IL134619A0 - Phosphono-carboxylate compounds for treating amyloidosis - Google Patents

Phosphono-carboxylate compounds for treating amyloidosis

Info

Publication number
IL134619A0
IL134619A0 IL13461998A IL13461998A IL134619A0 IL 134619 A0 IL134619 A0 IL 134619A0 IL 13461998 A IL13461998 A IL 13461998A IL 13461998 A IL13461998 A IL 13461998A IL 134619 A0 IL134619 A0 IL 134619A0
Authority
IL
Israel
Prior art keywords
phosphono
carboxylate compounds
treating amyloidosis
amyloidosis
treating
Prior art date
Application number
IL13461998A
Original Assignee
Univ Kingston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/912,574 external-priority patent/US5869469A/en
Application filed by Univ Kingston filed Critical Univ Kingston
Publication of IL134619A0 publication Critical patent/IL134619A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
    • C07F9/4065—Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13461998A 1997-08-18 1998-04-10 Phosphono-carboxylate compounds for treating amyloidosis IL134619A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/912,574 US5869469A (en) 1997-08-18 1997-08-18 Phosphonocarboxylate compounds for treating amyloidosis
US7444598P 1998-02-11 1998-02-11
PCT/IB1998/000967 WO1999008685A1 (en) 1997-08-18 1998-04-10 Phosphono-carboxylate compounds for treating amyloidosis

Publications (1)

Publication Number Publication Date
IL134619A0 true IL134619A0 (en) 2001-04-30

Family

ID=26755679

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13461998A IL134619A0 (en) 1997-08-18 1998-04-10 Phosphono-carboxylate compounds for treating amyloidosis

Country Status (6)

Country Link
EP (1) EP1014994A1 (en)
JP (1) JP2001515039A (en)
CA (1) CA2300910C (en)
IL (1) IL134619A0 (en)
NZ (1) NZ550116A (en)
WO (1) WO1999008685A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1054664B1 (en) * 1998-02-11 2012-08-08 BHI Limited Partnership Method for modulating macrophage activation
MXPA00011213A (en) * 1998-05-15 2003-04-22 Neurochem Inc Use of amyloid inhibitors for modulating neuronal cell death.
US6310073B1 (en) 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
CA2369997C (en) * 1999-04-28 2009-11-17 Queen's University At Kingston Compositions and methods for treating amyloidosis
US6562836B1 (en) * 1999-05-24 2003-05-13 Queen's University Of Kingston Methods and compounds for inhibiting amyloid deposits
ES2300281T3 (en) 1999-12-03 2008-06-16 The Regents Of The University Of California At San Diego PHOSPHONATE COMPOUNDS.
CN1434706A (en) 1999-12-23 2003-08-06 神经化学公司 Compounds and methods for modulating cerebral anyloid angiopathy
EP1836161B1 (en) 2004-12-22 2016-07-20 BHI Limited Partnership Methods and compositions for treating amyloid-related diseases
CN101453999A (en) 2005-12-22 2009-06-10 神经化学（国际）有限公司 Treatment of renal disorders, diabetic nephopathy and dyslipidemias
MX339684B (en) 2006-10-12 2016-06-06 Bhi Ltd Partnership Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid.
AU2009206673B2 (en) 2008-01-25 2015-04-23 Chimerix, Inc. Methods of treating viral infections
PT2534150T (en) 2010-02-12 2017-05-02 Chimerix Inc Methods of treating viral infection
EP2563367A4 (en) 2010-04-26 2013-12-04 Chimerix Inc Methods of treating retroviral infections and related dosage regimes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1140049A (en) * 1977-12-22 1983-01-25 Dke J.E. Helgstran Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid
DE3940410A1 (en) * 1989-12-04 1991-06-06 Schering Ag NEW USE OF NMDA RECEPTOR ANTAGONISTS
ATE311864T1 (en) * 1993-03-29 2005-12-15 PROPANE-1,3-DISULPHONIC ACID AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF FOR THE TREATMENT OF AMYLOIDOSIS
AU6836394A (en) * 1993-06-01 1994-12-20 Cortex Pharmaceuticals, Inc. Use of metabotropic receptor agonists in progressive neurodegenerative deseases
US6043283A (en) * 1996-09-20 2000-03-28 Baylor College Of Medicine Tyramine compounds and their neuronal effects
WO1998013046A1 (en) * 1996-09-27 1998-04-02 Guilford Pharmaceuticals Inc. Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals
SE9604582D0 (en) * 1996-12-13 1996-12-13 Astra Ab Novel compounds

Also Published As

Publication number Publication date
NZ550116A (en) 2008-03-28
CA2300910A1 (en) 1999-02-25
EP1014994A1 (en) 2000-07-05
JP2001515039A (en) 2001-09-18
WO1999008685A1 (en) 1999-02-25
CA2300910C (en) 2008-02-26

Similar Documents

Publication Publication Date Title
GB9614871D0 (en) Compounds
GB9607120D0 (en) Compounds
HK1017351A1 (en) New compounds
IL134619A0 (en) Phosphono-carboxylate compounds for treating amyloidosis
GB9602326D0 (en) Compounds
GB9612153D0 (en) Compounds
GB9611461D0 (en) New compounds
PL334803A1 (en) Derivatives of imino-aza-antracyclinone for treating amyloidosis
GB9609187D0 (en) New compounds
GB9706352D0 (en) Compounds
GB9606933D0 (en) Compounds
GB9613276D0 (en) New compounds
GB9614440D0 (en) New compounds
SI0906288T1 (en) New compounds
GB9607438D0 (en) Compounds
GB9610902D0 (en) Compounds
GB9607122D0 (en) Compounds
GB9607126D0 (en) Compounds
GB9607154D0 (en) Compounds
GB9607155D0 (en) Compounds
GB9607215D0 (en) Compounds
GB9607218D0 (en) Compounds
GB9607256D0 (en) Compounds
GB9606931D0 (en) Compounds
GB9607444D0 (en) Compounds