NO784331L - Aromatiske derivater, farmasoeytiske preparater og fremgangsmaate til bekjempelse av virusinfeksjoner - Google Patents

Aromatiske derivater, farmasoeytiske preparater og fremgangsmaate til bekjempelse av virusinfeksjoner

Info

Publication number
NO784331L
NO784331L NO784331A NO784331A NO784331L NO 784331 L NO784331 L NO 784331L NO 784331 A NO784331 A NO 784331A NO 784331 A NO784331 A NO 784331A NO 784331 L NO784331 L NO 784331L
Authority
NO
Norway
Prior art keywords
pharmaceuticals
procedures
virus infections
aromatic derivatives
fighting
Prior art date
Application number
NO784331A
Other languages
English (en)
Other versions
NO156611C (no
NO156611B (no
Inventor
Aake J E Helgstrand
Karl Nils-Gunnar Johansson
Alfons Misiorny
Jan-Olof Noren
Goeran Bertil Stening
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of NO784331L publication Critical patent/NO784331L/no
Publication of NO156611B publication Critical patent/NO156611B/no
Publication of NO156611C publication Critical patent/NO156611C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3886—Acids containing the structure -C(=X)-P(=X)(XH)2 or NC-P(=X)(XH)2, (X = O, S, Se)
    • C07F9/3891—Acids containing the structure -C(=X)-P(=X)(XH)2, (X = O, S, Se)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
    • C07F9/4065—Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO784331A 1977-12-22 1978-12-21 Analogifremgangsmaate for fremstilling av terapeutiske virksomme derivater av hydroksykarbonylfosfonsyre. NO156611C (no)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB5358177 1977-12-22
GB5358377 1977-12-22
GB5358277 1977-12-22
GB5358077 1977-12-22
GB7828553 1978-07-03
GB7828548 1978-07-03
GB7828552 1978-07-03
GB7828555 1978-07-03

Publications (3)

Publication Number Publication Date
NO784331L true NO784331L (no) 1979-06-25
NO156611B NO156611B (no) 1987-07-13
NO156611C NO156611C (no) 1987-10-21

Family

ID=27571200

Family Applications (2)

Application Number Title Priority Date Filing Date
NO784331A NO156611C (no) 1977-12-22 1978-12-21 Analogifremgangsmaate for fremstilling av terapeutiske virksomme derivater av hydroksykarbonylfosfonsyre.
NO784330A NO154751C (no) 1977-12-22 1978-12-21 Analogifremgangsmaate for fremstilling av terapeutisk virksomme hydroksykarbonylfosfonsyreestere.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO784330A NO154751C (no) 1977-12-22 1978-12-21 Analogifremgangsmaate for fremstilling av terapeutisk virksomme hydroksykarbonylfosfonsyreestere.

Country Status (14)

Country Link
US (4) US4386081A (no)
EP (2) EP0003275B1 (no)
JP (2) JPS54109951A (no)
AT (1) AT369017B (no)
AU (1) AU530031B2 (no)
CA (2) CA1140049A (no)
DE (2) DE2861729D1 (no)
DK (2) DK148631C (no)
FI (2) FI68626C (no)
HK (1) HK33584A (no)
IE (1) IE48011B1 (no)
MY (1) MY8500058A (no)
NO (2) NO156611C (no)
SG (1) SG82383G (no)

Families Citing this family (41)

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CA1140049A (en) * 1977-12-22 1983-01-25 Dke J.E. Helgstran Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid
GB8501374D0 (en) * 1985-01-18 1985-02-20 Wellcome Found Treatment of aids
US4806532A (en) * 1985-10-08 1989-02-21 Mayo Foundation For Medical Education And Research Inhibition of epithelial phosphate transport
US6492352B1 (en) * 1985-10-31 2002-12-10 Astra Lakemedel Aktiebolag Method for the control and treatment of acquired immunodeficiency syndrome (AIDS)
US5166386A (en) * 1989-09-18 1992-11-24 E. R. Squibb & Sons, Inc. Process of making isoprenoid phosphinylformic acid squalene synthetase inhibitors
US5025003A (en) * 1989-09-18 1991-06-18 E. R. Squibb & Sons, Inc. Isoprenoid phosphinylformic acid squalene synthetase inhibitors
US5463092A (en) * 1989-11-22 1995-10-31 Vestar, Inc. Lipid derivatives of phosphonacids for liposomal incorporation and method of use
US5132414A (en) * 1990-05-10 1992-07-21 Dana-Farber Cancer Institute, Inc. Dideoxynucleoside-5'-phosphonoformic acid compounds
US5696277A (en) * 1994-11-15 1997-12-09 Karl Y. Hostetler Antiviral prodrugs
US7517858B1 (en) 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
US6096730A (en) * 1997-07-24 2000-08-01 University Of Kentucky Research Foundation Phosphonated agents and their antiangiogenic and antitumorigenic use
NZ550116A (en) * 1997-08-18 2008-03-28 Neurochem Int Ltd Phosphono-carboxylate compounds for treating amyloidosis
US5869469A (en) * 1997-08-18 1999-02-09 Queen's University At Kingston Phosphonocarboxylate compounds for treating amyloidosis
US20020022657A1 (en) * 1998-02-11 2002-02-21 Francine Gervais Methods for modulating neuronal cell death
US20040002079A1 (en) * 1998-02-11 2004-01-01 Gunn Robert B. Sodium-phosphate cotransporter in lithium therapy for the treatment of mental illness
CA2632106A1 (en) * 1998-02-11 1999-08-19 Neurochem (International) Limited Method for modulating macrophage activation
US6329356B1 (en) * 1998-04-10 2001-12-11 Neurochem, Inc. Phosphono-carboxylate compounds for treating amyloidosis
US6310073B1 (en) 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
MXPA01010835A (es) * 1999-04-28 2003-07-14 Univ Kingston Composiciones y metodos para tratar amiloidosis.
US6562836B1 (en) 1999-05-24 2003-05-13 Queen's University Of Kingston Methods and compounds for inhibiting amyloid deposits
WO2001085093A2 (en) 1999-12-23 2001-11-15 Neurochem, Inc. Compounds and methods for modulating cerebral amyloid angiopathy
BR0308856A (pt) * 2002-04-01 2005-02-22 Pfizer Piranon e pirandion inibidores do rna polimerase dependente do rna do vìrus da hepatite c
DOP2003000641A (es) * 2002-05-10 2003-11-15 Pfizer Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan
US7148226B2 (en) * 2003-02-21 2006-12-12 Agouron Pharmaceuticals, Inc. Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
US20040214178A1 (en) * 2003-04-24 2004-10-28 Agouron Pharmaceuticals, Inc. Reporter-selectable Hepatitis C virus replicon
US7244764B2 (en) 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US20070010573A1 (en) 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7414076B2 (en) 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
UA88909C2 (ru) * 2004-08-18 2009-12-10 Пфайзер Инк. Ингибиторы рнк-зависимой рнк-полимеразы вируса гепатита с, фармацевтическая композиция на их основе и их применение
ITMI20041822A1 (it) * 2004-09-24 2004-12-24 Pharmaproducts Uk Ltd "agente terapeutico utile per il trattamento di neoplasie plasmacellulari"
EP1817305A2 (en) * 2004-11-16 2007-08-15 Neurochem (International) Limited Compounds for the treatment of cns and amyloid associated diseases
CA2592320C (en) 2004-12-22 2015-11-24 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
EP1968561B8 (en) * 2005-12-22 2010-10-20 Kiacta Sàrl Treatment of diabetic nephropathy
ES2533463T3 (es) 2006-10-12 2015-04-10 Bhi Limited Partnership Métodos, compuestos, composiciones y vehículos para suministrar ácido 3-amino-1-propanosulfónico
US20080262088A1 (en) * 2006-12-22 2008-10-23 Wendy Hauck Methods, compounds, and compositions for treating metabolic disorders and diabetes
US20080293648A1 (en) * 2007-01-05 2008-11-27 Saha Pharmaceuticals, Inc. Compositions and Methods for Cancer Treatment
DE102012103717A1 (de) * 2012-04-27 2013-11-14 Westfälische Wilhelms-Universität Münster Arzneimittel zur Behandlung von Tumorerkrankungen
KR20160100964A (ko) * 2013-12-19 2016-08-24 우베 고산 가부시키가이샤 비수 전해액, 그것을 이용한 축전 디바이스, 및 그것에 이용되는 포스포노폼산 화합물
ES2578902B1 (es) * 2014-12-29 2017-07-07 Agencia Pública Empresarial Sanitaria Costa Del Sol Uso de análogos del ión pirofosfato para el tratamiento de la infección por VPH
CN109400645A (zh) * 2017-08-18 2019-03-01 四川海思科制药有限公司 一种磷酸衍生物及制备方法和用途
WO2025106974A1 (en) * 2023-11-17 2025-05-22 The Board Of Trustees Of The Leland Stanford Junior University Prodrug moieties and compounds comprising the same

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155597A (en) * 1961-06-23 1964-11-03 Monsanto Co Extractive separation process
US3997544A (en) * 1968-05-24 1976-12-14 E. I. Du Pont De Nemours And Company Plant growth regulant carbamoylphosphonates
CH513590A (de) 1968-05-24 1971-10-15 Du Pont Carbamoylphosphonat enthaltender Pflanzenwachstumsregler
US3846512A (en) * 1968-05-24 1974-11-05 Du Pont Carbamoylphosphonates
US3533995A (en) * 1968-08-27 1970-10-13 Fmc Corp Heat stabilization of polyester resin with alkyl dialkoxyphosphinyl formate
GB1317768A (en) 1969-08-14 1973-05-23 Du Pont Plant growth regulants
US3849102A (en) * 1969-08-14 1974-11-19 Du Pont Plant growth regulant method
US3767795A (en) * 1971-02-25 1973-10-23 Abbott Lab Method for combating certain virus infection
US3943201A (en) * 1973-07-23 1976-03-09 E. I. Du Pont De Nemours And Comapny Alkoxy carboxycarbonylphosphonic acid esters
HU171255B (hu) * 1973-07-23 1977-12-28 Du Pont Kompozicii dlja regulirovki rosta rastenijj
US4017297A (en) * 1975-08-29 1977-04-12 E. I. Du Pont De Nemours And Company Phosphonates for the control of bindweed
CA1069526A (en) * 1976-04-30 1980-01-08 Thomas R. Herrin Phosphorus esters of phosphonoacetic acid
US4052439A (en) * 1976-04-30 1977-10-04 Abbott Laboratories Carboxylic esters of phosphonoacetic acid
US4092412A (en) * 1976-04-30 1978-05-30 Abbott Laboratories Treatment of herpes simplex infections
SE7607496L (sv) * 1976-07-01 1978-01-02 Astra Laekemedel Ab Sett for bekempning av virusinfektioner
CA1140049A (en) * 1977-12-22 1983-01-25 Dke J.E. Helgstran Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid

Also Published As

Publication number Publication date
DE2861729D1 (en) 1982-05-19
CA1144937A (en) 1983-04-19
DE2861045D1 (en) 1981-11-26
HK33584A (en) 1984-04-27
DK564278A (da) 1979-06-23
NO156611C (no) 1987-10-21
JPS6330885B2 (no) 1988-06-21
DK148631C (da) 1986-03-03
FI65438C (fi) 1984-05-10
FI783932A7 (fi) 1979-06-23
JPS54106431A (en) 1979-08-21
AU530031B2 (en) 1983-06-30
EP0003275B1 (en) 1981-09-02
EP0003007B1 (en) 1982-04-07
EP0003007A2 (en) 1979-07-11
AT369017B (de) 1982-11-25
IE48011B1 (en) 1984-09-05
FI65438B (fi) 1984-01-31
EP0003007A3 (en) 1979-08-08
NO154751C (no) 1986-12-17
NO156611B (no) 1987-07-13
FI783931A7 (fi) 1979-06-23
US4536400A (en) 1985-08-20
FI68626C (fi) 1985-10-10
MY8500058A (en) 1985-12-31
EP0003275A1 (en) 1979-08-08
IE782493L (en) 1979-06-22
ATA921778A (de) 1982-04-15
FI68626B (fi) 1985-06-28
DK148631B (da) 1985-08-19
JPS6254118B2 (no) 1987-11-13
DK148632C (da) 1986-03-03
AU4268278A (en) 1979-06-28
US4591583A (en) 1986-05-27
DK564178A (da) 1979-06-23
US4372894A (en) 1983-02-08
JPS54109951A (en) 1979-08-29
NO154751B (no) 1986-09-08
US4386081A (en) 1983-05-31
CA1140049A (en) 1983-01-25
SG82383G (en) 1985-03-08
NO784330L (no) 1979-06-25
DK148632B (da) 1985-08-19

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