ES472641A1 - Procedimiento para la obtencion de propenil-aminas - Google Patents

Procedimiento para la obtencion de propenil-aminas

Info

Publication number
ES472641A1
ES472641A1 ES472641A ES472641A ES472641A1 ES 472641 A1 ES472641 A1 ES 472641A1 ES 472641 A ES472641 A ES 472641A ES 472641 A ES472641 A ES 472641A ES 472641 A1 ES472641 A1 ES 472641A1
Authority
ES
Spain
Prior art keywords
processes
production
pharmaceutical compositions
compositions containing
propenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472641A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27429271&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES472641(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from CH1020377A external-priority patent/CH632251A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES472641A1 publication Critical patent/ES472641A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms

Abstract

Procedimiento para la obtención de propenil-aminas, dicho procedimiento puede realizarse en un disolvente inerte tal como un alcanol inferior, por ejemplo el etanol, eventualmente en mezcla acuosa, un disolvente hidrocarburo aromático, por ejemplo el benceno o el tolueno, un éter cíclico, por ejemplo el dioxano, o un disolvente dialquilamida de un ácido carboxílico, por ejemplo la dimetilformamida. La temperatura de la reacción está comprendida de preferencia entre temperatura ambiente y la temperatura de ebullición de la mezcla de la reacción.
ES472641A 1977-08-19 1978-08-17 Procedimiento para la obtencion de propenil-aminas Expired ES472641A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1020277 1977-08-19
CH1020377A CH632251A5 (en) 1977-08-19 1977-08-19 Process for preparing novel 2-naphthyl-substituted, cyclic, N-allylamine derivatives
CH1291077 1977-10-24
CH1290977 1977-10-24

Publications (1)

Publication Number Publication Date
ES472641A1 true ES472641A1 (es) 1979-10-16

Family

ID=27429271

Family Applications (1)

Application Number Title Priority Date Filing Date
ES472641A Expired ES472641A1 (es) 1977-08-19 1978-08-17 Procedimiento para la obtencion de propenil-aminas

Country Status (14)

Country Link
US (1) US4680291A (es)
EP (1) EP0000896B1 (es)
JP (1) JPS5441855A (es)
CA (1) CA1111852A (es)
DE (1) DE2862103D1 (es)
DK (1) DK152114C (es)
ES (1) ES472641A1 (es)
FI (1) FI65774C (es)
IE (1) IE47314B1 (es)
IL (1) IL55382A (es)
IT (1) IT1098253B (es)
MY (1) MY8500040A (es)
NZ (1) NZ188170A (es)
PT (1) PT68448A (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3020113A1 (de) * 1979-06-08 1980-12-18 Sandoz Ag 2-(1-naphthyl)piperidin-derivat, dessen herstellung sowie die verwendung als antimykotika
EP0024587B1 (en) * 1979-08-22 1984-11-14 Sandoz Ag Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
NL8003141A (nl) * 1980-05-30 1982-01-04 Akzo Nv Biologisch aktieve tricyclische aminen.
IT1150211B (it) * 1981-03-02 1986-12-10 Abbott Lab 1,2,3,4-tetraidronaftaleni sostituiti con amminoalchili adazione farmaceutica
CH653028A5 (de) * 1982-02-03 1985-12-13 Sandoz Ag Benzthiophenallylamin-verbindungen und verfahren zu ihrer herstellung.
JPS6145A (ja) * 1984-06-09 1986-01-06 Kaken Pharmaceut Co Ltd Ｎ‐（４‐ｔｅｒｔ‐ブチルベンジル）‐Ｎ‐メチル‐１‐ナフチルメチルアミンおよびそれを有効成分とする抗真菌剤
US5334628A (en) * 1984-06-09 1994-08-02 Kaken Pharmaceutical Co., Ltd. Amine derivatives, processes for preparing the same and fungicides containing the same
JPH0676285B2 (ja) * 1985-11-01 1994-09-28 三井東圧化学株式会社 ベンジルアミン誘導体、その製造法およびその用途
EP0254677A1 (en) * 1986-07-08 1988-01-27 Sandoz Ag Antimycotic 6-phenyl-2-hexen-4-ynamines
US5084476A (en) * 1986-07-15 1992-01-28 Hoffmann-La Roche Inc. Tetrahydronaphthalene and indane derivatives
US5234946A (en) * 1987-11-27 1993-08-10 Banyu Pharmaceutical Co., Ltd. Substituted alkylamine derivatives
JPH03105465U (es) * 1990-02-16 1991-10-31
GB9513750D0 (en) * 1995-07-06 1995-09-06 Sandoz Ltd Use of allylamines
CA2261916A1 (en) * 1996-08-01 1998-02-12 Dowelanco Llc 4-substituted quinoline derivatives having fungicidal activity
US6117884A (en) * 1997-07-31 2000-09-12 Daeuble; John 4-substituted quinoline derivatives having fungicidal activity
JP4509327B2 (ja) * 2000-08-03 2010-07-21 ダイセル化学工業株式会社 Ｎ，ｎ−ジ置換−４−アミノクロトン酸エステルの製造方法
GB0320312D0 (en) * 2003-08-29 2003-10-01 Novartis Ag Purification process
US20050197512A1 (en) * 2003-08-29 2005-09-08 Ulrich Beutler Purification process
CA2570245A1 (en) * 2004-07-02 2006-01-12 Warner-Lambert Company Llc Compositions and methods for treating pathological infections
JP2009502258A (ja) * 2005-07-21 2009-01-29 ノミール・メディカル・テクノロジーズ・インコーポレーテッド 標的部位の生物学的汚染物質のレベルを下げる方法
US20090082469A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched terbinafine
WO2017132912A1 (zh) * 2016-02-03 2017-08-10 华东理工大学 苯并脂肪环取代烷基胺类化合物及其用途
CN108084125B (zh) 2016-11-23 2020-08-18 华东理工大学 苯并杂环烷基胺类化合物及其用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE609151C (de) * 1930-02-01 1935-02-08 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von Aminoalkoholen mit sekundaerer oder tertiaerer Aminogruppe
US2601275A (en) * 1949-10-29 1952-06-24 Givaudan Corp Aromatic chlorethylamines and their salts
DK106378C (da) * 1962-10-19 1967-01-30 Koninklijke Pharma Fab Nv Fremgangsmåde til fremstilling af N-substituerede 1-phenyl-2-aminoalkaner eller syreadditionssalte heraf.
GB1041987A (en) * 1964-09-03 1966-09-07 Beecham Group Ltd Acetylenic compounds
GB1134715A (en) * 1966-02-24 1968-11-27 Geistlich Soehne Ag Bisphenylalkenylamine derivatives
US3784642A (en) * 1967-11-03 1974-01-08 E Jenny 1-amine-cyclobutene
BE786748A (fr) * 1971-07-26 1973-01-26 Basf Ag 1-aminomethyl-indanes-n-substitues
BE791133A (fr) * 1971-11-10 1973-05-09 Calgon Corp Nouveaux monomeres cationiques et leurs procedes de fabrication
BE791538A (fr) * 1971-11-19 1973-05-17 Basf Ag 1-aminomethyl-acenaphtenes, leur preparation et leurs utillisations therapeutiques
BE794598A (fr) * 1972-01-28 1973-05-16 Richardson Merrell Inc Nouveaux derives olefiniques de piperidines substituees en 4 et leur procede de preparation
JPS4930346A (es) * 1972-07-18 1974-03-18
US4139560A (en) * 1974-02-22 1979-02-13 Ciba Geigy Corporation Nonylamines
HU169507B (es) * 1974-09-25 1976-12-28
DE2716943C2 (de) * 1976-04-28 1986-08-14 Sandoz-Patent-GmbH, 7850 Lörrach N-(3-Phenyl-2-propenyl)-N-(1-naphthylmethyl)-amine, ihre Verwendung und Herstellung

Also Published As

Publication number Publication date
EP0000896A3 (en) 1979-05-30
IT1098253B (it) 1985-09-07
PT68448A (fr) 1978-09-01
FI65774B (fi) 1984-03-30
DE2862103D1 (en) 1982-11-18
IL55382A0 (en) 1978-10-31
EP0000896B1 (en) 1982-10-13
IL55382A (en) 1981-12-31
FI65774C (fi) 1984-07-10
MY8500040A (en) 1985-12-31
JPS6317050B2 (es) 1988-04-12
NZ188170A (en) 1981-05-01
US4680291A (en) 1987-07-14
DK152114C (da) 1988-06-20
CA1111852A (en) 1981-11-03
IT7826835A0 (it) 1978-08-18
IE47314B1 (en) 1984-02-22
FI782446A (fi) 1979-02-20
DK354678A (da) 1979-02-20
EP0000896A2 (en) 1979-03-07
DK152114B (da) 1988-02-01
IE781670L (en) 1979-02-19
JPS5441855A (en) 1979-04-03

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