GB995864A - New derivatives of hydantoins - Google Patents

New derivatives of hydantoins

Info

Publication number
GB995864A
GB995864A GB5187/62A GB518762A GB995864A GB 995864 A GB995864 A GB 995864A GB 5187/62 A GB5187/62 A GB 5187/62A GB 518762 A GB518762 A GB 518762A GB 995864 A GB995864 A GB 995864A
Authority
GB
United Kingdom
Prior art keywords
hydrogen atom
hydantoins
compounds
new derivatives
cyclohexanespirohydantoin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5187/62A
Inventor
Colin Henry Cashin
William Oldfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Distillers Co Yeast Ltd
Distillers Co Ltd
Original Assignee
Distillers Co Yeast Ltd
Distillers Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Distillers Co Yeast Ltd, Distillers Co Ltd filed Critical Distillers Co Yeast Ltd
Priority to GB5187/62A priority Critical patent/GB995864A/en
Priority to CH120563A priority patent/CH421976A/en
Priority to FR933538A priority patent/FR2597M/en
Publication of GB995864A publication Critical patent/GB995864A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises compounds of formula <FORM:0995864/C2/1> where n is 1 or 2, R1 and R2 are hydrogen atoms alkyl groups having up to 8 carbon atoms, and R3 is a hydrogen atom or an acyl group, and their preparation by (a) reaction of cyclohexanespirohydantoin or an alkylcyclohexanespirohydantoin with formaldehyde, a 2-haloethanol, or a haloformic or haloacetic acid ester, or (b) by acylation of a product of (a) wherein R3 is a hydrogen atom. The compounds of the invention possess analgesic and/or anti-inflammatory properties, and may be used in combination with a pharmaceutical carrier in forms suitable for oral or parenteral administration, for example as tablets, capsules, solutions or suspensions.
GB5187/62A 1962-02-10 1962-02-10 New derivatives of hydantoins Expired GB995864A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB5187/62A GB995864A (en) 1962-02-10 1962-02-10 New derivatives of hydantoins
CH120563A CH421976A (en) 1962-02-10 1963-01-31 Process for the preparation of novel hydantoin derivatives
FR933538A FR2597M (en) 1962-02-10 1963-05-03 New hydantoines derivatives.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5187/62A GB995864A (en) 1962-02-10 1962-02-10 New derivatives of hydantoins

Publications (1)

Publication Number Publication Date
GB995864A true GB995864A (en) 1965-06-23

Family

ID=9791344

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5187/62A Expired GB995864A (en) 1962-02-10 1962-02-10 New derivatives of hydantoins

Country Status (3)

Country Link
CH (1) CH421976A (en)
FR (1) FR2597M (en)
GB (1) GB995864A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200758A (en) * 1979-03-19 1980-04-29 Zoecon Corporation 2,4-Imidazolidinedionylmethyl esters and thiolesters of anilino acids
WO2003073979A2 (en) * 2002-03-07 2003-09-12 Schwarz Pharma Ag Derivatives of azaspiro compounds for the treatment of pain

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200758A (en) * 1979-03-19 1980-04-29 Zoecon Corporation 2,4-Imidazolidinedionylmethyl esters and thiolesters of anilino acids
WO2003073979A2 (en) * 2002-03-07 2003-09-12 Schwarz Pharma Ag Derivatives of azaspiro compounds for the treatment of pain
WO2003073979A3 (en) * 2002-03-07 2003-12-31 Sanol Arznei Schwarz Gmbh Derivatives of azaspiro compounds for the treatment of pain
DE10210195B4 (en) * 2002-03-07 2005-12-15 Schwarz Pharma Ag Use of 1,3-diazaspiro [4,5] decane-2,4-dithione for the treatment of pain
US7282515B2 (en) 2002-03-07 2007-10-16 Schwarz Pharma Ag Derivatives of azaspiro compounds for the treatment of pain

Also Published As

Publication number Publication date
CH421976A (en) 1966-10-15
FR2597M (en) 1964-06-15

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