ES474575A1 - Procedimiento de producir (omega-aminoalcoxi)bibencilos far-maceuticamente activos - Google Patents
Procedimiento de producir (omega-aminoalcoxi)bibencilos far-maceuticamente activosInfo
- Publication number
- ES474575A1 ES474575A1 ES474575A ES474575A ES474575A1 ES 474575 A1 ES474575 A1 ES 474575A1 ES 474575 A ES474575 A ES 474575A ES 474575 A ES474575 A ES 474575A ES 474575 A1 ES474575 A1 ES 474575A1
- Authority
- ES
- Spain
- Prior art keywords
- bibenzyls
- aminoalkoxy
- omega
- substances
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/25—Web or sheet containing structurally defined element or component and including a second component containing structurally defined particles
- Y10T428/258—Alkali metal or alkaline earth metal or compound thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invención se refiere a la producción de (omega-aminoalcoxi) bibencilos que son farmacológicamente activos como inhibidores de la agregación de plaquetas. Más particularmente, esta invención se refiere a la preparación de 2-(omega- aminoalcoxi)bibencilos y de composiciones farmacéuticas que los contienen, eficaces para la inhibición de la agregación de plaquetas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52120710A JPS6021578B2 (ja) | 1977-10-07 | 1977-10-07 | (オメガ−アミノアルコキシ)ビベンジル類 |
JP8583378A JPS5513222A (en) | 1978-07-14 | 1978-07-14 | Aminoalkoxybibenzyl and its acid addition salt |
JP9404478A JPS5520740A (en) | 1978-08-01 | 1978-08-01 | Aminoalkoxybibenzyl and its acid addition salt |
Publications (1)
Publication Number | Publication Date |
---|---|
ES474575A1 true ES474575A1 (es) | 1980-01-16 |
Family
ID=27304972
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES474575A Expired ES474575A1 (es) | 1977-10-07 | 1978-10-06 | Procedimiento de producir (omega-aminoalcoxi)bibencilos far-maceuticamente activos |
ES480091A Expired ES480091A1 (es) | 1977-10-07 | 1979-04-30 | Metodo de producir (omega-aminoalcoxi) bibencilos farmaceu- ticamente activos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES480091A Expired ES480091A1 (es) | 1977-10-07 | 1979-04-30 | Metodo de producir (omega-aminoalcoxi) bibencilos farmaceu- ticamente activos. |
Country Status (13)
Country | Link |
---|---|
US (2) | US4220603A (es) |
EP (1) | EP0001759B1 (es) |
CA (1) | CA1105931A (es) |
CS (1) | CS209918B2 (es) |
DD (1) | DD139255A5 (es) |
DE (1) | DE2861477D1 (es) |
DK (1) | DK152040C (es) |
ES (2) | ES474575A1 (es) |
FI (1) | FI69840C (es) |
HU (1) | HU178306B (es) |
IT (1) | IT1099778B (es) |
NO (1) | NO146744C (es) |
SU (1) | SU786883A3 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5832847A (ja) * | 1981-08-20 | 1983-02-25 | Mitsubishi Chem Ind Ltd | (3−アミノプロポキシ)ビベンジル類 |
JPH02304022A (ja) * | 1989-05-18 | 1990-12-17 | Mitsubishi Kasei Corp | セロトニン拮抗剤 |
CA2110251A1 (en) * | 1992-11-30 | 1994-05-31 | Koichi Fujimoto | Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory diseases and psychosis |
US5843983A (en) | 1996-02-15 | 1998-12-01 | Sankyo Company, Limited | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use |
KR101653816B1 (ko) | 2014-06-25 | 2016-09-06 | 주식회사 대희화학 | 결정형 사포그릴레이트 옥살산염 일수화물 또는 이의 무수물 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3164607A (en) * | 1961-01-10 | 1965-01-05 | Upjohn Co | 2-phenyl-3-(tertiary amino alkoxy) phenyl-indenes |
US3077472A (en) * | 1961-03-21 | 1963-02-12 | Univ Kansas Res Foundation | 3-[4-(aminoalkoxy)-phenyl]-4-(4-oxyphenyl)-alkanes and alkenes |
GB945864A (en) * | 1961-08-18 | 1964-01-08 | Richardson Merrell Inc | Substituted triphenylethane |
GB1063744A (en) * | 1964-05-25 | 1967-03-30 | American Cyanamid Co | 4-substituted-4'-tertiary aminoalkoxy biphenyls |
US3476767A (en) * | 1965-10-11 | 1969-11-04 | Ciba Geigy Corp | 1,2-diaryl - 6 - tertiary amino lower-alkoxy-3,4-dihydro naphthalenes |
BE754405A (fr) * | 1969-08-05 | 1971-02-04 | Thomae Gmbh Dr K | Nouveaux beta-aryl-2-aminoalcoxystyrenes |
JPS598265B2 (ja) * | 1975-06-19 | 1984-02-23 | 三菱化学株式会社 | オメガ − アミノアルコキシビフエニルルイ マタハ ソノサンフカエンノセイゾウホウ |
FR2315913A1 (fr) * | 1975-06-19 | 1977-01-28 | Mitsubishi Chem Ind | 1-(omega-aminoalcoxy)-benzenes substitues en position 2 pharmaceutiquement actifs |
US4024282A (en) * | 1975-11-25 | 1977-05-17 | Mitsubishi Chemical Industries Ltd. | Pharmaceutically active 2-(3-alkylaminopropoxy)diphenylmethanes |
US4001216A (en) * | 1975-10-30 | 1977-01-04 | American Home Products Corporation | Aminoalkyl ethers of 2,2'- and 3,3'-dihydroxydesoxybenzoin |
-
1978
- 1978-09-19 US US05/943,621 patent/US4220603A/en not_active Expired - Lifetime
- 1978-09-22 CA CA311,866A patent/CA1105931A/en not_active Expired
- 1978-10-03 HU HU78MI636A patent/HU178306B/hu not_active IP Right Cessation
- 1978-10-04 DK DK441878A patent/DK152040C/da not_active IP Right Cessation
- 1978-10-05 DD DD78208291A patent/DD139255A5/xx not_active IP Right Cessation
- 1978-10-06 FI FI783049A patent/FI69840C/fi not_active IP Right Cessation
- 1978-10-06 NO NO78783399A patent/NO146744C/no unknown
- 1978-10-06 IT IT28531/78A patent/IT1099778B/it active
- 1978-10-06 DE DE7878101092T patent/DE2861477D1/de not_active Expired
- 1978-10-06 EP EP78101092A patent/EP0001759B1/en not_active Expired
- 1978-10-06 ES ES474575A patent/ES474575A1/es not_active Expired
- 1978-10-06 SU SU782668855A patent/SU786883A3/ru active
- 1978-10-09 CS CS786561A patent/CS209918B2/cs unknown
-
1979
- 1979-04-30 ES ES480091A patent/ES480091A1/es not_active Expired
- 1979-12-06 US US06/100,741 patent/US4323568A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE2861477D1 (en) | 1982-02-18 |
US4323568A (en) | 1982-04-06 |
NO783399L (no) | 1979-04-10 |
EP0001759B1 (en) | 1981-12-30 |
IT1099778B (it) | 1985-09-28 |
NO146744C (no) | 1982-12-01 |
FI69840C (fi) | 1986-05-26 |
US4220603A (en) | 1980-09-02 |
SU786883A3 (ru) | 1980-12-07 |
NO146744B (no) | 1982-08-23 |
DD139255A5 (de) | 1979-12-19 |
ES480091A1 (es) | 1980-04-01 |
FI69840B (fi) | 1985-12-31 |
CA1105931A (en) | 1981-07-28 |
DK152040C (da) | 1988-07-11 |
FI783049A (fi) | 1979-04-08 |
CS209918B2 (en) | 1981-12-31 |
HU178306B (en) | 1982-04-28 |
DK441878A (da) | 1979-04-08 |
EP0001759A1 (en) | 1979-05-16 |
DK152040B (da) | 1988-01-25 |
IT7828531A0 (it) | 1978-10-06 |
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