ES479440A1 - Un procedimiento para preparar compuestos con propiedades broncodilatadoras. - Google Patents
Un procedimiento para preparar compuestos con propiedades broncodilatadoras.Info
- Publication number
- ES479440A1 ES479440A1 ES479440A ES479440A ES479440A1 ES 479440 A1 ES479440 A1 ES 479440A1 ES 479440 A ES479440 A ES 479440A ES 479440 A ES479440 A ES 479440A ES 479440 A1 ES479440 A1 ES 479440A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- group
- carbon atoms
- hydrogen
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000002169 ethanolamines Chemical class 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 9
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 239000001257 hydrogen Substances 0.000 abstract 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
- 125000001931 aliphatic group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 4
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 125000004923 naphthylmethyl group Chemical group C1(=CC=CC2=CC=CC=C12)C* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/86—Ketones containing a keto group bound to a six-membered aromatic ring containing —CHO groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1403378 | 1978-04-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES479440A1 true ES479440A1 (es) | 1980-06-16 |
Family
ID=10033794
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES479440A Expired ES479440A1 (es) | 1978-04-10 | 1979-04-09 | Un procedimiento para preparar compuestos con propiedades broncodilatadoras. |
| ES486580A Expired ES486580A1 (es) | 1978-04-10 | 1979-12-04 | Un procedimiento para preparar compuestos con propiedades broncodilatadoras |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES486580A Expired ES486580A1 (es) | 1978-04-10 | 1979-12-04 | Un procedimiento para preparar compuestos con propiedades broncodilatadoras |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0004835B1 (OSRAM) |
| JP (1) | JPS54145624A (OSRAM) |
| AT (1) | AT367022B (OSRAM) |
| AU (1) | AU520787B2 (OSRAM) |
| BR (1) | BR7902193A (OSRAM) |
| CA (1) | CA1150296A (OSRAM) |
| CS (1) | CS228114B2 (OSRAM) |
| CY (1) | CY1228A (OSRAM) |
| DD (1) | DD142875A5 (OSRAM) |
| DE (1) | DE2960968D1 (OSRAM) |
| DK (1) | DK146779A (OSRAM) |
| ES (2) | ES479440A1 (OSRAM) |
| FI (1) | FI70405C (OSRAM) |
| GR (1) | GR66484B (OSRAM) |
| HK (1) | HK35184A (OSRAM) |
| HU (1) | HU178207B (OSRAM) |
| IE (1) | IE48569B1 (OSRAM) |
| MY (1) | MY8500403A (OSRAM) |
| NO (1) | NO147103C (OSRAM) |
| NZ (1) | NZ190078A (OSRAM) |
| PH (1) | PH17202A (OSRAM) |
| PT (1) | PT69459A (OSRAM) |
| SG (1) | SG6984G (OSRAM) |
| SU (2) | SU961557A3 (OSRAM) |
| ZA (1) | ZA791403B (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6010021B2 (ja) * | 1979-01-31 | 1985-03-14 | 田辺製薬株式会社 | 新規ベンジルアルコ−ル誘導体及びその製法 |
| JPS6241829Y2 (OSRAM) * | 1980-03-28 | 1987-10-26 | ||
| EP0052963B1 (en) * | 1980-11-20 | 1985-02-20 | Beecham Group Plc | Secondary amines |
| US4454337A (en) * | 1981-06-29 | 1984-06-12 | Smithkline Beckman Corporation | Semicarbazide intermediates for preparing 4-substituted indoles |
| CH653322A5 (de) * | 1982-12-01 | 1985-12-31 | Siegfried Ag | Verfahren zur herstellung von phenylethanolaminen. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL6610530A (OSRAM) * | 1966-07-27 | 1968-01-29 | ||
| DE1768167A1 (de) * | 1968-04-06 | 1971-08-05 | Troponwerke Dinklage & Co | 1-(3-Hydroxyphenyl)-2-[3-phenyl-2-methylpropyl-(2)-amino]-aethynol-(1) |
| DE2008654A1 (de) * | 1970-02-25 | 1971-09-09 | C H Boehnnger Sohn, 6507 Ingel heim | Ammoathanoldenvate |
| JPS52113934A (en) * | 1976-03-19 | 1977-09-24 | Eisai Co Ltd | Phenethylamine derivatives and bronchodilator containing the same |
-
1979
- 1979-03-23 ZA ZA791403A patent/ZA791403B/xx unknown
- 1979-03-27 CA CA000324248A patent/CA1150296A/en not_active Expired
- 1979-04-02 AU AU45688/79A patent/AU520787B2/en not_active Ceased
- 1979-04-02 NZ NZ190078A patent/NZ190078A/en unknown
- 1979-04-03 EP EP79850021A patent/EP0004835B1/en not_active Expired
- 1979-04-03 GR GR58773A patent/GR66484B/el unknown
- 1979-04-03 DE DE7979850021T patent/DE2960968D1/de not_active Expired
- 1979-04-03 CY CY1228A patent/CY1228A/xx unknown
- 1979-04-04 FI FI791118A patent/FI70405C/fi not_active IP Right Cessation
- 1979-04-09 PT PT69459A patent/PT69459A/pt unknown
- 1979-04-09 DK DK146779A patent/DK146779A/da not_active IP Right Cessation
- 1979-04-09 NO NO791199A patent/NO147103C/no unknown
- 1979-04-09 HU HU79DA363A patent/HU178207B/hu unknown
- 1979-04-09 CS CS792407A patent/CS228114B2/cs unknown
- 1979-04-09 BR BR7902193A patent/BR7902193A/pt unknown
- 1979-04-09 SU SU792746153A patent/SU961557A3/ru active
- 1979-04-09 ES ES479440A patent/ES479440A1/es not_active Expired
- 1979-04-10 DD DD79212113A patent/DD142875A5/de unknown
- 1979-04-10 AT AT0265579A patent/AT367022B/de not_active IP Right Cessation
- 1979-04-10 PH PH22374A patent/PH17202A/en unknown
- 1979-04-10 JP JP4337779A patent/JPS54145624A/ja active Granted
- 1979-08-08 IE IE754/79A patent/IE48569B1/en unknown
- 1979-12-04 ES ES486580A patent/ES486580A1/es not_active Expired
-
1981
- 1981-07-02 SU SU813308200A patent/SU1011046A3/ru active
-
1984
- 1984-01-25 SG SG69/84A patent/SG6984G/en unknown
- 1984-04-26 HK HK351/84A patent/HK35184A/xx unknown
-
1985
- 1985-12-30 MY MY403/85A patent/MY8500403A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SU1011046A3 (ru) | 1983-04-07 |
| AT367022B (de) | 1982-05-25 |
| DK146779A (da) | 1979-10-11 |
| IE48569B1 (en) | 1985-03-06 |
| IE790754L (en) | 1979-10-10 |
| DE2960968D1 (en) | 1981-12-24 |
| GR66484B (OSRAM) | 1981-03-24 |
| SU961557A3 (ru) | 1982-09-23 |
| JPS54145624A (en) | 1979-11-14 |
| NO147103B (no) | 1982-10-25 |
| AU4568879A (en) | 1980-10-09 |
| FI70405B (fi) | 1986-03-27 |
| EP0004835A1 (en) | 1979-10-17 |
| CS228114B2 (en) | 1984-05-14 |
| CY1228A (en) | 1984-06-29 |
| ZA791403B (en) | 1980-05-28 |
| AU520787B2 (en) | 1982-02-25 |
| MY8500403A (en) | 1985-12-31 |
| NO791199L (no) | 1979-10-11 |
| FI70405C (fi) | 1986-09-19 |
| NO147103C (no) | 1983-02-02 |
| FI791118A7 (fi) | 1979-10-11 |
| SG6984G (en) | 1984-08-03 |
| NZ190078A (en) | 1984-07-06 |
| EP0004835B1 (en) | 1981-10-14 |
| PT69459A (en) | 1979-05-01 |
| JPS638936B2 (OSRAM) | 1988-02-25 |
| PH17202A (en) | 1984-06-19 |
| ATA265579A (de) | 1981-10-15 |
| BR7902193A (pt) | 1979-12-04 |
| CA1150296A (en) | 1983-07-19 |
| HK35184A (en) | 1984-05-04 |
| HU178207B (en) | 1982-03-28 |
| ES486580A1 (es) | 1980-10-01 |
| DD142875A5 (de) | 1980-07-16 |
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