ATE6507T1 - Piperidinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents

Piperidinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE6507T1
ATE6507T1 AT80850106T AT80850106T ATE6507T1 AT E6507 T1 ATE6507 T1 AT E6507T1 AT 80850106 T AT80850106 T AT 80850106T AT 80850106 T AT80850106 T AT 80850106T AT E6507 T1 ATE6507 T1 AT E6507T1
Authority
AT
Austria
Prior art keywords
compositions containing
methyl
piperide
individuals
preparation
Prior art date
Application number
AT80850106T
Other languages
English (en)
Inventor
Bo Af Ekenstam
Gunnar Aberg
Original Assignee
Bo Af Ekenstam
Gunnar Aberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bo Af Ekenstam, Gunnar Aberg filed Critical Bo Af Ekenstam
Application granted granted Critical
Publication of ATE6507T1 publication Critical patent/ATE6507T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT80850106T 1979-07-10 1980-06-27 Piperidinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen. ATE6507T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE7906000A SE431092B (sv) 1979-07-10 1979-07-10 Terapeutiskt aktiva, substituerade piperidinkarboxianilider
EP80850106A EP0024382B1 (de) 1979-07-10 1980-06-27 Piperidinderivate, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE6507T1 true ATE6507T1 (de) 1984-03-15

Family

ID=20338488

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80850106T ATE6507T1 (de) 1979-07-10 1980-06-27 Piperidinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Country Status (19)

Country Link
US (1) US4302465A (de)
EP (1) EP0024382B1 (de)
JP (1) JPS5681561A (de)
AT (1) ATE6507T1 (de)
AU (1) AU538494B2 (de)
CA (1) CA1162924A (de)
CS (1) CS227011B2 (de)
DE (1) DE3066827D1 (de)
DK (1) DK290180A (de)
ES (1) ES8107185A1 (de)
FI (1) FI802173A (de)
GR (1) GR69077B (de)
HU (1) HU180156B (de)
IL (1) IL60390A (de)
NO (1) NO802062L (de)
NZ (1) NZ194284A (de)
PL (1) PL125596B1 (de)
SE (1) SE431092B (de)
ZA (1) ZA803827B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443450A (en) * 1982-04-15 1984-04-17 Research Corporation Platelet aggregation inhibitory agents and intermediates therefor
US4556664A (en) * 1984-03-13 1985-12-03 Gunnar A. K. Aberg Method and composition for the treatment of cardiac arrhythmias
US4695576A (en) * 1984-07-09 1987-09-22 Astra Lake Medel Aktiebolag L-N-n-propylpipecolic acid-2,6-xylidide
SE451840B (sv) * 1986-01-03 1987-11-02 Astra Laekemedel Ab Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning
US4859685A (en) * 1986-08-13 1989-08-22 Boc, Inc. Anesthetic composition and method of using the same
US5234957A (en) * 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5332576A (en) * 1991-02-27 1994-07-26 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
BR0002246A (pt) * 2000-04-06 2003-04-15 Cristalia Prod Quimicos Farm Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis
US6512120B1 (en) 2001-03-12 2003-01-28 Ortho Mcneil Pharmaceutical, Inc. Methods for the synthesis of densely functionalized pyrrolidine intermediates
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US7425292B2 (en) 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US7910641B2 (en) 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US8603514B2 (en) * 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8017150B2 (en) 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
JP2009523808A (ja) * 2006-01-20 2009-06-25 モノソル アールエックス リミテッド ライアビリティ カンパニー 活性物質の粘膜投与のためのフィルム包帯
CN101516331A (zh) 2006-09-20 2009-08-26 莫诺索尔克斯有限公司 含有抗泡沫调味剂的可食用水溶性膜
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
WO2011156711A1 (en) 2010-06-10 2011-12-15 Schobel Alexander M Nanoparticle film delivery systems
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
US20170296484A1 (en) 2015-11-23 2017-10-19 Grace Therapeutics Llc Topical Film-Forming Spray
BR112018072539A2 (pt) 2016-05-05 2019-03-26 Aquestive Therapeutics, Inc. composições de epinefrina de administração aumentada
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
MX2021007213A (es) 2018-12-19 2021-09-23 Grace therapeutics Inc Composicion terapeutica de lidocaina intranasal.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE191321C1 (de) 1964-01-01
SE191322C1 (de) 1964-01-01
SE164063C1 (de) 1958-07-22
US2792399A (en) * 1954-05-29 1957-05-14 Bofors Ab Anilides of heterocyclic compounds
US2799679A (en) * 1955-04-28 1957-07-16 Bofors Ab Process of preparing amides of heterocyclic carboxylic acids
GB889225A (de) * 1959-07-01
NL6803337A (de) 1967-03-20 1968-09-23
SE7607114L (sv) * 1976-06-22 1977-12-23 Bofors Ab Sett att framstella hydrokloriden av n-metylpiperidin-2-karbonsyra-2,6-xyllidid
GB1561023A (en) * 1977-04-22 1980-02-13 Beecham Group Ltd 2-methoxy - 5 - chloro aniline derivatives
US4146628A (en) * 1977-08-04 1979-03-27 Edna Oppenheimer Antiarrhythmic quinuclidine carboxylic acid xylidide and method of producing the same and similar compounds
DE2742582A1 (de) * 1977-09-22 1979-04-05 Hoechst Ag Substituierte piperidinhydroxyamide, ihre herstellung und verwendung als lichtschutzmittel

Also Published As

Publication number Publication date
DE3066827D1 (en) 1984-04-12
US4302465A (en) 1981-11-24
NO802062L (no) 1981-01-12
EP0024382B1 (de) 1984-03-07
FI802173A (fi) 1981-01-11
NZ194284A (en) 1983-06-14
PL125596B1 (en) 1983-05-31
ES493230A0 (es) 1981-08-16
SE431092B (sv) 1984-01-16
EP0024382A1 (de) 1981-03-04
JPS6135178B2 (de) 1986-08-12
ZA803827B (en) 1981-06-24
GR69077B (de) 1982-04-26
PL225542A1 (de) 1981-12-23
AU538494B2 (en) 1984-08-16
ES8107185A1 (es) 1981-08-16
AU6003280A (en) 1981-01-15
CA1162924A (en) 1984-02-28
IL60390A (en) 1984-10-31
US4302465B1 (de) 1984-01-24
CS227011B2 (en) 1984-04-16
SE7906000L (sv) 1981-01-20
JPS5681561A (en) 1981-07-03
HU180156B (en) 1983-02-28
DK290180A (da) 1981-01-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee