JPS5520740A - Aminoalkoxybibenzyl and its acid addition salt - Google Patents

Aminoalkoxybibenzyl and its acid addition salt

Info

Publication number
JPS5520740A
JPS5520740A JP9404478A JP9404478A JPS5520740A JP S5520740 A JPS5520740 A JP S5520740A JP 9404478 A JP9404478 A JP 9404478A JP 9404478 A JP9404478 A JP 9404478A JP S5520740 A JPS5520740 A JP S5520740A
Authority
JP
Japan
Prior art keywords
formula
group
substituted
aminoalkoxybibenzyl
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9404478A
Other languages
Japanese (ja)
Other versions
JPS6121463B2 (en
Inventor
Ryoji Kikumoto
Jiichi Fukami
Hiroto Hara
Kunihiro Ninomiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kasei Corp
Original Assignee
Mitsubishi Kasei Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kasei Corp filed Critical Mitsubishi Kasei Corp
Priority to JP9404478A priority Critical patent/JPS5520740A/en
Priority to US05/943,621 priority patent/US4220603A/en
Priority to CA311,866A priority patent/CA1105931A/en
Priority to HU78MI636A priority patent/HU178306B/en
Priority to DK441878A priority patent/DK152040C/en
Priority to DD78208291A priority patent/DD139255A5/en
Priority to ES474575A priority patent/ES474575A1/en
Priority to SU782668855A priority patent/SU786883A3/en
Priority to IT28531/78A priority patent/IT1099778B/en
Priority to FI783049A priority patent/FI69840C/en
Priority to DE7878101092T priority patent/DE2861477D1/en
Priority to NO78783399A priority patent/NO146744C/en
Priority to EP78101092A priority patent/EP0001759B1/en
Priority to CS786561A priority patent/CS209918B2/en
Priority to ES480091A priority patent/ES480091A1/en
Priority to CS794084A priority patent/CS209917B2/en
Priority to US06/100,741 priority patent/US4323568A/en
Publication of JPS5520740A publication Critical patent/JPS5520740A/en
Publication of JPS6121463B2 publication Critical patent/JPS6121463B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:An aminoalkoxybibenzyl of formula I: [R1 is formula II or III (n is an integer 2W7); heterocyclic group may be substituted by a group selected from R4, COOR5, and hydroxyl group, or the methylene group forming the heterocyclic group may be substituted by formula IV; m is an integer 2W8; formula V is benzene ring which may be substituted by halogen, R9, etc.; R2, R3, and R8 are H or 1W3C alkyl groups; R5 is H or 1W8C alkyl group; R4 and R9 are 1W8C alkyl groups], and its acid addition salt.
EXAMPLE: 2-(2-Dimethylaminoethoxy)-4'-chlorobibenzyl.
USE: Useful as remedies or preventives aginst thrombosis, having an anticoagulating action, particularly blood platelet antiagglutinating action.
PROCESS: One mole of a halogenoalkoxybibenzyl of formula VI: (X is halogen) is reacted with 1W100 moles of an amine of the formula R1-H to give the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP9404478A 1977-10-07 1978-08-01 Aminoalkoxybibenzyl and its acid addition salt Granted JPS5520740A (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
JP9404478A JPS5520740A (en) 1978-08-01 1978-08-01 Aminoalkoxybibenzyl and its acid addition salt
US05/943,621 US4220603A (en) 1977-10-07 1978-09-19 Pharmaceutically active (omega-aminoalkoxy)bibenzyls
CA311,866A CA1105931A (en) 1977-10-07 1978-09-22 Pharmaceutically active (omega-aminoalkoxy) bibenzyls
HU78MI636A HU178306B (en) 1977-10-07 1978-10-03 Process for preparing pharmaceutically active /omega-amino-alkoxy/-dibenzyl derivatives and acid addition salts thereof
DK441878A DK152040C (en) 1977-10-07 1978-10-04 ANALOGY PROCEDURE FOR PREPARING BIBENZYL DERIVATIVES OR ACID ADDITION SALTS
DD78208291A DD139255A5 (en) 1977-10-07 1978-10-05 METHOD FOR THE PRODUCTION OF (OMEGA-AMINOALKOXY) -BIBENZYLENE AND ITS SAEUREADDITIONAL SALTS
ES474575A ES474575A1 (en) 1977-10-07 1978-10-06 (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances.
SU782668855A SU786883A3 (en) 1977-10-07 1978-10-06 Method of preparing (omega-aminoalkoxy)-bibenzyls or their salts
IT28531/78A IT1099778B (en) 1977-10-07 1978-10-06 (OMEGA-AMMINOLACOSSI) PHARMACEUTICALLY ACTIVE BONDS
FI783049A FI69840C (en) 1977-10-07 1978-10-06 FRUIT PROCESSING OF PHARMACEUTICAL ACTIVITIES (OMEGA-AMINOALCOXY) -DIBENYL DERIVATIVES
DE7878101092T DE2861477D1 (en) 1977-10-07 1978-10-06 (omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances
NO78783399A NO146744C (en) 1977-10-07 1978-10-06 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY (OMEGA-AMINOALCOXY) -DIBENZYL DERIVATIVES
EP78101092A EP0001759B1 (en) 1977-10-07 1978-10-06 (omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances
CS786561A CS209918B2 (en) 1977-10-07 1978-10-09 Method of preparation of the (omega-aminoalcoxy) bibenzyles
ES480091A ES480091A1 (en) 1977-10-07 1979-04-30 (Omega-aminoalkoxy) bibenzyls, processes for their preparation and pharmaceutical compositions containing these substances.
CS794084A CS209917B2 (en) 1977-10-07 1979-06-13 Method of preparation of the /omega-aminoalkoxy/bibenzyles
US06/100,741 US4323568A (en) 1977-10-07 1979-12-06 Pharmaceutically active (omega-aminoalkoxy)bibenzyls

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9404478A JPS5520740A (en) 1978-08-01 1978-08-01 Aminoalkoxybibenzyl and its acid addition salt

Publications (2)

Publication Number Publication Date
JPS5520740A true JPS5520740A (en) 1980-02-14
JPS6121463B2 JPS6121463B2 (en) 1986-05-27

Family

ID=14099557

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9404478A Granted JPS5520740A (en) 1977-10-07 1978-08-01 Aminoalkoxybibenzyl and its acid addition salt

Country Status (1)

Country Link
JP (1) JPS5520740A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02304022A (en) * 1989-05-18 1990-12-17 Mitsubishi Kasei Corp Serotonin antagonistic agent
EP0600717A1 (en) 1992-11-30 1994-06-08 Sankyo Company Limited Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6447372U (en) * 1987-09-17 1989-03-23

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02304022A (en) * 1989-05-18 1990-12-17 Mitsubishi Kasei Corp Serotonin antagonistic agent
JPH0544926B2 (en) * 1989-05-18 1993-07-07 Mitsubishi Chem Ind
EP0600717A1 (en) 1992-11-30 1994-06-08 Sankyo Company Limited Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis

Also Published As

Publication number Publication date
JPS6121463B2 (en) 1986-05-27

Similar Documents

Publication Publication Date Title
JPS5495552A (en) Prostacyline derivative and its preparation
ES2008962A6 (en) New-quanidino-thiazol compounds, their preparation, and use as intermediates of famotidine process.
JPS5520740A (en) Aminoalkoxybibenzyl and its acid addition salt
ES8401926A1 (en) Hydroxybenzylamino-aryl compounds, process for preparing and pharmaceutical compositions containing the same.
JPS572290A (en) Production of penem-3-carboxylic derivative
JPS579771A (en) Tetrazole derivative
ATE28648T1 (en) 7-OXO-4-THIA-1-AZABICYCLO(3,2,0)HEPTANE DERIVATIVES
JPS55118494A (en) Novel phosphorylcholine compound, its preparation, and antitumor agent comprising it
ES8603434A1 (en) 1,2,4-Triazolylpropanols, and their production and use.
JPS5692261A (en) Novel cyclohexanecarboxylic derivative and its preparation
FR2438034A1 (en) METHYL TRITHIOCARBONATE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR USE FOR CONTROLLING INSECTS AND MITES
JPS5515457A (en) Dithiocarbamic acid derivative
JPS5772981A (en) 1,8-naphthyridine derivative and its salt
JPS5639085A (en) Chromone derivative and its preparation
JPS5531086A (en) Prepartion of 5,6-epoxy-1,2,6-trimethyl-tricyclo 5.3.2.02,7 dodecane
JPS54106481A (en) Novel 2,3-dioxopiperazine derivative and its preparation
JPS5759856A (en) Benzene derivative
JPS56108794A (en) Preparation of 7-amino-3-thiadiazolylthiomethyl-3-cephem- 4-carboxylic acid derivative
JPS5511503A (en) Condensed heterocyclic compound
JPS56127378A (en) 2-alkoxyindolizine derivative and its preparation
JPS5527142A (en) Novel 1-phthalazone derivative
JPS572289A (en) Production of penem-3-carboxylic derivative
JPS55118498A (en) Phosphonic derivative and its preparation
JPS55124757A (en) Sulfur-containing compound
JPS5528945A (en) Prostacycline-family compound and its preparation