ES482083A1 - Un procedimiento para la preparacion de un derivado de teta-hidro-2h-benzo-c-pirrol. - Google Patents
Un procedimiento para la preparacion de un derivado de teta-hidro-2h-benzo-c-pirrol.Info
- Publication number
- ES482083A1 ES482083A1 ES482083A ES482083A ES482083A1 ES 482083 A1 ES482083 A1 ES 482083A1 ES 482083 A ES482083 A ES 482083A ES 482083 A ES482083 A ES 482083A ES 482083 A1 ES482083 A1 ES 482083A1
- Authority
- ES
- Spain
- Prior art keywords
- benzo
- tetrahydro
- therapeuticals
- pyrroles
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
Abstract
Un procedimiento para la preparación de un derivado de tetrahídro-2H-benzo(c)pirrol de fórmula general: **(Fórmula-01)** donde R1 es H o R2; Am es N (R2)2 y cada radical R2 es independientemente alilo, metilo, etilo o n-propilo; y sus sales de adición de ácidos farmacéuticamente aceptables; cuyo procedimiento se caracteriza por hacer reaccionar un compuesto de dl-5-amino- 4,5,6,7-terahidro-2H-benzo(c)pirrol de fórmula: **(Fórmula-02)** con un aldehido y después reducir con un hidruro metálico; o con un haluro de alquilo y después un haluro de acido, seguido de reducción con un hidruro metálico, para formar los compuestos de fórmula I donde R1 es H y Am es N(R2)2; seguido de reacción con un haluro de alquilo y una base para formar los compuestos de fórmula I donde R1 es R2 y Am es N(R2)2.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US506379A | 1979-01-22 | 1979-01-22 | |
| US06/020,560 US4235776A (en) | 1979-03-15 | 1979-03-15 | Tetrahydro-2H-benzo[c]pyrroles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES482083A1 true ES482083A1 (es) | 1980-04-01 |
Family
ID=26673874
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES482083A Expired ES482083A1 (es) | 1979-01-22 | 1979-06-29 | Un procedimiento para la preparacion de un derivado de teta-hidro-2h-benzo-c-pirrol. |
| ES490079A Granted ES490079A0 (es) | 1979-01-22 | 1980-03-28 | Un procedimiento para la preparacion de derivados de tetra- hidrobenzo c pirrol |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES490079A Granted ES490079A0 (es) | 1979-01-22 | 1980-03-28 | Un procedimiento para la preparacion de derivados de tetra- hidrobenzo c pirrol |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0014792B1 (es) |
| AR (1) | AR227134A1 (es) |
| AT (1) | AT360516B (es) |
| AU (1) | AU525367B2 (es) |
| BE (1) | BE877329A (es) |
| BG (2) | BG34762A3 (es) |
| CA (1) | CA1105473A (es) |
| CH (2) | CH643244A5 (es) |
| DD (2) | DD144666A5 (es) |
| DE (1) | DE2964139D1 (es) |
| DK (1) | DK155600C (es) |
| EG (1) | EG14069A (es) |
| ES (2) | ES482083A1 (es) |
| FI (1) | FI792045A (es) |
| FR (2) | FR2446817A1 (es) |
| GB (2) | GB2040914B (es) |
| GR (1) | GR72398B (es) |
| IE (1) | IE48648B1 (es) |
| IL (1) | IL57664A (es) |
| LU (1) | LU81438A1 (es) |
| NZ (1) | NZ190831A (es) |
| PH (1) | PH18288A (es) |
| PL (1) | PL122798B1 (es) |
| PT (1) | PT69826A (es) |
| RO (1) | RO77806A (es) |
| ZA (1) | ZA793242B (es) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1019111A (en) * | 1962-12-04 | 1966-02-02 | Arnzneimittelwerk Dresden Veb | Salts of 5-amino-isoindoline |
| BE634851A (es) * | 1963-05-15 | 1900-01-01 | ||
| FR3396M (fr) * | 1963-07-30 | 1965-06-28 | Dresden Arzneimittel | Dérivés n-acylés de la 5-amino-isoindoline et de leurs sels. |
-
1979
- 1979-06-26 DK DK268179A patent/DK155600C/da not_active IP Right Cessation
- 1979-06-26 CA CA330,566A patent/CA1105473A/en not_active Expired
- 1979-06-26 NZ NZ190831A patent/NZ190831A/en unknown
- 1979-06-26 IL IL57664A patent/IL57664A/xx unknown
- 1979-06-26 PT PT69826A patent/PT69826A/pt unknown
- 1979-06-27 FR FR7916573A patent/FR2446817A1/fr active Granted
- 1979-06-27 PH PH22696A patent/PH18288A/en unknown
- 1979-06-27 EG EG383/79A patent/EG14069A/xx active
- 1979-06-27 LU LU81438A patent/LU81438A1/xx unknown
- 1979-06-27 AU AU48442/79A patent/AU525367B2/en not_active Ceased
- 1979-06-27 RO RO7997974A patent/RO77806A/ro unknown
- 1979-06-28 AT AT452779A patent/AT360516B/de not_active IP Right Cessation
- 1979-06-28 FI FI792045A patent/FI792045A/fi not_active Application Discontinuation
- 1979-06-28 BE BE1/9438A patent/BE877329A/xx not_active IP Right Cessation
- 1979-06-28 BG BG7945095A patent/BG34762A3/xx unknown
- 1979-06-28 CH CH605779A patent/CH643244A5/fr not_active IP Right Cessation
- 1979-06-28 GB GB7922528A patent/GB2040914B/en not_active Expired
- 1979-06-28 BG BG7944129A patent/BG34761A3/xx unknown
- 1979-06-28 DE DE7979301248T patent/DE2964139D1/de not_active Expired
- 1979-06-28 GR GR59463A patent/GR72398B/el unknown
- 1979-06-28 EP EP79301248A patent/EP0014792B1/en not_active Expired
- 1979-06-29 DD DD79213988A patent/DD144666A5/de unknown
- 1979-06-29 ES ES482083A patent/ES482083A1/es not_active Expired
- 1979-06-29 AR AR277115A patent/AR227134A1/es active
- 1979-06-29 ZA ZA793242A patent/ZA793242B/xx unknown
- 1979-06-29 DD DD79220466A patent/DD150745A5/de unknown
- 1979-06-29 PL PL1979216718A patent/PL122798B1/pl unknown
- 1979-08-08 IE IE1208/79A patent/IE48648B1/en unknown
- 1979-11-06 FR FR7927313A patent/FR2446818A1/fr active Granted
-
1980
- 1980-03-28 ES ES490079A patent/ES490079A0/es active Granted
-
1982
- 1982-05-07 GB GB08213212A patent/GB2121029B/en not_active Expired
-
1983
- 1983-06-27 CH CH351683A patent/CH644595A5/fr not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970612 |