IT1099778B - (omega-amminolacossi) dibenzili farmaceuticamente attivi - Google Patents

(omega-amminolacossi) dibenzili farmaceuticamente attivi

Info

Publication number
IT1099778B
IT1099778B IT28531/78A IT2853178A IT1099778B IT 1099778 B IT1099778 B IT 1099778B IT 28531/78 A IT28531/78 A IT 28531/78A IT 2853178 A IT2853178 A IT 2853178A IT 1099778 B IT1099778 B IT 1099778B
Authority
IT
Italy
Prior art keywords
amminolacossi
omega
pharmaceutically active
active bonds
bonds
Prior art date
Application number
IT28531/78A
Other languages
English (en)
Other versions
IT7828531A0 (it
Original Assignee
Mitsubishi Chem Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52120710A external-priority patent/JPS6021578B2/ja
Priority claimed from JP8583378A external-priority patent/JPS5513222A/ja
Priority claimed from JP9404478A external-priority patent/JPS5520740A/ja
Application filed by Mitsubishi Chem Ind filed Critical Mitsubishi Chem Ind
Publication of IT7828531A0 publication Critical patent/IT7828531A0/it
Application granted granted Critical
Publication of IT1099778B publication Critical patent/IT1099778B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/25Web or sheet containing structurally defined element or component and including a second component containing structurally defined particles
    • Y10T428/258Alkali metal or alkaline earth metal or compound thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT28531/78A 1977-10-07 1978-10-06 (omega-amminolacossi) dibenzili farmaceuticamente attivi IT1099778B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP52120710A JPS6021578B2 (ja) 1977-10-07 1977-10-07 (オメガ−アミノアルコキシ)ビベンジル類
JP8583378A JPS5513222A (en) 1978-07-14 1978-07-14 Aminoalkoxybibenzyl and its acid addition salt
JP9404478A JPS5520740A (en) 1978-08-01 1978-08-01 Aminoalkoxybibenzyl and its acid addition salt

Publications (2)

Publication Number Publication Date
IT7828531A0 IT7828531A0 (it) 1978-10-06
IT1099778B true IT1099778B (it) 1985-09-28

Family

ID=27304972

Family Applications (1)

Application Number Title Priority Date Filing Date
IT28531/78A IT1099778B (it) 1977-10-07 1978-10-06 (omega-amminolacossi) dibenzili farmaceuticamente attivi

Country Status (13)

Country Link
US (2) US4220603A (it)
EP (1) EP0001759B1 (it)
CA (1) CA1105931A (it)
CS (1) CS209918B2 (it)
DD (1) DD139255A5 (it)
DE (1) DE2861477D1 (it)
DK (1) DK152040C (it)
ES (2) ES474575A1 (it)
FI (1) FI69840C (it)
HU (1) HU178306B (it)
IT (1) IT1099778B (it)
NO (1) NO146744C (it)
SU (1) SU786883A3 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5832847A (ja) * 1981-08-20 1983-02-25 Mitsubishi Chem Ind Ltd (3−アミノプロポキシ)ビベンジル類
JPH02304022A (ja) * 1989-05-18 1990-12-17 Mitsubishi Kasei Corp セロトニン拮抗剤
TW385302B (en) * 1992-11-30 2000-03-21 Sankyo Co Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory diseases and psychosis
US5843983A (en) * 1996-02-15 1998-12-01 Sankyo Company, Limited Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use
KR101653816B1 (ko) 2014-06-25 2016-09-06 주식회사 대희화학 결정형 사포그릴레이트 옥살산염 일수화물 또는 이의 무수물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3164607A (en) * 1961-01-10 1965-01-05 Upjohn Co 2-phenyl-3-(tertiary amino alkoxy) phenyl-indenes
US3077472A (en) * 1961-03-21 1963-02-12 Univ Kansas Res Foundation 3-[4-(aminoalkoxy)-phenyl]-4-(4-oxyphenyl)-alkanes and alkenes
GB945864A (en) * 1961-08-18 1964-01-08 Richardson Merrell Inc Substituted triphenylethane
GB1063744A (en) * 1964-05-25 1967-03-30 American Cyanamid Co 4-substituted-4'-tertiary aminoalkoxy biphenyls
US3476767A (en) * 1965-10-11 1969-11-04 Ciba Geigy Corp 1,2-diaryl - 6 - tertiary amino lower-alkoxy-3,4-dihydro naphthalenes
BE754405A (fr) * 1969-08-05 1971-02-04 Thomae Gmbh Dr K Nouveaux beta-aryl-2-aminoalcoxystyrenes
JPS598265B2 (ja) * 1975-06-19 1984-02-23 三菱化学株式会社 オメガ − アミノアルコキシビフエニルルイ マタハ ソノサンフカエンノセイゾウホウ
US4024282A (en) * 1975-11-25 1977-05-17 Mitsubishi Chemical Industries Ltd. Pharmaceutically active 2-(3-alkylaminopropoxy)diphenylmethanes
NL188944C (nl) * 1975-06-19 1992-11-16 Mitsubishi Chem Ind Werkwijze voor het bereiden van omega-aminoalkoxybenzeenderivaten alsmede werkwijze voor het bereiden van farmaceutische preparaten met toepassing daarvan, als werkzame verbinding.
US4001216A (en) * 1975-10-30 1977-01-04 American Home Products Corporation Aminoalkyl ethers of 2,2'- and 3,3'-dihydroxydesoxybenzoin

Also Published As

Publication number Publication date
SU786883A3 (ru) 1980-12-07
US4323568A (en) 1982-04-06
DK152040C (da) 1988-07-11
DD139255A5 (de) 1979-12-19
ES480091A1 (es) 1980-04-01
NO146744C (no) 1982-12-01
IT7828531A0 (it) 1978-10-06
NO146744B (no) 1982-08-23
ES474575A1 (es) 1980-01-16
CS209918B2 (en) 1981-12-31
DK152040B (da) 1988-01-25
DK441878A (da) 1979-04-08
CA1105931A (en) 1981-07-28
DE2861477D1 (en) 1982-02-18
EP0001759A1 (en) 1979-05-16
FI69840B (fi) 1985-12-31
NO783399L (no) 1979-04-10
FI69840C (fi) 1986-05-26
FI783049A (fi) 1979-04-08
HU178306B (en) 1982-04-28
EP0001759B1 (en) 1981-12-30
US4220603A (en) 1980-09-02

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19931027