fenetanolamina
RO105065A RO83052B (ro) 1978-07-03 1979-07-02 Procedeu pentru prepararea unor derivati de fenetanolamina
RO105064A RO83051B (ro) 1978-07-03 1979-07-02 Procedeu pentru prepararea unor derivati de fenetanolamina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
RO7998009A RO77728A (ro) 1978-07-03 1979-07-02 Procedeu pentru prepararea unor derivati de fenetanolamina
RO7998013A RO77732A (ro) 1978-07-03 1979-07-02 Procedeu pentru prepararea unor derivati de fenetanolamina

Family Applications After (1)

Application Number Title Priority Date Filing Date
RO105064A RO83051B (ro) 1978-07-03 1979-07-02 Procedeu pentru prepararea unor derivati de fenetanolamina

Country Status (31)

Country Link
EP (3) EP0048037A1 (ro)
JP (2) JPS559097A (ro)
KR (1) KR880002310B1 (ro)
AR (4) AR225744A1 (ro)
AT (2) AT367025B (ro)
AU (2) AU523720B2 (ro)
BE (2) BE877394A (ro)
BG (4) BG31647A3 (ro)
CA (2) CA1142954A (ro)
CH (2) CH643529A5 (ro)
CS (4) CS208663B2 (ro)
DD (2) DD144762A5 (ro)
DE (2) DE2964091D1 (ro)
DK (2) DK268779A (ro)
EG (1) EG14238A (ro)
ES (4) ES482156A1 (ro)
FI (2) FI792082A (ro)
FR (3) FR2430411A1 (ro)
GB (3) GB2028799B (ro)
GR (2) GR72940B (ro)
HU (2) HU179172B (ro)
IE (2) IE48586B1 (ro)
IL (2) IL57672A (ro)
LU (2) LU81457A1 (ro)
NZ (2) NZ190861A (ro)
PH (2) PH14522A (ro)
PL (4) PL117551B1 (ro)
PT (2) PT69839A (ro)
RO (4) RO77728A (ro)
SU (4) SU849997A3 (ro)
ZA (2) ZA793297B (ro)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
ATE2265T1 (de) * 1979-10-25 1983-02-15 Beecham Group Plc Sekundaere amine, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.
DE3070865D1 (en) * 1979-11-15 1985-08-14 Beecham Group Plc Secondary ethanol amines, their preparation and their use in pharmaceutical compositions
DE3161165D1 (en) * 1980-05-08 1983-11-17 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
DE3264364D1 (en) * 1981-03-06 1985-08-01 Beecham Group Plc Arylethanol amine derivatives, their preparation and use in pharmaceutical compositions
DE3260490D1 (en) * 1981-03-31 1984-09-06 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
EP0070133B1 (en) * 1981-07-11 1986-05-14 Beecham Group Plc Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application
EP0089154A3 (en) * 1982-03-12 1984-08-08 Beecham Group Plc Ethanolamine derivatives, their preparation and use in pharmaceutical compositions
CA1219865A (en) * 1982-05-14 1987-03-31 Leo Alig Aziridine phenethanolamine derivatives
CA1258454A (en) * 1982-08-10 1989-08-15 Leo Alig Phenethanolamines
IL69788A (en) * 1982-09-27 1987-01-30 Lilly Co Eli Process for preparing 2-hydroxy-2-phenylethylamines,and novel silylated intermediates therefor
FI81713C (fi) * 1983-01-31 1990-12-10 Lilly Co Eli Foerfarande och djurfoderpremix foer befraemjande av tillvaexten, foerbaettring av utnyttjandegraden av foder eller minskning av fetthalten i koett hos ett husdjur.
US5166218A (en) * 1983-10-19 1992-11-24 Hoffmann-La Roche Inc. Phenoxypropanolamines and pharmaceutical compositions thereof
CA1262729A (en) * 1983-10-19 1989-11-07 Leo Alig Phenoxypropanolamines
US4602044A (en) * 1983-12-19 1986-07-22 Eli Lilly And Company β-phenethanolamine antiobesity agents
EP0151513A1 (en) * 1984-01-12 1985-08-14 Eli Lilly And Company Inotropic agent
ES8800842A1 (es) * 1985-03-01 1987-12-01 Beecham Group Plc Un procedimiento para preparar una formulacion veterinariamente aceptable de ariletanolaminas promotora del crecimiento.
GB8505284D0 (en) * 1985-03-01 1985-04-03 Beecham Group Plc Growth promoters
IT1204416B (it) * 1986-06-27 1989-03-01 Midy Spa Medicamenti a base di analoghi di feniletanolammine per il trattamento di disturbi gastro-intestinali ed uterini
JP2837408B2 (ja) * 1987-05-30 1998-12-16 鐘紡株式会社 アクリル系繊維の処理方法
US5135955A (en) * 1988-04-25 1992-08-04 Eli Lilly And Company Propanamine derivatives
FI892341A (fi) * 1988-06-10 1989-12-11 Hoffmann La Roche Propanolaminderivat.
CA2023954C (en) * 1989-10-17 1999-05-04 Hiroyuki Nohira Process for the optical resolution of 2-(3-benzoyl) phenylpropionic acid
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5763569A (en) * 1991-08-23 1998-06-09 The Brigham And Women's Hospital, Inc Calcium receptor-active molecules
US5858684A (en) * 1991-08-23 1999-01-12 The Brigham And Women's Hospital, Inc. Method of screening calcium receptor-active molecules
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
DK1281702T3 (da) * 1991-08-23 2006-04-18 Nps Pharma Inc Calciumreceptoraktive molekyler
US5688938A (en) * 1991-08-23 1997-11-18 The Brigham & Women's Hospital, Inc. Calcium receptor-active molecules
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5321036A (en) * 1993-02-10 1994-06-14 Bristol-Myers Squibb Company Thiazole and oxazole-based β3 adrenergic receptor agonists
US5962314A (en) * 1993-02-23 1999-10-05 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
AU709303B2 (en) 1994-10-21 1999-08-26 Nps Pharmaceuticals, Inc. Calcium receptor-active compounds
PT907631E (pt) 1996-05-01 2003-10-31 Nps Pharma Inc Compostos inorganicos activos como receptores de ioes
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL56308C (ro) * 1941-03-15
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
GB1301134A (en) 1970-07-18 1972-12-29 Pfizer Ltd SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES
BE788850A (fr) * 1972-09-15 1973-03-15 Hoffmann La Roche Derives d'acide benzoique
IE39247B1 (en) * 1973-05-07 1978-08-30 Allen & Hanburys Ltd Substituted benzamides
US4000192A (en) * 1973-05-07 1976-12-28 Allen & Hanburys Limited Pharmacologically active compounds
NZ190854A (en) * 1978-06-28 1984-10-19 Beecham Group Ltd 2-hydroxy-2-phenyl ethylamine derivatives;pharmaceutical compositions
CA1145766A (en) * 1978-07-03 1983-05-03 Jack Mills Optically active phenethanolamines and method for increasing cardiac contractility

Also Published As

Publication number Publication date
BE877394A (fr) 1980-01-02
CS209815B2 (en) 1981-12-31
IE48769B1 (en) 1985-05-15
SU1007554A3 (ru) 1983-03-23
EG14238A (en) 1983-12-31
PH15275A (en) 1982-11-02
FR2430411B1 (ro) 1983-08-19
PL117997B1 (en) 1981-09-30
EP0007204B1 (en) 1982-11-24
FI792081A (fi) 1980-01-04
DD144761A5 (de) 1980-11-05
CA1145767A (en) 1983-05-03
GB2101582B (en) 1983-06-08
RO77728A (ro) 1981-11-24
GB2028802B (en) 1983-03-30
NZ190863A (en) 1982-05-25
IL57671A (en) 1982-11-30
PL216811A1 (ro) 1980-08-25
DK268779A (da) 1980-01-04
AR231434A1 (es) 1984-11-30
ES490215A0 (es) 1981-04-16
AU523720B2 (en) 1982-08-12
AU523721B2 (en) 1982-08-12
PT69839A (en) 1979-07-01
SU957761A3 (ru) 1982-09-07
ZA793297B (en) 1981-02-25
AR229080A1 (es) 1983-06-15
FI792082A (fi) 1980-01-04
AU4848979A (en) 1980-01-10
FR2430410B1 (fr) 1986-03-21
ES482156A1 (es) 1980-08-16
ES490214A0 (es) 1981-04-16
BG31645A3 (en) 1982-02-15
EP0048037A1 (en) 1982-03-24
CS208663B2 (en) 1981-09-15
PL121297B1 (en) 1982-04-30
ATA463579A (de) 1983-04-15
BG31647A3 (en) 1982-02-15
LU81457A1 (fr) 1979-10-30
FR2430411A1 (fr) 1980-02-01
SU965350A3 (ru) 1982-10-07
GR74524B (ro) 1984-06-29
EP0006766A1 (en) 1980-01-09
LU81458A1 (fr) 1979-10-30
AR225744A1 (es) 1982-04-30
CS208662B2 (en) 1981-09-15
DE2964091D1 (en) 1982-12-30
ATA463679A (de) 1981-10-15
DK268679A (da) 1980-01-04
IL57671A0 (en) 1979-10-31
ES8104190A1 (es) 1981-04-16
KR880002310B1 (ko) 1988-10-22
RO77732A (ro) 1981-11-24
FR2430410A1 (fr) 1980-02-01
BE877393A (fr) 1980-01-02
BG31375A3 (en) 1981-12-15
DK160936B (da) 1991-05-06
JPS6254095B2 (ro) 1987-11-13
AT367025B (de) 1982-05-25
AT372937B (de) 1983-11-25
BG31646A3 (en) 1982-02-15
EP0007204A1 (en) 1980-01-23
DD144762A5 (de) 1980-11-05
RO83051B (ro) 1984-02-28
IE791228L (en) 1980-01-03
JPS559096A (en) 1980-01-22
AR227165A1 (es) 1982-09-30
RO83052A (ro) 1984-02-21
RO83051A (ro) 1984-02-21
AU4848779A (en) 1980-01-10
FR2450806B1 (fr) 1985-07-12
KR830001187A (ko) 1983-04-29
IL57672A (en) 1983-03-31
CS208664B2 (en) 1981-09-15
PL216814A1 (ro) 1980-03-24
DK160936C (da) 1991-10-21
IE791227L (en) 1980-01-03
PH14522A (en) 1981-08-26
FR2450806A1 (fr) 1980-10-03
GB2028802A (en) 1980-03-12
NZ190861A (en) 1981-12-15
HU179172B (en) 1982-08-28
PL117551B1 (en) 1981-08-31
HU179171B (en) 1982-08-28
CH643529A5 (fr) 1984-06-15
PT69843A (en) 1979-07-01
CA1142954A (en) 1983-03-15
SU849997A3 (ru) 1981-07-23
JPS559097A (en) 1980-01-22
CH642618A5 (fr) 1984-04-30
IL57672A0 (en) 1979-10-31
DE2964604D1 (en) 1983-03-03
ZA793296B (en) 1981-02-25
PL117996B1 (en) 1981-09-30
IE48586B1 (en) 1985-03-20
GB2028799A (en) 1980-03-12
ES482155A1 (es) 1980-08-16
GB2101582A (en) 1983-01-19
EP0006766B1 (en) 1983-01-26
ES8104189A1 (es) 1981-04-16
GR72940B (ro) 1984-01-16
GB2028799B (en) 1982-09-08

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