DK564278A - Fremgangsmaade til fremstilling af alifatiske fosforforbindelser - Google Patents

Fremgangsmaade til fremstilling af alifatiske fosforforbindelser

Info

Publication number
DK564278A
DK564278A DK564278A DK564278A DK564278A DK 564278 A DK564278 A DK 564278A DK 564278 A DK564278 A DK 564278A DK 564278 A DK564278 A DK 564278A DK 564278 A DK564278 A DK 564278A
Authority
DK
Denmark
Prior art keywords
alifatic
preparing
procedure
phosphorus compounds
phosphorus
Prior art date
Application number
DK564278A
Other languages
English (en)
Other versions
DK148632B (da
DK148632C (da
Inventor
Aa J E Helgstrand
K N G Johansson
A Misiorny
J O Noren
G B Stening
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of DK564278A publication Critical patent/DK564278A/da
Publication of DK148632B publication Critical patent/DK148632B/da
Application granted granted Critical
Publication of DK148632C publication Critical patent/DK148632C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3886—Acids containing the structure -C(=X)-P(=X)(XH)2 or NC-P(=X)(XH)2, (X = O, S, Se)
    • C07F9/3891—Acids containing the structure -C(=X)-P(=X)(XH)2, (X = O, S, Se)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
    • C07F9/4065—Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK564278A 1977-12-22 1978-12-15 Analogifremgangsmaade til fremstilling af hydroxykarbonylfosfonsyremonoestere eller optiske antipoder og/eller fysiologisk acceptable salte deraf DK148632C (da)

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
GB5358277 1977-12-22
GB5358377 1977-12-22
GB5358277 1977-12-22
GB5358077 1977-12-22
GB5358377 1977-12-22
GB5358177 1977-12-22
GB5358177 1977-12-22
GB5358077 1977-12-22
GB7828552 1978-07-03
GB7828548 1978-07-03
GB7828555 1978-07-03
GB7828548 1978-07-03
GB7828555 1978-07-03
GB7828553 1978-07-03
GB7828552 1978-07-03
GB7828553 1978-07-03

Publications (3)

Publication Number Publication Date
DK564278A true DK564278A (da) 1979-06-23
DK148632B DK148632B (da) 1985-08-19
DK148632C DK148632C (da) 1986-03-03

Family

ID=27571200

Family Applications (2)

Application Number Title Priority Date Filing Date
DK564178A DK148631C (da) 1977-12-22 1978-12-15 Analogifremgangsmaade til fremstilling af hydroxykarbonylfosfonsyremonoestere eller fysiologisk acceptable salte og/eller optiske isomerer deraf
DK564278A DK148632C (da) 1977-12-22 1978-12-15 Analogifremgangsmaade til fremstilling af hydroxykarbonylfosfonsyremonoestere eller optiske antipoder og/eller fysiologisk acceptable salte deraf

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK564178A DK148631C (da) 1977-12-22 1978-12-15 Analogifremgangsmaade til fremstilling af hydroxykarbonylfosfonsyremonoestere eller fysiologisk acceptable salte og/eller optiske isomerer deraf

Country Status (14)

Country Link
US (4) US4372894A (da)
EP (2) EP0003275B1 (da)
JP (2) JPS54109951A (da)
AT (1) AT369017B (da)
AU (1) AU530031B2 (da)
CA (2) CA1144937A (da)
DE (2) DE2861729D1 (da)
DK (2) DK148631C (da)
FI (2) FI65438C (da)
HK (1) HK33584A (da)
IE (1) IE48011B1 (da)
MY (1) MY8500058A (da)
NO (2) NO156611C (da)
SG (1) SG82383G (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1144937A (en) * 1977-12-22 1983-04-19 Dke J.E. Helgstrand Aromatic derivatives, pharmaceutical compositions and methods for combatting virus infections
GB8501374D0 (en) * 1985-01-18 1985-02-20 Wellcome Found Treatment of aids
US4806532A (en) * 1985-10-08 1989-02-21 Mayo Foundation For Medical Education And Research Inhibition of epithelial phosphate transport
US6492352B1 (en) * 1985-10-31 2002-12-10 Astra Lakemedel Aktiebolag Method for the control and treatment of acquired immunodeficiency syndrome (AIDS)
US5166386A (en) * 1989-09-18 1992-11-24 E. R. Squibb & Sons, Inc. Process of making isoprenoid phosphinylformic acid squalene synthetase inhibitors
US5025003A (en) * 1989-09-18 1991-06-18 E. R. Squibb & Sons, Inc. Isoprenoid phosphinylformic acid squalene synthetase inhibitors
US5463092A (en) * 1989-11-22 1995-10-31 Vestar, Inc. Lipid derivatives of phosphonacids for liposomal incorporation and method of use
US5132414A (en) * 1990-05-10 1992-07-21 Dana-Farber Cancer Institute, Inc. Dideoxynucleoside-5'-phosphonoformic acid compounds
US5696277A (en) * 1994-11-15 1997-12-09 Karl Y. Hostetler Antiviral prodrugs
US7517858B1 (en) 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
US6096730A (en) * 1997-07-24 2000-08-01 University Of Kentucky Research Foundation Phosphonated agents and their antiangiogenic and antitumorigenic use
US5869469A (en) * 1997-08-18 1999-02-09 Queen's University At Kingston Phosphonocarboxylate compounds for treating amyloidosis
NZ550116A (en) * 1997-08-18 2008-03-28 Neurochem Int Ltd Phosphono-carboxylate compounds for treating amyloidosis
CA2320224C (en) * 1998-02-11 2008-08-12 Neurochem, Inc. Method for modulating macrophage activation
US20040002079A1 (en) * 1998-02-11 2004-01-01 Gunn Robert B. Sodium-phosphate cotransporter in lithium therapy for the treatment of mental illness
US20020022657A1 (en) * 1998-02-11 2002-02-21 Francine Gervais Methods for modulating neuronal cell death
US6329356B1 (en) * 1998-04-10 2001-12-11 Neurochem, Inc. Phosphono-carboxylate compounds for treating amyloidosis
US6310073B1 (en) 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
DE60042896D1 (de) * 1999-04-28 2009-10-15 Bellus Health Int Ltd Zusammensetzungen und verfahren zur behandlung von amyloidosis mit sulphonatderivaten
US6562836B1 (en) 1999-05-24 2003-05-13 Queen's University Of Kingston Methods and compounds for inhibiting amyloid deposits
KR20090016517A (ko) * 1999-12-23 2009-02-13 벨루스 헬스 (인터내셔널) 리미티드 대뇌 아밀로이드 혈관병증을 조절하는 화합물 및 방법
MXPA04009672A (es) * 2002-04-01 2004-11-12 Pfizer Inhibidores de la rna polimerasa dependiente del rna del virus de la hepatitis c, y las composiciones y los tratamientos que usan los mismos.
DOP2003000641A (es) * 2002-05-10 2003-11-15 Pfizer Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan
US7148226B2 (en) * 2003-02-21 2006-12-12 Agouron Pharmaceuticals, Inc. Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
US20040214178A1 (en) * 2003-04-24 2004-10-28 Agouron Pharmaceuticals, Inc. Reporter-selectable Hepatitis C virus replicon
US20070010573A1 (en) 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7414076B2 (en) 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US7244764B2 (en) 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
RS51794B (en) * 2004-08-18 2011-12-31 Pfizer Inc. RNA SUBSTITUTE RNA POLYMERASE INHIBITORS OF HEPATITIS C VIRUS AND COMPOSITIONS AND TREATMENTS USING THEM
ITMI20041822A1 (it) * 2004-09-24 2004-12-24 Pharmaproducts Uk Ltd "agente terapeutico utile per il trattamento di neoplasie plasmacellulari"
US20060167057A1 (en) * 2004-11-16 2006-07-27 Xianqi Kong Compounds for the treatment of CNS and amyloid associated diseases
CA2592320C (en) 2004-12-22 2015-11-24 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
ES2352801T3 (es) * 2005-12-22 2011-02-23 Kiacta Sàrl Tratamiento de nefropatía diabética.
CA2666246C (en) 2006-10-12 2013-12-31 Bellus Health (International) Limited Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid
MX2009006768A (es) * 2006-12-22 2009-08-31 Bellus Health Int Ltd Metodos, compuestos, y composiciones para tratar trastornos metabolicos y diabetes.
US20080293648A1 (en) * 2007-01-05 2008-11-27 Saha Pharmaceuticals, Inc. Compositions and Methods for Cancer Treatment
DE102012103717A1 (de) * 2012-04-27 2013-11-14 Westfälische Wilhelms-Universität Münster Arzneimittel zur Behandlung von Tumorerkrankungen
JP6414077B2 (ja) * 2013-12-19 2018-10-31 宇部興産株式会社 非水電解液、それを用いた蓄電デバイス、及びそれに用いられるホスホノぎ酸化合物
ES2578902B1 (es) * 2014-12-29 2017-07-07 Agencia Pública Empresarial Sanitaria Costa Del Sol Uso de análogos del ión pirofosfato para el tratamiento de la infección por VPH
CN109400645A (zh) * 2017-08-18 2019-03-01 四川海思科制药有限公司 一种磷酸衍生物及制备方法和用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155597A (en) * 1961-06-23 1964-11-03 Monsanto Co Extractive separation process
CH513590A (de) 1968-05-24 1971-10-15 Du Pont Carbamoylphosphonat enthaltender Pflanzenwachstumsregler
US3997544A (en) * 1968-05-24 1976-12-14 E. I. Du Pont De Nemours And Company Plant growth regulant carbamoylphosphonates
US3846512A (en) * 1968-05-24 1974-11-05 Du Pont Carbamoylphosphonates
US3533995A (en) * 1968-08-27 1970-10-13 Fmc Corp Heat stabilization of polyester resin with alkyl dialkoxyphosphinyl formate
US3849102A (en) * 1969-08-14 1974-11-19 Du Pont Plant growth regulant method
GB1317768A (en) 1969-08-14 1973-05-23 Du Pont Plant growth regulants
US3767795A (en) * 1971-02-25 1973-10-23 Abbott Lab Method for combating certain virus infection
US3943201A (en) * 1973-07-23 1976-03-09 E. I. Du Pont De Nemours And Comapny Alkoxy carboxycarbonylphosphonic acid esters
BR7405998D0 (pt) * 1973-07-23 1975-05-13 Du Pont Processos compostos e composicoes para controlar o crescimmento de plantas
US4017297A (en) * 1975-08-29 1977-04-12 E. I. Du Pont De Nemours And Company Phosphonates for the control of bindweed
US4092412A (en) * 1976-04-30 1978-05-30 Abbott Laboratories Treatment of herpes simplex infections
US4052439A (en) * 1976-04-30 1977-10-04 Abbott Laboratories Carboxylic esters of phosphonoacetic acid
CA1069526A (en) * 1976-04-30 1980-01-08 Thomas R. Herrin Phosphorus esters of phosphonoacetic acid
SE7607496L (sv) * 1976-07-01 1978-01-02 Astra Laekemedel Ab Sett for bekempning av virusinfektioner
CA1144937A (en) * 1977-12-22 1983-04-19 Dke J.E. Helgstrand Aromatic derivatives, pharmaceutical compositions and methods for combatting virus infections

Also Published As

Publication number Publication date
EP0003007A3 (en) 1979-08-08
JPS6330885B2 (da) 1988-06-21
DK148631C (da) 1986-03-03
CA1140049A (en) 1983-01-25
AU4268278A (en) 1979-06-28
DK148632B (da) 1985-08-19
ATA921778A (de) 1982-04-15
EP0003007B1 (en) 1982-04-07
SG82383G (en) 1985-03-08
EP0003007A2 (en) 1979-07-11
NO154751B (no) 1986-09-08
DE2861729D1 (en) 1982-05-19
NO154751C (no) 1986-12-17
NO156611C (no) 1987-10-21
FI68626C (fi) 1985-10-10
MY8500058A (en) 1985-12-31
US4591583A (en) 1986-05-27
JPS6254118B2 (da) 1987-11-13
JPS54106431A (en) 1979-08-21
CA1144937A (en) 1983-04-19
EP0003275B1 (en) 1981-09-02
AU530031B2 (en) 1983-06-30
US4536400A (en) 1985-08-20
US4386081A (en) 1983-05-31
NO784330L (no) 1979-06-25
IE48011B1 (en) 1984-09-05
NO784331L (no) 1979-06-25
NO156611B (no) 1987-07-13
FI783932A (fi) 1979-06-23
DK564178A (da) 1979-06-23
HK33584A (en) 1984-04-27
DK148631B (da) 1985-08-19
FI65438C (fi) 1984-05-10
DK148632C (da) 1986-03-03
DE2861045D1 (en) 1981-11-26
FI783931A (fi) 1979-06-23
AT369017B (de) 1982-11-25
JPS54109951A (en) 1979-08-29
FI65438B (fi) 1984-01-31
US4372894A (en) 1983-02-08
IE782493L (en) 1979-06-22
EP0003275A1 (en) 1979-08-08
FI68626B (fi) 1985-06-28

Similar Documents

Publication Publication Date Title
DK564278A (da) Fremgangsmaade til fremstilling af alifatiske fosforforbindelser
DK195378A (da) Fremgangsmaade til fremstilling af polyenforbindelser
DK155733C (da) Fremgangsmaade til fremstilling af 4-hydroxy-2-oxo-pyrrolidinderivater
DK349478A (da) Fremgangsmaade til fremstilling af oligoimider
DK539578A (da) Fremgangsmaade til fremstilling af pleuromutilinglycsid-derivater
DK155279C (da) Fremgangsmaade til fremstilling af 4-hydroxy-2-oxo-pyrrolidinderivater
DK531178A (da) Fremgangsmaade til fremstilling af phenylglycinderivater
DK265978A (da) Fremgangsmaade til fremstilling af substituerede guanidiner
DK470978A (da) R fremgangsmaade til fremstilling af pyrazinobenzoxapinderivate
DK427878A (da) Fremgangsmaade til fremstilling af hidtil ukendte thiopropionamider
DK151078A (da) Fremgangsmaade til fremstilling af cyclobutanoner
DK169378A (da) Fremgangsmaade til fremstilling af en oploesning
DK152130C (da) Fremgangsmaade til fremstilling af benzooebaathienopyridinderivater
DK494978A (da) Fremgangsmaade til fremstilling af 2-iminoimidazolidinderivater
DK439878A (da) Fremgangsmaade til fremstilling af laktamforbindelser
DK262678A (da) Fremgangsmaade til fremstilling af quinolinonderivater
DK97578A (da) Fremgangsmaade til fremstilling af benzylpyrimidin-forbindelser
DK326778A (da) Fremgangsmaade til fremstilling af 7 alfamethoxycephalosporin-forbindelser
DK247877A (da) Fremgangsmade til fremstilling af klavamforbindelser
DK31478A (da) Fremgangsmaade til fremstilling af aralkylaniliner
DK512878A (da) Fremgangsmaade til fremstilling af blokerede polyisocyanter
DK385478A (da) Fremgangsmaade til fremstilling af dibenzocycloocteniminer
DK164878A (da) Fremgangsmaade til fremstilling af monochlorpinakolin
DK520178A (da) Fremgangsmaade til fremstilling af phenoxyalkanolamin-derivater
DK878A (da) Fremgangsmaade til fremstilling af chromonderivater

Legal Events

Date Code Title Description
PUP Patent expired