FI65438B - Foerfarande foer framstaellning av farmakologiskt aktiva estrar av fosfonomyrsyra - Google Patents
Foerfarande foer framstaellning av farmakologiskt aktiva estrar av fosfonomyrsyraInfo
- Publication number
- FI65438B FI65438B FI783931A FI783931A FI65438B FI 65438 B FI65438 B FI 65438B FI 783931 A FI783931 A FI 783931A FI 783931 A FI783931 A FI 783931A FI 65438 B FI65438 B FI 65438B
- Authority
- FI
- Finland
- Prior art keywords
- phosphonomyrsyra
- pharmacologiskt
- estrar
- active
- foerfarande foer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3886—Acids containing the structure -C(=X)-P(=X)(XH)2 or NC-P(=X)(XH)2, (X = O, S, Se)
- C07F9/3891—Acids containing the structure -C(=X)-P(=X)(XH)2, (X = O, S, Se)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
- C07F9/4065—Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5358277 | 1977-12-22 | ||
GB5358377 | 1977-12-22 | ||
GB5358177 | 1977-12-22 | ||
GB5358077 | 1977-12-22 | ||
GB5358077 | 1977-12-22 | ||
GB5358377 | 1977-12-22 | ||
GB5358177 | 1977-12-22 | ||
GB5358277 | 1977-12-22 | ||
GB7828553 | 1978-07-03 | ||
GB7828548 | 1978-07-03 | ||
GB7828548 | 1978-07-03 | ||
GB7828553 | 1978-07-03 | ||
GB7828555 | 1978-07-03 | ||
GB7828552 | 1978-07-03 | ||
GB7828555 | 1978-07-03 | ||
GB7828552 | 1978-07-03 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI783931A FI783931A (fi) | 1979-06-23 |
FI65438B true FI65438B (fi) | 1984-01-31 |
FI65438C FI65438C (fi) | 1984-05-10 |
Family
ID=27571200
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI783931A FI65438C (fi) | 1977-12-22 | 1978-12-20 | Foerfarande foer framstaellning av farmakologiskt aktiva estrar av fosfonomyrsyra |
FI783932A FI68626C (fi) | 1977-12-22 | 1978-12-20 | Foerfarande foer framstaellning av nya terapeutiskt aktiva hydroxikarbonylfosfonsyraderivat |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI783932A FI68626C (fi) | 1977-12-22 | 1978-12-20 | Foerfarande foer framstaellning av nya terapeutiskt aktiva hydroxikarbonylfosfonsyraderivat |
Country Status (14)
Country | Link |
---|---|
US (4) | US4386081A (fi) |
EP (2) | EP0003275B1 (fi) |
JP (2) | JPS54109951A (fi) |
AT (1) | AT369017B (fi) |
AU (1) | AU530031B2 (fi) |
CA (2) | CA1140049A (fi) |
DE (2) | DE2861729D1 (fi) |
DK (2) | DK148632C (fi) |
FI (2) | FI65438C (fi) |
HK (1) | HK33584A (fi) |
IE (1) | IE48011B1 (fi) |
MY (1) | MY8500058A (fi) |
NO (2) | NO156611C (fi) |
SG (1) | SG82383G (fi) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1140049A (en) * | 1977-12-22 | 1983-01-25 | Dke J.E. Helgstran | Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid |
GB8501374D0 (en) * | 1985-01-18 | 1985-02-20 | Wellcome Found | Treatment of aids |
US4806532A (en) * | 1985-10-08 | 1989-02-21 | Mayo Foundation For Medical Education And Research | Inhibition of epithelial phosphate transport |
US6492352B1 (en) * | 1985-10-31 | 2002-12-10 | Astra Lakemedel Aktiebolag | Method for the control and treatment of acquired immunodeficiency syndrome (AIDS) |
US5166386A (en) * | 1989-09-18 | 1992-11-24 | E. R. Squibb & Sons, Inc. | Process of making isoprenoid phosphinylformic acid squalene synthetase inhibitors |
US5025003A (en) * | 1989-09-18 | 1991-06-18 | E. R. Squibb & Sons, Inc. | Isoprenoid phosphinylformic acid squalene synthetase inhibitors |
US5463092A (en) * | 1989-11-22 | 1995-10-31 | Vestar, Inc. | Lipid derivatives of phosphonacids for liposomal incorporation and method of use |
US5132414A (en) * | 1990-05-10 | 1992-07-21 | Dana-Farber Cancer Institute, Inc. | Dideoxynucleoside-5'-phosphonoformic acid compounds |
US5696277A (en) * | 1994-11-15 | 1997-12-09 | Karl Y. Hostetler | Antiviral prodrugs |
US7517858B1 (en) | 1995-06-07 | 2009-04-14 | The Regents Of The University Of California | Prodrugs of pharmaceuticals with improved bioavailability |
US6096730A (en) * | 1997-07-24 | 2000-08-01 | University Of Kentucky Research Foundation | Phosphonated agents and their antiangiogenic and antitumorigenic use |
WO1999008685A1 (en) * | 1997-08-18 | 1999-02-25 | Queen's University At Kingston | Phosphono-carboxylate compounds for treating amyloidosis |
US5869469A (en) * | 1997-08-18 | 1999-02-09 | Queen's University At Kingston | Phosphonocarboxylate compounds for treating amyloidosis |
US20040002079A1 (en) * | 1998-02-11 | 2004-01-01 | Gunn Robert B. | Sodium-phosphate cotransporter in lithium therapy for the treatment of mental illness |
EP1054664B1 (en) * | 1998-02-11 | 2012-08-08 | BHI Limited Partnership | Method for modulating macrophage activation |
US20020022657A1 (en) * | 1998-02-11 | 2002-02-21 | Francine Gervais | Methods for modulating neuronal cell death |
US6329356B1 (en) * | 1998-04-10 | 2001-12-11 | Neurochem, Inc. | Phosphono-carboxylate compounds for treating amyloidosis |
US6310073B1 (en) * | 1998-07-28 | 2001-10-30 | Queen's University At Kingston | Methods and compositions to treat glycosaminoglycan-associated molecular interactions |
DE60042896D1 (de) * | 1999-04-28 | 2009-10-15 | Bellus Health Int Ltd | Zusammensetzungen und verfahren zur behandlung von amyloidosis mit sulphonatderivaten |
US6562836B1 (en) | 1999-05-24 | 2003-05-13 | Queen's University Of Kingston | Methods and compounds for inhibiting amyloid deposits |
US6670399B2 (en) * | 1999-12-23 | 2003-12-30 | Neurochem (International) Limited | Compounds and methods for modulating cerebral amyloid angiopathy |
ES2268394T3 (es) * | 2002-04-01 | 2007-03-16 | Pfizer Inc. | Inhibidores de piranona y pirandiona de la arn polimerasa dependiente del arn del virus de la hepatitis c. |
DOP2003000641A (es) * | 2002-05-10 | 2003-11-15 | Pfizer | Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan |
US7148226B2 (en) * | 2003-02-21 | 2006-12-12 | Agouron Pharmaceuticals, Inc. | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same |
US20040214178A1 (en) * | 2003-04-24 | 2004-10-28 | Agouron Pharmaceuticals, Inc. | Reporter-selectable Hepatitis C virus replicon |
US7414076B2 (en) | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
US7244764B2 (en) | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
CN101538268B (zh) * | 2004-08-18 | 2011-07-27 | 辉瑞有限公司 | C型肝炎病毒rna依赖型rna聚合酶的抑制剂、以及使用该抑制剂的组合物和治疗剂 |
ITMI20041822A1 (it) * | 2004-09-24 | 2004-12-24 | Pharmaproducts Uk Ltd | "agente terapeutico utile per il trattamento di neoplasie plasmacellulari" |
US20060167057A1 (en) * | 2004-11-16 | 2006-07-27 | Xianqi Kong | Compounds for the treatment of CNS and amyloid associated diseases |
CA2900876A1 (en) | 2004-12-22 | 2006-08-17 | Bhi Limited Partnership | Methods and compositions for treating amyloid-related diseases |
MX2008008213A (es) * | 2005-12-22 | 2008-09-03 | Neurochem Int Ltd | Tratamiento de trastornos renales, nefropatia diabetica y dislipidemias. |
FI3851447T3 (fi) | 2006-10-12 | 2023-11-15 | Bellus Health Inc | Menetelmiä, yhdisteitä, koostumuksia ja vehikkeleitä 3-amino-1-propaanisulfonihapon vapauttamiseksi |
EP2120905A1 (en) * | 2006-12-22 | 2009-11-25 | BELLUS Health (International) Limited | Methods, compounds, and compositions for treating metabolic disorders and diabetes |
US20080293648A1 (en) * | 2007-01-05 | 2008-11-27 | Saha Pharmaceuticals, Inc. | Compositions and Methods for Cancer Treatment |
DE102012103717A1 (de) * | 2012-04-27 | 2013-11-14 | Westfälische Wilhelms-Universität Münster | Arzneimittel zur Behandlung von Tumorerkrankungen |
KR20160100964A (ko) * | 2013-12-19 | 2016-08-24 | 우베 고산 가부시키가이샤 | 비수 전해액, 그것을 이용한 축전 디바이스, 및 그것에 이용되는 포스포노폼산 화합물 |
ES2578902B1 (es) * | 2014-12-29 | 2017-07-07 | Agencia Pública Empresarial Sanitaria Costa Del Sol | Uso de análogos del ión pirofosfato para el tratamiento de la infección por VPH |
CN109400645A (zh) * | 2017-08-18 | 2019-03-01 | 四川海思科制药有限公司 | 一种磷酸衍生物及制备方法和用途 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3155597A (en) * | 1961-06-23 | 1964-11-03 | Monsanto Co | Extractive separation process |
US3997544A (en) * | 1968-05-24 | 1976-12-14 | E. I. Du Pont De Nemours And Company | Plant growth regulant carbamoylphosphonates |
US3846512A (en) * | 1968-05-24 | 1974-11-05 | Du Pont | Carbamoylphosphonates |
CH513590A (de) | 1968-05-24 | 1971-10-15 | Du Pont | Carbamoylphosphonat enthaltender Pflanzenwachstumsregler |
US3533995A (en) * | 1968-08-27 | 1970-10-13 | Fmc Corp | Heat stabilization of polyester resin with alkyl dialkoxyphosphinyl formate |
GB1317768A (en) | 1969-08-14 | 1973-05-23 | Du Pont | Plant growth regulants |
US3849102A (en) * | 1969-08-14 | 1974-11-19 | Du Pont | Plant growth regulant method |
US3767795A (en) * | 1971-02-25 | 1973-10-23 | Abbott Lab | Method for combating certain virus infection |
BR7405998D0 (pt) | 1973-07-23 | 1975-05-13 | Du Pont | Processos compostos e composicoes para controlar o crescimmento de plantas |
US3943201A (en) * | 1973-07-23 | 1976-03-09 | E. I. Du Pont De Nemours And Comapny | Alkoxy carboxycarbonylphosphonic acid esters |
US4017297A (en) * | 1975-08-29 | 1977-04-12 | E. I. Du Pont De Nemours And Company | Phosphonates for the control of bindweed |
US4092412A (en) * | 1976-04-30 | 1978-05-30 | Abbott Laboratories | Treatment of herpes simplex infections |
US4052439A (en) * | 1976-04-30 | 1977-10-04 | Abbott Laboratories | Carboxylic esters of phosphonoacetic acid |
CA1069526A (en) * | 1976-04-30 | 1980-01-08 | Thomas R. Herrin | Phosphorus esters of phosphonoacetic acid |
SE7607496L (sv) * | 1976-07-01 | 1978-01-02 | Astra Laekemedel Ab | Sett for bekempning av virusinfektioner |
CA1140049A (en) * | 1977-12-22 | 1983-01-25 | Dke J.E. Helgstran | Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid |
-
1978
- 1978-12-06 CA CA000317487A patent/CA1140049A/en not_active Expired
- 1978-12-06 CA CA000317520A patent/CA1144937A/en not_active Expired
- 1978-12-15 DK DK564278A patent/DK148632C/da not_active IP Right Cessation
- 1978-12-15 DK DK564178A patent/DK148631C/da not_active IP Right Cessation
- 1978-12-18 IE IE2493/78A patent/IE48011B1/en not_active IP Right Cessation
- 1978-12-19 AU AU42682/78A patent/AU530031B2/en not_active Expired
- 1978-12-19 EP EP78850027A patent/EP0003275B1/en not_active Expired
- 1978-12-19 DE DE7878850028T patent/DE2861729D1/de not_active Expired
- 1978-12-19 EP EP78850028A patent/EP0003007B1/en not_active Expired
- 1978-12-19 DE DE7878850027T patent/DE2861045D1/de not_active Expired
- 1978-12-20 FI FI783931A patent/FI65438C/fi not_active IP Right Cessation
- 1978-12-20 FI FI783932A patent/FI68626C/fi not_active IP Right Cessation
- 1978-12-21 NO NO784331A patent/NO156611C/no unknown
- 1978-12-21 NO NO784330A patent/NO154751C/no unknown
- 1978-12-22 JP JP15839878A patent/JPS54109951A/ja active Granted
- 1978-12-22 JP JP15839978A patent/JPS54106431A/ja active Granted
- 1978-12-22 AT AT0921778A patent/AT369017B/de not_active IP Right Cessation
-
1979
- 1979-11-13 US US06/093,167 patent/US4386081A/en not_active Expired - Lifetime
- 1979-11-13 US US06/093,166 patent/US4372894A/en not_active Expired - Lifetime
-
1982
- 1982-09-10 US US06/416,632 patent/US4536400A/en not_active Expired - Lifetime
- 1982-12-17 US US06/450,656 patent/US4591583A/en not_active Expired - Fee Related
-
1983
- 1983-12-23 SG SG823/83A patent/SG82383G/en unknown
-
1984
- 1984-04-18 HK HK335/84A patent/HK33584A/xx not_active IP Right Cessation
-
1985
- 1985-12-30 MY MY58/85A patent/MY8500058A/xx unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: ASTRA LAEKEMEDEL AKTIEBOLAG |