NO784331L - Aromatiske derivater, farmasoeytiske preparater og fremgangsmaate til bekjempelse av virusinfeksjoner - Google Patents

Aromatiske derivater, farmasoeytiske preparater og fremgangsmaate til bekjempelse av virusinfeksjoner

Info

Publication number
NO784331L
NO784331L NO784331A NO784331A NO784331L NO 784331 L NO784331 L NO 784331L NO 784331 A NO784331 A NO 784331A NO 784331 A NO784331 A NO 784331A NO 784331 L NO784331 L NO 784331L
Authority
NO
Norway
Prior art keywords
pharmaceuticals
procedures
virus infections
aromatic derivatives
fighting
Prior art date
Application number
NO784331A
Other languages
English (en)
Other versions
NO156611B (no
NO156611C (no
Inventor
Aake J E Helgstrand
Karl Nils-Gunnar Johansson
Alfons Misiorny
Jan-Olof Noren
Goeran Bertil Stening
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of NO784331L publication Critical patent/NO784331L/no
Publication of NO156611B publication Critical patent/NO156611B/no
Publication of NO156611C publication Critical patent/NO156611C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3886—Acids containing the structure -C(=X)-P(=X)(XH)2 or NC-P(=X)(XH)2, (X = O, S, Se)
    • C07F9/3891—Acids containing the structure -C(=X)-P(=X)(XH)2, (X = O, S, Se)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
    • C07F9/4065—Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO784331A 1977-12-22 1978-12-21 Analogifremgangsmaate for fremstilling av terapeutiske virksomme derivater av hydroksykarbonylfosfonsyre. NO156611C (no)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB5358177 1977-12-22
GB5358077 1977-12-22
GB5358377 1977-12-22
GB5358277 1977-12-22
GB7828553 1978-07-03
GB7828552 1978-07-03
GB7828548 1978-07-03
GB7828555 1978-07-03

Publications (3)

Publication Number Publication Date
NO784331L true NO784331L (no) 1979-06-25
NO156611B NO156611B (no) 1987-07-13
NO156611C NO156611C (no) 1987-10-21

Family

ID=27571200

Family Applications (2)

Application Number Title Priority Date Filing Date
NO784331A NO156611C (no) 1977-12-22 1978-12-21 Analogifremgangsmaate for fremstilling av terapeutiske virksomme derivater av hydroksykarbonylfosfonsyre.
NO784330A NO154751C (no) 1977-12-22 1978-12-21 Analogifremgangsmaate for fremstilling av terapeutisk virksomme hydroksykarbonylfosfonsyreestere.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO784330A NO154751C (no) 1977-12-22 1978-12-21 Analogifremgangsmaate for fremstilling av terapeutisk virksomme hydroksykarbonylfosfonsyreestere.

Country Status (14)

Country Link
US (4) US4372894A (no)
EP (2) EP0003275B1 (no)
JP (2) JPS54106431A (no)
AT (1) AT369017B (no)
AU (1) AU530031B2 (no)
CA (2) CA1144937A (no)
DE (2) DE2861045D1 (no)
DK (2) DK148631C (no)
FI (2) FI65438C (no)
HK (1) HK33584A (no)
IE (1) IE48011B1 (no)
MY (1) MY8500058A (no)
NO (2) NO156611C (no)
SG (1) SG82383G (no)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1144937A (en) * 1977-12-22 1983-04-19 Dke J.E. Helgstrand Aromatic derivatives, pharmaceutical compositions and methods for combatting virus infections
GB8501374D0 (en) * 1985-01-18 1985-02-20 Wellcome Found Treatment of aids
US4806532A (en) * 1985-10-08 1989-02-21 Mayo Foundation For Medical Education And Research Inhibition of epithelial phosphate transport
US6492352B1 (en) * 1985-10-31 2002-12-10 Astra Lakemedel Aktiebolag Method for the control and treatment of acquired immunodeficiency syndrome (AIDS)
US5166386A (en) * 1989-09-18 1992-11-24 E. R. Squibb & Sons, Inc. Process of making isoprenoid phosphinylformic acid squalene synthetase inhibitors
US5025003A (en) * 1989-09-18 1991-06-18 E. R. Squibb & Sons, Inc. Isoprenoid phosphinylformic acid squalene synthetase inhibitors
US5463092A (en) * 1989-11-22 1995-10-31 Vestar, Inc. Lipid derivatives of phosphonacids for liposomal incorporation and method of use
US5132414A (en) * 1990-05-10 1992-07-21 Dana-Farber Cancer Institute, Inc. Dideoxynucleoside-5'-phosphonoformic acid compounds
US5696277A (en) * 1994-11-15 1997-12-09 Karl Y. Hostetler Antiviral prodrugs
US7517858B1 (en) 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
US6096730A (en) * 1997-07-24 2000-08-01 University Of Kentucky Research Foundation Phosphonated agents and their antiangiogenic and antitumorigenic use
US5869469A (en) * 1997-08-18 1999-02-09 Queen's University At Kingston Phosphonocarboxylate compounds for treating amyloidosis
WO1999008685A1 (en) * 1997-08-18 1999-02-25 Queen's University At Kingston Phosphono-carboxylate compounds for treating amyloidosis
EP1054664B1 (en) * 1998-02-11 2012-08-08 BHI Limited Partnership Method for modulating macrophage activation
US20040002079A1 (en) * 1998-02-11 2004-01-01 Gunn Robert B. Sodium-phosphate cotransporter in lithium therapy for the treatment of mental illness
US20020022657A1 (en) * 1998-02-11 2002-02-21 Francine Gervais Methods for modulating neuronal cell death
US6329356B1 (en) 1998-04-10 2001-12-11 Neurochem, Inc. Phosphono-carboxylate compounds for treating amyloidosis
US6310073B1 (en) * 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
DE60042896D1 (de) * 1999-04-28 2009-10-15 Bellus Health Int Ltd Zusammensetzungen und verfahren zur behandlung von amyloidosis mit sulphonatderivaten
US6562836B1 (en) 1999-05-24 2003-05-13 Queen's University Of Kingston Methods and compounds for inhibiting amyloid deposits
AU8431301A (en) 1999-12-23 2001-11-20 Neurochem (International) Limited Compounds and methods for modulating cerebral amyloid angiopathy
ATE337309T1 (de) * 2002-04-01 2006-09-15 Pfizer Pyranon- und pyrandioninhibitoren der rna- abhängigen rna-polymerase des hepatitis-c-virus
DOP2003000641A (es) * 2002-05-10 2003-11-15 Pfizer Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan
US7148226B2 (en) * 2003-02-21 2006-12-12 Agouron Pharmaceuticals, Inc. Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
US20040214178A1 (en) * 2003-04-24 2004-10-28 Agouron Pharmaceuticals, Inc. Reporter-selectable Hepatitis C virus replicon
US20070010573A1 (en) 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7244764B2 (en) 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US7414076B2 (en) 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
NZ552874A (en) * 2004-08-18 2010-04-30 Pfizer Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
ITMI20041822A1 (it) * 2004-09-24 2004-12-24 Pharmaproducts Uk Ltd "agente terapeutico utile per il trattamento di neoplasie plasmacellulari"
EP1817305A2 (en) * 2004-11-16 2007-08-15 Neurochem (International) Limited Compounds for the treatment of cns and amyloid associated diseases
CN101128421A (zh) 2004-12-22 2008-02-20 神经化学（国际）有限公司 治疗淀粉样相关疾病用的方法与组合物
MX2008008213A (es) * 2005-12-22 2008-09-03 Neurochem Int Ltd Tratamiento de trastornos renales, nefropatia diabetica y dislipidemias.
FI3851447T3 (fi) 2006-10-12 2023-11-15 Bellus Health Inc Menetelmiä, yhdisteitä, koostumuksia ja vehikkeleitä 3-amino-1-propaanisulfonihapon vapauttamiseksi
EP2120905A1 (en) * 2006-12-22 2009-11-25 BELLUS Health (International) Limited Methods, compounds, and compositions for treating metabolic disorders and diabetes
US20080293648A1 (en) * 2007-01-05 2008-11-27 Saha Pharmaceuticals, Inc. Compositions and Methods for Cancer Treatment
DE102012103717A1 (de) * 2012-04-27 2013-11-14 Westfälische Wilhelms-Universität Münster Arzneimittel zur Behandlung von Tumorerkrankungen
US10374256B2 (en) * 2013-12-19 2019-08-06 Ube Industries, Ltd. Nonaqueous electrolyte solution, electricity storage device using same, and phosphonoformic acid compound used in same
ES2578902B1 (es) * 2014-12-29 2017-07-07 Agencia Pública Empresarial Sanitaria Costa Del Sol Uso de análogos del ión pirofosfato para el tratamiento de la infección por VPH
CN109400645A (zh) * 2017-08-18 2019-03-01 四川海思科制药有限公司 一种磷酸衍生物及制备方法和用途
WO2025106974A1 (en) * 2023-11-17 2025-05-22 The Board Of Trustees Of The Leland Stanford Junior University Prodrug moieties and compounds comprising the same

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155597A (en) * 1961-06-23 1964-11-03 Monsanto Co Extractive separation process
US3846512A (en) * 1968-05-24 1974-11-05 Du Pont Carbamoylphosphonates
CH513590A (de) 1968-05-24 1971-10-15 Du Pont Carbamoylphosphonat enthaltender Pflanzenwachstumsregler
US3997544A (en) * 1968-05-24 1976-12-14 E. I. Du Pont De Nemours And Company Plant growth regulant carbamoylphosphonates
US3533995A (en) * 1968-08-27 1970-10-13 Fmc Corp Heat stabilization of polyester resin with alkyl dialkoxyphosphinyl formate
US3849102A (en) * 1969-08-14 1974-11-19 Du Pont Plant growth regulant method
GB1317768A (en) 1969-08-14 1973-05-23 Du Pont Plant growth regulants
US3767795A (en) * 1971-02-25 1973-10-23 Abbott Lab Method for combating certain virus infection
US3943201A (en) * 1973-07-23 1976-03-09 E. I. Du Pont De Nemours And Comapny Alkoxy carboxycarbonylphosphonic acid esters
BR7405998D0 (pt) 1973-07-23 1975-05-13 Du Pont Processos compostos e composicoes para controlar o crescimmento de plantas
US4017297A (en) * 1975-08-29 1977-04-12 E. I. Du Pont De Nemours And Company Phosphonates for the control of bindweed
US4052439A (en) * 1976-04-30 1977-10-04 Abbott Laboratories Carboxylic esters of phosphonoacetic acid
US4092412A (en) * 1976-04-30 1978-05-30 Abbott Laboratories Treatment of herpes simplex infections
CA1069526A (en) * 1976-04-30 1980-01-08 Thomas R. Herrin Phosphorus esters of phosphonoacetic acid
SE7607496L (sv) * 1976-07-01 1978-01-02 Astra Laekemedel Ab Sett for bekempning av virusinfektioner
CA1144937A (en) * 1977-12-22 1983-04-19 Dke J.E. Helgstrand Aromatic derivatives, pharmaceutical compositions and methods for combatting virus infections

Also Published As

Publication number Publication date
FI68626B (fi) 1985-06-28
DK148631C (da) 1986-03-03
NO154751C (no) 1986-12-17
AT369017B (de) 1982-11-25
US4591583A (en) 1986-05-27
EP0003007A3 (en) 1979-08-08
EP0003275A1 (en) 1979-08-08
SG82383G (en) 1985-03-08
JPS6254118B2 (no) 1987-11-13
DE2861729D1 (en) 1982-05-19
NO156611B (no) 1987-07-13
US4536400A (en) 1985-08-20
FI68626C (fi) 1985-10-10
ATA921778A (de) 1982-04-15
IE48011B1 (en) 1984-09-05
CA1144937A (en) 1983-04-19
NO154751B (no) 1986-09-08
NO156611C (no) 1987-10-21
EP0003007A2 (en) 1979-07-11
US4372894A (en) 1983-02-08
FI65438B (fi) 1984-01-31
DE2861045D1 (en) 1981-11-26
CA1140049A (en) 1983-01-25
JPS54106431A (en) 1979-08-21
US4386081A (en) 1983-05-31
DK564278A (da) 1979-06-23
JPS6330885B2 (no) 1988-06-21
MY8500058A (en) 1985-12-31
DK148632C (da) 1986-03-03
JPS54109951A (en) 1979-08-29
HK33584A (en) 1984-04-27
FI783931A7 (fi) 1979-06-23
FI783932A7 (fi) 1979-06-23
FI65438C (fi) 1984-05-10
AU4268278A (en) 1979-06-28
AU530031B2 (en) 1983-06-30
DK148632B (da) 1985-08-19
DK564178A (da) 1979-06-23
EP0003275B1 (en) 1981-09-02
NO784330L (no) 1979-06-25
IE782493L (en) 1979-06-22
DK148631B (da) 1985-08-19
EP0003007B1 (en) 1982-04-07

Similar Documents

Publication Publication Date Title
NO784331L (no) Aromatiske derivater, farmasoeytiske preparater og fremgangsmaate til bekjempelse av virusinfeksjoner
NL190519B (nl) 4-gesubstitueerde fenylazijnzuurverbindingen, alsmede farmaceutische preparaten.
NL183822C (nl) Door fluor gesubstitueerde 5-fenoxybenzyloxycarbonylderivaten, alsmede met toepassing daarvan gevormd insecticide of acaricide preparaat.
NL7805647A (nl) Mevalonolactonderivaten, hun gebruik en bereiding.
DK313276A (da) 2',4-dichlor-4'-benzoylureido-diphenylethere, fremgangsmade til deres fremstilling og deres anvendelse som insecticider
NL7810562A (nl) Ureumderivaten, werkwijze ter bereiding ervan alsmede farmaceutische preparaten.
DK154777A (da) Substituerede phenoxybenzyloxycarbonylderivater fremgangsmade til deres fremstilling og deres anvendelse som insecticider og acaricider
DK482176A (da) (1-phenyl-2-triazolyl-ethyl)-ether-derivater, fremgangsmade til deres fremstilling og anvendelse som fungicider
DK327477A (da) Halogenerede 1-azolyl-butan-derivater,fremgangsmaade til deresfremstilling og deres anvendelse som fungicider
NL7802892A (nl) Pseudotrisacchariden, werkwijzen ter bereiding ervan en farmaceutische preparaten.
IT7829368A0 (it) Derivato della crinazolina, procedimento per prepararlo e composizione farmaceutica che lo contiene.
NL7804345A (nl) Imidazoazinen en imidazodiazinen, werkwijze ter berei- ding daarvan en farmaceutische preparaten.
NL7803162A (nl) Nieuwe 1-aminoindaanderivaten, alsmede farmaceutische preparaten die deze bevatten.
NL188575C (nl) Triazolylacetofenonderivaten, geschikt als fungicide, alsmede dergelijke derivaten bevattende fungicide preparaten.
FI800770A7 (fi) Uudet indolijohdokset, niiden valmistaminen ja niiden käyttö lääkeaineina.
DK445078A (da) Fremgangsmaade til fremstilling af 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyklisk arylimidazoler og derivater deraf
DK5877A (da) Acylerede triazolyl-o,n-acetaler, fremgangsmade til deres fremstilling og deres anvendelse som fungicider
DK313878A (da) Indolderivater og fremgangsmaade til fremstilling deraf
DK387276A (da) Trifluormethylphenoxy-phenylurinstoffer, fremgangsmade til deres fremstilling og deres anvendelse som herbicider
DK582578A (da) 2,4-thiazolidindion-derivater og fremgangsmaade til deres fremstilling
DK331978A (da) Nitrosourinstofderivater og fremgangsmaade til femstilling deraf
NL7801216A (nl) Nieuwe benzeensulfonamide- en benzeencarboxami- dederivaten, bereiding en gebruik daarvan, als- mede farmaceutische preparaten die deze ver- bindingen bevatten.
DK442183D0 (da) Thiatriazin-derivater, fremgangsmader til fremstilling deraf og deres anvendelse som laegemidler
NO803551L (no) Substituerte 2-amino-3,4-dihydropyridinderivater, fremgangsmaate til deres fremstilling og deres anvendelse som legemiddel
NL7804168A (nl) Nieuwe naftyridinen, werkwijze ter bereiding daarvan, alsmede farmaceutische preparaten.